Ann Coloproctol > Epub ahead of print |
|
Characteristic | Data |
---|---|
No. of patients | 400 |
Age (yr) | 64 (25–86) |
Sex, male:female | 267:133 |
Body mass index (kg/m2) | 23.0 (14.3–34.4) |
Location, RS:Ra:Rb | 115:172:112 |
pStage, I:II:III:IV | 111:98:120:23 |
Approach, Lap:Open | 272:128 |
Procedure, AR:LAR:ISR | 55:308:37 |
Ano-anastomotic distance (cm) | 6 (2–15) |
Postoperative complications | |
No. of patients with POCs | 120 (30.0) |
Anastomotic leakage | 50 (12.5) |
Bowel obstructiona | 49 (12.3) |
SRCs | 33 (18.2) |
Postoperative hospitalization (day) | 13 (7–97) |
Reoperation | 19 (4.8) |
Mortality, within 30 days of surgery | 1 (0.3) |
Values are presented as number only, median (range), or number (%).
RS, rectosigmoid; Ra, upper rectum; Rb, lower rectum; pStage, pathologic stage; Lap, laparoscopic surgery; Open, open surgery; AR, anterior resection; LAR, lower anterior resection; ISR, intersphincteric resection; POC, postoperative complication; SRC, stoma-related complication.
Variable |
Group |
P-value | |
---|---|---|---|
DS (–) (n=247) | DS (+) (n=153) | ||
Oral ingestion, POD | 6 (4–41) | 4 (2–18) | 0.010 |
Complicationa | |||
Total | |||
All grades | 57 (23.1) | 89 (58.2) | < 0.01 |
G1 | 6 (2.4) | 19 (12.4) | < 0.01 |
G2 | 34 (13.8) | 42 (27.5) | < 0.01 |
G3 | 17 (6.9) | 28 (18.3) | < 0.01 |
G3a | 5 (2.0) | 21 (13.7) | < 0.01 |
G3b | 12 (4.9) | 7 (4.6) | 0.900 |
G4 | 0 (0) | 0 (0) | - |
G5 | 0 (0) | 1 (0.7) | 0.200 |
Leakage | |||
All grades | 27 (10.9) | 23 (15.0) | 0.310 |
G1 | 0 (0) | 11 (7.2) | < 0.01 |
G2 | 16 (6.5) | 12 (7.8) | 0.600 |
G3a | 0 (0) | 0 (0) | - |
G3b | 11 (4.5) | 0 (0) | 0.010 |
Bowel obstruction | |||
All grades | 10 (4.0) | 39 (25.5) | < 0.01 |
G1 | 0 (0) | 0 (0) | - |
G2 | 4 (1.6) | 13 (8.5) | < 0.01 |
G3a | 5 (2.0) | 21 (13.7) | < 0.01 |
G3b | 1 (0.4) | 5 (3.3) | 0.020 |
Surgical site infection | |||
All grades | 6 (2.4) | 3 (2.0) | 0.560 |
G1 | 6 (2.4) | 2 (1.3) | 0.440 |
G2 | 0 (0) | 0 (0) | - |
G3a | 0 (0) | 0 (0) | - |
G3b | 0 (0) | 1 (0.7) | 0.200 |
Urinary disturbance | |||
All grades | 14 (5.7) | 11 (7.2) | 0.550 |
G1 | 0 (0) | 0 (0) | - |
G2 | 14 (5.7) | 11 (7.2) | 0.550 |
G3a | 0 (0) | 0 (0) | - |
G3b | 0 (0) | 0 (0) | - |
Hospitalization (day) | 12 (7–85) | 15 (8–97) | 0.020 |
Reoperation | 12 (4.9) | 7 (4.6) | 0.900 |
a According to Common Terminology Criteria for Adverse Events (CTCAE ver. 4.0; National Cancer Institute, Bethesda, MD, USA) [10].
Complication | G1 | G2 | G3a | G3b | Total |
---|---|---|---|---|---|
Stoma outlet syndrome | 0 | 0 | 15 | 4 | 19 |
Electrolyte imbalance | 0 | 6 | 0 | 1 | 7 |
Peristomal dermatitis | 6 | 0 | 0 | 0 | 6 |
Mucocutaneous separation of stoma | 0 | 0 | 0 | 1 | 1 |
Total | 6 | 6 | 15 | 6 | 33 |
G, grade.
According to Common Terminology Criteria for Adverse Events (CTCAE ver. 4.0; National Cancer Institute, Bethesda, MD, USA) [10].
Comparison with PEG-ELS and conventional colon preparation in colonic surgery.1993 March;9(1)
Reappraisal of AJCC Staging System in Colorectal Cancer.2002 August;18(4)
DCC Gene and Protein Expression in Colorectal Cancer.2003 February;19(1)