Annals of Coloproctology

Volume 34(1); February 2018

Editorial

Transanal Total Mesorectal Excision for Rectal Cancer: Perioperative and Oncological Outcomes: Hyuk Hur; Ann Coloproctol. 2018;34(1):1-3. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.1

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Upgrading Your Surgical Skills Through Preceptorship
David V. Feliciano, Conor P. Delaney, Philip Schauer, Danny M. Takanishi, Lori Arviso Alford, Walter Medlin, Ajit K. Sachdeva
Journal of the American College of Surgeons.2021; 233(3): 487. CrossRef

Original Articles

Perioperative Serum Carcinoembryonic Antigen Ratio Is a Prognostic Indicator in Patients With Stage II Colorectal Cancer: Jinsun Woo, Jungbin Kim, Inseok Park, Hyunjin Cho, Geumhee Gwak, Keun Ho Yang, Byung-Noe Bae, Ki Hwan Kim; Ann Coloproctol. 2018;34(1):4-10. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.4

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Purpose

The aim of this study was to evaluate whether the perioperative carcinoembryonic antigen (CEA) ratio could be used as a determinant for adjuvant therapy after curative surgery in stage II colorectal cancer.

Methods

Data for 119 patients with stage II colorectal cancer who underwent radical surgery between 2010 and 2013 were collected. The perioperative CEA ratio was defined as the postoperative/preoperative serum CEA level, and the patients were grouped according to their perioperative CEA ratios: high ratio (≥0.5) and low ratio (<0.5). Overall survival rates were calculated, and their prognostic significances were analyzed.

Results

The overall survival rates of the high and the low perioperative CEA groups were 68.2% and 86.8%, respectively (P = 0.033). In patients with normal preoperative CEA levels (<5 ng/mL), the high perioperative CEA ratio group showed a worse survival rate than the low perioperative CEA ratio group (71.7% vs. 100.0%, P = 0.007). In patients with high preoperative CEA levels (≥5 ng/mL), the high perioperative CEA ratio group showed a worse survival rate than the low perioperative CEA ratio group (33.3% vs. 75.0%, P = 0.036). In the multivariate analysis, perioperative CEA ratio (P = 0.046), age (P = 0.034), and venous invasion (P = 0.015) were independent prognostic factors for survival.

Conclusion

The perioperative CEA ratio is a prognostic indicator for stage II colorectal cancer. Patients with normal preoperative serum CEA levels might also be considered for adjuvant therapy if their perioperative CEA ratios are higher than 0.5.

Citations

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Tumor regression and immunity in combination therapy with anti-CEA chimeric antigen receptor T cells and anti-CEA-IL2 immunocytokine
Seung E. Cha, Maciej Kujawski, Paul J. Yazaki, Christine Brown, John E. Shively
OncoImmunology.2021;[Epub] CrossRef
Prognostic Impact of Pretreatment Elevated and Normalized Carcinoembryonic Antigen Levels After Neoadjuvant Chemoradiotherapy in Resected Locally Advanced Rectal Cancer Patients
Jianyuan Song, Zhuhong Chen, Daxin Huang, Benhua Xu
Cancer Management and Research.2021; Volume 13: 3713. CrossRef
Association between Primary Perioperative CEA Ratio, Tumor Site, and Overall Survival in Patients with Colorectal Cancer
Thomas A. Odeny, Nicole Farha, Hannah Hildebrandand, Jessica Allen, Wilfred Vazquez, Maximillian Martinez, Ravi Kumar Paluri, Anup Kasi
Journal of Clinical Medicine.2020; 9(12): 3848. CrossRef

Is a One Night Delay of Surgery Safe in Patients With Acute Appendicitis?: Jae Min Lee, Beom Seok Kwak, Young Jin Park; Ann Coloproctol. 2018;34(1):11-15. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.11

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Abstract PDF

Purpose

With varied reports on the impact of time to appendectomy on clinical outcomes, the purpose of this study was to determine the effect of preoperative in-hospital delay on the outcome for patients with acute appendicitis.

Methods

A retrospective review of 1,076 patients who had undergone an appendectomy between January 2010 and December 2013 was conducted.

Results

The outcomes of surgery and the pathologic findings were analyzed according to elapsed time. The overall elapsed time from onset of symptoms to surgery was positively associated with advanced pathology, increased number of complications, and prolonged hospital stay. In-hospital elapsed time was not associated with any advanced pathology (P = 0.52), increased number of postoperative complications (P = 0.14), or prolonged hospital stay (P = 0.24). However, the complication rate was increased when the in-hospital elapsed time exceeded 18 hours.

Conclusion

Advanced pathology and postoperative complication rate were associated with overall elapsed time from symptom onset to surgery rather than in-hospital elapse time. Therefore, a short-term delay of an appendectomy should be acceptable.

Citations

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Is the performance of acute appendectomy at different times of day equal, in terms of postoperative complications, readmission, death, and length of hospital stay? A Swedish retrospective cohort study of 4950 patients
Petter Nyström, Martin Nordberg, Lennart Boström
European Journal of Trauma and Emergency Surgery.2024; 50(3): 791. CrossRef
Does the timing of appendectomy affect outcomes and postoperative complications?
María San Basilio, Carlos Delgado-Miguel, Carla Ramírez-Amorós, María Sarmiento, Lucas Moratilla-Lapeña, Arturo Almeyda, Ricardo Mejía, Leopoldo Martínez
Pediatric Surgery International.2023;[Epub] CrossRef
Timing of surgical operation for patients with intra-abdominal infection: A systematic review and meta-analysis
Shu-Rui Song, Yang-Yang Liu, Yu-Ting Guan, Ruo-Jing Li, Lei Song, Jing Dong, Pei-Ge Wang
World Journal of Gastrointestinal Surgery.2023; 15(10): 2320. CrossRef
Patient Outcomes Related to In-Hospital Delays in Appendicectomy for Appendicitis: A Retrospective Study
Oliver Claydon, Billy Down, Sidharth Kumar
Cureus.2022;[Epub] CrossRef
Possibility for avoidance of urgent nighttime operations for acute appendicitis in a regional core university hospital
Tomoya Tago, Mitsugi Shimoda, Ryosuke Imazato, Ryutaro Udou, Kenji Katsumata, Akihiko Tsuchida, Shuji Suzuki
Asian Journal of Endoscopic Surgery.2022; 15(1): 22. CrossRef
Daytime versus nighttime laparoscopic appendectomy in term of complications and clinical outcomes: A retrospective study of 1001 appendectomies
Amjad A. Shah, Raed M. Al-Zoubi, Ahmad R. Al-Qudimat, Mohamed Amine Rejeb, Laxmi Kumari Ojha, Sharif Abdulzem, Khadija Qadir, Sara Sameer, Ahmad Zarour, Mohamed Said Ghali
Heliyon.2022; 8(12): e11911. CrossRef
Nighttime Appendectomy is Safe and has Similar Outcomes as Daytime Appendectomy: A Study of 1198 Appendectomies
T. Mönttinen, H. Kangaspunta, J. Laukkarinen, M. Ukkonen
Scandinavian Journal of Surgery.2021; 110(2): 227. CrossRef
Revisiting delayed appendectomy in patients with acute appendicitis
Jian Li
World Journal of Clinical Cases.2021; 9(20): 5372. CrossRef
Laparoscopic Appendectomy in the Days of COVID-19
Roi Abramov, Mariya Neymark, Asaf Harbi, Hayim Gilshtein
Surgical Laparoscopy, Endoscopy & Percutaneous Techniques.2021; 31(5): 599. CrossRef
Did the COVID-19 Pandemic Prolong the Time Till Diagnosis and Worsen Outcomes for Children with Acute Appendicitis?
Idilė Vansevičienė, Danielė Bučinskaitė, Dalius Malcius, Aušra Lukošiūtė-Urbonienė, Mindaugas Beržanskis, Emilis Čekanauskas, Vidmantas Barauskas
Medicina.2021; 57(11): 1234. CrossRef
Factors influencing surgical management of acute appendicitis in a large university hospital without a dedicated emergency theatre
Megan Power Foley, Michael MacLean, Ciaran Doyle, Timothy Nugent, Michael E. Kelly, Fady Narouz, Brian Mehigan, Paul McCormick, John Larkin
Irish Journal of Medical Science (1971 -).2020; 189(2): 649. CrossRef
Invited commentary on “Short-term outcome after appendectomy is related to preoperative delay but not to the time of day of the procedure: A nationwide retrospective cohort study of 9224 patients”
Xuan Liang, Yanxia Sun
International Journal of Surgery.2020; 79: 140. CrossRef
Quality Outcomes in Appendicitis Care: Identifying Opportunities to Improve Care
Syed Mohammad Umar Kabir, Magda Bucholc, Carol-Ann Walker, Opeyemi O. Sogaolu, Saqib Zeeshan, Michael Sugrue
Life.2020; 10(12): 358. CrossRef
Effect of Delay to Operation on Outcomes in Patients with Acute Appendicitis: a Systematic Review and Meta-analysis
Jian Li, Run Xu, Deng-Min Hu, Yao Zhang, Tu-Ping Gong, Xue-Lian Wu
Journal of Gastrointestinal Surgery.2019; 23(1): 210. CrossRef
Is postponed laparoscopic appendectomy justified for patients with acute appendicitis?
Atsushi Kohga, Kiyoshige Yajima, Takuya Okumura, Kimihiro Yamashita, Jun Isogaki, Kenji Suzuki, Katsuaki Muramatsu, Akira Komiyama, Akihiro Kawabe
Asian Journal of Endoscopic Surgery.2019; 12(4): 423. CrossRef
Is early appendectomy in adults diagnosed with acute appendicitis mandatory? A prospective study
Salma Abu Foul, Ella Egozi, Ahmad Assalia, Yoram Kluger, Ahmad Mahajna
World Journal of Emergency Surgery.2019;[Epub] CrossRef
Preoperative Clinical Factors Associated with Short‐Stay Laparoscopic Appendectomy
Aurélie Vuagniaux, Olivier Gié, Fabio Butti, Pedro Manuel Marques‐Vidal, Nicolas Demartines, Styliani Mantziari
World Journal of Surgery.2019; 43(11): 2771. CrossRef

Management Outcomes of Colonoscopic Perforations Are Affected by the General Condition of the Patients: Jae Ho Park, Kyung Jong Kim; Ann Coloproctol. 2018;34(1):16-22. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.16

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Purpose

The management of a colonoscopic perforation (CP) varies from conservative to surgical. The objective of this study was to evaluate the outcomes between surgical and conservative treatment of patients with a CP.

Methods

From 2003 to 2016, the medical records of patients with CP were retrospectively reviewed. Patients were divided into 2 groups depending on whether they initially received conservative or surgical treatment.

Results

During the study period, a total of 48 patients with a CP were treated. Among them, 5 patients had underlying colorectal cancer and underwent emergency radical cancer surgery; these patients were excluded. The mean age of the remaining 43 patients was 64.5 years old, and the most common perforation site was the sigmoid colon (15 patients). The initial conservative care group included 16 patients, and the surgery group included 27 patients. In the conservative group, 5 patients required conversion to surgery (failure rate: 5 of 16 [31.3%]). Of the surgery group, laparoscopic surgery was performed on 19 patients and open surgery on 8 patients, including 2 conversion cases. Major postoperative complications developed in 11 patients (34.4%), and postoperative mortality developed in 4 patients (12.5%). The only predictor for poor prognosis after surgery was a high American Society of Anesthesiologists physical status classification.

Conclusion

In this study, conservative treatment for patients with a CP had a relatively high failure rate. Furthermore, surgical treatment showed significant rates of complications and mortality, which depended on the general status of the patients.

Citations

Citations to this article as recorded by

Multicenter retrospective evaluation of ileocecocolic perforations associated with diagnostic lower gastrointestinal endoscopy in dogs and cats
Vanessa L. Woolhead, Jacqueline C. Whittemore, Sarah A. Stewart
Journal of Veterinary Internal Medicine.2020; 34(2): 684. CrossRef

Predictive Factors Affecting the Clinical Course of Patients With Diverticulitis: Who Needs Hospital Management?: Taeyoung Yoo, Keun Ho Yang, Jungbin Kim, Inseok Park, Hyunjin Cho, Geumhee Gwak, Byung Noe Bae, Ki Hwan Kim; Ann Coloproctol. 2018;34(1):23-28. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.23

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Abstract PDF

Purpose

The aim of this study is to determine the predictable factors that affect the clinical course, especially the hospital stay, the operation performed, and to determine factors that will be helpful in deciding whether in-hospital or outpatient treatment is appropriate.

Methods

We retrospectively collected medical data for patients who had been diagnosed with acute diverticulitis at Inje University Sanggye Paik Hospital between January and December 2016. In total, 117 patients were enrolled in this study. We examined clinical factors, including age, sex, body mass index, pain, body temperature, white blood cell count, C-reactive protein, nil per os (NPO) time, hospital duration, computed tomography (CT) findings, location of diverticulitis, operation performed, and presence of comorbidity (e.g., hypertension and diabetes mellitus).

Results

In the multivariate analysis, the statistically significant factor related with hospital duration was the presence of perforation on the CT scan (P < 0.001). Longer NPO time was related with pain score (>7) (P = 0.011). Operations were mainly performed in patients with left-sided colonic diverticulitis (P = 0.012).

Conclusion

We suggest a perforation finding on the CT scan, a severe pain score at least above 7 on a numeric rating pain scale, and a left-sided lesion are absolute indications for in-hospital management.

Citations

Citations to this article as recorded by

Epidemiology, Management, and Outcomes of Acute Diverticulitis in King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia
Hanan M Bamanie, Nadim Malibary, Nada A Algarni, Jumana O Badawi, Lujain M AlNasser, Khadijah A Almalki, Renad F Alnemari
Cureus.2022;[Epub] CrossRef
Development of a prediction model for clinically important outcomes of acute diverticulitis
Stephen Gyung Won Lee, Sang Do Shin, Hui Jai Lee, Gil Joon Suh, Do Joong Park
The American Journal of Emergency Medicine.2021; 50: 27. CrossRef
Diverticulitis: An Update From the Age Old Paradigm
Alexander T. Hawkins, Paul E. Wise, Tiffany Chan, Janet T. Lee, Tamara Glyn, Verity Wood, Timothy Eglinton, Frank Frizelle, Adil Khan, Jason Hall, M.I. Mohammed Ilyas, Maria Michailidou, Valentine N. Nfonsam, Michelle L. Cowan, Jennifer Williams, Scott R.
Current Problems in Surgery.2020; 57(10): 100862. CrossRef
Is the outpatient management of acute diverticulitis safe and effective? A systematic review and meta-analysis
R. Cirocchi, J. J. Randolph, G. A. Binda, S. Gioia, B. M. Henry, K. A. Tomaszewski, M. Allegritti, A. Arezzo, R. Marzaioli, P. Ruscelli
Techniques in Coloproctology.2019; 23(2): 87. CrossRef
Clinical presentation and outcomes of acute diverticulitis in a Middle Eastern population
Jasim Alabbad, Fawaz Abdul Raheem, Saba Al-Saddah, Abdulaziz Al-Mubarak
Arab Journal of Gastroenterology.2019; 20(2): 99. CrossRef

Transanal Endoscopic and Transabdominal Robotic Total Mesorectal Excision for Mid-to-Low Rectal Cancer: Comparison of Short-term Postoperative and Oncologic Outcomes by Using a Case-Matched Analysis: Ki Young Lee, Jung Kyoung Shin, Yoon Ah Park, Seong Hyeon Yun, Jung Wook Huh, Yong Beom Cho, Hee Cheol Kim, Woo Yong Lee; Ann Coloproctol. 2018;34(1):29-35. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.29

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Abstract PDF

Purpose

This study aimed to compare short-term postoperative and oncologic outcomes of a transanal endoscopic total mesorectal excision (TME) to those of a transabdominal robotic TME.

Methods

A total of 62 patients with rectal cancer underwent transanal (n = 26) or robotic (n = 36) TME between June 2013 and December 2014. After case-matching by tumor location and TNM stage, 45 patients were included for analysis. The median follow-up period was 21.3 months. Operative, histopathologic and postoperative outcomes and recurrences were analyzed.

Results

Patients younger than 60 years of age were more frequently observed in the robotic TME group (75.0% vs. 47.6%, P = 0.059), but tumor location, cT and cN category, and preoperative chemoradiotherapy were not different between the 2 groups. Estimated blood loss was greater in the transanal group (283 mL vs. 155 mL, P = 0.061); however, the operation time and the rate of a diverting ileostomy and subsequent ileostomy repair were not different between the groups. The proximal resection margin was longer in the transanal TME group (20.8 cm ± 16.0 cm, P = 0.030), but the distal resection margins, involvements of the circumferential resection margin, TME quality, numbers of retrieved lymph nodes, postoperative complications, including anastomotic leak and voiding difficulty, and recurrence rates for the 2 groups were not statistically different.

Conclusion

Transanal endoscopic and transabdominal robotic TME showed similar histopathologic and postoperative outcomes with the exception of the estimated blood loss and the proximal resection margin for a select group of patients.

Citations

Citations to this article as recorded by

Peri-operative, oncological and functional outcomes of robotic versus transanal total mesorectal excision in patients with rectal cancer: A systematic review and meta-analysis
A. Y. Y. Mohamedahmed, S. Zaman, A. A. Wuheb, A. Ismail, M. Nnaji, A. A. Alyamani, H. A. Eltyeb, N. A. Yassin
Techniques in Coloproctology.2024;[Epub] CrossRef
Systematic review and meta-analysis comparing robotic total mesorectal excision versus transanal total mesorectal excision for rectal cancer
Mohamed Ali Chaouch, Mohammad Iqbal Hussain, Maissa Jellali, Amine Gouader, Alessandro Mazzotta, Adriano Carneiro da Costa, Bassem Krimi, Jim Khan, Hani Oweira
Scandinavian Journal of Surgery.2024;[Epub] CrossRef
A systematic review and meta-analysis of minimally invasive total mesorectal excision versus transanal total mesorectal excision for mid and low rectal cancer
Du Yong Gang, Lin Dong, Zhang DeChun, Zhang Yichi, Lu Ya
Frontiers in Oncology.2023;[Epub] CrossRef
Robotic-assisted laparoscopic low anterior resection versus trans-anal total mesorectal excision for malignant rectal lesion: a prospective cohort trial
Ahmed F.A. Farag, Ahmed M.A. Mahmoud, Haitham M. Azmy, Abdrabbou N. Mashhour, Ahmed S. Khalifa, Yasser Debakey, Mohamed Y. Elbarmelgi
The Egyptian Journal of Surgery.2023; 42(4): 859. CrossRef
Robotic or transanal total mesorectal excision (TaTME) approach for rectal cancer, how about both? Feasibility and outcomes from a single institution
Yusuke Inoue, Jing Yu Ng, Chun-Ho Chu, Yi-Ling Lai, I.-Ping Huang, Shung-Haur Yang, Chien-Chih Chen
Journal of Robotic Surgery.2022; 16(1): 149. CrossRef
Long-term oncologic outcomes of transanal TME compared with transabdominal TME for rectal cancer: a systematic review and meta-analysis
Jae Young Moon, Min Ro Lee, Gi Won Ha
Surgical Endoscopy.2022; 36(5): 3122. CrossRef
Multidisciplinary treatment strategy for early rectal cancer
Gyung Mo Son, In Young Lee, Sung Hwan Cho, Byung-Soo Park, Hyun Sung Kim, Su Bum Park, Hyung Wook Kim, Sang Bo Oh, Tae Un Kim, Dong Hoon Shin
Precision and Future Medicine.2022; 6(1): 32. CrossRef
Comparison of transanal total mesorectal excision and robotic total mesorectal excision for low rectal cancer after neoadjuvant chemoradiotherapy
Jung Kyong Shin, Hee Cheol Kim, Seong Hyeon Yun, Yoon Ah Park, Yong Beom Cho, Jung Wook Huh, Woo Yong Lee
Surgical Endoscopy.2021; 35(12): 6998. CrossRef
Statistical, Clinical, Methodological Evaluation of Local Recurrence Following Transanal Total Mesorectal Excision for Rectal Cancer: A Systematic Review
Hans H. Wasmuth, Mahir Gachabayov, Les Bokey, Abe Fingerhut, Guy R. Orangio, Feza H. Remzi, Roberto Bergamaschi
Diseases of the Colon & Rectum.2021; 64(7): 899. CrossRef
A nationwide comparison of short‐term outcomes after transanal, open, laparoscopic, and robot‐assisted total mesorectal excision
Ilze Ose, Sharaf Karim Perdawood
Colorectal Disease.2021; 23(10): 2671. CrossRef
Robotic total mesorectal excision or transanal total mesorectal excision meta‐analysis
Michelle Zhiyun Chen, Yeng Kwang Tay, Satish K. Warrier, Alexander G. Heriot, Joseph C. Kong
ANZ Journal of Surgery.2021; 91(11): 2269. CrossRef
A systematic review and meta-analysis of robotic-assisted transabdominal total mesorectal excision and transanal total mesorectal excision: which approach offers optimal short-term outcomes for mid-to-low rectal adenocarcinoma?
J. W. Butterworth, W. A. Butterworth, J. Meyer, C. Giacobino, N. Buchs, F. Ris, R. Scarpinata
Techniques in Coloproctology.2021; 25(11): 1183. CrossRef
Outcomes of robotic low anterior resection versus transanal total mesorectal excision for rectal cancer
J L B Buan, W Z So, X C Lim, C S Chong
BJS Open.2021;[Epub] CrossRef
Initial Experience of Robotic Total Mesorectal Excision for Rectal Cancer
Jung Kyong Shin, Jung Wook Huh
Annals of Robotic and Innovative Surgery.2020; 1(1): 33. CrossRef
Robotic Total Mesorectal Excision for Rectal Cancer: Current Evidences and Future Perspectives
Je-Ho Jang, Chang-Nam Kim
Annals of Coloproctology.2020; 36(5): 293. CrossRef
Systemic review and network meta‐analysis comparing minimal surgical techniques for rectal cancer: quality of total mesorectum excision, pathological, surgical, and oncological outcomes
Emanuele Rausa, Federica Bianco, Michael E. Kelly, Alberto Aiolfi, Fausto Petrelli, Gianluca Bonitta, Giovanni Sgroi
Journal of Surgical Oncology.2019; 119(7): 987. CrossRef
Does transanal total mesorectal excision of rectal cancer improve histopathology metrics and/or complication rates? A meta-analysis
Mahir Gachabayov, Inna Tulina, Roberto Bergamaschi, Petr Tsarkov
Surgical Oncology.2019; 30: 47. CrossRef
Transanal Total Mesorectal Excision for Rectal Cancer: Perioperative and Oncological Outcomes
Hyuk Hur
Annals of Coloproctology.2018; 34(1): 1. CrossRef
Evolution of surgery for rectal cancer: Transanal total mesorectal excision~new standard or fad?~
Hirotoshi Hasegawa, Koji Okabayashi, Masashi Tsuruta, Takashi Ishida, Fumitaka Asahara, Mark G Coleman
Journal of the Anus, Rectum and Colon.2018; 2(4): 115. CrossRef

Efficacy and Safety of Ramosetron Injection for Nausea and Vomiting in Colorectal-Cancer Patients Undergoing a Laparoscopic Colectomy: A Randomized, Double-Blind, Comparative Study: Han Eol Park, Min Ki Kim, Won-Kyung Kang; Ann Coloproctol. 2018;34(1):36-41. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.36

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Abstract PDF

Purpose

A laparoscopic colectomy in colorectal-cancer patients is usually associated with a high risk of postoperative nausea and vomiting (PONV). The purpose of this study is to evaluate the efficacy of injection of long-acting 5-hydroxytryptamine type 3 (5-HT₃) receptor antagonist for the reduction of PONV in patients with colorectal cancer.

Methods

A total of 48 patients scheduled to undergo a laparoscopic colectomy for colorectal cancer were randomized in a double-blinded fashion. Patients were randomly allocated to 1 of 2 groups and assigned to receive either 0.3 mg of ramosetron intravenously (group A, n = 25) or 2 mL of normal saline (placebo) (group B, n = 22) immediately after the operation. The incidence of PONV, the nausea severity scale score, the visual analogue scale (VAS) score for pain, the total amount of patient-controlled analgesia used, the recovery of bowel function, and morbidities were assessed at 1 hour and at 24, 48, and 72 hours after surgery.

Results

The baseline and the operative characteristics were similar between the groups (P > 0.05). The number of cases without PONV (complete response) was higher for group A (ramosetron) than group B (normal saline): 24 hours after surgery, 92.0% (23 of 25) for group A versus 54.5% (12 of 22) for group B; 48 hours after surgery, 92% (23 of 25) for group A versus 81.8% (18 of 22) for group B (both P < 0.05). No serious adverse events occurred.

Conclusion

Postoperative ramosetron injection is effective for the prevention of PONV after a laparoscopic colectomy in colorectal-cancer patients.

Citations

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Postoperative ileus after digestive surgery: Network meta‐analysis of pharmacological intervention
Etienne Buscail, Thibault Planchamp, Guillaume Le Cosquer, Manon Bouchet, Julie Thevenin, Nicolas Carrere, Fabrice Muscari, Olivier Abbo, Charlotte Maulat, Ariane Weyl, Jean Pierre Duffas, Antoine Philis, Laurent Ghouti, Cindy Canivet, Jean Paul Motta, Na
British Journal of Clinical Pharmacology.2024; 90(1): 107. CrossRef
A Clinical Risk Analysis of Postoperative Nausea and Vomiting After Colorectal Cancer Surgery
Masatsugu Hiraki, Toshiya Tanaka, Mika Koga, Daisuke Miura, Eiji Sadashima, Hirofumi Sato, Shinji Mitsumizo, Kenji Kitahara
Journal of Coloproctology.2022; 42(03): 203. CrossRef
Comparing the effects of continuous infusion of esmolol and ramosetron alone and in combination on nausea and vomiting after laparoscopic cholecystectomy: A prospective, randomized, double-blind study
Jae Young Ji, Nan Seol Kim, Yong Han Seo, Ho Soon Jung, Hea Rim Chun, Jin Soo Park, Jeong Soo Choi, Jae Min Ahn, Woo Jong Kim
Medicine.2022; 101(35): e30105. CrossRef
Levosulpiride and Ramosetron for the Prevention of Postoperative Nausea and Vomiting in Laparoscopic Surgery
R. T. Ranjithkumar, Imran Sholapur, Ravi Bhat, C. Chandan Kumar
Anesthesia Essays & Researches.2022; 16(3): 307. CrossRef
Reducing ileus after colorectal surgery: A network meta-analysis of therapeutic interventions
James Ashcroft, Aminder Anthony Singh, Bhavna Ramachandran, Amir Habeeb, Victoria Hudson, Jeremy Meyer, Constantinos Simillis, Richard Justin Davies
Clinical Nutrition.2021; 40(7): 4772. CrossRef
Management strategies for the treatment and prevention of postoperative/postdischarge nausea and vomiting: an updated review
Ofelia Loani Elvir-Lazo, Paul F. White, Roya Yumul, Hillenn Cruz Eng
F1000Research.2020; 9: 983. CrossRef
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis
Stephanie Weibel, Gerta Rücker, Leopold HJ Eberhart, Nathan L Pace, Hannah M Hartl, Olivia L Jordan, Debora Mayer, Manuel Riemer, Maximilian S Schaefer, Diana Raj, Insa Backhaus, Antonia Helf, Tobias Schlesinger, Peter Kienbaum, Peter Kranke
Cochrane Database of Systematic Reviews.2020;[Epub] CrossRef
Postoperative nausea and vomiting in patients undergoing colorectal surgery within an institutional enhanced recovery after surgery protocol: comparison of two prophylactic antiemetic regimens
Jennifer Holder-Murray, Stephen A Esper, Michael L Boisen, Julie Gealey, Katie Meister, David S Medich, Kathirvel Subramaniam
Korean Journal of Anesthesiology.2019; 72(4): 344. CrossRef

Distribution of Lymph Nodes in Stage III Patients With Mid and Low Rectal Cancer: Preliminary Study: Sohyun Kim; Ann Coloproctol. 2018;34(1):42-46. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.42

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Abstract PDF

Purpose

Most patients with rectal cancer undergo a total mesorectal excision and a partial resection of the sigmoid colon to improve oncologic outcomes. The aim of this study was to assess the distribution of lymph nodes (LNs) in rectal cancer.

Methods

The records of 54 patients with mid and low rectal cancer between April 2015 and March 2017 were reviewed, and 49 patients were enrolled in this study. All harvested LNs were analyzed according to the harvested area: the mesorectum area (MA), the vascular pedicle area (VA), and the sigmoid area (SA).

Results

Finally, 865 LNs were harvested from all patients, and of these, 71 (8.2%) showed metastases. In stage III patients, 343 LNs were harvested, and of these, 52 (15.2%) showed metastases. Significant differences were found in the total numbers of harvested LNs by area (P < 0.001) and in the numbers of harvested positive LNs by area (P < 0.001). In stage III patients, LNs from the MA were more frequently to be positive than were those from the VA (P < 0.001) or the SA (P < 0.001).

Conclusion

LN metastasis in the SA was rare. Therefore, resecting the mesorectum and the vascular pedicle may be more important than resecting the sigmoid mesentery due to concerns about LN metastases.

Citations

Citations to this article as recorded by

Lateral Pelvic Lymph Node Dissection After Neoadjuvant Chemoradiotherapy in Patients With Rectal Cancer: A Single-Center Experience and Literature Review
Min Chul Kim, Jae Hwan Oh
Annals of Coloproctology.2021; 37(6): 382. CrossRef

Case Reports

Endoscopic Band Ligation to Treat a Massive Hemorrhoidal Hemorrhage Following a Transrectal Ultrasound-Guided Prostate Biopsy: Nadim Mahmud, Kirk J. Wangensteen; Ann Coloproctol. 2018;34(1):47-51. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.47

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Prostate cancer is commonly diagnosed by using a transrectal ultrasound (TRUS)-guided biopsy. Although this procedure is usually well tolerated, rarely it may be complicated by massive rectal bleeding. We report a case of a 77-year-old male who underwent a TRUS biopsy and subsequently developed recurrent episodes of rectal bleeding with syncope and anemia requiring the transfusion of multiple units of blood. A sigmoidoscopy revealed the source of the bleeding: a large hemorrhoid on the anterior wall of the rectum with an overlying ulceration. We successfully applied a band to ligate the hemorrhoid, and the patient's condition improved. To our knowledge, this case represents the first report of a successful band ligation to treat massive bleeding from a hemorrhoid that had been punctured in the course of the TRUS biopsy procedure.

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Endoscopic Therapy in the Management of Patients With Severe Rectal Bleeding Following Transrectal Ultrasound-Guided Prostate Biopsy: A Case-Based Systematic Review
Adnan Malik, Rizwan Ishtiaq, Muhammad Hassan Naeem Goraya, Faisal Inayat, Vinaya V. Gaduputi
Journal of Investigative Medicine High Impact Case Reports.2021; 9: 232470962110132. CrossRef

Rhabdomyolysis Following Colonoscopy: A Case Report: Jin Yong Jeong, Kap Tae Kim, Mi Jin Kim, Yea Jeong Kim; Ann Coloproctol. 2018;34(1):52-55. Published online February 28, 2018; DOI: https://doi.org/10.3393/ac.2018.34.1.52

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We experienced a case of 1 patient who died from rhabdomyolysis-related complications after colonoscopy. A 60-year-old man had undergone an ‘uncomplicated’ colonoscopic polypectomy. Approximately 10 hours following this procedure, the patient complained of increasing left abdominal pain. His computed tomography image showed free gas, but his operative findings revealed no macroscopic perforation or abscess formation. Eight hours after the operation, the patient presented with myoglobulinuria, and we diagnosed the condition to be rhabdomyolysis. Based on this case, we recommend that rhabdomyolysis be added to the list of complications following a colonoscopic procedure. Moreover, for prevention and early treatment, endoscopists should be attentive to the risk factors and signs/symptoms of rhabdomyolysis.

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Rhabdomyolysis following colorectal endoscopic submucosal dissection: A case report
Ying Chen, Wenxuan Zhang, Junqiang Cai, Min Zhong
Clinical Case Reports.2024;[Epub] CrossRef

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