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Volume 35(6); December 2019
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Editorials
Usefulness of Patient-Reported Outcome Measures and Anorectal Physiologic Tests in Predicting Clinical Outcome for Fecal Incontinence
Chang-Nam Kim
Ann Coloproctol. 2019;35(6):289-290.   Published online December 31, 2019
DOI: https://doi.org/10.3393/ac.2019.11.20
  • 2,894 View
  • 54 Download
  • 2 Web of Science
  • 2 Citations
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  • A systematic review of translation and experimental studies on internal anal sphincter for fecal incontinence
    Minsung Kim, Bo-Young Oh, Ji-Seon Lee, Dogeon Yoon, Wook Chun, Il Tae Son
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Laterality: Immunological Differences Between Right-Sided and Left-Sided Colon Cancer
Seong Kyu Baek
Ann Coloproctol. 2019;35(6):291-293.   Published online December 31, 2019
DOI: https://doi.org/10.3393/ac.2019.11.11
  • 3,396 View
  • 124 Download
  • 3 Web of Science
  • 3 Citations
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  • Clinicopathological significance and prognostic role of LAG3 + tumor-infiltrating lymphocytes in colorectal cancer; relationship with sidedness
    Shirin Tavana, Zahra Mokhtari, Mohammad Hossein Sanei, Zahra Heidari, Amir-Reza Dehghanian, Zahra Faghih, Marzieh Rezaei
    Cancer Cell International.2023;[Epub]     CrossRef
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    Juliano Oliveira-Silveira, Eduardo Filippi-Chiela, Jenifer Saffi
    Scientific Reports.2023;[Epub]     CrossRef
  • Comparative analysis of clonal evolution among patients with right- and left-sided colon and rectal cancer
    Santasree Banerjee, Xianxiang Zhang, Shan Kuang, Jigang Wang, Lei Li, Guangyi Fan, Yonglun Luo, Shuai Sun, Peng Han, Qingyao Wu, Shujian Yang, Xiaobin Ji, Yong Li, Li Deng, Xiaofen Tian, Zhiwei Wang, Yue Zhang, Kui Wu, Shida Zhu, Lars Bolund, Huanming Yan
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Review
A Review of the Role of Carcinoembryonic Antigen in Clinical Practice
Claire Hall, Louise Clarke, Atanu Pal, Pamela Buchwald, Tim Eglinton, Chris Wakeman, Frank Frizelle
Ann Coloproctol. 2019;35(6):294-305.   Published online December 31, 2019
DOI: https://doi.org/10.3393/ac.2019.11.13
  • 11,915 View
  • 402 Download
  • 105 Web of Science
  • 100 Citations
AbstractAbstract PDF
Carcinoembryonic antigen (CEA) is not normally produced in significant quantities after birth but is elevated in colorectal cancer. The aim of this review was to define the current role of CEA and how best to investigate patients with elevated CEA levels. A systematic review of CEA was performed, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies were identified from PubMed, Cochrane library, and controlled trials registers. We identified 2,712 papers of which 34 were relevant. Analysis of these papers found higher preoperative CEA levels were associated with advanced or metastatic disease and thus poorer prognosis. Postoperatively, failure of CEA to return to normal was found to be indicative of residual or recurrent disease. However, measurement of CEA levels alone was not sufficient to improve survival rates. Two algorithms are proposed to guide investigation of patients with elevated CEA: one for patients with elevated CEA after CRC resection, and another for patients with de novo elevated CEA. CEA measurement has an important role in the investigation, management and follow-up of patients with colorectal cancer.

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Original Articles
Role of a Micronized Purified Flavonoid Fraction as an Adjuvant Treatment to Rubber Band Ligation for the Treatment of Patients With Hemorrhoidal Disease: A Longitudinal Cohort Study
Ana Célia Caetano, Catarina Cunha, Bruno Arroja, Dalila Costa, Carla Rolanda
Ann Coloproctol. 2019;35(6):306-312.   Published online December 31, 2019
DOI: https://doi.org/10.3393/ac.2018.09.18
  • 3,810 View
  • 153 Download
  • 3 Web of Science
  • 5 Citations
AbstractAbstract PDF
Purpose
Nonsurgical treatment of hemorrhoidal disease (HD) includes medical and instrumental techniques. We aimed to compare the efficacy of the most frequently used nonsurgical strategies, either alone or in combination, applied in an ambulatory setting.
Methods
Patients who received nonsurgical treatment for HD by proctology appointment at the Gastroenterology Department of Braga Hospital were evaluated. Isolated rubber band ligation (RBL) and a combination of RBL with a micronized purified flavonoid fraction (MPFF) were the 2 most frequently used strategies. Symptoms of HD (bleeding, pruritus, pain at rest, pain at defecation and prolapse) were assessed at days 0, 7, and 28 by using a severity grading scale (0 to 4/5). A Global Symptom score was constructed to assess the overall severity and compare the overall improvements of the HD symptoms between the 2 most frequently used strategies.
Results
Nineteen patients underwent the combined treatment (RBL + MPFF group) and 25 the RBL treatment (RBL group). A comparison of the 2 treatment groups showed significant improvements in the combined treatment group in terms of bleeding at days 7 (P = 0.001) and 28 (P = 0.002) and in the pruritus intensity during the first week (P < 0.001). A trend toward clinical benefit was also verified in the combined treatment group for all other HD symptoms (pain at rest, pain at defecation and prolapse).
Conclusion
A combined treatment approach with MPFF and RBL significantly reduced the intensity of bleeding during the first month and the pruritus during the first week.

Citations

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    SS Singh, MA Strydom, M Balmith, C Megaw, MJ Nell
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    Polish Journal of Surgery.2024; 96(3): 1.     CrossRef
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    Chun-Ying Qu, Fei-Yu Zhang, Wen Wang, Feng-Yu Gao, Wu-Lian Lin, Hao Zhang, Guang-Yu Chen, Yi Zhang, Ming-Ming Li, Zheng-Hong Li, Mei-Hong Cai, Lei-Ming Xu, Feng Shen
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    Sara Razdar, Yunes Panahi, Ramtin Mohammadi, Leila Khedmat, Hossein Khedmat
    BMJ Open Gastroenterology.2023; 10(1): e001158.     CrossRef
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    D. D. Shlyk, I. A. Tulina, P. V. Tsarkov
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Comparison of Limberg Flap and Karydakis Flap Surgery for the Treatment of Patients With Pilonidal Sinus Disease: A Single-Blinded Parallel Randomized Study
Mina Alvandipour, Mohammad Sadegh Zamani, Mojtaba Ghorbani, Jamshid Yazdani Charati, Mohammad Yasin Karami
Ann Coloproctol. 2019;35(6):313-318.   Published online May 22, 2019
DOI: https://doi.org/10.3393/ac.2018.09.27
  • 13,967 View
  • 226 Download
  • 11 Web of Science
  • 18 Citations
AbstractAbstract PDF
Purpose
Pilonidal sinus disease is a common condition, which mostly affects young men. While various surgical techniques have been introduced for treating intergluteal pilonidal disease (IPD), controversies still exist regarding the best surgical approach. The purpose of this study was to compare the efficiency and the short-term outcomes of Limberg flap and Karydakis flap surgeries for the treatments of patients with IPD.
Methods
A total of 80 patients with IPD who had underwent either Karydakis flap (KF group: n = 37) or Limberg flap (LF group: n = 27) surgery between January 2015 and January 2016 at Imam Khomeini Hospital of Sari in the North of Iran were recruited for inclusion in this randomized, single-blind study.
Results
Compared to the KF group, the LF group showed faster complete wound healing, longer duration of surgery and hospital stay, larger wound size, and shorter period of incapacity for work. The overall patient satisfaction in the LF group was significantly higher than that in the KF group. The visual analogue scale score of pain was lower in the LF group than in the KF group. Also, the overall frequency of postoperative complications was higher in the KF group than in the LF group. Recurrence was reported in one patient from the KF group.
Conclusion
Given the lower rate of postoperative complications and greater cosmetic satisfaction of patients, the Limberg flap procedure should be selected, instead of the Karydakis flap procedure, as the standard technique for treating patients with IPD.

Citations

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  • Midline and off-midline wound closure methods after surgical treatment for pilonidal sinus
    Zhaolun Cai, Zhou Zhao, Qin Ma, Chaoyong Shen, Zhiyuan Jiang, Chunyu Liu, Chunjuan Liu, Bo Zhang
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    E. N. Shubrov, A G. Baryshev, K. V. Triandafilov
    Koloproktologia.2024; 23(1): 129.     CrossRef
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    Wei Lu, Shujuan Huang, Hui Ye, Shang Xiang, Xiangsheng Zeng
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    Norah E. Liang, Claire Abrajano, Kyla Santos Dalusag, Bill Chiu
    Pediatric Surgery International.2024;[Epub]     CrossRef
  • The application of the Limberg flap repair technique in the surgical treatment of pilonidal sinus disease
    Yaoyao Song, Yu Zang, Zequn Chen, Jianjun Li, Minhui Zhu, Hongjuan Zhu, Wanli Chu, Gang Liu, Chuan'an Shen
    International Wound Journal.2023; 20(6): 2241.     CrossRef
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    Lindsay A. Gil, Katherine J. Deans, Peter C. Minneci
    JAMA Surgery.2023; 158(8): 875.     CrossRef
  • Bilaterally parallel elliptic flap versus Karydakis flap in primary pilonidal sinus disease: a randomized controlled trial
    Umut Fırat Turan, Serdar Coban, Tezcan Akin, Huseyin Berkem, Bulent Cavit Yuksel, Sadettin Er
    International Journal of Colorectal Disease.2023;[Epub]     CrossRef
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    Burak UÇANER, Şebnem ÇİMEN, Mehmet Zeki BULDANLI
    Journal of Medicine and Palliative Care.2023; 4(6): 694.     CrossRef
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    Dakshay A. Chordia, A. P. Prem, Jameel Akhter, M. Muralidharan, A. Sathishkumar
    Indian Journal of Colo-Rectal Surgery.2023; 6(1): 4.     CrossRef
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    Amr Abdel Hameed Elhiny, Doaa Ali Saad, Mohamed Sadek Farahat
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    Nizamettin KUTLUER, Nurullah AKSOY
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Anorectal Manometry Versus Patient-Reported Outcome Measures as a Predictor of Maximal Treatment for Fecal Incontinence
Lisa Ramage, Shengyang Qiu, Zhu Yeap, Constantinos Simillis, Christos Kontovounisios, Paris Tekkis, Emile Tan
Ann Coloproctol. 2019;35(6):319-326.   Published online December 31, 2019
DOI: https://doi.org/10.3393/ac.2018.10.16
  • 3,286 View
  • 64 Download
  • 4 Web of Science
  • 6 Citations
AbstractAbstract PDF
Purpose
This study aims to establish the ability of patient-reported outcome measures (PROMs) and anorectal manometry (ARM) in predicting the need for surgery in patients with fecal incontinence (FI).
Methods
Between 2008 and 2015, PROMs data, including the Birmingham Bowel and Urinary Symptoms Questionnaire (BBUSQ), Short Form 36 (SF-36), Wexner Incontinence Score and ARM results, were prospectively collected from 276 patients presenting with FI. Spearman rank was used to assess correlations between specific PROMs questions and ARM assessments of sphincter motor function. Binomial regression analyses were performed to identify factors predictive of the need for surgery. Finally, receiver operating characteristic (ROC) curve analyses were performed to establish the utility of individual ARM and PROMs variables in predicting the need for surgical intervention in patients with FI.
Results
Two hundred twenty-eight patients (82.60%) were treated conservatively while 48 (17.39%) underwent surgery. On univariate analyses, all 4 domains of the BBUSQ, all 8 domains of the SF-36, and the Wexner Incontinence Score were significant predictors of surgery. Additionally, maximum resting pressure, 5-second squeeze endurance, threshold volume, and urge volume were significant. On ROC curve analyses, the only significant ARM measurement was the 5-second squeeze endurance. PROMs, such as the incontinence domain of the BBUSQ and five of the SF-36 domains, were identified as fair discriminators of the need for surgery.
Conclusion
PROMs are reliable predictors of maximal treatment in patients with FI and can be readily used in primary care to aid surgical referrals and can be applied in hospital settings as an aid to guide surgical treatment decisions.

Citations

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  • Correlation of Digital Rectal Examination and Anorectal Manometry with Patient-Reported Outcomes Among Women with Fecal Incontinence
    Alayne Markland, Mary Ackenbom, Uduak Andy, Ben Carper, Eric Jelovsek, Douglas Luchristt, Shawn Menefee, Rebecca Rogers, Vivian Sung, Donna Mazloomdoost, Maria Gantz
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    Martina Kovari, Jan Stovicek, Jakub Novak, Michaela Havlickova, Sarka Mala, Andrew Busch, Pavel Kolar, Alena Kobesova
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    D.R. Markaryan, A.M. Lukyanov, T.N. Garmanova, M.A. Agapov, V.A. Kubyshkin
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    Eun Jung Park, Seung Hyuk Baik
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    Chang-Nam Kim
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Short-term Outcomes After Upfront Chemotherapy Followed by Curative Surgery in Metastatic Colon Cancer: A Comparison With Upfront Surgery Patients
Myung Hyun Han, Youn Young Park, Shiva Pratap, Yoon Dae Han, Min Soo Cho, Hyuk Hur, Byung Soh Min, Kang Young Lee, Nam Kyu Kim
Ann Coloproctol. 2019;35(6):327-334.   Published online December 31, 2019
DOI: https://doi.org/10.3393/ac.2019.03.04.1
  • 2,818 View
  • 67 Download
  • 2 Web of Science
  • 2 Citations
AbstractAbstract PDF
Purpose
Upfront systemic chemotherapy with target agents has been recommended for patients with stage IV colon cancer. Some with partial response are considered for curative resection. There is high risk of developing postoperative complications following upfront systemic chemotherapy. We aimed to evaluate short-term perioperative outcomes of curative surgery after upfront chemotherapy in comparison with upfront surgery in patients with metastatic colon cancer.
Methods
Between January 2010 and October 2015, 146 patients (80 in the surgery first group, 66 in the upfront chemotherapy group) who underwent surgical resection before or after systemic chemotherapy for metastatic colon cancer were included in the present study. All decisions for treatment were made through a multidisciplinary team. Postoperative clinical outcomes and complications were analyzed to compare the groups.
Results
There was no difference between the 2 groups in terms of postoperative clinical outcomes. Overall complication rates were not different between the groups (surgery first group: 46.3% vs. upfront chemotherapy group: 60.6%; P = 0.084). When classified according to the Clavien-Dindo method, there was no difference between the 2 groups in terms of major complications (grade 3 or more) (surgery first group: 18.9% vs. upfront chemotherapy group: 27.5%; P = 0.374).
Conclusion
There was no significant increase in major postoperative complications in metastatic colon cancer patients who received upfront chemotherapy followed by curative surgery. Careful patient selection and treatment planning are important.

Citations

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  • Impact of preoperative chemotherapy on perioperative morbidity in combined resection of colon cancer and liver metastases
    Joy Z. Done, Angelos Papanikolaou, Miloslawa Stem, Shannon N. Radomski, Sophia Y. Chen, Chady Atallah, Jonathan E. Efron, Bashar Safar
    Journal of Gastrointestinal Surgery.2023; 27(11): 2380.     CrossRef
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    Young Jin Kim, Chang Hyun Kim
    Annals of Coloproctology.2021; 37(6): 425.     CrossRef
Impact of Adjuvant Chemotherapy Completion on Oncologic Outcomes in ypTNMstage 2 Rectal Cancer Patients
Youn Young Park, Kang Young Lee, Nam Kyu Kim, Sat Byol Lee, Ga Ram Kim, Byung Soh Min, Seong-Taek Oh
Ann Coloproctol. 2019;35(6):335-341.   Published online December 31, 2019
DOI: https://doi.org/10.3393/ac.2019.03.10
  • 3,199 View
  • 59 Download
  • 2 Web of Science
  • 2 Citations
AbstractAbstract PDF
Purpose
Adjuvant chemotherapy (aCT) in rectal cancer patients who have undergone curative resection after neoadjuvant chemoradiation (nCRT) is controversial. We aimed to investigate the benefits of using aCT and the clinical impact of completing aCT in ypstage 2 rectal cancer patients.
Methods
We retrospectively reviewed clinicopathological data from patients who had undergone radical resection after nCRT between January 2006 and December 2012. In total, 152 patients with ypT3/4N0M0 rectal cancer were included. Of these patients, 139 initiated aCT, while 13 did not receive aCT (no-aCT). Among those who received aCT, 132 patients completed their planned cycles (aCT-completion) whereas 7 did not (aCT-incompletion). All patients received longcourse chemoradiation; a 5-fluorouracil-based regimen was used for nCRT in most patients. The prognostic factors affecting disease-free survival (DFS) and overall survival (OS) were analyzed.
Results
The median follow-up duration was 41 months. Demographic data did not differ significantly among the 3 groups. In multivariate analysis, open surgery, a tumor size >2 cm, retrieval of <12 lymph nodes, circumferential resection margin (CRM) positivity and aCT incompletion were independent prognostic factors for poor DFS. Old age (≥60 years), open surgery, CRM positivity, aCT incompletion, and lack of aCT initiation compared to aCT completion were independent prognostic factors for poor OS.
Conclusion
In ypstage 2 rectal cancer patients, aCT after nCRT and total mesorectal excision affected both DFS and OS; however, only patients who completed planned aCT exhibited survival benefits. Therefore, improving patients’ compliance with the completion of aCT is desirable.

Citations

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    Thang Tran, Huy Van Nguyen, Hoa Thi Nguyen, Hung Van Nguyen
    Annals of Medicine & Surgery.2023; 85(9): 4234.     CrossRef
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    In Ja Park
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Immunological Differences Between Right-Sided and Left-Sided Colorectal Cancers: A Comparison of Embryologic Midgut and Hindgut
Han Deok Kwak, Jae Kyun Ju
Ann Coloproctol. 2019;35(6):342-346.   Published online December 31, 2019
DOI: https://doi.org/10.3393/ac.2019.03.17.1
  • 3,363 View
  • 92 Download
  • 7 Web of Science
  • 6 Citations
AbstractAbstract PDF
Purpose
There are known differences in embryology, clinical symptoms, incidences, molecular pathways involved, and oncologic outcomes of right-sided and left-sided colorectal cancers. However, immunologic study has only been characterized for healthy adults. The present study was designed to identify differences in immune cell populations in patients with right-sided and left-sided colorectal cancers.
Methods
A total of 35 patients who underwent colorectal resection for cancer between November 2016 and August 2017 at a tertiary teaching hospital were enrolled in this study. Patients were excluded if they had a disease affecting their immune system. Populations of immune cells, including mucosal-associated invariant T (MAIT), gamma delta T, invariant natural killer T, T, natural killer, and B cells, were measured in the peripheral blood and cancer tissues using flow cytometry, and then assessed based on the origin of the colorectal cancer.
Results
Fifteen had right-side and 20 had left-side colorectal cancer. There were no significant differences between the 2 cohorts for patient characteristics including pathologic stage. Peripheral blood from patients with right-side colon cancers contained fewer MAIT (0.87% right-side vs. 1.74% left-side, P = 0.028) and gamma delta T cells (1.10% right-side vs. 3.05% left-side, P = 0.002). Although the group with right-side colorectal cancer had more MAIT cells in cancer tissues (1.71% vs. 1.00%), this difference was not statistically significant.
Conclusion
There is a difference in population sizes of immune cells in blood between patients with right-sided and leftsided colon cancers. The immune cell composition was determined to be distinct based on embryologic origin.

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    Ramón Cantero-Cid, Karla Marina Montalbán-Hernández, Jenny Guevara, Alejandro Pascual-Iglesias, Elisa Pulido, José Carlos Casalvilla, Cristóbal Marcano, Cristina Barragán Serrano, Jaime Valentín, Gloria Cristina Bonel-Pérez, José Avendaño-Ortiz, Verónica
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    Kyung Uk Jung, Hyung Ook Kim, Hungdai Kim
    Journal of the Anus, Rectum and Colon.2022; 6(4): 231.     CrossRef
  • Variants of creating heterotopic and orthotopic PDX models of human colorectal cancer
    A. A. Kiblitskaya, A. Y. Maksimov, A. S. Goncharova, Ye. M. Nepomnyashchaya, Ye. Y. Zlatnik, G. Y. Yegorov, Ye. A. Lukbanova, Ye. V. Zaikina, A. V. Volkova
    Bulletin of Siberian Medicine.2022; 21(3): 50.     CrossRef
  • Genotypic and Phenotypic Characteristics of Hereditary Colorectal Cancer
    Jin Cheon Kim, Walter F. Bodmer
    Annals of Coloproctology.2021; 37(6): 368.     CrossRef
  • Laterality: Immunological Differences Between Right-Sided and Left-Sided Colon Cancer
    Seong Kyu Baek
    Annals of Coloproctology.2019; 35(6): 291.     CrossRef
Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study
Soomin Nam, Yoon Jung Choi, Dong Wook Kim, Eun-Cheol Park, Jung-Gu Kang
Ann Coloproctol. 2019;35(6):347-356.   Published online November 13, 2019
DOI: https://doi.org/10.3393/ac.2019.10.21
  • 4,527 View
  • 131 Download
  • 26 Web of Science
  • 24 Citations
AbstractAbstract PDF
Purpose
The incidence of colorectal cancer in Korea has recently increased, making it the second most common cancer in men and the third most common cancer in women. Risk factors for colorectal cancer have been studied worldwide, but risk factors specific for the Korean population have not been established. In this study, we investigated incidence trends and risk factors of colorectal cancer in Korea.
Methods
A total of 8,846,749 subjects were included. Colorectal cancer incidence was investigated using Korea National Health Insurance Service claim data from 2004 to 2014. Colorectal cancer diagnoses were obtained by evaluating colorectal cancer diagnostic codes and the cancer registry for cost sharing. Risk factor identification for colorectal cancer was obtained from National Health Examination data from 2004 to 2005. Cox proportional hazard model statistical analysis was used to determine risk factors of colorectal cancer.
Results
The incidence of colorectal cancer gradually increased from 2006 to 2014 (from 45.4/100,000 to 54.5/100,000). There was a predominance among men (1.47:1), but incidence trends were similar in both sexes. Old age, high body mass index, and no history of colonoscopy were identified as risk factors in both sexes. High fasting blood glucose, familial history of cancer, frequent alcohol intake, and current smoker were identified as risk factors, especially in men.
Conclusion
The incidence of colorectal cancer has been increasing in Korea. Colonoscopy screening was a protective factor for colorectal cancer, and active use of colonoscopy may reduce incidence. Early diagnosis and care are important, particularly for the high-risk group.

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    Chang Woo Kim, Hyunjin Kim, Hyoung Rae Kim, Daeyeon David Won, Woo Jung Nam, Byung Soh Min, Tae Jeong Oh, Sungwhan An, Suk-Hwan Lee
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    International Journal of Cancer.2022; 150(12): 1958.     CrossRef
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    Kui Seon Park, Young Ki Hong, Yoon Jung Choi, Jung Gu Kang
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    Sanghyun An, Sungjin Park
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  • Low circulating 25-hydroxyvitamin D level is associated with increased colorectal cancer mortality: a systematic review and dose–response meta-analysis
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Case Reports
Pneumatic Colorectal Injury Caused by High Pressure Compressed Air
Jin Young Lee, Young Hoon Sul, Seung Je Go, Jin Bong Ye, Jung Hee Choi
Ann Coloproctol. 2019;35(6):357-360.   Published online May 22, 2019
DOI: https://doi.org/10.3393/ac.2018.08.19
  • 9,345 View
  • 95 Download
  • 3 Web of Science
  • 3 Citations
AbstractAbstract PDF
The pneumatic colorectal injury caused by high pressure compressed air are rare and can be fatal. Herein, we present a case of 45-year-old male who developed sudden onset of severe abdominal pain after cleaning the dust on his pants with high pressure compressed air gun dust cleaner. Emergent exploratory laparotomy was done which findings are a huge rectal perforation with multiple serosal and subserosal tear in sigmoid to splenic flexure of colon. Anterior resection with left hemicolectomy, and temporary transverse colostomy was performed. Postoperative course was uneventful. Recently, prognosis is generally favorable because of prompt diagnosis and emergent surgical management.

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  • Laparoscopic Repair of Colorectal Perforations Induced by Compressed Air Pressure: A Case Report
    Ibrahim Elnogoomi, Hoorieh Qasemi, Mariam Aylan Alshamsi, Majid Alhammadi, Omar Elnogoomi
    Cureus.2024;[Epub]     CrossRef
  • Air Nozzle Injury: Barotrauma Resulted From an Industrial Accident
    Ashok N Mhaske, Nishi Gupta, Abhishek Mishra, Shubham Jaiswal, Chirag Dausage, Jyoti Meena, Gourav Goyal
    Cureus.2024;[Epub]     CrossRef
  • Emergency laparoscopic resection of the anterior rectum due to rectal trauma secondary to compressed air, case report
    Daniel Gómez, Luis F. Cabrera, Mauricio Pedraza, Andres Mendoza-Zuchini, Nicolás Sánchez, Hector W. Cure, Héctor O. Cure Bulicie, Jean A. Pulido
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Hidradenoma Papilliferum of the Anus: A Report of 2 Cases and Review of the Literature
Guh Jung Seo, Ju Heon Seo, Kyung Jin Cho, Hyung-Suk Cho
Ann Coloproctol. 2019;35(6):361-363.   Published online December 31, 2019
DOI: https://doi.org/10.3393/ac.2018.08.03
  • 3,931 View
  • 107 Download
  • 1 Web of Science
  • 2 Citations
AbstractAbstract PDF
Hidradenoma papilliferum is a rare benign cystic tumor that originates from apocrine glands or anogenital mammary glands. Here, we describe 2 cases of hidradenoma papilliferum of the anus. Two female patients aged 39 and 35 presented with perianal masses with hemorrhoids. The patients underwent hemorrhoidectomy and excision of the lesion. Histopathology confirmed the masses as hidradenoma papilliferum. The postoperative course was uneventful for both patients, and there were no recurrences after 18 and 12 months of follow-up, respectively. Proctologists should consider hidradenoma papilliferum in their differential diagnosis of benign anal tumors. Surgical excision is necessary for diagnosis and treatment of hidradenoma papilliferum.

Citations

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  • Three Cases of Papillary Hidradenoma of the Anus
    Satoka Nasu
    Nihon Daicho Komonbyo Gakkai Zasshi.2024; 77(6): 360.     CrossRef
  • Hidradenoma papilliferum of the perineum; a rare tumour in a rare location
    Saliha Sağnıç, Sinan Serdar Ay, Hasan Aykut Tuncer, Selen Doğan, Tayup Şimşek
    Journal of Obstetrics and Gynaecology.2023;[Epub]     CrossRef

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