Annals of Coloproctology

Clinical Characteristics and Incidence of Perianal Diseases in Patients With Ulcerative Colitis: Yong Sung Choi, Do Sun Kim, Doo Han Lee, Jae Bum Lee, Eun Jung Lee, Seong Dae Lee, Kee Ho Song, Hyung Joong Jung; Ann Coloproctol. 2018;34(3):138-143. Published online June 30, 2018; DOI: https://doi.org/10.3393/ac.2017.06.08

6,526 View
172 Download
20 Web of Science
19 Citations

Purpose
While perianal disease (PAD) is a characteristic of patients with Crohn disease, it has been overlooked in patients with ulcerative colitis (UC). Thus, our study aimed to analyze the incidence and the clinical features of PAD in patients with UC.
Methods
We reviewed the data on 944 patients with an initial diagnosis of UC from October 2003 to October 2015. PAD was categorized as hemorrhoids, anal fissures, abscesses, and fistulae after anoscopic examination by experienced proctologists. Data on patients’ demographics, incidence and types of PAD, medications, surgical therapies, and clinical course were analyzed.
Results
The median follow-up period was 58 months (range, 12–142 months). Of the 944 UC patients, the cumulative incidence rates of PAD were 8.1% and 16.0% at 5 and 10 years, respectively. The incidence rates of bleeding hemorrhoids, anal fissures, abscesses, and fistulae at 10 years were 6.7%, 5.3%, 2.6%, and 3.4%, respectively. The cumulative incidence rates of perianal sepsis (abscess or fistula) were 2.2% and 4.5% at 5 and 10 years, respectively. In the multivariate analyses, male sex (risk ratio [RR], 4.6; 95% confidence interval [CI], 1.7–12.5) and extensive disease (RR, 4.2; 95% CI, 1.6–10.9) were significantly associated with the development of perianal sepsis.
Conclusion
Although the clinical course of PAD in patients with UC is not serious, in clinical practice, PAD is not rare in such patients. Therefore, careful examination and appropriate management for PAD is needed if the quality of life for patients with UC is to be improved.

Citations

Citations to this article as recorded by

Enhancing perianal disease management with integrated physical and psychological approaches
Uchenna E Okpete, Haewon Byeon
World Journal of Clinical Cases.2025;[Epub] CrossRef
The bacterial composition signatures of perianal abscess and origin of infecting microbes
Song Han, Wenya Su, Kefeng Fan, Zhen Xu, Hai Xu, Mingyu Wang, Ling Li, Wenlong Shen
PeerJ.2025; 13: e18855. CrossRef
Analysis of the permeable and retainable components of Cayratia japonica ointment through intact or broken skin after topical application by UPLC-Q-TOF-MS/MS combined with in vitro transdermal assay
Xuelong Zhao, Ruixue Dai, Jing Wang, Liangliang Cao, Peidong Chen, Weifeng Yao, Fangfang Cheng, Beihua Bao, Li Zhang
Journal of Pharmaceutical and Biomedical Analysis.2024; 238: 115853. CrossRef
Problem with Hookups: Perianal Fistula After Ileal Pouch-Anal Anastomosis
Arafa Djalal, Serre-Yu Wong, Jean-Frédéric Colombel, Ryan Ungaro, Maia Kayal
Digestive Diseases and Sciences.2024; 69(4): 1102. CrossRef
Diffusion-Weighted MRI in Perianal Abscess: Role and Comparison With Contrast-Enhanced MRI
Pooja Aggarwal, Rajesh Malik, Radha Sarawagi, Aman Kumar, Jitendra Sharma
Cureus.2024;[Epub] CrossRef
Inflammatory bowel disease and risk for hemorrhoids: a Mendelian randomization analysis
HanYu Wang, Lu Wang, XiaoYu Zeng, ShiPeng Zhang, Yong Huang, QinXiu Zhang
Scientific Reports.2024;[Epub] CrossRef
Associations of intestinal diseases with anal diseases: a Mendelian randomization study
XiaoYu Zeng, HanYu Wang, Ting Wu, ZiNing Zhou, JianPing Zhou, Hao Fu
Scientific Reports.2024;[Epub] CrossRef
Diagnosis and Differentiation of Inflammatory Bowel Disease
Kristen M. Westfall, Ronald Charles, Emily Steinhagen
Surgical Clinics of North America.2024;[Epub] CrossRef
Ulcerative colitis complicated with Fournier’s gangrene: A case report
Irina Bondoc, Marius Zamfir, Mara Mardare, Andrei Văcărașu, Alin Burlacu, Leila Ali, Ariana Hudita, Bianca Galateanu, Octav Ginghină, Georgios Georgiadis, Charalampos Mamoulakis
Public Health and Toxicology.2023; 3(1): 1. CrossRef
Causal Link between Inflammatory Bowel Disease and Fistula: Evidence from Mendelian Randomization Study
Zongbiao Tan, Shijie Zhu, Chuan Liu, Yang Meng, Jiao Li, Jixiang Zhang, Weiguo Dong
Journal of Clinical Medicine.2023; 12(7): 2482. CrossRef
Differences in Gut Microbiota between Healthy Individuals and Patients with Perianal Abscess before and after Surgery
Hezhai Yin, Bairu Luo, Qi Wang, Zhonghua Hong, Huilin Chen, Lidong Shen, Bin Shen, Bo Hu, Guangtao Xu
Mediators of Inflammation.2023; 2023: 1. CrossRef
Ulcerative colitis
Catherine Le Berre, Sailish Honap, Laurent Peyrin-Biroulet
The Lancet.2023; 402(10401): 571. CrossRef
Perianal Fistula After Ileoanal Pouch in Patients With Ulcerative Colitis: A Review of 475 Patients Operated on at a Major IBD Center
Tomas M. Heimann, Santosh Swaminathan, Gary I. Slater, Robert J. Kurtz
Diseases of the Colon & Rectum.2022; 65(1): 76. CrossRef
Prostaglandin E‐major urinary metabolite diagnoses mucosal healing in patients with ulcerative colitis in remission phase
Toshiyuki Sakurai, Yoshihiro Akita, Haruna Miyashita, Ryosuke Miyazaki, Yuki Maruyama, Tomoko Saito, Mariko Shimada, Takuji Yamasaki, Seiji Arhihiro, Tomohiro Kato, Tomokazu Matsuura, Masahiro Ikegami, Isao Okayasu, Masayuki Saruta
Journal of Gastroenterology and Hepatology.2022; 37(5): 847. CrossRef
Principles, Preparation, Indications, Precaution, and Damage Control of Endoscopic Therapy in Inflammatory Bowel Disease
Bo Shen
Gastrointestinal Endoscopy Clinics of North America.2022; 32(4): 597. CrossRef
Clinical characteristics and MRI-based phenotypes of perianal abscess formation in children with fistulizing Crohn's Disease
Azadeh Tabari, Jess L. Kaplan, Susanna Y. Huh, Christopher J. Moran, Michael S. Gee
Frontiers in Pediatrics.2022;[Epub] CrossRef
Inflammatory bowel diseases in Tamil Nadu: A survey of demographics, clinical profile, and practices
Rohan V Yewale, Kartik Natarajan, Jeyaraj Ubal Dhus, Sarojini Ashok Parameswaran, Kallipatti Ramaswamy Palaniswamy, Doraisamy Babu Vinish, Aravindh Somasundaram, Arulraj Ramakrishnan, Sibithooran Karmegam, Ramaswamy Saraswathy Arun, Ujjani Shankaraiah Man
JGH Open.2021; 5(11): 1306. CrossRef
Excisional haemorrhoidectomy: is it safe in patients with an ileal pouch–anal anastomosis?
A. L. Lightner, D. Kearney, D. Giugliano, T. Hull, S. Holubar, S. Shawki, S. R. Steele
Colorectal Disease.2020; 22(9): 1154. CrossRef
Hemorrhoidectomy and Excision of Skin Tags in IBD: Harbinger of Doom or Simply a Disease Running Its Course?
Nicholas P. McKenna, Amy L. Lightner, Elizabeth B. Habermann, Kellie L. Mathis
Diseases of the Colon & Rectum.2019; 62(12): 1505. CrossRef

Have Any Changes in Pain Been Noted After a Hemorrhoidectomy Since the Establishment of the Milligan-Morgan Hemorrhoidectomy?: Do Sun Kim; Ann Coloproctol. 2016;32(3):90-91. Published online June 30, 2016; DOI: https://doi.org/10.3393/ac.2016.32.3.90

3,129 View
54 Download

PDF

Persistent Bleeding Following a Stapled Hemorrhoidopexy: Seong Dae Lee, Sung Taek Jung, Jae-Bum Lee, Mi Jung Kim, Doo-Seok Lee, Eui-Gon Youk, Do-Sun Kim, Doo-Han Lee; Ann Coloproctol. 2016;32(3):120-122. Published online June 30, 2016; DOI: https://doi.org/10.3393/ac.2016.32.3.120

4,069 View
39 Download
1 Web of Science

Abstract PDF: A stapled hemorrhoidopexy (SH) is widely used for treatment of patients with grades III and IV hemorrhoids. The SH is easy to perform, is associated with less pain and allows early return to normal activities. However, complications, whether severe or not, have been reported. Here, we present the case of a female patient with persistent bleeding after a SH. The bleeding was caused by the formation of granulation tissue at the stapler line, diagnosed with sigmoidoscopy, and successfully treated via transanal excision (TAE) under spinal anesthesia. The biopsy showed inflammatory granulation tissue. After the TAE, her symptom was completely gone.

Advancement Flap for the Treatment of a Complex Anal Fistula: Do Sun Kim; Ann Coloproctol. 2014;30(4):161-162. Published online August 26, 2014; DOI: https://doi.org/10.3393/ac.2014.30.4.161

4,699 View
54 Download
2 Web of Science
3 Citations

PDF

Citations

Citations to this article as recorded by

Cutting seton for the treatment of cryptoglandular fistula-in-ano: a systematic review and meta-analysis
J. Khamar, A. Sachdeva, T. McKechnie, Y. Lee, L. Tessier, D. Hong, C. Eskicioglu
Techniques in Coloproctology.2024;[Epub] CrossRef
Evaluation of the Cutting Seton Technique in Treating High Anal Fistula
Asim M Almughamsi, Mohamed Khaled S Zaky, Abdullatif M Alshanqiti, Ibrahim S Alsaedi, Hamed I Hamed, Tariq E Alharbi, Ali A Elian
Cureus.2023;[Epub] CrossRef
Significance and Impact of the Intersphincteric Plane Sepsis in the Management of the Perianal Sepsis: Ultrasound Study
Ashraf Talaat Youssef
Journal of Gastrointestinal and Abdominal Radiology.2021; 04(02): 149. CrossRef

Histopathology and Physiological Alterations After Procedure for Prolapsed Hemorrhoids: Do Sun Kim; Ann Coloproctol. 2013;29(5):179-180. Published online October 31, 2013; DOI: https://doi.org/10.3393/ac.2013.29.5.179

3,184 View
32 Download

PDF

Intersphincteric Approach for Deep Postanal Sepsis: Do Sun Kim; Ann Coloproctol. 2013;29(2):39-40. Published online April 30, 2013; DOI: https://doi.org/10.3393/ac.2013.29.2.39

2,957 View
28 Download

PDF

Comparison of a Fistulectomy and a Fistulotomy with Marsupialization in the Management of a Simple Anal Fistula: A Randomized, Controlled Pilot Trial: Do Sun Kim; J Korean Soc Coloproctol. 2012;28(2):67-68. Published online April 30, 2012; DOI: https://doi.org/10.3393/jksc.2012.28.2.67

3,372 View
43 Download
3 Citations

PDF

Citations

Citations to this article as recorded by

Anti TNF treatment of complex perianal fistulas in children without luminal Crohn's disease: Is it an option?
Firas Rinawi, Mary-Louise C. Greer, Thomas Walters, Peter C. Church, Amanda Ricciuto, Jacob C. Langer, Anne M Griffiths
Journal of Pediatric Surgery.2022; 57(11): 569. CrossRef
The Effect of Topical and Oral Phenytoin on Increasing Wound Healing of Enterocutaneus Fistula in Wistar Rat
Victor Kurniawan, Hardian Hardian, Ignatius Riwanto
Open Access Macedonian Journal of Medical Sciences.2022; 10(A): 997. CrossRef
Operation for Posterior Intersphincteric Anal Fistula -Procedures of Fistulotomy-
Naoki Yago
Nippon Daicho Komonbyo Gakkai Zasshi.2013; 66(10): 1026. CrossRef

Signet Ring Cell Carcinoma Arising from a Solitary Juvenile Polyp in the Colon: Hae Jung Kim, Min Kwan Kang, Hee Suk Lee, Do Sun Kim, Du Han Lee; J Korean Soc Coloproctol. 2010;26(5):365-367. Published online October 31, 2010; DOI: https://doi.org/10.3393/jksc.2010.26.5.365

3,049 View
49 Download
6 Citations

Abstract PDF

Juvenile polyps are relatively common polyps that affect predominantly young patients and may occur in isolated, multiple, and/or familial forms. They have been considered to be benign lesions without neoplastic potential, but for patients with multiple juvenile polyposis, the cumulative malignant risk is greater than fifty percents. In patients with a solitary polyp, the risks are minimal, and only a few cases of malignant change from a solitary juvenile polyp have been reported. We describe the case of a twenty one year old female with one solitary juvenile polyp, which contained a signet ring cell carcinoma in the mucosal layer.

Citations

Citations to this article as recorded by

Solitary juvenile polyp of the rectum with intramucosal adenocarcinoma
Kazuki Nagai, Uichiro Fuchizaki, Yoshimichi Ueda
Clinical Journal of Gastroenterology.2023; 16(4): 532. CrossRef
Cancer risk and mortality in patients with solitary juvenile polyps—A nationwide cohort study with matched controls
Anne Marie Jelsig, Laus Wullum, Tine Plato Kuhlmann, Lilian Bomme Ousager, Johan Burisch, John Gásdal Karstensen
United European Gastroenterology Journal.2023; 11(8): 745. CrossRef
Characteristics and potential malignancy of colorectal juvenile polyps in adults: a single-center retrospective study in China
Jie Dong, Tian-Shi Ma, Yuan-Hong Xu, Peng Li, Wan-Yuan Chen, Jiang-Feng Tu, You-Wei Chen
BMC Gastroenterology.2022;[Epub] CrossRef
Can a Solitary Juvenile Polyp Be Regarded as a Nonmalignant Polyp?
Kumiko Fukami, Makoto Furihata, Shintaro Yano, Hiroki Okawa, Shinjiro Nishi, Yoichi Nakatsu, Yusuke Nomoto, Shingo Ogiwara, Tsuneo Kitamura, Shigeki Tomita, Taro Osada
ACG Case Reports Journal.2022; 9(12): e00936. CrossRef
Ultrasonography with the colonic segment-approach for colonic polyps in children
Yu Wang, Xiao Man Wang, Li Qun Jia
Pediatric Radiology.2019; 49(13): 1735. CrossRef
Signet ring cell carcinoma in a juvenile polyp
Carmen Villar Lucas, Mercedes Hernando Martín, Begoña Álvarez-Cuenllas
Revista Española de Enfermedades Digestivas.2019;[Epub] CrossRef

Search