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1 "Dong Min Kwak"
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Original Article
Effectiveness of Sodium Picosulfate/Magnesium Citrate (PICO) for Colonoscopy Preparation
Ki Hwan Song, Wu Seok Suh, Jin Sik Jeong, Dong Sik Kim, Sang Woo Kim, Dong Min Kwak, Jong Seong Hwang, Hyun Jin Kim, Man Woo Park, Min Chul Shim, Ja-Il Koo, Jae Hwang Kim, Dae Ho Shon
Ann Coloproctol. 2014;30(5):222-227.   Published online October 28, 2014
DOI: https://doi.org/10.3393/ac.2014.30.5.222
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  • 8 Web of Science
  • 6 Citations
AbstractAbstract PDF
Purpose

Bowel preparation with sodium phosphate was recently prohibited by the U.S. Food and Drug Administration. Polyethylene glycol (PEG) is safe and effective; however, it is difficult to drink. To identify an easy bowel preparation method for colonoscopy, we evaluated three different bowel preparation regimens regarding their efficacy and patient satisfaction.

Methods

In this randomized, comparative study, 892 patients who visited a secondary referral hospital for a colonoscopy between November 2012 and February 2013 were enrolled. Three regimens were evaluated: three packets of sodium picosulfate/magnesium citrate (PICO, group A), two packets of PICO with 1 L of PEG (PICO + PEG 1 L, group B), and two packets of PICO with 2 L of PEG (PICO + PEG 2 L, group C). A questionnaire survey regarding the patients' preference for the bowel preparation regimen and satisfaction was conducted before the colonoscopies. The quality of bowel cleansing was scored by the colonoscopists who used the Aronchick scoring scale and the Ottawa scale.

Results

The patients' satisfaction rate regarding the regimens were 72% in group A, 64% in group B, and 45.9% in group C. Nausea and abdominal bloating caused by the regimens were more frequent in group C than in group A or group B (P < 0.01). Group C showed the lowest preference rate compared to the other groups (P < 0.01). Group C showed better right colon cleansing efficacy than group A or group B.

Conclusion

Group A exhibited a better result than group B or group C in patient satisfaction and preference. In the cleansing quality, no difference was noted between groups A and C.

Citations

Citations to this article as recorded by  
  • White Diet with split‐dose Picosalax is preferred, better tolerated, and non‐inferior to day‐before clear fluids with polyethylene glycol plus sodium picosulfate‐magnesium citrate for morning colonoscopy: A randomized, non‐inferiority trial
    Jeremy P Dwyer, Jonathan Y C Tan, Eldho Paul, Catherine Bunn, Dileep Mangira, Robyn Secomb, Peter R Gibson, Gregor Brown
    JGH Open.2017; 1(1): 38.     CrossRef
  • Randomized clinical trial comparing fixed-time split dosing and split dosing of oral Picosulfate regimen for bowel preparation
    Jae Hyuck Jun, Koon Hee Han, Jong Kyu Park, Hyun Il Seo, Young Don Kim, Sang Jin Lee, Baek Gyu Jun, Min Sik Hwang, Yoon Kyoo Park, Myeong Jong Kim, Gab Jin Cheon
    World Journal of Gastroenterology.2017; 23(32): 5986.     CrossRef
  • Upper airway obstruction resulting from acute mucosal injury induced by direct ingestion of sodium picosulfate/magnesium citrate powder
    Gyeong Bo Kim, Sung Yeon Hwang, Tae Gun Shin, Tae Rim Lee, Won Chul Cha, Min Seob Sim, Ik Joon Jo, Keun Jeong Song, Joong Eui Rhee, Yeon Kwon Jeong
    Clinical and Experimental Emergency Medicine.2016; 3(2): 109.     CrossRef
  • Combination could be another tool for bowel preparation?
    Jae Seung Soh, Kyung-Jo Kim
    World Journal of Gastroenterology.2016; 22(10): 2915.     CrossRef
  • Phase II Randomized Controlled Trial of Combined Oral laxatives Medication for BOwel PREParation (COMBO-PREP study)
    Min Jung Kim, Chang Won Hong, Byung Chang Kim, Sung Chan Park, Kyung Su Han, Jungnam Joo, Jae Hwan Oh, Dae Kyung Sohn
    Medicine.2016; 95(7): e2824.     CrossRef
  • Frustration Still Exists
    Hyun Shig Kim
    Annals of Coloproctology.2014; 30(5): 207.     CrossRef
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