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Guidelines
Colorectal cancer
The Korean Rectal Cancer Multidisciplinary Committee Clinical Practice Guidelines for Rectal Cancer version 2.0
Hyo Seon Ryu, Hyun Jung Kim, Dong Hyun Kang, Yoo-Kang Kwak, Han Deok Kwak, Yoon-Hye Kwon, Dalyong Kim, Baek-Hui Kim, Jae Hyun Kim, Ji Hun Kim, Jin Won Kim, Tae Hyung Kim, Hae Young Kim, Soo Min Nam, Gyoung Tae Noh, Jun Woo Bong, Nak Song Sung, Seon Hui Shin, Kil-Yong Lee, Sung Chul Lee, Sea-Won Lee, Jung Won Lee, Jong Min Lee, Myung Hoon Ihn, Joo Han Lim, Woong Bae Ji, Dae Hee Pyo, Young Ki Hong, Jung-Myun Kwak, on behalf of the Korean Rectal Cancer Multidisciplinary (KRCM) Committee
Ann Coloproctol. 2026;42(1):4-33.   Published online February 24, 2026
DOI: https://doi.org/10.3393/ac.2025.01396.0199
  • 2,298 View
  • 183 Download
AbstractAbstract PDFSupplementary Material
Rectal cancer, which accounts for approximately 40% of colorectal cancers, remains a major clinical concern. Recent advances in diagnostic imaging, surgical techniques, radiotherapy, and systemic treatment have steadily improved rectal cancer outcomes. Considering this, the Korean Rectal Cancer Multidisciplinary (KRCM) Committee has aimed to provide clinicians and policymakers with up-to-date, evidence-based clinical practice guidelines to support optimal decision-making, reflecting current evidence, the Korean healthcare context, and patient values and preferences. The Clinical Practice Guidelines for Rectal Cancer version 2.0 were developed through multidisciplinary collaboration with related academic societies, building upon and updating the KRCM Clinical Practice Guidelines version 1.0 (titled “Multidisciplinary guidelines for the management of rectal cancer”). These consensus guidelines of the KRCM were established based on a comprehensive literature review, evidence synthesis, with recommendation development guided by the GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology, and consideration of applicability in real-world clinical practice under the national health insurance system. Each recommendation has been presented with its strength and level of evidence.
Colorectal cancer
Colon cancer: the 2023 Korean clinical practice guidelines for diagnosis and treatment
Hyo Seon Ryu, Hyun Jung Kim, Woong Bae Ji, Byung Chang Kim, Ji Hun Kim, Sung Kyung Moon, Sung Il Kang, Han Deok Kwak, Eun Sun Kim, Chang Hyun Kim, Tae Hyung Kim, Gyoung Tae Noh, Byung-Soo Park, Hyeung-Min Park, Jeong Mo Bae, Jung Hoon Bae, Ni Eun Seo, Chang Hoon Song, Mi Sun Ahn, Jae Seon Eo, Young Chul Yoon, Joon-Kee Yoon, Kyung Ha Lee, Kyung Hee Lee, Kil-Yong Lee, Myung Su Lee, Sung Hak Lee, Jong Min Lee, Ji Eun Lee, Han Hee Lee, Myong Hoon Ihn, Je-Ho Jang, Sun Kyung Jeon, Kum Ju Chae, Jin-Ho Choi, Dae Hee Pyo, Gi Won Ha, Kyung Su Han, Young Ki Hong, Chang Won Hong, Jung-Myun Kwak, Korean Colon Cancer Multidisciplinary Committee
Ann Coloproctol. 2024;40(2):89-113.   Published online April 30, 2024
DOI: https://doi.org/10.3393/ac.2024.00059.0008
  • 20,844 View
  • 564 Download
  • 13 Web of Science
  • 15 Citations
AbstractAbstract PDFSupplementary Material
Colorectal cancer is the third most common cancer in Korea and the third leading cause of death from cancer. Treatment outcomes for colon cancer are steadily improving due to national health screening programs with advances in diagnostic methods, surgical techniques, and therapeutic agents.. The Korea Colon Cancer Multidisciplinary (KCCM) Committee intends to provide professionals who treat colon cancer with the most up-to-date, evidence-based practice guidelines to improve outcomes and help them make decisions that reflect their patients’ values and preferences. These guidelines have been established by consensus reached by the KCCM Guideline Committee based on a systematic literature review and evidence synthesis and by considering the national health insurance system in real clinical practice settings. Each recommendation is presented with a recommendation strength and level of evidence based on the consensus of the committee.

Citations

Citations to this article as recorded by  
  • Are the long-term oncologic outcomes different between appendiceal cancer and right-sided colon cancer? An exact matching analysis of a 10-year institutional cohort
    Gunwoo Lee, Eun Jung Park, Soo Young Oh, Young Il Kim, Min Hyun Kim, Jong Lyul Lee, Chan Wook Kim, Yong Sik Yoon, In Ja Park, Seok-Byung Lim, Chang Sik Yu
    Annals of Surgical Treatment and Research.2026; 110(4): 246.     CrossRef
  • Impact of Adjuvant Chemotherapy on the Prognosis in Elderly Patients with Stage II and III Colorectal Cancer: A Retrospective Multicenter Study
    Eui Myung Kim, Il Son, Byung Chun Kim, Jun Park, Jin Won Lee, Jong Wan Kim
    Cancer Management and Research.2026; Volume 18: 1.     CrossRef
  • Lynch Syndrome in the Asian American Population: A Review of the Literature
    Wai Park, Ashley Mochizuki, Lauren Gima, Joanne M. Jeter
    Cancers.2026; 18(9): 1456.     CrossRef
  • Optimal extent of lymph node dissection in clinical early-stage right colon cancer: a retrospective analysis
    Hyeung-min Park, Jaram Lee, Soo Young Lee, Suk Hee Heo, Yong Yeon Jeong, Hyeong Rok Kim, Chang Hyun Kim
    Annals of Surgical Treatment and Research.2025; 108(1): 49.     CrossRef
  • Effects of Microsatellite Instability on the Clinical and Pathological Characteristics of Colon Cancer and the Diagnostic Accuracy of Preoperative Abdominal CT Scans
    Rıdvan Yavuz, Orhan Aras, Hüseyin Çiyiltepe, Onur İlkay Dinçer, Ahmet Şükrü Alparslan, Tebessüm Çakır
    Diagnostics.2025; 15(2): 190.     CrossRef
  • Epigenetic Regulation of Nuclear Factor Erythroid-2-Related Factor 2 in Colorectal Cancer Cells Resistant to Ionizing Radiation
    Kyoung Ah Kang, Jinny Park, Mei Jing Piao, Pincha Devage Sameera Madushan Fernando, Herath Mudiyanselage Udari Lakmini Herath, Herath Mudiyanselage Maheshika Madhuwanthi Senavirathna, Jung-Hwan Kim, Suk Ju Cho, Jin Won Hyun
    Biomolecules & Therapeutics.2025; 33(1): 182.     CrossRef
  • Meeting report on the 8th Asian Science Editors’ Conference and Workshop 2024
    Eun Jung Park
    Science Editing.2025; 12(1): 66.     CrossRef
  • The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases
    İhsaniye Süer Doğan, Esin Çakmakçı Midia, Yıldıran Songür, Baki Hekimoğlu
    Turkish Journal of Clinics and Laboratory.2025; 16(1): 27.     CrossRef
  • National Guidelines for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Peritoneal Malignancies: A Worldwide Systematic Review and Recommendations of Strength Analysis
    Marco Tonello, Carola Cenzi, Elisa Pizzolato, Manuela Martini, Pierluigi Pilati, Antonio Sommariva
    Annals of Surgical Oncology.2025; 32(8): 5795.     CrossRef
  • Advancements in Image‐Based Analyses for Morphology and Staging of Colon Cancer: A Comprehensive Review
    Samuel Arthur Ameyaw, Derrick Adu Afari, John Boateng, Marcello Maida
    BioMed Research International.2025;[Epub]     CrossRef
  • Curcumin in colorectal cancer: preventive strategies and therapeutic mechanisms
    Amit Sharma, Bhavin Parekh, Vinay Patil, Usamah Sayed, Renuka Jyothi, Priya Priyadarshini Nayak, Ashish Singh Chauhan, Siya Singla
    Cancer Chemotherapy and Pharmacology.2025;[Epub]     CrossRef
  • 2023 Korean Multidisciplinary Guidelines for Colon Cancer Management: Summary of Radiological Points
    Nieun Seo, Hyo Seon Ryu, Myungsu Lee, Sun Kyung Jeon, Kum Ju Chae, Joon-Kee Yoon, Kyung Su Han, Ji Eun Lee, Jae Seon Eo, Young Chul Yoon, Sung Kyung Moon, Hyun Jung Kim, Jung-Myun Kwak
    Korean Journal of Radiology.2024; 25(9): 769.     CrossRef
  • Effect of Fluorescence Lymph Node Mapping on Improving Diagnostic Values of CT D3 Lymph Node Staging for Right-Sided Colon Cancer
    Gyung Mo Son, Tae Un Kim, Mi Sook Yun, ChangYeop Kim, In Young Lee, Su Bum Park, Dong-Hoon Shin, Gi Won Ha
    Cancers.2024; 16(20): 3496.     CrossRef
  • Nuclear medicine based multimodal molecular imaging facilitates precision medicine for gastrointestinal tumors
    Jing Zhao, Fei Wang, Rong-Fu Wang
    World Chinese Journal of Digestology.2024; 32(10): 727.     CrossRef
  • Impact of Early Oral Feeding on Postoperative Outcomes after Elective Colorectal Surgery: A Systematic Review and Meta-Analysis
    Soo Young Lee, Eon Chul Han
    Digestive Surgery.2024; : 1.     CrossRef
Original Article
A comparative study of rubber band ligation versus BANANA-Clip in grade 1 to 3 internal hemorrhoids
Dong Wan Kang, Byoung Soo Kim, Ji Hun Kim, Kyong Rae Kim, Gyong Suk Kang
Ann Coloproctol. 2023;39(1):41-49.   Published online December 9, 2021
DOI: https://doi.org/10.3393/ac.2021.00717.0102
  • 14,278 View
  • 340 Download
  • 3 Web of Science
  • 7 Citations
Graphical AbstractGraphical Abstract AbstractAbstract PDF
Purpose
Rubber band ligation (RBL) for grade 1 to 3 internal hemorrhoids is a well-established modality of choice. But RBL is also a kind of surgical treatment; it is not free from complications (e.g., delayed bleeding [DB], rectal stenosis). This study aimed to investigate the results of the comparative treatment of RBL and BANANA-Clip (BC; Endovision).
Methods
Study participants were 632 consecutive patients with grade 1 to 3 internal hemorrhoids attended to Department of Colorectal Surgery at Wellness Hospital between January 2010 and May 2019. We retrospectively reviewed the incidence rate of complications, including DB between RBL and BC.
Results
There were 304 male and 328 female patients, whose ages ranged from 15 to 84 years, with a mean age of 45.7 years. The common symptom and cause of treatment was prolapse (70.1%). The number of ligated sites was 1.49±0.57 in the RBL group and 1.99±0.77 in the BC group. RBL showed a significantly higher incidence of DB (3.5%) compared to BC (0%) (P=0.001). The 1-year success rate was 95.9% in the RBL group and 99.7% in the BC group (P=0.005).
Conclusion
In our study, BC was more reliable in treating grade 1 to 3 internal hemorrhoids with higher success rates and less post-ligation complications, especially DB, compared to RBL.

Citations

Citations to this article as recorded by  
  • Latest Research Trends on the Management of Hemorrhoids
    Sung Il Kang
    Journal of the Anus, Rectum and Colon.2025; 9(2): 179.     CrossRef
  • Management of Internal Hemorrhoidal Disease by Elastic Ligation in Ouagadougou, Burkina Faso
    Aboubacar Coulibaly, Zitgnimian Souleymane Sanne, Brunel Fernandez Keubou Zebaze, Sougrinoma Issouf Abel Sawadogo, Yamba Elie Sawadogo, Léonce Zoungrana, Kounpièlimè Sosthène Somda, Arsène Roger Sombie
    Open Journal of Gastroenterology.2025; 15(07): 367.     CrossRef
  • Lower pain, less itching, and faster healing after ultrasound scalpel-assisted hemorrhoidectomy using an intimate cleaner containing chlorhexidine, acid hyaluronic acid, and natural anti-inflammatories: a multicenter observational case-control study
    Antonio Brillantino, Luigi Marano, Maurizio Grillo, Alessio Palumbo, Fabrizio Foroni, Luciano Vicenzo, Alessio Antropoli, Michele Lanza, Maria Laura Sandoval Sotelo, Nicola Sangiuliano, Mauro Maglio, Rosanna Filosa, Lucia Abbatiello, Maria Preziosa Romano
    Annals of Coloproctology.2024; 40(6): 602.     CrossRef
  • The BANANA-Clip: an innovative solution for hemorrhoidal pile ligation?
    Kyung Uk Jung
    Annals of Coloproctology.2023; 39(1): 1.     CrossRef
  • Banana Clip: Advancing Hemorrhoid Ligation Beyond Rubber Bands
    Navneet Arora, Ranjeet Kumar
    Journal of Coloproctology.2023; 43(04): e324.     CrossRef
  • Effectiveness of Mayinglong Musk Hemorrhoid Ointment on Wound Healing and Complications after Internal Hemorrhoid Ligation and External Hemorrhoidectomy
    Sen Lin, Meichun Zang, Zhaoqi Dong
    Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1.     CrossRef
  • Modified rubber band ligation for treatment of grade II/III hemorrhoids: clinical efficacy and safety evaluation—a retrospective study
    Jiazi Yu, Jie Zhong, Tao Peng, Liangbin Jin, Leibin Shen, Mian Yang
    BMC Surgery.2022;[Epub]     CrossRef
Case Report
Benign GI diease,Rare disease & stoma,Complication
Acute Ileal Perforation Caused by Radiation Enteritis After Restoration
Jong Beom Kim, Jong Lyul Lee, Seong Ho Park, Jihun Kim, Jin Cheon Kim
Ann Coloproctol. 2021;37(Suppl 1):S51-S54.   Published online September 18, 2020
DOI: https://doi.org/10.3393/ac.2020.07.30
  • 5,901 View
  • 65 Download
  • 3 Web of Science
  • 4 Citations
AbstractAbstract PDF
Few radiation-induced bowel perforations have been reported to date. Furthermore, perforation after ileal restoration in asymptomatic patients is rare. We report the case of a 61-year-old man who was administered preoperative chemoradiotherapy for advanced rectal cancer. The patient underwent ultra-low anterior resection with ileal diversion, followed by ileal restoration. Perforation was detected 9 days after restoration, and he underwent a right hemicolectomy. The histologic evaluation indicated ileal perforation caused by acute radiation enteritis.

Citations

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  • MR Imaging of Anal Cancer
    Josip Nincevic, Gaiane M. Rauch, Jennifer S. Golia Pernicka
    Radiologic Clinics of North America.2025; 63(3): 435.     CrossRef
  • Pathological classification of chronic radiation-induced intestinal injury and its clinical implications
    Yi-Ting Wang, Ya-Xi Zhu, Rui-Yan Huang, Yan Huang, Xiang-Bo Wan, Xiao-Yan Huang, Qing-Hua Zhong, Qi-Yuan Qin, Yun-Long Wang, Teng-Hui Ma, Xin-Juan Fan
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    Wenwen Fu, Lina Zhang, Tenghui Ma
    Aging Research.2023; 1(2): 9340016.     CrossRef
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