Annals of Coloproctology

Display

Sort by :

Case Report

Giant Ascending Colonic Diverticulum Presenting With Intussusception: Ho Jin Kim, Jin Ha Kim, Ok In Moon, Kyung Jong Kim; Ann Coloproctol. 2013;29(5):209-212. Published online October 31, 2013; DOI: https://doi.org/10.3393/ac.2013.29.5.209

5,106 View
54 Download
10 Citations

Diverticular disease of the colon is a common disease, and its incidence is increasing gradually. A giant colonic diverticulum (GCD) is a rare entity and is defined as a diverticulum greater than 4 cm in size. It mainly arises from the sigmoid colon, and possible etiology is a ball-valve mechanism permitting progressive enlargement. A plain abdominal X-ray can be helpful to make a diagnosis initially, and a barium enema and abdominal computed tomography may confirm the diagnosis. Surgical intervention is a definite treatment for a GCD. We report a case of an ascending GCD presenting with intussusception in a young adult.

Citations

Citations to this article as recorded by

Intussusception secondary to retroflexion of a proximal jejunal diverticulum, leading to Type 3 vagal indigestion with severe hypochloraemia in an adult Simmental bull (Bos taurus)
Liam A. Wilson, Rob F. Kelly, Adrian W. Philbey
Veterinary Record Case Reports.2024;[Epub] CrossRef
A case report of impacted fecalith within mucosal pouch: an unusual cause of colocolic intussusception
Douglas Greer, Adrian Fernandez
Annals of Coloproctology.2024; 40(Suppl 1): S15. CrossRef
Popping the Balloon: A Giant Colonic Diverticulum Complicated by Bladder Neck Compression
M. C. Ripoli, A. Lauro, S. Vaccari, G. Mastrocola, A. Lanci-Lanci, V. D’Andrea, I. R. Marino, M. Cervellera, V. Tonini
Digestive Diseases and Sciences.2021; 66(1): 41. CrossRef
Laparoscopic resection of a giant colonic diverticulum – the ‘lifting balloon’ sign – a video vignette
C. Rodríguez‐Otero Luppi, M. Rodríguez Blanco, J. Bollo Rodríguez, A. Méndez, J. Merlo Más
Colorectal Disease.2019; 21(9): 1096. CrossRef
Intussusception caused by an inverted colonic diverticulum: a case report
Bei Zhang, Jiping Wang, Xiaoguang Li, Zhuo Wang, Yangjiao Zhang, Hao Yang
Journal of Medical Case Reports.2018;[Epub] CrossRef
Adult intussusception secondary to diverticular disease
Habib Syed, Labib Syed, Umesh Parampalli, Mokhtar Uheba
BMJ Case Reports.2018; 2018: bcr-2018-226678. CrossRef
Laparoskopische Resektion eines Riesenkolondivertikels
P. J. Roch, T. Friedrich, R. Bönninghoff, D. Dinter, A. Rickert
Der Chirurg.2017; 88(8): 682. CrossRef
Giant colonic diverticulum: radiographic and MDCT characteristics
Abdel-Rauf Zeina, Ahmad Mahamid, Alicia Nachtigal, Itamar Ashkenazi, Mika Shapira-Rootman
Insights into Imaging.2015; 6(6): 659. CrossRef
Giant colonic diverticulum: Clinical presentation, diagnosis and treatment: Systematic review of 166 cases
Giuseppe Nigri
World Journal of Gastroenterology.2015; 21(1): 360. CrossRef
Giant Colonic Diverticulum: a Rare Diagnostic and Therapeutic Challenge of Diverticular Disease
Ryan Macht, Holly K. Sheldon, P. Marco Fisichella
Journal of Gastrointestinal Surgery.2015; 19(8): 1559. CrossRef

Original Article

Prognostic Implication of 15-Hydroxyprostaglandin Dehydrogenase Down-Regulation in Patients with Colorectal Cancer: Pil Sung Kang, Jin Ha Kim, Ok In Moon, Sung Chul Lim, Kyung Jong Kim; J Korean Soc Coloproctol. 2012;28(5):253-258. Published online October 31, 2012; DOI: https://doi.org/10.3393/jksc.2012.28.5.253

4,643 View
50 Download
2 Citations

Abstract PDF

Purpose

Prostaglandin (PG) E2 is known to be closely related to cancer progression and is inactivated by 15-hydroxyprostaglandin dehydrogenase (PGDH). 15-PGDH is shown to have tumor suppressor activity and to be down-regulated in various cancers, including colorectal cancer (CRC). Therefore, we evaluated the expression of 15-PGDH and its prognostic effect in patients with CRC.

Methods

15-PGDH expression was examined by using immunohistochemistry in 77 patients with CRC. Its prognostic significance was statistically evaluated.

Results

Negative 15-PGDH expression was noted in 55.8% of the 77 cases of CRC. 15-PGDH expression showed no correlation with any of the various clinicopathologic parameters. The status of lymph node metastasis, tumor-node-metastasis stages, and pre-operative carcinoembryonic antigen levels showed significant prognostic effect. However, univariate analysis revealed down-regulation of 15-PGDH not to be a predictor of poor survival. The 5-year overall survival rate was 71.7% in the group with positive expression of 15-PGDH and 67.1% in the group with negative expression of 15-PGDH, but this difference was not statistically significant (P = 0.751).

Conclusion

15-PGDH was down-regulated in 55.8% of the colorectal cancer patients. However, down-regulation of 15-PGDH showed no prognostic value in patients with CRC. Further larger scale or prospective studies are needed to clarify the prognostic effect of 15-PGDH down-regulation in patients with colorectal cancer.

Citations

Citations to this article as recorded by

The tumor suppressor role and epigenetic regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in cancer and tumor microenvironment (TME)
SubbaRao V. Tulimilli, Medha Karnik, Anjali Devi S. Bettadapura, Olga A. Sukocheva, Edmund Tse, Gowthamarajan Kuppusamy, Suma M. Natraj, SubbaRao V. Madhunapantula
Pharmacology & Therapeutics.2025; 268: 108826. CrossRef
Molecular Targets in Precision Chemoprevention of Colorectal Cancer: An Update from Pre-Clinical to Clinical Trials
Nagendra S. Yarla, Venkateshwar Madka, Gopal Pathuri, Chinthalapally V. Rao
International Journal of Molecular Sciences.2020; 21(24): 9609. CrossRef

First
Prev
Page of 1
Next
Last

Search