Skip Navigation
Skip to contents

Ann Coloproctol : Annals of Coloproctology

OPEN ACCESS
SEARCH
Search

Search

Page Path
HOME > Search
9 "Kyung Ha Lee"
Filter
Filter
Article category
Keywords
Publication year
Authors
Guideline
Colorectal cancer
Colon cancer: the 2023 Korean clinical practice guidelines for diagnosis and treatment
Hyo Seon Ryu, Hyun Jung Kim, Woong Bae Ji, Byung Chang Kim, Ji Hun Kim, Sung Kyung Moon, Sung Il Kang, Han Deok Kwak, Eun Sun Kim, Chang Hyun Kim, Tae Hyung Kim, Gyoung Tae Noh, Byung-Soo Park, Hyeung-Min Park, Jeong Mo Bae, Jung Hoon Bae, Ni Eun Seo, Chang Hoon Song, Mi Sun Ahn, Jae Seon Eo, Young Chul Yoon, Joon-Kee Yoon, Kyung Ha Lee, Kyung Hee Lee, Kil-Yong Lee, Myung Su Lee, Sung Hak Lee, Jong Min Lee, Ji Eun Lee, Han Hee Lee, Myong Hoon Ihn, Je-Ho Jang, Sun Kyung Jeon, Kum Ju Chae, Jin-Ho Choi, Dae Hee Pyo, Gi Won Ha, Kyung Su Han, Young Ki Hong, Chang Won Hong, Jung-Myun Kwak, Korean Colon Cancer Multidisciplinary Committee
Ann Coloproctol. 2024;40(2):89-113.   Published online April 30, 2024
DOI: https://doi.org/10.3393/ac.2024.00059.0008
  • 2,911 View
  • 241 Download
  • 2 Web of Science
  • 3 Citations
AbstractAbstract PDFSupplementary Material
Colorectal cancer is the third most common cancer in Korea and the third leading cause of death from cancer. Treatment outcomes for colon cancer are steadily improving due to national health screening programs with advances in diagnostic methods, surgical techniques, and therapeutic agents.. The Korea Colon Cancer Multidisciplinary (KCCM) Committee intends to provide professionals who treat colon cancer with the most up-to-date, evidence-based practice guidelines to improve outcomes and help them make decisions that reflect their patients’ values and preferences. These guidelines have been established by consensus reached by the KCCM Guideline Committee based on a systematic literature review and evidence synthesis and by considering the national health insurance system in real clinical practice settings. Each recommendation is presented with a recommendation strength and level of evidence based on the consensus of the committee.

Citations

Citations to this article as recorded by  
  • 2023 Korean Multidisciplinary Guidelines for Colon Cancer Management: Summary of Radiological Points
    Nieun Seo, Hyo Seon Ryu, Myungsu Lee, Sun Kyung Jeon, Kum Ju Chae, Joon-Kee Yoon, Kyung Su Han, Ji Eun Lee, Jae Seon Eo, Young Chul Yoon, Sung Kyung Moon, Hyun Jung Kim, Jung-Myun Kwak
    Korean Journal of Radiology.2024; 25(9): 769.     CrossRef
  • Effect of Fluorescence Lymph Node Mapping on Improving Diagnostic Values of CT D3 Lymph Node Staging for Right-Sided Colon Cancer
    Gyung Mo Son, Tae Un Kim, Mi Sook Yun, ChangYeop Kim, In Young Lee, Su Bum Park, Dong-Hoon Shin, Gi Won Ha
    Cancers.2024; 16(20): 3496.     CrossRef
  • Nuclear medicine based multimodal molecular imaging facilitates precision medicine for gastrointestinal tumors
    Jing Zhao, Fei Wang, Rong-Fu Wang
    World Chinese Journal of Digestology.2024; 32(10): 727.     CrossRef
Original Articles
Colorectal cancer
Computed tomography–assessed presarcopenia and clinical outcomes after laparoscopic surgery for rectal cancer
Ji Hyeong Song, Rak Kyun Oh, Jeong Eun Lee, Kyung Ha Lee, Ji Yeon Kim, Jin Soo Kim
Ann Coloproctol. 2023;39(6):513-520.   Published online December 12, 2023
DOI: https://doi.org/10.3393/ac.2023.00031.0004
  • 1,567 View
  • 99 Download
AbstractAbstract PDF
Purpose
Previous studies have reported that presarcopenia negatively affects rectal cancer treatment. However, most studies have analyzed patients including majority of open surgery, and the association between presarcopenia and clinical outcomes after laparoscopic rectal cancer surgery remains unclear. This study aimed to evaluate the impact of presarcopenia on the clinical and oncological outcomes after laparoscopic rectal cancer surgery.
Methods
Three hundred and one patients undergoing laparoscopic rectal cancer surgery between December 2009 and May 2016 were enrolled. Body composition was assessed using computed tomography by measuring the muscle and fat areas at the third lumbar (L3) vertebra. The L3 skeletal muscle area was used to calculate the skeletal muscle index and evaluate presarcopenia.
Results
Presarcopenia was more common in older ( ≥ 70 years, P = 0.008) or female patients (P = 0.045). Patients with presarcopenia had decreased skeletal muscle area (P < 0.001), lower hemoglobin level (P = 0.034), longer time to first flatus (P < 0.001), and more frequent surgical site infection (P = 0.001). However, survival rates were not significantly different between those with and without presarcopenia.
Conclusion
Computed tomography-assessed presarcopenia was associated with delayed functional recovery and increased surgical site infection, although it was not revealed as a prognostic factor for oncological outcomes.
Malignant disease,Prognosis and adjuvant therapy,Colorectal cancer,Biomarker & risk factor
Prognostic Factor and Survival Benefit of Adjuvant Chemotherapy in Stage IIA Colon Cancer
Mok-Won Lee, Jin-Su Kim, Ji-Yeon Kim, Kyung-ha Lee
Ann Coloproctol. 2021;37(1):35-43.   Published online September 18, 2020
DOI: https://doi.org/10.3393/ac.2020.09.03
  • 3,417 View
  • 130 Download
  • 8 Web of Science
  • 8 Citations
AbstractAbstract PDF
Purpose
There is no clear evidence of the benefit of adjuvant chemotherapy (AC) in stage IIA colon cancer. Therefore, we aimed to evaluate the prognostic factors and survival benefit of AC in this disease.
Methods
A retrospective data collection for patients who underwent radical surgery for colon cancer between January 2008 and December 2015 was undertaken. The cohort was divided into the no-AC and AC groups.
Results
We included 227 patients with stage IIA colon cancer in our study cohort, including 67 and 160 patients in the no-AC and AC groups, respectively. The number of retrieved lymph nodes and the presence of tumor complications as obstruction or perforation were independent risk factors for survival. In the no-AC group, there was a significant difference in survival according to the number of retrieved lymph nodes. In the AC group, there were significant differences in survival according to sidedness and preoperative carcinoembryonic antigen (CEA). There was no significant difference in survival between the no-AC and the AC groups.
Conclusion
The number of retrieved lymph nodes and the presence of tumor complications were prognostic factors for stage IIA colon cancer but lymphovascular and perineural invasion were not. Sidedness and preoperative CEA could be used as factors to predict the benefit of adjuvant chemotherapy. Currently, it is believed that there is no benefit of AC for stage IIA colon cancer. Further studies are needed to determine the survival benefit of adjuvant chemotherapy in stage IIA colon cancer.

Citations

Citations to this article as recorded by  
  • Can clinicopathologic high-risk features in T3N0 colon cancer be reliable prognostic factors?
    Hyun Gu Lee, Young IL Kim, In Ja Park, Seok-Byung Lim, Chang Sik Yu
    Annals of Surgical Treatment and Research.2023; 104(2): 109.     CrossRef
  • Clinical Effectiveness of Fluorescence Lymph Node Mapping Using ICG for Laparoscopic Right Hemicolectomy: A Prospective Case–Control Study
    Gyung Mo Son, Mi Sook Yun, In Young Lee, Sun Bin Im, Kyung Hee Kim, Su Bum Park, Tae Un Kim, Dong-Hoon Shin, Armaan M. Nazir, Gi Won Ha
    Cancers.2023; 15(20): 4927.     CrossRef
  • Impact of Postoperative Naples Prognostic Score to Predict Survival in Patients with Stage II–III Colorectal Cancer
    Su Hyeong Park, Hye Seung Woo, In Kyung Hong, Eun Jung Park
    Cancers.2023; 15(20): 5098.     CrossRef
  • The Prognostic Reliability of Lymphovascular Invasion for Patients with T3N0 Colorectal Cancer in Adjuvant Chemotherapy Decision Making
    Hayoung Lee, Seung-Yeon Yoo, In Ja Park, Seung-Mo Hong, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
    Cancers.2022; 14(12): 2833.     CrossRef
  • Molecular Analyses in Peritoneal Metastasis from Colorectal Cancer: A Review-An English Version
    Chang Hyun Kim
    Journal of the Anus, Rectum and Colon.2022; 6(4): 197.     CrossRef
  • Adjuvant chemotherapy benefits on patients with elevated carcinoembryonic antigen in stage IIA colon cancer: a SEER-based analysis
    Huabin Zhou, Songsheng Wang, Zhai Cai, Enming Qiu, Qianyun Chen, Xi Rao, Shuai Han, Zhou Li
    International Journal of Colorectal Disease.2022; 37(12): 2481.     CrossRef
  • Molecular analyses of peritoneal metastasis from colorectal cancer
    Chang Hyun Kim
    Journal of the Korean Medical Association.2022; 65(9): 586.     CrossRef
  • Direction of diagnosis and treatment improvement in colorectal cancer
    In Ja Park
    Journal of the Korean Medical Association.2022; 65(9): 540.     CrossRef
Case Report
Benign GI diease,Rare disease & stoma,Complication
Intestinal Perforation as a Paradoxical Reaction to Antitubercular Therapy: A Case Report
Sung Hoon Kang, Hee Seok Moon, Jae Ho Park, Ju Seok Kim, Sun Hyung Kang, Eaum Seok Lee, Seok Hyun Kim, Byung Seok Lee, Jae Kyu Sung, Hyun Yong Jeong, Kyung Ha Lee
Ann Coloproctol. 2021;37(Suppl 1):S18-S23.   Published online May 15, 2020
DOI: https://doi.org/10.3393/ac.2020.03.16.1
  • 3,653 View
  • 113 Download
  • 2 Web of Science
  • 3 Citations
AbstractAbstract PDF
Paradoxical reactions to tuberculosis (TB) treatment are characterized by an initial improvement of the clinical symptoms followed by clinical or radiological deterioration of existing tuberculous lesions, or by development of new lesions. Intestinal perforation in gastrointestinal TB can occur as a paradoxical reaction to antitubercular therapy. A 55-year-old man visited the outpatient department with lower abdominal pain and weight loss. He was diagnosed with intestinal TB and started antitubercular therapy. After 3 months of antitubercular therapy, a colonoscopy revealed improvement of the disease. Three days after the colonoscopy, the patient visited the emergency room complaining of abdominal pain. Abdominal computed tomography revealed extraluminal air-filled spaces in the pelvic cavity. We diagnosed a small bowel perforation and performed an emergency laparotomy and a right hemicolectomy with small bowel resection. This report describes the case of intestinal perforation presenting as a paradoxical reaction to antitubercular and provides a brief literature review.

Citations

Citations to this article as recorded by  
  • Réaction paradoxale tuberculeuse
    L.-D. Azoulay, A.-L. Houist, E. Feredj, W. Vindrios, S. Gallien
    La Revue de Médecine Interne.2024; 45(5): 279.     CrossRef
  • Paradoxical Reaction to Antitubercular Treatment Causing Colonic Obstruction
    Akira Hokama, Yuiko Oishi, Erika Koga, Sayuri Takehara, Jiro Fujita
    Chonnam Medical Journal.2022; 58(1): 52.     CrossRef
  • Multiple drugs

    Reactions Weekly.2021; 1881(1): 189.     CrossRef
Original Article
Combination Assessment of Clinical Complete Response of Patients With Rectal Cancer Following Chemoradiotherapy With Endoscopy and Magnetic Resonance Imaging
Hye Mi Ko, Yo Han Choi, Jeong Eun Lee, Kyung Ha Lee, Ji Yeon Kim, Jin Soo Kim
Ann Coloproctol. 2019;35(4):202-208.   Published online August 31, 2019
DOI: https://doi.org/10.3393/ac.2018.10.15
  • 4,327 View
  • 162 Download
  • 14 Web of Science
  • 15 Citations
AbstractAbstract PDF
Purpose
The response to neoadjuvant chemoradiotherapy (CRT) for rectal cancer can be assessed using digital rectal examination, endoscopy and magnetic resonance imaging (MRI). Precise assessment of clinical complete response (CR) after CRT is essential when deciding between optimizing surgery or organ-preserving treatment. The objectives of this study were to correlate the CR finding in endoscopy and MRI with pathologic CR and to determine the appropriate approach for combining endoscopy and MRI to predict the pathologic CR in patients with rectal cancer after neoadjuvant CRT.
Methods
This retrospective cohort study included 102 patients with rectal cancer who underwent endoscopy and MRI at 2–4 weeks after CRT. We assigned a confidence level (1–4) for the endoscopic and MRI assessments. Accuracy, sensitivity, and specificity were analyzed based on the endoscopy, MRI, and combination method findings. Diagnostic modalities were compared using the likelihood ratios.
Results
Of 102 patients, 17 (16.7%) had a CR. The accuracy, sensitivity, and specificity for the prediction CR of endoscopy with biopsy were 85.3%, 52.9%, and 91.8%, while those of MRI were 91.2%, 70.6%, and 95.3%, and those of combined endoscopy and MRI were 89.2%, 52.9%, and 96.5%, respectively. No significant differences were noted in the sensitivity and specificity of any each modality. The prediction rate for CR of the combination method was 92.6% after the posttest probability test.
Conclusion
Our study demonstrated that combining the interpretation of endoscopy with biopsy and MRI could provide a good prediction rate for CR in patients with rectal cancer after CRT.

Citations

Citations to this article as recorded by  
  • Assessing Endoscopic Response in Locally Advanced Rectal Cancer Treated with Total Neoadjuvant Therapy: Development and Validation of a Highly Accurate Convolutional Neural Network
    Hannah Williams, Hannah M. Thompson, Christina Lee, Aneesh Rangnekar, Jorge T. Gomez, Maria Widmar, Iris H. Wei, Emmanouil P. Pappou, Garrett M. Nash, Martin R. Weiser, Philip B. Paty, J. Joshua Smith, Harini Veeraraghavan, Julio Garcia-Aguilar
    Annals of Surgical Oncology.2024; 31(10): 6443.     CrossRef
  • Transanal endoscopic microsurgery after radiation or chemoradiation therapy for rectal cancer — peculiarities and results
    A А. Nevolskikh, A. R. Brodskiy, V. A. Avdeenko, T. P. Pochuev, Yu. Yu. Mihaleva, T. P. Berezovskaya, R. F. Zibirov, S. A. Myalina, I. A. Orehov, L. O. Petrov, S. A. Ivanov, A. D. Kaprin
    Koloproktologia.2024; 23(1): 82.     CrossRef
  • Diagnostic performance of MRI and endoscopy for assessing complete response in rectal cancer after neoadjuvant chemoradiotherapy: a systematic review of the literature
    Nicolai Egholt Munk, Peter Bondeven, Bodil Ginnerup Pedersen
    Acta Radiologica.2023; 64(1): 20.     CrossRef
  • Correlation of Tumor Response Between Flexible Sigmoidoscopy and Magnetic Resonance Imaging in Patients Undergoing Neoadjuvant Therapy for Locally Advanced Rectal Cancer: A Retrospective Review
    Maria A. Rojas, Jose Cataneo, Marianne Gagnon-Konamna, Daniel J. Borsuk, Angela J. Jarzabek, Slawomir J. Marecik, John J. Park, Kunal Kochar
    The American Surgeon™.2023; 89(6): 2595.     CrossRef
  • Endoscopy and MRI for restaging early rectal cancer after neoadjuvant treatment
    Rutger C. H. Stijns, Jeroen Leijtens, Eelco de Graaf, Simon P. Bach, Geerard Beets, Andre J. A. Bremers, Regina G. H. Beets‐Tan, Johannes H. W. de Wilt
    Colorectal Disease.2023; 25(2): 211.     CrossRef
  • Deep learning of endoscopic features for the assessment of neoadjuvant therapy response in locally advanced rectal cancer
    Anqi Wang, Jieli Zhou, Gang Wang, Beibei Zhang, Hongyi Xin, Haiyang Zhou
    Asian Journal of Surgery.2023; 46(9): 3568.     CrossRef
  • MRI Evaluation of Complete and Near-Complete Response after Neoadjuvant Therapy in Patients with Locally Advanced Rectal Cancer
    Anca-Raluca Popita, Cosmin Lisencu, Adriana Rusu, Cristian Popita, Calin Cainap, Alexandru Irimie, Liliana Resiga, Alina Munteanu, Zsolt Fekete, Radu Badea
    Diagnostics.2022; 12(4): 921.     CrossRef
  • Watch and wait strategies for rectal cancer: A systematic review
    In Ja Park
    Precision and Future Medicine.2022; 6(2): 91.     CrossRef
  • Early conformational changes at tumour bed and long term response after neoadjuvant therapy in locally-advanced rectal cancer
    Inês Santiago, Maria-João Barata, Nuno Figueiredo, Oriol Parés, Celso Matos
    European Journal of Radiology.2021; 140: 109742.     CrossRef
  • Improvement in the Assessment of Response to Preoperative Chemoradiotherapy for Rectal Cancer Using Magnetic Resonance Imaging and a Multigene Biomarker
    Eunhae Cho, Sung Woo Jung, In Ja Park, Jong Keon Jang, Seong Ho Park, Seung-Mo Hong, Jong Lyul Lee, Chan Wook Kim, Yong Sik Yoon, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
    Cancers.2021; 13(14): 3480.     CrossRef
  • High-Resolution T2-Weighted MRI to Evaluate Rectal Cancer: Why Variations Matter
    Kirsten L Gormly
    Korean Journal of Radiology.2021; 22(9): 1475.     CrossRef
  • Comparison between Local Excision and Radical Resection for the Treatment of Rectal Cancer in ypT0-1 Patients: An Analysis of the Clinicopathological Factors and Survival Rates
    Soo Young Oh, In Ja Park, Young IL Kim, Jong-Lyul Lee, Chan Wook Kim, Yong Sik Yoon, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
    Cancers.2021; 13(19): 4823.     CrossRef
  • MRI T2-weighted sequences-based texture analysis (TA) as a predictor of response to neoadjuvant chemo-radiotherapy (nCRT) in patients with locally advanced rectal cancer (LARC)
    Filippo Crimì, Giulia Capelli, Gaya Spolverato, Quoc Riccardo Bao, Anna Florio, Sebastiano Milite Rossi, Diego Cecchin, Laura Albertoni, Cristina Campi, Salvatore Pucciarelli, Roberto Stramare
    La radiologia medica.2020; 125(12): 1216.     CrossRef
  • MRI Assessment of Complete Response to Preoperative Chemoradiation Therapy for Rectal Cancer: 2020 Guide for Practice from the Korean Society of Abdominal Radiology
    Seong Ho Park, Seung Hyun Cho, Sang Hyun Choi, Jong Keon Jang, Min Ju Kim, Seung Ho Kim, Joon Seok Lim, Sung Kyoung Moon, Ji Hoon Park, Nieun Seo
    Korean Journal of Radiology.2020; 21(7): 812.     CrossRef
  • Watch and wait approach in rectal cancer: Current controversies and future directions
    Fernando López-Campos, Margarita Martín-Martín, Roberto Fornell-Pérez, Juan Carlos García-Pérez, Javier Die-Trill, Raquel Fuentes-Mateos, Sergio López-Durán, José Domínguez-Rullán, Reyes Ferreiro, Alejandro Riquelme-Oliveira, Asunción Hervás-Morón, Felipe
    World Journal of Gastroenterology.2020; 26(29): 4218.     CrossRef
Case Report
Colorectal Perforation After Anorectal Manometry for Low Anterior Resection Syndrome
Kyung Ha Lee, Ji Yeon Kim, Young Hoon Sul
Ann Coloproctol. 2017;33(4):146-149.   Published online August 31, 2017
DOI: https://doi.org/10.3393/ac.2017.33.4.146
  • 4,293 View
  • 71 Download
  • 6 Web of Science
  • 5 Citations
AbstractAbstract PDF

We experienced 3 cases of manometry-induced colon perforation. A 75-year-old man (case 1) underwent anorectal manometry (ARM) 3 years after radiotherapy for prostate cancer and a laparoscopic intersphincteric resection for rectal cancer. A 70-year-old man (case 2) underwent ARM 3 months after conventional neoadjuvant chemoradiotherapy and a laparoscopic low anterior resection for rectal cancer. A 78-year-old man (case 3) underwent ARM 2 months after a laparoscopic intersphincteric resection for rectal cancer. In all cases, a colon perforation with fecal peritonitis occurred. All were treated successfully using prompt and active operations and were discharged without any complications. ARM with a balloon, as a measure of rectal compliance, should be performed 2 months or longer after surgery. If a perforation occurs, prompt and active surgical intervention is necessary due to the high possibility of extensive fecal peritonitis.

Citations

Citations to this article as recorded by  
  • Effect of low anterior resection syndrome on quality of life in colorectal cancer patients: A retrospective observational study
    Dong-Ai Jin, Fang-Ping Gu, Tao-Li Meng, Xuan-Xuan Zhang
    World Journal of Gastrointestinal Surgery.2023; 15(10): 2123.     CrossRef
  • Functional anorectal studies in patients with low anterior resection syndrome
    Ssu‐Chi Chen, Kaori Futaba, Wing Wa Leung, Cherry Wong, Tony Mak, Simon Ng, Hans Gregersen
    Neurogastroenterology & Motility.2022;[Epub]     CrossRef
  • Variation in rectoanal inhibitory reflex after laparoscopic intersphincteric resection for ultralow rectal cancer
    Bin Zhang, Ke Zhao, Yu‐Juan Zhao, Shu‐Hui Yin, Guang‐Zuan Zhuo, Yong Zhao, Jian‐Hua Ding
    Colorectal Disease.2021; 23(2): 424.     CrossRef
  • Broken beer bottle as a cause of sigmoid perforation: A summary of causes and predictors in the management of traumatic and non-traumatic colorectal perforation
    Christian German Ospina-Pérez, Ana Milena Álvarez-Acuña, Lina María López-Álvarez, Rosa María Ospina-Pérez, Ivan David Lozada-Martínez, Sabrina Rahman
    International Journal of Surgery Case Reports.2021; 85: 106261.     CrossRef
  • Assessment of defecation function after sphincter-saving resection for mid to low rectal cancer: A cross-sectional study
    Bao-Jia Luo, Mei-Chun Zheng, Yang Xia, Zhu Ying, Jian-Hong Peng, Li-Ren Li, Zhi-Zhong Pan, Hui-Ying Qin
    European Journal of Oncology Nursing.2021; 55: 102059.     CrossRef
Editorial
Current Situation on the Diagnosis of Anismus-Discordances Between Imaging and a Physiologic Study
Kyung Ha Lee, Ji Yeon Kim
Ann Coloproctol. 2016;32(5):159-159.   Published online October 31, 2016
DOI: https://doi.org/10.3393/ac.2016.32.5.159
  • 2,621 View
  • 39 Download
  • 1 Web of Science
  • 1 Citations
PDF

Citations

Citations to this article as recorded by  
  • Systematic review and meta‐analysis of the outcome of puborectalis division in the treatment of anismus
    Sameh Hany Emile, Samer Hani Barsom, Sualeh Muslim Khan, Steven D. Wexner
    Colorectal Disease.2022; 24(4): 369.     CrossRef
Case Report
TisN0M1 Sigmoid Colon Cancer: A Case Report
Kyung Ha Lee, Jin Su Kim, Kwang Sik Cheon, In Sang Song, Dae Young Kang, Ji Yeon Kim
Ann Coloproctol. 2014;30(3):141-146.   Published online June 23, 2014
DOI: https://doi.org/10.3393/ac.2014.30.3.141
  • 4,395 View
  • 66 Download
  • 10 Web of Science
  • 8 Citations
AbstractAbstract PDF

Distant metastasis of a colon carcinoma in situ has not yet been reported. We experienced a case of a sigmoid colon carcinoma in situ with common hepatic lymph node metastasis. After the first operation, we diagnosed dual intramucosal adenocarcinomas of the sigmoid colon without any regional lymph node metastasis. After the second operation, a metastatic adenocarcinoma was found in the common hepatic lymph nodes. We suggest that metastasis in cases of a colonic carcinoma in situ is rare, but possible. The parallel progression model of tumors can explain this early metastasis.

Citations

Citations to this article as recorded by  
  • Potential for Metastasis and Recurrence in Colorectal Carcinoma In Situ: A Retrospective Analysis of 1069 Patients
    Seijong Kim, Jung Kyong Shin, Yoonah Park, Jung Wook Huh, Hee Cheol Kim, Seong Hyeon Yun, Woo Yong Lee, Yong Beom Cho
    Clinical Colorectal Cancer.2024; 23(3): 245.     CrossRef
  • Rectal intramucosal carcinoma with lymph node metastasis and tumor deposit
    Wenhao Chen, Liang Kang, Yan Huang, Zhao Ding
    Asian Journal of Surgery.2022; 45(9): 1719.     CrossRef
  • Presacral lymph node recurrence of rectal intramucosal adenocarcinoma after endoscopic mucosal resection: a case report
    Taichi Horino, Yukiharu Hiyoshi, Yuji Miyamoto, Naoya Yoshida, Hideo Baba
    Surgical Case Reports.2020;[Epub]     CrossRef
  • Recurrence, death risk, and related factors in patients with stage 0 colorectal cancer
    Ming-Hao Hsieh, Pei-Tseng Kung, Wen-Yin Kuo, Tao-Wei Ke, Wen-Chen Tsai
    Medicine.2020; 99(36): e21688.     CrossRef
  • Recurrence rate of lateral margin-positive cases after en bloc endoscopic submucosal dissection of colorectal neoplasia
    Seohyun Lee, Jihun Kim, Jae Seung Soh, Jungho Bae, Sung Wook Hwang, Sang Hyoung Park, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Dong-Hoon Yang
    International Journal of Colorectal Disease.2018; 33(6): 735.     CrossRef
  • Unusual Local Recurrence with Distant Metastasis after Successful Endoscopic Submucosal Dissection for Colorectal Mucosal Cancer
    Hyo Jeong Lee, Byong Duk Ye, Jeong-Sik Byeon, Jihun Kim, Young Soo Park, Yong Sang Hong, Yong Sik Yoon, Dong-Hoon Yang
    Clinical Endoscopy.2017; 50(1): 91.     CrossRef
  • Lymph node pooling: a feasible and efficient method of lymph node molecular staging in colorectal carcinoma
    Natalia Rakislova, Carla Montironi, Iban Aldecoa, Eva Fernandez, Josep Antoni Bombi, Mireya Jimeno, Francesc Balaguer, Maria Pellise, Antoni Castells, Miriam Cuatrecasas
    Journal of Translational Medicine.2017;[Epub]     CrossRef
  • Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis
    Akihiro Kogita, Yasumasa Yoshioka, Kazuko Sakai, Yosuke Togashi, Shunsuke Sogabe, Takuya Nakai, Kiyotaka Okuno, Kazuto Nishio
    Biochemical and Biophysical Research Communications.2015; 458(1): 52.     CrossRef
Original Article
A Phase II Study of Additional Four-Week Chemotherapy With Capecitabine During the Resting Periods After Six-Week Neoadjuvant Chemoradiotherapy in Patients With Locally Advanced Rectal Cancer
Kyung Ha Lee, Min Sang Song, Jun Boem Park, Jin Soo Kim, Dae Young Kang, Ji Yeon Kim
Ann Coloproctol. 2013;29(5):192-197.   Published online October 31, 2013
DOI: https://doi.org/10.3393/ac.2013.29.5.192
  • 3,103 View
  • 35 Download
  • 5 Citations
AbstractAbstract PDF
Purpose

The aim of this study is to evaluate the efficacy and the safety of additional 4-week chemotherapy with capecitabine during the resting periods after a 6-week neoadjuvant chemoradiotherapy (NCRT) in patients with locally advanced rectal cancer.

Methods

Radiotherapy was delivered to the whole pelvis at a total dose of 50.4 Gy for 6 weeks. Oral capecitabine was administered at a dose of 825 mg/m2 twice daily for 10 weeks. Surgery was performed 2-4 weeks following the completion of chemotherapy.

Results

Between January 2010 and September 2011, 44 patients were enrolled. Forty-three patients underwent surgery, and 41 patients completed the scheduled treatment. Pathologic complete remission (pCR) was noted in 9 patients (20.9%). T down-staging and N down-staging were observed in 32 patients (74.4%) and 33 patients (76.7%), respectively. Grade 3 to 5 toxicity was noted in 5 patients (11.4%). The pCR rate was similar with the pCR rates obtained after conventional NCRT at our institute and at other institutes.

Conclusion

This study showed that additional 4-week chemotherapy with capecitabine during the resting periods after 6-week NCRT was safe, but it was no more effective than conventional NCRT.

Citations

Citations to this article as recorded by  
  • Locally Advanced Rectal Cancer: What We Learned in the Last Two Decades and the Future Perspectives
    Vivek Srivastava, Aakansha Giri Goswami, Somprakas Basu, Vijay Kumar Shukla
    Journal of Gastrointestinal Cancer.2023; 54(1): 188.     CrossRef
  • The Effect of Continuing Chemotherapy after Chemoradiotherapy during the Time to Surgery on Tumor Response and Survival for Local Advanced Rectal Cancer
    Atike Gökçen Demiray, Arzu Yaren, Uğur Sungurtekin, Papatya Bahar Baltalarlı, Neşe Demirkan, Duygu Herek, Burcu Yapar Taşköylü, Gamze Gököz Doğu, Serkan Değirmencioğlu, Utku Özgen, Halil Sağınç, Umut Çakıroğlu, Nail Özhan, Canan Karan, Burçin Çakan Demire
    Journal of Oncology.2022; 2022: 1.     CrossRef
  • Phase 2 Neoadjuvant Treatment Intensification Trials in Rectal Cancer: A Systematic Review
    Mark T.W. Teo, Lucy McParland, Ane L. Appelt, David Sebag-Montefiore
    International Journal of Radiation Oncology*Biology*Physics.2018; 100(1): 146.     CrossRef
  • Efficacy and Safety of Low-Dose-Rate Endorectal Brachytherapy as a Boost to Neoadjuvant Chemoradiation in the Treatment of Locally Advanced Distal Rectal Cancer: A Phase-II Clinical Trial
    Shapour Omidvari, Shadi Zohourinia, Mansour Ansari, Leila Ghahramani, Mohammad Zare-Bandamiri, Ahmad Mosalaei, Niloofar Ahmadloo, Saeedeh Pourahmad, Hamid Nasrolahi, Sayed Hasan Hamedi, Mohammad Mohammadianpanah
    Annals of Coloproctology.2015; 31(4): 123.     CrossRef
  • Additional Chemotherapy During Resting Periods After Preoperative Chemoradiotherapy in Patients With Rectal Cancer
    Ok Suk Bae
    Annals of Coloproctology.2013; 29(5): 178.     CrossRef
  • FirstFirst
  • PrevPrev
  • Page of 1
  • Next Next
  • Last Last

Ann Coloproctol : Annals of Coloproctology Twitter Facebook
TOP