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Case Report
Benign GI diease,Rare disease & stoma
- McKittrick-Wheelock Syndrome: A Case Series
- Maureen Elvira P. Villanueva, Mark Augustine S. Onglao, Mayou Martin T. Tampo, Marc Paul J. Lopez
- Ann Coloproctol. 2022;38(3):266-270. Published online July 13, 2021
- DOI: https://doi.org/10.3393/ac.2020.00745.0106
- 6,476 View
- 212 Download
- 7 Web of Science
- 9 Citations
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Abstract
PDF - McKittrick-Wheelock syndrome is a rare and life-threatening disease characterized by the triad of (1) chronic mucous diarrhea, (2) renal function impairment with hydroelectrolyte imbalance, and (3) a giant colorectal tumor. Often, the tumor is a rectal adenoma. With the mortality being certain, if left untreated, it is important to raise awareness on the presentation, diagnosis, and management of this disease entity. Here, we presented 3 cases of McKittrick-Wheelock syndrome that were successfully managed with surgical resection at the Philippine General Hospital from August 2018 to May 2019. Resolution of their symptoms, reversal of their renal impairment, and correction of their electrolyte depletion were noted after removal of the tumor with a sphincter-saving operation.
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Citations
Citations to this article as recorded by
- Renal failure due to rectal neoplastic polyp: McKittrick–Wheelock syndrome—a case report
Ivan Valentinov Dimitrov, Theophil Angelov Sedloev, Ivan Petrov Vasilev, Slavyana Slavcheva Usheva, Yavor Asenov Nikolov, Nikolay Metodiev Penkov, Plamen Ivanov Penchev, Maria-Elena Boyadzhieva, Georgi Chavdarov Jelev
Journal of Medical Case Reports.2025;[Epub] CrossRef - A New Perspective on the Management of Giant Rectal Polyps Presenting With McKittrick-Wheelock Syndrome: A Case Report on Treatment With Transanal Excision and Delorme’s Plication
Andrew C Ekwesianya, Abraham V Jesudoss, Manoj Jacob, Mohamad F Badr, Bandipalyam V Praveen
Cureus.2025;[Epub] CrossRef - Surgical Treatment of a Severe Electrolyte Imbalance: A Case Report of an Elderly Patient With McKittrick–Wheelock Syndrome
Piotr Roman Więckowski, Joanna Matylda Łysak, Jakub Blicharz, Maciej Dudziński, Piotr Sienkiewicz, Muthukumaran Rangarajan
Case Reports in Surgery.2025;[Epub] CrossRef - McKittrick–Wheelock Syndrome, a Rare Cause of Nonresponsive Persistent Dyselectrolytemia
Daniela Cana Ruiu, Mihaela Cheie, Mirela Marinela Florescu, Andreea Doriana Stanculescu, Carmen Popescu, Daniela-Teodora Maria, Sebastian Constantin Toma, Naomi Fota, Daniela Calina, Bogdan Silviu Ungureanu
Diagnostics.2025; 15(19): 2459. CrossRef - Mckittrick-Wheelock syndrome as a rare manifestation of villous adenoma of the rectum
V.E. Khoronenko, V.S. Trifanov, N.V. Chebotareva, M.Yu. Meshcheryakova, M.V. Kosogolov
Pirogov Russian Journal of Surgery.2024; (3): 76. CrossRef - McKittrick–Wheelock Syndrome: A Case Report
Kristina Marcinkevičiūtė, Marius Kryžauskas, Tomas Poškus
Medicina.2023; 59(3): 633. CrossRef - Rapid Malignant Transformation of Tubulovillous Adenoma, Initially Presenting as McKittrick-Wheelock Syndrome: A Case Report
Ibnu Purwanto, Benedreky Leo, Bambang Purwanto Utomo, Imam Sofii, Ery Kus Dwianingsih, Neneng Ratnasari
Case Reports in Oncology.2023; 16(1): 818. CrossRef - Giant Villous Adenoma of the Rectum With Prolapse: Case Report
Iurii Munteanu, Munteanu Mihaela, Silvia Popescu, Iulian M Slavu, Anca Oprescu Macovei, Daniel Cochior
Cureus.2023;[Epub] CrossRef - Chronic Kidney Disease, Hypokalemia, and Appendicular Mucocele in a 66-Year-Old Man
Sanda Mrabet, Yosr Chaabouni, Mohamed Ben Hmida
American Journal of Men's Health.2022;[Epub] CrossRef
- Renal failure due to rectal neoplastic polyp: McKittrick–Wheelock syndrome—a case report
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