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Comparison of Limberg Flap and Karydakis Flap Surgery for the Treatment of Patients With Pilonidal Sinus Disease: A Single-Blinded Parallel Randomized Study
Mina Alvandipour, Mohammad Sadegh Zamani, Mojtaba Ghorbani, Jamshid Yazdani Charati, Mohammad Yasin Karami
Ann Coloproctol. 2019;35(6):313-318.   Published online May 22, 2019
DOI: https://doi.org/10.3393/ac.2018.09.27
  • 19,448 View
  • 270 Download
  • 17 Web of Science
  • 26 Citations
AbstractAbstract PDF
Purpose
Pilonidal sinus disease is a common condition, which mostly affects young men. While various surgical techniques have been introduced for treating intergluteal pilonidal disease (IPD), controversies still exist regarding the best surgical approach. The purpose of this study was to compare the efficiency and the short-term outcomes of Limberg flap and Karydakis flap surgeries for the treatments of patients with IPD.
Methods
A total of 80 patients with IPD who had underwent either Karydakis flap (KF group: n = 37) or Limberg flap (LF group: n = 27) surgery between January 2015 and January 2016 at Imam Khomeini Hospital of Sari in the North of Iran were recruited for inclusion in this randomized, single-blind study.
Results
Compared to the KF group, the LF group showed faster complete wound healing, longer duration of surgery and hospital stay, larger wound size, and shorter period of incapacity for work. The overall patient satisfaction in the LF group was significantly higher than that in the KF group. The visual analogue scale score of pain was lower in the LF group than in the KF group. Also, the overall frequency of postoperative complications was higher in the KF group than in the LF group. Recurrence was reported in one patient from the KF group.
Conclusion
Given the lower rate of postoperative complications and greater cosmetic satisfaction of patients, the Limberg flap procedure should be selected, instead of the Karydakis flap procedure, as the standard technique for treating patients with IPD.

Citations

Citations to this article as recorded by  
  • Light-based Epilation as an Adjunct to Surgery in the Management of Pilonidal Disease: A Meta-analysis
    Mody Kutkut, Ibrahim Khansa
    Plastic and Reconstructive Surgery - Global Open.2026; 14(1): e7364.     CrossRef
  • Short-term results of unroofing and marsupialization compared to the Karydakis technique in the treatment of pilonidal sinus. A randomized prospective study
    Pedro Antonio Parra Baños, Nuria Martínez Sanz, Francisco Miguel González Valverde, Jorge Alejandro Benavides Buleje, Miguel Ruiz Marín, Emilio Peña Ros, Carmen Martínez Sanz, Mari Fe Candel Arenas
    Cirugía Española (English Edition).2025; 103(1): 25.     CrossRef
  • Resultados a corto plazo de la puesta a plano, curetaje y marsupialización frente a la técnica de Karydakis en el tratamiento del seno pilonidal. Estudio prospectivo aleatorizado
    Pedro Antonio Parra Baños, Nuria Martínez Sanz, Francisco Miguel González Valverde, Jorge Alejandro Benavides Buleje, Miguel Ruiz Marín, Emilio Peña Ros, Carmen Martínez Sanz, Mari Fe Candel Arenas
    Cirugía Española.2025; 103(1): 25.     CrossRef
  • Langzeitergebnisse einer Pilotstudie über das zweizeitige Verfahren mit primärer Exzision und Limberg-Plastik im Intervall zur Therapie einer sakrokokzygealen Pilonidalsinuserkrankung
    Michael Ardelt, Falk Rauchfuss, Felix Dondorf, Aladdin Ali Deeb, Astrid Bauschke, Oliver Rohland, Laura Schwenk, Utz Settmacher
    Die Chirurgie.2025; 96(8): 667.     CrossRef
  • Outcome After Surgical Treatment for Chronic Pilonidal Sinus Disease: A Systematic Review of Common Surgical Techniques
    Ida-Marie Myron Wiinblad, Johan Ulrichsen, Birgitte Brandstrup
    Diseases of the Colon & Rectum.2025; 68(5): 515.     CrossRef
  • Ovine Forestomach Matrix Graft Reduces Surgical Dehiscence in Fasciocutaneous Flap-Based Closure of Pilonidal Disease: A Comparative Study
    Yosef Nasseri, Kimberly Oka, Kristina La, Rachel Ma, Christopher Frampton, Jessica Simon, Adam Young, Moshe Barnajian
    Cureus.2025;[Epub]     CrossRef
  • Midline and off-midline wound closure methods after surgical treatment for pilonidal sinus
    Zhaolun Cai, Zhou Zhao, Qin Ma, Chaoyong Shen, Zhiyuan Jiang, Chunyu Liu, Chunjuan Liu, Bo Zhang
    Cochrane Database of Systematic Reviews.2024;[Epub]     CrossRef
  • A new method for wound defect closure after pilonidal sinus excision
    E. N. Shubrov, A G. Baryshev, K. V. Triandafilov
    Koloproktologia.2024; 23(1): 129.     CrossRef
  • The application of ERAS in pilonidal sinus: comparison of postoperative recovery between primary suture and Limberg flap procedure in a multicenter prospective randomized trial
    Wei Lu, Shujuan Huang, Hui Ye, Shang Xiang, Xiangsheng Zeng
    Frontiers in Surgery.2024;[Epub]     CrossRef
  • Management and outcomes of pilonidal patients with secondary sinuses—a cohort study
    Norah E. Liang, Claire Abrajano, Kyla Santos Dalusag, Bill Chiu
    Pediatric Surgery International.2024;[Epub]     CrossRef
  • Dutch national guideline on the management of intergluteal pilonidal sinus disease
    Eleonora A Huurman, Christel A L de Raaff, Pim C E J Sloots, Oren Lapid, Hessel H van der Zee, Wilfred Bötger, Sandra Janssen, Francine Das, Andrea L J Kortlever-van der Spek, Anja van der Hout, Bas P L Wijnhoven, Boudewijn R Toorenvliet, Robert M Smeenk
    British Journal of Surgery.2024;[Epub]     CrossRef
  • Comparison of Outcome between Limberg Flap and Karydakis Flap in Pilonidal Sinus Disease
    Madeeha Shahid, Muhammad Khalid, Nazia Qamar, Salman Zafar, Sadia Sundus, Abdul Rehman
    Pakistan Journal of Health Sciences.2024; : 174.     CrossRef
  • The application of the Limberg flap repair technique in the surgical treatment of pilonidal sinus disease
    Yaoyao Song, Yu Zang, Zequn Chen, Jianjun Li, Minhui Zhu, Hongjuan Zhu, Wanli Chu, Gang Liu, Chuan'an Shen
    International Wound Journal.2023; 20(6): 2241.     CrossRef
  • Management of Pilonidal Disease
    Lindsay A. Gil, Katherine J. Deans, Peter C. Minneci
    JAMA Surgery.2023; 158(8): 875.     CrossRef
  • Bilaterally parallel elliptic flap versus Karydakis flap in primary pilonidal sinus disease: a randomized controlled trial
    Umut Fırat Turan, Serdar Coban, Tezcan Akin, Huseyin Berkem, Bulent Cavit Yuksel, Sadettin Er
    International Journal of Colorectal Disease.2023;[Epub]     CrossRef
  • Evaluation of single center clinical experience in patients undergoing modified Limberg flap technique in pilonidal sinus disease
    Burak UÇANER, Şebnem ÇİMEN, Mehmet Zeki BULDANLI
    Journal of Medicine and Palliative Care.2023; 4(6): 694.     CrossRef
  • Comparative Study on Short-Term Outcome in Patients Undergoing Pilonidal Sinus Surgery in Tertiary Care
    Dakshay A. Chordia, A. P. Prem, Jameel Akhter, M. Muralidharan, A. Sathishkumar
    Indian Journal of Colo-Rectal Surgery.2023; 6(1): 4.     CrossRef
  • Analysis of the Outcomes of a New Method for Plastic Surgery for Postoperative Wound Of Sacrococcygeal Region after Excision of the Pilonidal Cyst: Randomized Trial.
    E. N. Shubrov, A. G. Baryshev, K. V. Triandafilov, V. A. Aladina, V. V. Fedyushkin, R. K. Amirova
    Kuban Scientific Medical Bulletin.2022; 29(5): 80.     CrossRef
  • Effectiveness and Feasibility of Limberg and Karydakis Flap in Recurrent and Complicated Pilonidal Sinus Disease
    Amr Abdel Hameed Elhiny, Doaa Ali Saad, Mohamed Sadek Farahat
    Indian Journal of Surgery.2021; 83(1): 55.     CrossRef
  • S3-Leitlinie: Sinus pilonidalis. 2. revidierte Fassung 2020
    A. Ommer, I. Iesalnieks, D. Doll
    coloproctology.2021; 43(S1): 25.     CrossRef
  • Pilonoidal Sinüs Tedavisinde Modifiye Limberg Flep Uygulaması Sonuçları
    Nizamettin KUTLUER, Nurullah AKSOY
    Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi.2021; 16(1): 68.     CrossRef
  • Pilonidal Sinus Disease: An Analysis of the Factors Affecting Recurrence
    Murat Kanlioz, Uğur Ekici, Faik Tatli, Turgay Karatas
    Advances in Skin & Wound Care.2021; 34(2): 81.     CrossRef
  • Karydakis procedure versus Limberg flap for treatment of pilonidal sinus: an updated meta-analysis of randomized controlled trials
    Sameh Hany Emile, Sualeh Muslim Khan, Samer Hani Barsom, Steven D Wexner
    International Journal of Colorectal Disease.2021; 36(7): 1421.     CrossRef
  • Evaluation of comma-shaped incision with a sacral flap in surgical treatment of pilonidal sinus
    MinaR.A.R. El Nahal, MohammedY.F. Aly, RagaiS Hanna, GamalA Makhlouf, GamalA Hameed Ahmed
    Journal of Current Medical Research and Practice.2020; 5(1): 46.     CrossRef
  • Surgical procedures in the pilonidal sinus disease: a systematic review and network meta-analysis
    Siwei Bi, Kaibo Sun, Shanshan Chen, Jun Gu
    Scientific Reports.2020;[Epub]     CrossRef
  • An effective minimal invasive method in pilonidal sinus surgery: Sinusotomy
    Önder KARABAY
    Archives of Clinical and Experimental Medicine.2019; 4(3): 138.     CrossRef
Effect of Hyperoxygenation During Surgery on Surgical Site Infection in Colorectal Surgery
Mina Alvandipour, Farzad Mokhtari-Esbuie, Afshin Gholipour Baradari, Abolfazl Firouzian, Mehdi Rezaie
Ann Coloproctol. 2019;35(1):9-14.   Published online February 28, 2019
DOI: https://doi.org/10.3393/ac.2018.01.16
  • 7,582 View
  • 134 Download
  • 13 Web of Science
  • 16 Citations
AbstractAbstract PDF
Purpose
Despite the use of different surgical methods, surgical site infection is still an important cause of mortality and morbidity in patients and imposes a considerable cost on the healthcare system. Administration of supplemental oxygen during surgery has been reported to reduce surgical site infection (SSI); however, that result is still controversial. This study was performed to evaluate the effect of hyperoxygenation during colorectal surgery on the incidence of wound infection.
Methods
This study was a prospective double-blind case-control study. The main aim of the study was to evaluate the effect of hyperoxygenation during colorectal surgery on the incidence of SSI. Also, secondary outcomes, such as atelectasis, pneumonia, respiratory failure, length of hospital stay, and required hospitalization in the intensive care unit were evaluated.
Results
SSI was recorded in 2 patients (2 of 40, 5%) in the hyperoxygenation group (FiO2 80%) and 6 patients (6 of 40, 15%) in the control group (FiO2 30%) (P < 0.05). Time of hospitalization was 6 ± 6.4 days in the hyperoxygenation group and 9.2 ± 2.4 days in the control group (P < 0.05).
Conclusion
This study showed a positive effect of hyperoxygenation in reducing SSI in colorectal surgery, especially surgery in an emergency setting. When the low risk, low cost, and effectiveness of this method in patients undergoing a laparotomy are considered, it is recommended for all patients undergoing colorectal surgery.

Citations

Citations to this article as recorded by  
  • Effects of high vs. low perioperative inspired oxygen fraction on length of hospital stay and postoperative complications: a systematic review, meta-analysis, and trial sequential analysis
    Mimi WU, Lanlan CHANG, Leying SUN, Zhao DAI, Jinhua BO, Xin XU
    Minerva Anestesiologica.2025;[Epub]     CrossRef
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    勇 肖
    Advances in Clinical Medicine.2025; 15(08): 1883.     CrossRef
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    Adel Elfeky, Yen-Fu Chen, Amy Grove, Keith Couper, Rachel Court, Sara Tomassini, Anna Wilson, Amy Hooper, Alexandra Buckle, Sharvari Vadeyar, Marion Thompson, Olalekan Uthman, Joyce Yeung
    Health Technology Assessment.2025; : 1.     CrossRef
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    Im OP.2024; 14(05): 236.     CrossRef
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    Benjamin D. Shogan, Jon D. Vogel, Bradley R. Davis, Deborah S. Keller, Jennifer M. Ayscue, Lindsey E. Goldstein, Daniel L. Feingold, Amy L. Lightner, Ian M. Paquette
    Diseases of the Colon & Rectum.2024; 67(11): 1368.     CrossRef
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    Yoann El Maleh, Charlotte Fasquel, Christophe Quesnel, Marc Garnier
    Scientific Reports.2023;[Epub]     CrossRef
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    Pernilla V. Stropnicky, Thomas Becker, Julius Pochhammer, Axel Kramer
    Allgemein- und Viszeralchirurgie up2date.2023; 17(04): 301.     CrossRef
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    Jae Hee Kuh, Woo-Seok Jung, Leerang Lim, Hae Kyung Yoo, Jae-Woo Ju, Ho-Jin Lee, Won Ho Kim
    Scientific Reports.2023;[Epub]     CrossRef
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    Journal of Infection and Chemotherapy.2022; 28(4): 510.     CrossRef
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Purse-String Versus Linear Conventional Skin Wound Closure of an Ileostomy: A Randomized Clinical Trial
Mina Alvandipour, Babak Gharedaghi, Hamed Khodabakhsh, Mohammad Yasin Karami
Ann Coloproctol. 2016;32(4):144-149.   Published online August 31, 2016
DOI: https://doi.org/10.3393/ac.2016.32.4.144
  • 8,316 View
  • 89 Download
  • 21 Web of Science
  • 25 Citations
AbstractAbstract PDF
Purpose

Infection is one of the most frequent complications that can occur after ileostomy closure. The incidence of wound infection depends on the skin closure technique, but there is no agreement on the perfect closure method for an ileostomy wound. The aim of this study was to evaluate the incidence of infection, the patient's approval, and the patient's pain between purse-string closure (PSC) and the usual linear closure (LC) of a stoma wound.

Methods

This randomized clinical trial enrolled 66 patients who underwent a stoma closure from February 2015 to May 2015 in Sari Emam Khomeini Hospital. Patients were divided into 2 groups according to the stoma closing method: the PSC group (n = 34) and the LC group (n = 32). The incidences of infection for the 2 groups were compared, and the patients' satisfaction and pain with the stoma were determined by using a questionnaire.

Results

Infection occurred in 1 of 34 PSC patients (2.9%) and in 7 of 32 LC patients (21.8%), and this difference was statistically significant (P = 0.021). Patients in the PSC group were more satisfied with the resulting wound scar and its cosmetic appearance at one month and three months after surgery (P = 0.043).

Conclusion

After stoma closure, PSC was associated with a significantly lower incidence of wound infection and greater patient satisfaction compared to LC. However, the healing period for patients who underwent PSC was longer than it was for those who underwent LC.

Citations

Citations to this article as recorded by  
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    Senbin Lin, Misha Mao, Rui Chen, Linnan Guo, Mengya Zhou, Jianhui Chen
    International Journal of Colorectal Disease.2026;[Epub]     CrossRef
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    Shahab Hajibandeh, Shahin Hajibandeh, Andrew Kennedy-Dalby, Sheik Rehman, Reza Arsalani Zadeh
    International Journal of Colorectal Disease.2018; 33(10): 1319.     CrossRef
  • LOOP ILEOSTOMY CLOSURE (review)
    I. S. Lantsov, A. I. Moskalev, O. I. Sushkov
    Koloproktologia.2018; (2): 102.     CrossRef
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    D. P. O’Leary, M. Carter, D. Wijewardene, M. Burton, D. Waldron, E. Condon, J. C. Coffey, C. Peirce
    Techniques in Coloproctology.2017; 21(11): 863.     CrossRef
Case Report
Incidentally Solitary, Synchronous, Metastatic Left Adrenal Mass From Colon Cancer
Mina Alvandipour, Mohammad Yasin Karami, Mehdi Khalvati, Hamed Khodabakhsh
Ann Coloproctol. 2016;32(2):79-82.   Published online April 30, 2016
DOI: https://doi.org/10.3393/ac.2016.32.2.79
  • 7,864 View
  • 50 Download
  • 2 Web of Science
  • 4 Citations
AbstractAbstract PDF

The authors report the case of a 63-year-old man who underwent an open adrenalectomy for a synchronous, malignant, metastatic left adrenal tumor and a total colectomy for T3N0M1 (stage 4) primary, malignant colon cancer. Two polypoid lesions, one measuring 40 mm × 30 mm × 30 mm and the other measuring 20 mm × 10 mm × 10 mm, were found in the ascending colon and rectosigmoid (RS) junction, respectively, and a synchronous, malignant, left adrenal gland lesion measuring 70 mm × 50 mm × 30 mm was incidentally found on abdominal computed tomography scan. Histological examination revealed a metastatic, necrotic adenocarcinoma of the left adrenal mass, an adenocarcinoma of the cecal mass, and an adenomatous polyp (tubulovillous type) of the smallest polypoid lesion in RS junction that had invaded deeply into the submucosal layer. The patient recovered uneventfully, and his condition is now stable, with no evidence of local recurrence or metastatic disease, 2 years after the surgery. To the best of our knowledge, only 25 cases of an adrenalectomy for treating metastatic adrenal gland tumors have been reported to date; physicians should be aware of the possibility of this event.

Citations

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