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1 "Paul Benfredj"
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Original Article
Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients
Jean-David Zeitoun, Pierre Blanchard, Nadia Fathallah, Paul Benfredj, Nicolas Lemarchand, Vincent de Parades
Ann Coloproctol. 2018;34(2):83-87.   Published online April 30, 2018
DOI: https://doi.org/10.3393/ac.2017.06.12
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  • 19 Web of Science
  • 19 Citations
AbstractAbstract PDF
Purpose
The surgical standard of care for patients with chronic anal fissure is still disputed. We aimed to assess the natural course of idiopathic anal fissure and the long-term outcome of a fissurectomy as a surgical treatment.
Methods
All consecutive patients referred to a single expert practitioner in a tertiary centre were primarily included. A fissurectomy was proposed in cases of refractory symptoms after 4 to 6 weeks of standard medical management. Only patients with idiopathic and noninfected anal fissures were included in this second subsample to undergo surgery. Conventional postoperative management was prescribed for all patients who had undergone surgery. The main outcome measures were the success rate (defined as a combination of wound healing and relief of pain) and postoperative anal continence.
Results
Three hundred forty-nine patients were primarily recruited. Fifty patients finally underwent surgery for an idiopathic and noninfected fissure. Among them, 47 (94%) were cured at the end of primary follow-up, and 44 of the 47 (93.6%) could be confirmed as being sustainably cured in the longer-term follow-up. The mean time of complete healing was 10.3 weeks (range, 5.7–36.4 weeks). All patients were free of pain at weeks 42. The continence score after surgery was not statistically different from the preoperative score.
Conclusion
A fissurectomy for the treatment of patients with an idiopathic noninfected fissure is associated with rapid pain relief and a high success rate even though complete healing may often be delayed. Moreover, it appears to have no adverse effect on continence.

Citations

Citations to this article as recorded by  
  • Belgian consensus guideline on the management of anal fissures
    P Roelandt, G Bislenghi, G Coremans, D De Looze, M.A. Denis, H De Schepper, P Dewint, J Geldof, I Gijsen, N Komen, H Ruymbeke, J Stijns, M Surmont, D Van de Putte, S Van den Broeck, B Van Geluwe, J Wyndaele
    Acta Gastro Enterologica Belgica.2024; 87(2): 304.     CrossRef
  • Use of Botulinum Toxin Injections for the Treatment of Chronic Anal Fissure: Results From an American Society of Colon and Rectal Surgeons Survey
    Daniel J. Borsuk, Adam Studniarek, John J. Park, Slawomir J. Marecik, Anders Mellgren, Kunal Kochar
    The American Surgeon™.2023; 89(3): 346.     CrossRef
  • New Findings at the Internal Anal Sphincter on Cadaveric Dissection and Review of Sphincter-Related Surgery in a Newer Prospective
    Aswini Kumar Pujahari
    Indian Journal of Surgery.2023; 85(3): 585.     CrossRef
  • Pelvic floor physical therapy in patients with chronic anal fissure: long-term follow-up of a randomized controlled trial
    Daniëlle A. van Reijn-Baggen, Henk W. Elzevier, H. Putter, Rob C. M. Pelger, Ingrid J. M. Han-Geurts
    International Journal of Colorectal Disease.2023;[Epub]     CrossRef
  • Fissurectomy with mucosal advancement flap anoplasty: The end of a dogma?
    M. Skoufou, J.H. Lefèvre, A. Fels, N. Fathallah, P. Benfredj, V. de Parades
    Journal of Visceral Surgery.2023; 160(5): 330.     CrossRef
  • Fissurectomy versus lateral internal sphincterotomy in the treatment of chronic anal fissures: no advantages in terms of post-operative incontinence
    Roberta Tutino, Casimiro Nigro, Flavia Paternostro, Rosa Federico, Giacomo Lo Secco, Gaetano Gallo, Mauro Santarelli, Gianfranco Cocorullo, Sebastiano Bonventre
    Techniques in Coloproctology.2023; 27(10): 885.     CrossRef
  • The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure
    Antonio Brillantino, Adolfo Renzi, Pasquale Talento, Francesca Iacobellis, Luigi Brusciano, Luigi Monaco, Domenico Izzo, Alfredo Giordano, Michele Pinto, Corrado Fantini, Marcello Gasparrini, Michele Schiano Di Visconte, Francesca Milazzo, Giovanni Ferrer
    BMC Surgery.2023;[Epub]     CrossRef
  • La fissurectomie avec anoplastie muqueuse : la fin d’un dogme ?
    Maria Skoufou, Jérémie H. Lefèvre, Audrey Fels, Nadia Fathallah, Paul Benfredj, Vincent de Parades
    Journal de Chirurgie Viscérale.2023; 160(5): 363.     CrossRef
  • Modified open posterior internal sphincterotomy with sliding skin graft for chronic anal fissure and anal stenosis: Low recurrence rate and no serious faecal incontinence postoperative complication
    Y. Iida, K. Honda, R. Iida, H. Saitou, Y. Munemoto, A. Tanaka, H. Tanaka
    Journal of Visceral Surgery.2022; 159(4): 267.     CrossRef
  • Sphinctérotomie interne postérieure modifiée avec un lambeau cutané pour fissure anale et sténose anale : peu de récidives et d’incontinence anale
    Y. Iida, K. Honda, R. Iida, H. Saitou, Y. Munemoto, A. Tanaka, H. Tanaka
    Journal de Chirurgie Viscérale.2022; 159(4): 283.     CrossRef
  • Injection of botulinum toxin significantly increases efficiency of fissurectomy in the treatment of chronic anal fissures
    Philip Roelandt, Georges Coremans, Jan Wyndaele
    International Journal of Colorectal Disease.2022; 37(2): 309.     CrossRef
  • Clinical Trial Combining Botulinum Toxin A Injection and Fissurectomy for Chronic Anal Fissure: A Dose-Dependent Study
    Nuha Alsaleh, Abdullah I. Aljunaydil, Gaida A. Aljamili
    Journal of Coloproctology.2022; 42(02): 167.     CrossRef
  • Fisurectomy and anoplasty with botulinum toxin injection in patients with chronic anal posterior fissure with hypertonia: a long-term evaluation
    Beatrice D’Orazio, Girolamo Geraci, Guido Martorana, Carmelo Sciumé, Giovanni Corbo, Gaetano Di Vita
    Updates in Surgery.2021; 73(4): 1575.     CrossRef
  • The comparison between the medical and the surgical management of chronic anal fissures
    Navneet Mishra, Kamal Kishore Parmar, Tanweerul Huda
    Journal of Clinical and Investigative Surgery.2021; 6(1): 11.     CrossRef
  • Anocutaneous advancement flap provides a quicker cure than fissurectomy in surgical treatment for chronic anal fissure—a retrospective, observational study
    Edgar Hancke, Katrin Suchan, Knut Voelke
    Langenbeck's Archives of Surgery.2021; 406(8): 2861.     CrossRef
  • Fissurectomy Versus Lateral Internal Sphincterotomy in the Treatment of Chronic Anal Fissure: A Randomized Control Trial
    Bipin Kishore Bara, Sujit Kumar Mohanty, Satya Narayan Behera, Ashok Kumar Sahoo, Santanu Kumar Swain
    Cureus.2021;[Epub]     CrossRef
  • Botulinum toxin associated with fissurectomy and anoplasty for hypertonic chronic anal fissure: A case-control study
    Beatrice D'Orazio, Girolamo Geraci, Fausto Famà, Gloria Terranova, Gaetano Di Vita
    World Journal of Clinical Cases.2021; 9(32): 9722.     CrossRef
  • Scanner-Assisted CO2 Laser Fissurectomy: A Pilot Study
    Iacopo Giani, Tommaso Cioppa, Chiara Linari, Filippo Caminati, Paolo Dreoni, Gianni Rossi, Cinzia Tanda, Giuseppina Talamo, Federico Bettazzi, Alessandra Aprile, Silvia Grassi, Antonella Pede, Luca Giannoni, Claudio Elbetti
    Frontiers in Surgery.2021;[Epub]     CrossRef
  • Fissurectomy combined with botulinum toxin A: a review of short- and long-term efficacy of this treatment strategy for chronic anal fissure; a consecutive proposal of a treatment algorithm for chronic anal fissure
    M. Trzpis, J. M. Klaase, R. H. Koop, P. M. A. Broens
    coloproctology.2020; 42(5): 400.     CrossRef
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