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Aluminum Potassium Sulfate and Tannic Acid Injection for Hemorrhoids
Seok Won Lim
J Korean Soc Coloproctol. 2012;28(2):73-77.   Published online April 30, 2012
DOI: https://doi.org/10.3393/jksc.2012.28.2.73
  • 43,742 View
  • 77 Download
  • 14 Citations
AbstractAbstract PDF

A quick hemostatic effect, as well as sclerosing and shrinkage of hemorrhoids, can be attained when internal hemorrhoids are treated by using injection therapy with aluminum potassium sulfate and tannic acid (ALTA), the outcomes of treatment may be similar to those of a hemorrhoidectomy. However, if the type of hemorrhoid or the method of injection is not appropriate for ALTA treatment, complications peculiar to ALTA or recurrence may develop. Accordingly, sufficient understanding of the treatment mechanism of ALTA injection and repeated training for injection are required for effective use of the ALTA treatment.

Citations

Citations to this article as recorded by  
  • Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy for hemorrhoidal disease: a systematic review and meta-analysis
    Vasiliki Manaki, Vangelis Bontinis, Alkis Bontinis, Argirios Giannopoulos, Ioannis Kontes, Angeliki Chorti, Kiriakos Ktenidis
    Acta Chirurgica Belgica.2024; 124(4): 253.     CrossRef
  • Efficacy and Safety of a New Technique Combining Injection Sclerotherapy and External Hemorrhoidectomy for Prolapsed Hemorrhoids: A Single-center Observational Study
    Tatsuya Abe, Masao Kunimoto, Yoshikazu Hachiro, Akane Ito, Kenji Watanabe, Shigenori Ota, Kei Ohara, Mitsuhiro Inagaki, Yusuke Saitoh, Masanori Murakami
    Journal of the Anus, Rectum and Colon.2024; 8(4): 331.     CrossRef
  • ANTI-HEMORRHOIDAL ACTIVITY OF AYURVEDIC CREAM IN RATS
    Anil T. Pawar, Chinmay D. Deshmukh, Digambar K. Jadhav, Ranganath R. Kulkarni
    INDIAN DRUGS.2023; 60(01): 84.     CrossRef
  • Injection of aluminum potassium sulfate and tannic acid in the treatment of fecal incontinence: a single-center observational study
    Tatsuya Abe, Masao Kunimoto, Yoshikazu Hachiro, Kei Ohara, Mitsuhiro Inagaki
    Annals of Coloproctology.2022; 38(6): 403.     CrossRef
  • Sklerosierungstherapie
    Alex Furtwängler
    coloproctology.2020; 42(1): 14.     CrossRef
  • Effectiveness of Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid as a Non-Surgical Treatment for Internal Hemorrhoids
    Yuichi Tomiki, Jun Aoki, Shunsuke Motegi, Rina Takahashi, Toshiaki Hagiwara, Yu Okazawa, Kosuke Mizukoshi, Masaya Kawai, Shinya Munakata, Shun Ishiyama, Kiichi Sugimoto, Kazuhiro Sakamoto
    Clinical Endoscopy.2019; 52(6): 581.     CrossRef
  • Taste of phytocompounds: A better predictor for ethnopharmacological activities of medicinal plants than the phytochemical class?
    Dorin Dragos, Marilena Gilca
    Journal of Ethnopharmacology.2018; 220: 129.     CrossRef
  • Changes in anorectal physiology following injection sclerotherapy using aluminum potassium sulfate and tannic acid versus transanal repair in patients with symptomatic rectocele; a retrospective cohort study
    Joo Hyung Kim, Yong Pyo Lee, Kwang Wook Suh
    BMC Surgery.2018;[Epub]     CrossRef
  • Extraoral Taste Receptor Discovery: New Light on Ayurvedic Pharmacology
    Marilena Gilca, Dorin Dragos, Marco Leonti
    Evidence-Based Complementary and Alternative Medicine.2017;[Epub]     CrossRef
  • Liver injury after aluminum potassium sulfate and tannic acid treatment of hemorrhoids
    Kenichi Yoshikawa, Reimi Kawashima, Yuki Hirose, Keiko Shibata, Takafumi Akasu, Noriko Hagiwara, Takeharu Yokota, Nami Imai, Akira Iwaku, Go Kobayashi, Hirohiko Kobayashi, Akiyoshi Kinoshita, Nao Fushiya, Hiroyuki Kijima, Kazuhiko Koike, Masayuki Saruta
    World Journal of Gastroenterology.2017; 23(27): 5034.     CrossRef
  • Treatment of Internal Hemorrhoids by Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid
    Yuichi Tomiki, Seigo Ono, Jun Aoki, Rina Takahashi, Shun Ishiyama, Kiichi Sugimoto, Yukihiro Yaginuma, Yutaka Kojima, Michitoshi Goto, Atsushi Okuzawa, Kazuhiro Sakamoto
    Diagnostic and Therapeutic Endoscopy.2015; 2015: 1.     CrossRef
  • Aluminum Potassium Sulfate and Tannic Acid - A New Option for the Treatment of Grade 3 Hemorrhoids
    Yong Hee Hwang
    Annals of Coloproctology.2015; 31(3): 83.     CrossRef
  • Comparison of Injection Sclerotherapy Between 5% Phenol in Almond Oil and Aluminum Potassium Sulfate and Tannic Acid for Grade 3 Hemorrhoids
    Takaaki Yano, Kenji Yano
    Annals of Coloproctology.2015; 31(3): 103.     CrossRef
  • Distal Hemorrhoidectomy With ALTA Injection: A New Method for Hemorrhoid Surgery
    Tatsuya Abe, Yoshikazu Hachiro, Yoshiaki Ebisawa, Houhei Hishiyama, Masao Kunimoto
    International Surgery.2014; 99(3): 295.     CrossRef
Original Article
Analysis of Delayed Postpolypectomy Bleeding in a Colorectal Clinic
Do Hyoung Kim, Seok Won Lim
J Korean Soc Coloproctol. 2011;27(1):13-16.   Published online February 28, 2011
DOI: https://doi.org/10.3393/jksc.2011.27.1.13
  • 4,566 View
  • 40 Download
  • 8 Citations
AbstractAbstract PDF
Purpose

The colonoscopic polypectomy has become a valuable procedure for removing precursors of colorectal cancer, but some complications can be occurred. The most common complication after colonoscopic polypectomy is bleeding, which is reported to range from 1% to 6% and which can be immediate or delayed. Because the management of delayed postpolypectomy bleeding could be difficult, the use of preventive technique and reductions of risk factors are essential.

Methods

From January 2007 to December 2008, delayed hemorrhage occurred in 18 of the 1,841 polypectomy patients examined by one endoscopist. These cases were reviewed retrospectively for risk factors, pathologic findings, and treatment methods.

Results

Delayed bleeding occurred in 18/1,841 patients (0.95%). The mean age was 55.9 ± 10.9 years, and the male-to-female ratio was 8:1. The most common site was the right colon (11 cases, 61.1%), and the average polyp size was 9.2 ± 2.8 mm. Delayed bleeding was identified from 1 to 5 days after resection (mean, 1.6 ± 1.2 days). The most common macroscopic type of polyp was a sessile polyp (10 cases, 55.6%), and histologic finding was a tubular adenoma in 13 cases (72.2%). Seventeen cases were treated with clipping for hemostasis and 1 case with epinephrine injection.

Conclusion

The right colon and a sessile polyp were associated with an increase in delayed postpolypectomy bleeding. Reducing risk factors and close observation were essential in high risk patients, and prompt management with hemoclips was effective.

Citations

Citations to this article as recorded by  
  • Delphi consensus statement for the management of delayed post-polypectomy bleeding
    Enrique Rodríguez de Santiago, Sandra Pérez de la Iglesia, Diego de Frutos, José Carlos Marín-Gabriel, Carolina Mangas-SanJuan, Raúl Honrubia López, Hugo Uchima, Marta Aicart-Ramos, Miguel Ángel Rodríguez Gandía, Eduardo Valdivielso Cortázar, Felipe Ramos
    Therapeutic Advances in Gastroenterology.2025;[Epub]     CrossRef
  • Real-world local recurrence rate after cold polypectomy in colorectal polyps less than 10 mm using propensity score matching
    Masashi Saito, Takeshi Yamamura, Masanao Nakamura, Keiko Maeda, Tsunaki Sawada, Eri Ishikawa, Yasuyuki Mizutani, Takuya Ishikawa, Naomi Kakushima, Kazuhiro Furukawa, Eizaburo Ohno, Hiroki Kawashima, Masatoshi Ishigami, Mitsuhiro Fujishiro
    World Journal of Gastroenterology.2021; 27(47): 8182.     CrossRef
  • Risk factors for delayed hemorrhage after colonoscopic postpolypectomy: Polyp size and operative modality
    Changqin Liu, Ruijin Wu, Xiaomin Sun, Chunhua Tao, Zhanju Liu
    JGH Open.2019; 3(1): 61.     CrossRef
  • Do We Perform a Perfect Endoscopic Hemostasis Prophylactically with Argon Plasma Coagulation in Colonic Endoscopic Mucosal Resection?
    Yunho Jung, Il Kwun Chung, Young Sin Cho, Tae Hoon Lee, Sang-Heum Park, Ji Sung Lee, Sun Joo Kim
    Digestive Diseases and Sciences.2015; 60(10): 3100.     CrossRef
  • Risk Factors for Delayed Post-Polypectomy Bleeding
    Min Jung Kwon, You Sun Kim, Song I Bae, Young Il Park, Kyung Jin Lee, Jung Hwa Min, Soo Yeon Jo, Mi Young Kim, Hye Jin Jung, Seong Yeon Jeong, Won Jae Yoon, Jin Nam Kim, Jeong Seop Moon
    Intestinal Research.2015; 13(2): 160.     CrossRef
  • Risk factors for delayed post‐polypectomy hemorrhage: A case‐control study
    Jeong Ho Kim, Hyun Jeong Lee, Ji Won Ahn, Dae Young Cheung, Jin Il Kim, Soo‐Heon Park, Jae Kwang Kim
    Journal of Gastroenterology and Hepatology.2013; 28(4): 645.     CrossRef
  • Serum C-reactive Protein As a Possible Marker to Predict Delayed Hemorrhage After Colonoscopic Polypectomy
    Liangqin Wu, Tiemei Han, Xiaoyuan Fan, Wensheng Pan, Chunfu Wang, Hua Zhong, Xinbo Ai, Wanjun Zhang, Xiang Xu, Zaiyuan Ye, Takesh Terai, Nobuhiro Sato, Sumio Watanabe, Undurti N. Das
    Medical Science Monitor.2012; 18(8): CR480.     CrossRef
  • Endoscopic mucosal resection with an over-the-counter hyaluronate preparation
    Shai Friedland, Shivangi Kothari, Ann Chen, Walter Park, Subhas Banerjee
    Gastrointestinal Endoscopy.2012; 75(5): 1040.     CrossRef
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