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1 "Tiago HM Vieira"
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Original Article
Morphine Spinal Block Anesthesia in Patients Who Undergo an Open Hemorrhoidectomy: A Prospective Analysis of Pain Control and Postoperative Complications
Hélio Moreira, José PT Moreira, Raniere R Isaac, Onofre Alves-Neto, Thiago AC Moreira, Tiago HM Vieira, Andressa MS Brasil
Ann Coloproctol. 2014;30(3):135-140.   Published online June 23, 2014
DOI: https://doi.org/10.3393/ac.2014.30.3.135
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  • 11 Web of Science
  • 12 Citations
AbstractAbstract PDF
Purpose

This study evaluated the use of adding morphine to bupivacaine in spinal anesthesia for pain control in patients who underwent an open hemorrhoidectomy.

Methods

Forty patients were prospectively selected for an open hemorrhoidectomy at the same institution and were randomized into two groups of 20 patients each: group 1 had a spinal with 7 mg of heavy bupivacaine associated with 80 µg of morphine (0.2 mg/mL). Group 2 had a spinal with 7 mg of heavy bupivacaine associated with distilled water, achieving the same volume of spinal infusion as that of group 1. Both groups were prescribed the same pain control medicine during the postoperative period. Pain scores were evaluated at the anesthetic recovery room and at 3, 6, 12, and 24 hours after surgery. Postoperative complications, including pruritus, nausea, headaches, and urinary retention, were also recorded.

Results

There were no anthropometric statistical differences between the two groups. Pain in the anesthetic recovery room and 3 hours after surgery was similar for both groups. However, pain was better controlled in group 1 at 6 and 12 hours after surgery. Although pain was better controlled for group 1 after 24 hours of surgery, the difference between the groups didn't achieved statistical significance. Complications were more common in group 1. Six patients (6/20) presented coetaneous pruritus and 3 with (3/20) urinary retention.

Conclusion

A hemorrhoidectomy under a spinal with morphine provides better pain control between 6 and 12 hours after surgery. However, postoperative complications, including cutaneous pruritus (30%) and urinary retention (15%), should be considered as a negative side of this procedure.

Citations

Citations to this article as recorded by  
  • Intradermal methylene blue analgesic application in posthemorrhoidectomy pain management: a randomized controlled trial
    Ramin Azhough, Pooya Jalali, Mohammad Reza Dashti, Sahar Taher, Ali Aghajani
    Frontiers in Surgery.2024;[Epub]     CrossRef
  • The effect of bupivacaine on analgesia and safety in patients undergoing hemorrhoidectomy: a meta-analysis
    Haixia Lu, Min Cai, Dongxi Zhou, Weiwei Li, Hanzhong Cao
    Frontiers in Pharmacology.2024;[Epub]     CrossRef
  • Non-pulmonary complications of intrathecal morphine administration: a systematic review and meta-analysis with meta-regression
    Yves Renard, Kariem El-Boghdadly, Jean-Benoît Rossel, Alexandre Nguyen, Cécile Jaques, Eric Albrecht
    British Journal of Anaesthesia.2024; 133(4): 823.     CrossRef
  • Ten-year multicentric retrospective analysis regarding postoperative complications and impact of comorbidities in hemorrhoidal surgery with literature review
    Cosmin Moldovan, Elena Rusu, Daniel Cochior, Madalina Elena Toba, Horia Mocanu, Razvan Adam, Mirela Rimbu, Adrian Ghenea, Florin Savulescu, Daniela Godoroja, Florin Botea
    World Journal of Clinical Cases.2023; 11(2): 366.     CrossRef
  • The Assessment of Marcaine Versus Meperidine for Spinal Anesthesia in Anorectal Surgery: A Randomized Clinical Trial
    Mehran Rezvani Habibabadi, Masumeh Safaee, Ali Rezaei
    Anesthesiology and Pain Medicine.2023;[Epub]     CrossRef
  • Strategies to Reduce Post-Hemorrhoidectomy Pain: A Systematic Review
    Varut Lohsiriwat, Romyen Jitmungngan
    Medicina.2022; 58(3): 418.     CrossRef
  • Non-Doppler hemorrhoidal artery ligation and hemorrhoidopexy combined with pudendal nerve block for the treatment of hemorrhoidal disease: a non-inferiority randomized controlled trial
    Konstantinos Perivoliotis, Michail Spyridakis, Elias Zintzaras, Eleni Arnaoutoglou, Manousos-Georgios Pramateftakis, Konstantinos Tepetes
    International Journal of Colorectal Disease.2021; 36(2): 353.     CrossRef
  • The effect of adding morphine to intratecal bupivacaine on postoperative analgesia in patients with perianal surgery
    Münire BABAYİĞİT
    Anatolian Current Medical Journal.2021; 3(2): 124.     CrossRef
  • Endogenous Opiates and Behavior: 2015
    Richard J. Bodnar
    Peptides.2017; 88: 126.     CrossRef
  • Evidence‐Based Management of Pain After Excisional Haemorrhoidectomy Surgery: A PROSPECT Review Update
    Tarik Sammour, Ahmed W. H. Barazanchi, Andrew G. Hill, Francis Bonnet, Barrie Fischer, Girish Joshi, Henrik Kehlet, Philipp Lirk, Narinder Rawal, Stephan Schug, Marc Van de Velde, Marcel Vercauteren
    World Journal of Surgery.2017; 41(2): 603.     CrossRef
  • Prolonged Opioid-Sparing Pain Control after Hemorrhoidectomy with Liposome Bupivacaine: Results from a Cohort of 95 Patients
    Allen B. Jetmore, Douglas Hagen
    Pain Studies and Treatment.2016; 04(01): 5.     CrossRef
  • Spinal Block Anesthesia With Morphine in a Hemorrhoidectomy
    Byung Chun Kim
    Annals of Coloproctology.2014; 30(3): 107.     CrossRef
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