Annals of Coloproctology

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Case Report

Colorectal cancer

Melanocytic nevus of the anal canal and granular cell tumor of the cecum: a case report and literature review of 2 coincidentally co-occurring neurocristopathies: Victoria Sandoval, Jorge Lara-Endara, Javier Rodríguez-Suárez, Williams Arias Garzón, Ligia Redrobán, Nelson Montalvo; Ann Coloproctol. 2024;40(Suppl 1):S23-S26. Published online January 12, 2023; DOI: https://doi.org/10.3393/ac.2022.00444.0063

Abstract PDF: Granular cell tumors are predominantly benign soft tissue tumors originating from Schwann cells, whereas melanocytic nevi are benign proliferations of melanocytes. We present the case of a patient with the presence of both entities located in the cecum and anal canal, respectively, constituting an extremely rare coincidental finding. A 43-year-old woman was evaluated by colonoscopy for iron-deficiency microcytic anemia that had lasted for 1 year. Colonoscopy demonstrated a macular lesion of 0.3 cm with a melanocytic appearance in the anal canal; at the cecum level, a subepithelial, yellowish, and partially mobile firm nodular lesion measuring 1.3 cm was observed. A histopathological study showed a melanocytic nevus in the anal canal and a granular cell tumor in the cecum. This is the first reported case of a patient with the extremely rare coincidental-incidental finding of these 2 entities at the same time.

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