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Colorectal cancer
The Korean Rectal Cancer Multidisciplinary Committee Clinical Practice Guidelines for Rectal Cancer version 2.0
Hyo Seon Ryu, Hyun Jung Kim, Dong Hyun Kang, Yoo-Kang Kwak, Han Deok Kwak, Yoon-Hye Kwon, Dalyong Kim, Baek-Hui Kim, Jae Hyun Kim, Ji Hun Kim, Jin Won Kim, Tae Hyung Kim, Hae Young Kim, Soo Min Nam, Gyoung Tae Noh, Jun Woo Bong, Nak Song Sung, Seon Hui Shin, Kil-Yong Lee, Sung Chul Lee, Sea-Won Lee, Jung Won Lee, Jong Min Lee, Myung Hoon Ihn, Joo Han Lim, Woong Bae Ji, Dae Hee Pyo, Young Ki Hong, Jung-Myun Kwak, on behalf of the Korean Rectal Cancer Multidisciplinary (KRCM) Committee
Ann Coloproctol. 2026;42(1):4-33.   Published online February 24, 2026
DOI: https://doi.org/10.3393/ac.2025.01396.0199
  • 1,731 View
  • 161 Download
AbstractAbstract PDFSupplementary Material
Rectal cancer, which accounts for approximately 40% of colorectal cancers, remains a major clinical concern. Recent advances in diagnostic imaging, surgical techniques, radiotherapy, and systemic treatment have steadily improved rectal cancer outcomes. Considering this, the Korean Rectal Cancer Multidisciplinary (KRCM) Committee has aimed to provide clinicians and policymakers with up-to-date, evidence-based clinical practice guidelines to support optimal decision-making, reflecting current evidence, the Korean healthcare context, and patient values and preferences. The Clinical Practice Guidelines for Rectal Cancer version 2.0 were developed through multidisciplinary collaboration with related academic societies, building upon and updating the KRCM Clinical Practice Guidelines version 1.0 (titled “Multidisciplinary guidelines for the management of rectal cancer”). These consensus guidelines of the KRCM were established based on a comprehensive literature review, evidence synthesis, with recommendation development guided by the GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology, and consideration of applicability in real-world clinical practice under the national health insurance system. Each recommendation has been presented with its strength and level of evidence.
Review
Colorectal cancer
Immunotherapy for microsatellite-stable colorectal cancer: overcoming resistance and exploring novel therapeutic strategies
Sun Young Kim
Ann Coloproctol. 2026;42(1):47-57.   Published online February 19, 2026
DOI: https://doi.org/10.3393/ac.2025.01354.0193
  • 1,751 View
  • 55 Download
  • 1 Citations
AbstractAbstract PDF
Microsatellite-stable (MSS) colorectal cancer (CRC), comprising 85% to 95% of all CRC cases, represents a significant therapeutic challenge in the era of cancer immunotherapy. Unlike microsatellite instability-high tumors that demonstrate remarkable responses to immune checkpoint inhibitors, MSS CRC exhibits profound resistance due to low tumor mutational burden, minimal T-cell infiltration, and an immunosuppressive tumor microenvironment. This article reviews the current landscape of immunotherapy trials in MSS CRC, including the recently reported STELLAR-303 study, discusses emerging predictive biomarkers such as tumor mutational burden, Immunoscore Immune Checkpoint (Immunoscore-IC), and artificial intelligence-driven tools like Lunit SCOPE, and explores innovative strategies to overcome immune resistance, including next-generation anti–cytotoxic T-lymphocyte–associated protein-4 (anti–CTLA-4) antibodies, programmed cell death-ligand 1 (PD-L1)/interleukin-2 (IL-2) bispecific antibodies, CD47-targeting strategies, vaccines, and chimeric antigen receptor T (CAR-T) cell therapy. Understanding these evolving strategies is critical for advancing precision immunotherapy in this challenging patient population.

Citations

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  • Over and above what is visible and conventional: development of new territories in colorectal cancer management
    In Ja Park
    Annals of Coloproctology.2026; 42(1): 1.     CrossRef
Rapid Communication
Healthcare reform: let science, not politics, lead the way
Nayoung Kim, Ji Eun Park, Hyun Jung Koo, Sarah Chay, Soo-Youn Ham, So Yeon Kim, Ji-Young Sul, Soon Won Hong, Hyun Wook Baik
Ann Coloproctol. 2024;40(Suppl 1):S48-S49.   Published online May 8, 2024
DOI: https://doi.org/10.3393/ac.2024.00283.0040
  • 3,348 View
  • 103 Download
  • 1 Web of Science
  • 1 Citations
PDF

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  • Health system disruption and oncologic consequences: a retrospective observational study of South Korea’s 2024 medical walkout
    Seung Ho Song, Chang Hyun Kim, Soo Yeun Park
    Journal of Yeungnam Medical Science.2025; 43: 4.     CrossRef
Original Articles
Sensitivity of Various Evaluating Modalities for Predicting a Pathologic Complete Response After Preoperative Chemoradiation Therapy for Locally Advanced Rectal Cancer
Sungwoo Jung, Anuj Parajuli, Chang Sik Yu, Seong Ho Park, Jong Seok Lee, Ah Young Kim, Jong Lyul Lee, Chan Wook Kim, Yong Sik Yoon, In Ja Park, Seok-Byung Lim, Jin Cheon Kim
Ann Coloproctol. 2019;35(5):275-281.   Published online October 31, 2019
DOI: https://doi.org/10.3393/ac.2019.01.07
  • 6,673 View
  • 88 Download
  • 5 Web of Science
  • 6 Citations
AbstractAbstract PDF
Purpose
We investigated the sensitivity of various evaluating modalities in predicting a pathologic complete response (pCR) after preoperative chemoradiation therapy (PCRT) for locally advanced rectal cancer (LARC).
Methods
From a population of 2,247 LARC patients who underwent PCRT followed by surgery at Asan Medical Center, Seoul, Korea from January 2007 to June 2016, we retrospectively analyzed 313 patients (14.1%) who showed a pCR after surgery. Transrectal ultrasound (TRUS), high-resolution magnetic resonance imaging (MRI), abdominopelvic computed tomography (AP-CT), and endoscopy were performed within 2 weeks prior to surgery.
Results
Of the 313 patients analyzed, 256 (81.8%) had a pCR after radical surgery and 57 (18.2%) showed total regression after local excision. Preoperative TRUS, MRI, and AP-CT were performed in 283, 305, and 139 patients, respectively. Among these 3 groups, a prediction of a pCR of the primary tumor was made in 41 (14.5%), 51 (16.7%), and 27 patients (19.4%), respectively, before surgery. A prediction of a clinical N0 stage was made in 204 patients (88.3%) using TRUS, 130 (52.2%) using MRI, and 78 (65.5%) using AP-CT. Of the 211 patients who underwent endoscopy, 87 (41.2%) had a mention of clinical CR in their records. A prediction of a pathologic CR was made for 124 patients (39.6%) through at least one diagnostic modality.
Conclusion
The various evaluation methods for predicting a pCR after PCRT show a predictive sensitivity of 0.15–0.41 for primary tumors and 0.52–0.88 for lymph nodes. Endoscopy is a relatively superior modality for predicting the pCR of the primary tumor of LARC patients.

Citations

Citations to this article as recorded by  
  • Predicting the effectiveness of neoadjuvant therapy in rectal cancer patients: Model construction based on radiomics and carcinoembryonic antigens
    Biyao Liu, Jinyue Feng, Yiguang Hu, Ruisi Tang, Yutong Zhang, Yidian Wang, Yong Wang, Liya Wang, Hang Qiu, Xiaodong Wang
    Intelligent Oncology.2026; 2(1): 100035.     CrossRef
  • Improving prediction of ypT0–1N0 response in rectal cancer: the added value of gross tumor type to magnetic resonance tumor regression grade after chemoradiotherapy in a retrospective cohort study
    Kyong-Min Kang, Mi-Jeong Choi, Hong-min Ahn, Heung-Kwon Oh, Duck-Woo Kim, Jungheum Cho, Won Chang, Young Hoon Kim, Kyoung Ho Lee, Yu Kyung Jun, Yonghoon Choi, Sung-Bum Kang
    Annals of Surgical Treatment and Research.2026; 110(4): 237.     CrossRef
  • Pathologic complete response in rectal cancer: advocating for local excision
    Daniel Gonzalez-Nunez, Luis Torres, Mauricio Gonzalez-Dorado, Juan C. Reyes
    Annals of Coloproctology.2025; 41(6): 592.     CrossRef
  • Comparison between Local Excision and Radical Resection for the Treatment of Rectal Cancer in ypT0-1 Patients: An Analysis of the Clinicopathological Factors and Survival Rates
    Soo Young Oh, In Ja Park, Young IL Kim, Jong-Lyul Lee, Chan Wook Kim, Yong Sik Yoon, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
    Cancers.2021; 13(19): 4823.     CrossRef
  • Predicting Neoadjuvant Chemoradiotherapy Response in Locally Advanced Rectal Cancer Using Tumor-Infiltrating Lymphocytes Density
    Yao Xu, Xiaoying Lou, Yanting Liang, Shenyan Zhang, Shangqing Yang, Qicong Chen, Zeyan Xu, Minning Zhao, Zhenhui Li, Ke Zhao, Zaiyi Liu
    Journal of Inflammation Research.2021; Volume 14: 5891.     CrossRef
  • A Nine-Gene Signature for Predicting the Response to Preoperative Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer
    In Ja Park, Yun Suk Yu, Bilal Mustafa, Jin Young Park, Yong Bae Seo, Gun-Do Kim, Jinpyo Kim, Chang Min Kim, Hyun Deok Noh, Seung-Mo Hong, Yeon Wook Kim, Mi-Ju Kim, Adnan Ahmad Ansari, Luigi Buonaguro, Sung-Min Ahn, Chang-Sik Yu
    Cancers.2020; 12(4): 800.     CrossRef
Effectiveness of Autologous Fat Graft in Treating Fecal Incontinence
Hyeonseok Jeong, Sung Hwan Hwang, Hyoung Rae Kim, Kil O Ryu, Jiyong Lim, Hye Mi Yu, Jihoon Yoon, Chee Young Kim, Kwang-Yong Jeong, Young Jae Jung, In Seob Jeong, Young Gil Choi
Ann Coloproctol. 2019;35(3):144-151.   Published online June 30, 2019
DOI: https://doi.org/10.3393/ac.2018.09.15
  • 8,455 View
  • 106 Download
  • 5 Web of Science
  • 6 Citations
AbstractAbstract PDF
Purpose
The most common risk factor for fecal incontinence (FI) is obstetric injury. FI affects 1.4%–18% of adults. Most patients are unaware when they are young, when symptoms appear suddenly and worsen with aging. Autologous fat graft is widely used in cosmetic surgical field and may substitute for injectable bulky agents in treating FI. Authors have done fat graft for past several years. This article reports the effectiveness of the fat graft in treating FI and discusses satisfaction with the procedure.
Methods
Fat was harvested from both lateral thighs using 10-mL Luer-loc syringe. Pure fat was extracted from harvests and mixed with fat, oil, and tumescent through refinement. Fats were injected into upper border of posterior ano-rectal ring, submucosa of anal canal and intersphincteric space. Thirty-five patients with FI were treated with this method from July 2016 to February 2017 in Busan Hangun Hospital. They were 13 male (mean age, 60.8 years) and 22 female patients (mean age, 63.3 years). The Wexner score was checked before procedure. We evaluated outcome in outpatients by asking the patients. For 19 patients we checked the Wexner score after procedure.
Results
Symptom improved in 29 (82.9%), and not improved in 6 (17.1%). In 2 of 6 patients, they felt better than before procedure, although not satisfied. No improvement in 4. Mean Wexner score was 9.7 before procedure. There were no serious complications such as inflammation or fat embolism.
Conclusion
Autologous fat graft can be an effective alternative treatment for FI. It is safe and easy to perform, and cost effective.

Citations

Citations to this article as recorded by  
  • Regenerative Approach With Autologous Fat Grafting and Stem Cells for the Treatment of Post‐Traumatic Anal Incontinence: A Case Report
    Alexandre da Silva Nishimura, Giuliana Donoso Andrade Silva, Vitor Holmo Figueira, Eduardo Isaac Nishimoto, Pedro Luiz Nishimura Menardi, Igor Rincon Gonçalves Passaglia, Sabrina Thalita dos Reis
    Clinical Case Reports.2026;[Epub]     CrossRef
  • Cell-assisted lipotransfer in treating uncontrollable sepsis associated perianal fistula: a pilot study
    In Seob Jeong, Sung Hwan Hwang, Hye Mi Yu, Hyeonseok Jeong
    Annals of Coloproctology.2024; 40(2): 169.     CrossRef
  • Efficacy of injection of autologous adipose tissue in the treatment of patients with complex and recurrent fistula-in-ano of cryptoglandular origin
    S. Guillaumes, N. J. Hidalgo, I. Bachero, R. Pena, S. T. Nogueira, J. Ardid, M. Pera
    Techniques in Coloproctology.2024;[Epub]     CrossRef
  • Role of Autologous Fat Grafting in the Conservative Treatment of Fecal Incontinence in Children
    Valentina Pinto, Marco Pignatti, Giovanni Parente, Neil Di Salvo, Luca Contu, Mario Lima
    Journal of Clinical Medicine.2023; 12(4): 1258.     CrossRef
  • Clinical and physiological efficacy of the application of autologous fat with platelet rich plasma in treating faecal incontinence
    Elvis Vargas Castillo, Ingrid Melo Amaral, Arisel Domínguez, Sthephfania López, Daniel Chiantera, Mariangela Pérez Paz, Jenils Daniela Coacuto, Andrés Eloy Soto
    Journal of Coloproctology.2020; 40(03): 227.     CrossRef
  • Preliminary Study on the Echo-Assisted Intersphincteric Autologous Microfragmented Adipose Tissue Injection to Control Fecal Incontinence in Children Operated for Anorectal Malformations
    Giovanni Parente, Valentina Pinto, Neil Di Salvo, Simone D’Antonio, Michele Libri, Tommaso Gargano, Vincenzo Davide Catania, Giovanni Ruggeri, Mario Lima
    Children.2020; 7(10): 181.     CrossRef
Does the Different Locations of Colon Cancer Affect the Oncologic Outcome? A Propensity-Score Matched Analysis
Kwan Mo Yang, In Ja Park, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seok-Byung Lim, Na Young Kim, Shinae Hong, Chang Sik Yu, Jin Cheon Kim
Ann Coloproctol. 2019;35(1):15-23.   Published online February 28, 2019
DOI: https://doi.org/10.3393/ac.2018.07.25
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  • 4 Web of Science
  • 3 Citations
AbstractAbstract PDF
Purpose
We evaluate the prognostic value of primary tumor location for oncologic outcomes in patients with colon cancer (CC).
Methods
CC patients treated with curative surgery between 2009 and 2012 were classified into 2 groups: right-sided colon cancer (RCC) and left-sided colon cancer (LCC). Recurrence-free survival (RFS) and overall survival (OS) were examined based on tumor stage. Propensity scores were created using eight variables (age, sex, T stage, N stage, histologic grade, presence of lymphovascular invasion/perineural invasion, and microsatellite instability status).
Results
Overall, 2,329 patients were identified. The 5-year RFSs for RCC and LCC patients were 89.7% and 88.4% (P = 0.328), respectively, and their 5-year OSs were 90.9% and 93.4% (P = 0.062). Multivariate survival analyses were carried out by using the Cox regression proportional hazard model. In the unadjusted analysis, a marginal increase in overall mortality was seen in RCC patients (hazard ratio [HR], 1.297; 95% confidence interval [CI], 0.987–1.704, P = 0.062); however, after multivariable adjustment, similar OSs were observed in those patients (HR, 1.219; 95% CI, 0.91–1.633; P = 0.183). After propensity-score matching with a total of 1,560 patients, no significant difference was identified (P = 0.183). A slightly worse OS was seen for stage III RCC patients (HR, 1.561; 95% CI, 0.967–2.522; P = 0.068) than for stage III LCC patients. The 5-year OSs for patients with stage III RCC and stage III LCC were 85.5% and 90.5%, respectively (P = 0.133).
Conclusion
Although the results are inconclusive, tumor location tended to be associated with OS in CC patients with lymph node metastasis, but it was not related to oncologic outcome.

Citations

Citations to this article as recorded by  
  • Prognostic value of primary tumor location in colorectal cancer: an updated meta-analysis
    Hanieh Gholamalizadeh, Nima Zafari, Mahla Velayati, Hamid Fiuji, Mina Maftooh, Elnaz Ghorbani, Seyed Mahdi Hassanian, Majid Khazaei, Gordon A. Ferns, Elham Nazari, Amir Avan
    Clinical and Experimental Medicine.2023; 23(8): 4369.     CrossRef
  • Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation
    Kristian-Christos Ngamsri, Christoph Jans, Rizki A. Putri, Katharina Schindler, Jutta Gamper-Tsigaras, Claudia Eggstein, David Köhler, Franziska M. Konrad
    Frontiers in Immunology.2020;[Epub]     CrossRef
  • Left colon as a novel high-risk factor for postoperative recurrence of stage II colon cancer
    Liming Wang, Yasumitsu Hirano, Toshimasa Ishii, Hiroka Kondo, Kiyoka Hara, Nao Obara, Shigeki Yamaguchi
    World Journal of Surgical Oncology.2020;[Epub]     CrossRef
Efficacy and Safety of Laparoscopic Hartmann Colostomy Reversal
Won Park, Won Cheol Park, Keun Young Kim, Seok Youn Lee
Ann Coloproctol. 2018;34(6):306-311.   Published online December 20, 2018
DOI: https://doi.org/10.3393/ac.2018.09.07
  • 10,657 View
  • 170 Download
  • 15 Web of Science
  • 14 Citations
AbstractAbstract PDF
Purpose
Hartmann operation is widely recognized as a useful procedure, especially in emergencies involving the rectosigmoid colon. One of the surgeon’s foremost concerns after Hartmann operation is future colostomy reversal, as colostomy reversal after a Hartmann procedure is associated with relatively high morbidity and mortality. Laparoscopic surgical techniques continue to prove useful for an ever-increasing variety of indications. We analyzed the outcomes of laparoscopic Hartmann colostomy reversals at our center.
Methods
We retrospectively analyzed the hospital records of 170 patients who had undergone Hartmann operation between January 2010 and June 2017 at Wonkwang University Hospital. Among 68 Hartmann colostomy reversals, we evaluated and compared the outcomes of 3 groups of patients: 29 patients in the open colostomy reversal group (OG) who had undergone laparotomies for Hartmann reversals, 19 patients in the conversion group (CG) whose laparoscopic procedures had required conversion to a laparotomy, and 20 patients in the laparoscopy group (LG).
Results
The overall reversal rate for Hartmann colostomies was 40.5% during this time period. The duration of hospital stay was significantly shorter among LG patients (10.15 ± 2.94 days) than among OG patients (16 ± 9.5 days). The overall complication rate among OG patients was higher than that among LG patients (adjusted odds ratio, 8.78; P = 0.01). The most common complication was postoperative ileus (19.1%).
Conclusion
If no contraindications to laparoscopy exist, surgeons should favor a laparoscopic reversal of Hartmann operation over an open reversal.

Citations

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  • Complete prevention of anastomotic leakage using total enteric flow diversion
    Tao Hu, Jing Wang, Nan-Hui Yu
    World Journal of Gastrointestinal Surgery.2025;[Epub]     CrossRef
  • Surgical Outcomes of Open and Laparoscopic Hartmann Reversal: A Single-Center Comparative Study
    Mu-Han Tsai, Ming-Jenn Chen, Khaa-Hoo Ong, Chih-Ying Lu, Chung-Han Ho, Hsuan-Yi Huang, Yu-Feng Tian, I-Ning Yang
    Cureus.2024;[Epub]     CrossRef
  • Laparoscopic versus open Hartmann reversal: a propensity score matching analysis
    Li Tan, Xiao-Yu Liu, Bin Zhang, Lian-Lian Wang, Zheng-Qiang Wei, Dong Peng
    International Journal of Colorectal Disease.2023;[Epub]     CrossRef
  • Comparison of outcomes between laparoscopic and open Hartmann's reversal: A single‐center retrospective study in Japan
    Aya Sato, Ken Imaizumi, Hiroyuki Kasajima, Keisuke Obuchi, Kentaro Sato, Daisuke Yamana, Yosuke Tsuruga, Minoru Umehara, Michihiro Kurushima, Kazuaki Nakanishi
    Asian Journal of Endoscopic Surgery.2022; 15(1): 137.     CrossRef
  • A Case of Laparoscopic Hartmann's Procedure Followed by Laparoscopic Reversal for Perforated Diverticulitis
    Ryo Maemoto, Shingo Tsujinaka, Ryotaro Sakio, Nao Kakizawa, Rei Takahashi, Yuuri Hatsuzawa, Yasuaki Kimura, Erika Machida, Sawako Tamaki, Hideki Ishikawa, Yasuyuki Miyakura, Toshiki Rikiyama
    Nippon Daicho Komonbyo Gakkai Zasshi.2022; 75(1): 36.     CrossRef
  • Is laparoscopy a reliable alternative to laparotomy in Hartmann's reversal? An updated meta-analysis
    D. Chavrier, A. Alves, B. Menahem
    Techniques in Coloproctology.2022; 26(4): 239.     CrossRef
  • Laparoscopic Hartmann's reversal has better clinical outcomes compared to open surgery: An international multicenter cohort study involving 502 patients
    Anwar Medellin Abueta, Nairo Javier Senejoa, Mauricio Pedraza Ciro, Lina Fory, Carlos Perez Rivera, Carlos Edmundo Martinez Jaramillo, Lina Maria Mateus Barbosa, Heinz Orlando Ibañez Varela, Javier A. Carrera, Rafael Garcia Duperly, Luis A Sanchez, Ivan D
    Health Science Reports.2022;[Epub]     CrossRef
  • Laparoscopic Hartmann reversal: experiences from a developing country
    Dung Anh Nguyen, Tuong-Anh Mai-Phan, Truc Thanh Thai, Hai Van Nguyen
    Annals of Coloproctology.2022; 38(4): 297.     CrossRef
  • Open versus laparoscopic Hartmann’s procedure: a systematic review and meta-analysis
    Yingjia Zhang, Chunxi Liu, Kameswara Rishi Yeshayahu Nistala, Choon Seng Chong
    International Journal of Colorectal Disease.2022; 37(12): 2421.     CrossRef
  • Laparoscopic Versus Open Hartmann Reversal: A Case-Control Study
    Paolo Panaccio, Tommaso Grottola, Rossana Percario, Federico Selvaggi, Severino Cericola, Alfonso Lapergola, Maira Farrukh, Giuseppe Di Martino, Marco Ricciardiello, Pierluigi Di Sebastiano, Fabio Francesco Di Mola, Todd Pesavento
    Surgery Research and Practice.2021; 2021: 1.     CrossRef
  • Effects of Laparoscopic Hartmann Reversal on Short-term Operative Outcomes Among Vietnamese Patients
    Viet Van Ung, Bang Cong Huynh, Vinh Chi Le, Dang Ngoc Tran, Trung Nguyen Vo, Tan Van Pham, Bac Hoang Nguyen
    Journal of Coloproctology.2021; 41(02): 117.     CrossRef
  • A comparative study between open versus laparoscopic Hartmann reversal
    Hye Jung Cho, Woo Ram Kim, Jong Woo Kim
    Medicine.2021; 100(47): e27976.     CrossRef
  • Colorectal reconstructions following Hartmann’s procedure: challenges and solutions
    A. N. Igolkin, V. V. Polovinkin
    Innovative medicine of Kuban.2020; (4): 51.     CrossRef
  • Emergency Hartmann’s Procedure and its Reversal: A Totally Laparoscopic 2-Step Surgery for the Treatment of Hinchey III and IV Diverticulitis
    Diletta Cassini, Michelangelo Miccini, Farshad Manoochehri, Matteo Gregori, Gianandrea Baldazzi
    Surgical Innovation.2019; 26(6): 770.     CrossRef
Efficacy of Dose-Escalated Radiotherapy for Recurrent Colorectal Cancer
Sunmi Jo, Yunseon Choi, Sung-Kwang Park, Jin-Young Kim, Hyun Jung Kim, Yun-Han Lee, Won Yong Oh, Heunglae Cho, Ki Jung Ahn
Ann Coloproctol. 2016;32(2):66-72.   Published online April 30, 2016
DOI: https://doi.org/10.3393/ac.2016.32.2.66
  • 5,878 View
  • 36 Download
  • 8 Web of Science
  • 7 Citations
AbstractAbstract PDF
Purpose

This study aimed to evaluate the effects of radiotherapy (RT) on progression-free survival (PFS) for patients with recurrent colorectal cancer.

Methods

We reviewed the records of 22 patients with recurrent colorectal cancer treated with RT between 2008 and 2014. The median radiation dose for recurrent disease was 57.6 Gy (range, 45–75.6 Gy). Patients were divided into 2 groups according to the type of RT: patients underwent RT without previous history of irradiation (n = 14) and those treated with secondary RT (reirradiation: n = 8) at the time of recurrence.

Results

The median follow-up period was 24.9 months (range, 4.5–66.6 months). Progression was observed in 14 patients (including 8 with loco-regional failure and 9 with distant metastases). Distant metastases were related to the RT dose (<70 Gy, P = 0.031). The 2-year loco-regional control (LRC), PFS, and overall survival (OS) rates were 74.6%, 45.1%, and 82.0%, respectively. The LRC rate was not different between the patients treated with RT for the first time and those treated with reirradiation (P = 0.101, 2-year LRC 79.5% vs. 41.7%). However, reirradiation was related to poor PFS (P = 0.022) and OS (P = 0.002). An escalated RT dose (≥70 Gy) was associated with a higher PFS (P = 0.014, 2-year PFS 63.5% vs. 20.8%).

Conclusion

Salvage RT for locally recurrent colorectal cancer can be offered when surgery is impossible. Dose-escalated RT shows a possible benefit in reducing the risk of progression.

Citations

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  • Carbon-ion Radiotherapy for Colorectal Cancer
    Shigeru Yamada, Hirotoshi Takiyama, Yuka Isozaki, Makoto Shinoto, Hirokazu Makishima, Naoyoshi Yamamoto, Hiroshi Tsuji
    Journal of the Anus, Rectum and Colon.2021; 5(2): 113.     CrossRef
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    Zhenkui Zuo, Shuling Ji, Lulu He, Yage Zhang, Zining Peng, Jiarui Han
    Cell Biology International.2020; 44(11): 2284.     CrossRef
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    Shing Yau Tam, Vincent W. C. Wu
    Frontiers in Oncology.2019;[Epub]     CrossRef
  • Comparison of overall survival and quality of life between patients undergoing anal reconstruction and patients undergoing traditional lower abdominal stoma after radical resection
    P. Du, S.-Y. Wang, P.-F. Zheng, J. Mao, H. Hu, Z.-B. Cheng
    Clinical and Translational Oncology.2019; 21(10): 1390.     CrossRef
  • Prospective Observational Study of High-Dose Carbon-Ion Radiotherapy for Pelvic Recurrence of Rectal Cancer (GUNMA 0801)
    Shintaro Shiba, Masahiko Okamoto, Hiroki Kiyohara, Tatsuya Ohno, Takuya Kaminuma, Takayuki Asao, Hitoshi Ojima, Ken Shirabe, Hiroyuki Kuwano, Takashi Nakano
    Frontiers in Oncology.2019;[Epub]     CrossRef
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    Fang Ju, Na Li, Wenming Wang, Haicheng Yuan
    Molecular Medicine Reports.2019;[Epub]     CrossRef
  • Dose-Escalated Radiotherapy for the Treatment of Patients With Recurrent Colorectal Cancer
    Hyung Jin Kim, Seong Taek Oh
    Annals of Coloproctology.2016; 32(2): 47.     CrossRef
Distribution and Impact of the Visceral Fat Area in Patients With Colorectal Cancer
Hyeon Yu, Yong-Geul Joh, Gyung-Mo Son, Hyun-Sung Kim, Hong-Jae Jo, Hae-Young Kim
Ann Coloproctol. 2016;32(1):20-26.   Published online February 29, 2016
DOI: https://doi.org/10.3393/ac.2016.32.1.20
  • 8,223 View
  • 65 Download
  • 22 Web of Science
  • 23 Citations
AbstractAbstract PDF
Purpose

The purposes of this study were to investigate the distribution of the visceral fat area (VFA) and general obesity and to compare visceral and general obesity as predictors of surgical outcomes of a colorectal cancer resection.

Methods

The prospectively collected data of 102 patients with preoperatively-diagnosed sigmoid colon or rectal cancer who had undergone a curative resection at Pusan National University Yangsan Hospital between April 2011 and September 2012 were reviewed retrospectively. Men with a VFA of >130 cm2 and women with a VFA of >90 cm2 were classified as obese (VFA-O, n = 22), and the remaining patients were classified as nonobese (VFA-NO, n = 80).

Results

No differences in morbidity, mortality, postoperative bowel recovery, and readmission rate after surgery were observed between the 2 groups. However, a significantly higher number of harvested lymph nodes was observed in the VFA-NO group compared with the VFA-O group (19.0 ± 1.0 vs. 13.5 ± 1.2, respectively, P = 0.001).

Conclusion

Visceral obesity has no influence on intraoperative difficulties, postoperative complications, and postoperative recovery in patients with sigmoid colon or rectal cancer.

Citations

Citations to this article as recorded by  
  • Preoperative body composition metrics as predictors for outcomes in colorectal cancer surgeries
    Dorsa Salabat, Asma Mousavi, Shayan Shojaei, Razman Arabzadeh Bahri, Hanieh Radkhah
    Annals of Medicine & Surgery.2025; 87(4): 2243.     CrossRef
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    Yulong Wang, Xijuan Liu, Xiao Feng, Xing Jiang, Lili Huang
    Frontiers in Oncology.2025;[Epub]     CrossRef
  • Modified predictive model incorporating the waist-to-hip ratio for advanced colorectal neoplasia: A step toward precision screening
    Zong-Xian Zhao, Zong-Ju Hu
    World Journal of Clinical Oncology.2025;[Epub]     CrossRef
  • Influence of anthropometric factors on estimating intraoperative challenges in bariatric surgery: a prospective correlational study
    Justyna Rymarowicz, Izabela Karpińska, Izabela Powalacz, Magdalena Pyzik, Bartosz Iwanowski, Jakub Pośpiech, Piotr Panek, Piotr Major
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    桂芳 崔
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Case Reports
Necrotizing Fasciitis Arising From an Enterocutaneous Fistula in a Case of an Appendiceal Mucocele
Keun Young Kim, Won Cheol Park
Ann Coloproctol. 2015;31(6):246-250.   Published online December 31, 2015
DOI: https://doi.org/10.3393/ac.2015.31.6.246
  • 5,237 View
  • 41 Download
  • 2 Web of Science
  • 2 Citations
AbstractAbstract PDF

An appendiceal mucocele (AM) is a rare tumorous condition of the appendix. Many patients with AM are admitted to the hospital with abdominal pain or discomfort, and many cases are found incidentally. Although the rate of complications in patients with AM is very low, if left untreated, a mucocele may rupture and produce a potentially fatal entity known as pseudomyxoma peritonei. In this paper, we report a case of an 80-year-old man with necrotizing fasciitis arising from an enterocutaneous fistula caused by AM.

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  • Enterocutaneous fistula resulting from the drainage of a contained appendiceal perforation secondary to a partially obstructing low-grade appendiceal mucinous neoplasm
    Ryan Cohen, Katie McKean, Stephanie Chetrit
    BMJ Case Reports.2021; 14(8): e244546.     CrossRef
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    Oliver Beaumont, Robert Miller, Richard Guy
    BMJ Case Reports.2016; 2016: bcr2016217293.     CrossRef
Metastatic Spermatic Cord Tumor From Colorectal Cancer
Ji Geon Jang, Hye Yun Jeong, Ki Soo Kim, Mi Jung Park, Jin Sook Lee, Sang Su Kim, Ho Young Kim
Ann Coloproctol. 2015;31(5):202-204.   Published online October 31, 2015
DOI: https://doi.org/10.3393/ac.2015.31.5.202
  • 5,624 View
  • 40 Download
  • 3 Web of Science
  • 2 Citations
AbstractAbstract PDF

Metastatic tumors of the spermatic cord are extremely rare, and the prognosis for patients is typically poor. In the majority of cases, the primary tumor occurs in the gastrointestinal tract. We report a case of a 62-year-old man with a metastatic spermatic cord tumor. The patient complained of groin discomfort with a tender mass in the right inguinal area. An excisional biopsy was performed, and the pathologic finding was a metastatic mucinous adenocarcinoma. We performed a systemic evaluation including colonoscopy, abdominal computed tomography, and total-body positron emission tomography, and the primary tumor was confirmed to involve the total colon, including the cecum, sigmoid colon, and rectum. The pathologic finding for rectum revealed a mucinous adenocarcinoma compatible with a metastatic spermatic cord tumor.

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  • Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literature
    Pranjal Rai, Pradeep Kumar, Joe Joseph, Dhairya A. Lakhani
    Radiology Case Reports.2025; 20(8): 4004.     CrossRef
  • Paratesticular metastasis from colorectal adenocarcinoma presenting as hydrocele: a rare case report and literature review
    XiaoJun Huang, KeLi Xu, Yin Zhao, MinHui Chen, ZheYang Li
    Frontiers in Oncology.2024;[Epub]     CrossRef
Original Article
ERCC1 as a Predictive Marker for FOLFOX Chemotherapy in an Adjuvant Setting
Chee Young Kim, Sang Hyuk Seo, Min Sung An, Kwang Hee Kim, Ki Beom Bae, Jin Won Hwang, Ji Hyun Kim, Bo Mi Kim, Mi Seon Kang, Min Kyung Oh, Kwan Hee Hong
Ann Coloproctol. 2015;31(3):92-97.   Published online June 30, 2015
DOI: https://doi.org/10.3393/ac.2015.31.3.92
  • 5,695 View
  • 43 Download
  • 7 Web of Science
  • 6 Citations
AbstractAbstract PDF
Purpose

The purpose of this study was to identify the excision repair cross-complementation group 1 (ERCC1) as a predictive marker for FOLFOX adjuvant chemotherapy in stages II and III colon cancer patients.

Methods

A total of 166 high risk stages II and III colon cancer patients were retrospectively enrolled in this study, and data were collected prospectively. They underwent a curative resection followed by FOLFOX4 adjuvant chemotherapy. We analyzed ERCC1 expression in the primary colon tumor by using immunohistochemical staining. The oncological outcomes included the 5-year disease-free survival (DFS) rate. The DFS was analyzed by using the Kaplan-Meier method with the log-rank test. A Cox proportional hazard model was used for the prognostic analysis.

Results

ERCC1-positive expression was statistically significant in the older patients (P = 0.032). In the multivariate analysis, the prognostic factors for DFS were female sex (P = 0.016), N stage (P = 0.009), and postoperative carcinoembryonic antigen level (P = 0.001), but ERCC1 expression was not a statistically significant prognostic factor for DFS in the univariate analysis (P = 0.397). The 5-year DFS rate was not significantly associated with the ERCC1 expression in all patients (P = 0.396) or with stage III disease (P = 0.582).

Conclusion

We found that ERCC1 expression was not significantly correlated with the 5-year DFS as reflected by the oncologic outcomes in patients with high-risk stages II and III colon cancer treated with FOLFOX adjuvant chemotherapy.

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  • ERCC1 and MGMT Methylation as a Predictive Marker of Relapse and FOLFOX Response in Colorectal Cancer Patients from South Tunisia
    Dhouha Jamai, Raja Gargouri, Boulbaba Selmi, Abdelmajid Khabir
    Genes.2023; 14(7): 1467.     CrossRef
  • EXPRESSION OF NUCLEOTIDE EXCISION REPAIR PROTEIN ERCC1 IN TUMOR TISSUE AS A PROGNOSTIC FACTOR IN COLORECTAL CANCER
    Irina Aleksandrovna Bogomolova, Dinara Rishatovna Dolgova, Inna Ivanovna Antoneeva, Ekaterina Gennad'evna Parmenova, Il'seya Rinatovna Myagdieva, Mark Alekseevich Urevskiy
    Ulyanovsk Medico-biological Journal.2023; (3): 167.     CrossRef
  • ERCC1, PARP-1, and AQP1 as predictive biomarkers in colon cancer patients receiving adjuvant chemotherapy
    Aziza E. Abdelrahman, Doaa Abdelaziz Ibrahim, Ahmed El-Azony, Ahmed A. Alnagar, Amr Ibrahim
    Cancer Biomarkers.2020; 27(2): 251.     CrossRef
  • Using patient-derived xenograft models of colorectal liver metastases to predict chemosensitivity
    Kai M. Brown, Aiqun Xue, Sohel M. Julovi, Anthony J. Gill, Nick Pavlakis, Jaswinder S. Samra, Ross C. Smith, Thomas J. Hugh
    Journal of Surgical Research.2018; 227: 158.     CrossRef
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    Daniela Rodrigues, Adhemar Longatto-Filho, Sandra F. Martins
    BioMed Research International.2016; 2016: 1.     CrossRef
  • ERCC1 and the Prognosis for Patients With Colon Cancer Receiving Oxaliplatin-Based Adjuvant Chemotherapy
    Moo-Jun Baek
    Annals of Coloproctology.2015; 31(3): 81.     CrossRef
Case Reports
Acute Peritonitis Caused by a Fibrosarcoma of the Transverse Colon in an Adult
Seok Youn Lee, Jung Nam Kwon, Keun Young Kim
Ann Coloproctol. 2014;30(6):280-284.   Published online December 31, 2014
DOI: https://doi.org/10.3393/ac.2014.30.6.280
  • 4,984 View
  • 37 Download
  • 1 Web of Science
  • 1 Citations
AbstractAbstract PDF

A fibrosarcoma is a malignant mesenchymal tumor derived from fibrous connective tissue. It usually develops in the deep soft tissues of the extremities, as well as the trunk, head, and neck. In extremely rare cases, a fibrosarcoma may occur in the gastrointestinal tract. Most cases of fibrosarcoma in the gastrointestinal tract have been observed in the pediatric age group while only a few cases have been reported in adults. A 61-year-old male presented with pain in the entire abdominal region. Chest radiography showed free air in the subphrenic space. After an emergency operation, we found a solid mass around the transverse colon and performed a segmental resection with a lymphatic dissection of the transverse colon, including the mass. A pathologic examination showed a fibrosarcoma with a perforation. There was no perioperative complication. The patient was discharged on postoperative day 11 and had follow-ups for 1 year without any recurrence.

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  • Case Report: Bowel obstruction caused by an adult fibrosarcoma located in the pelvis
    Sixian Wang, Yiming Liu, Jixin Zhang, Junling Zhang, Xin Wang
    Frontiers in Surgery.2025;[Epub]     CrossRef
Regression of Colonic Adenomas After Treatment With Sulindac in Familial Adenomatous Polyposis: A Case With a 2-Year Follow-up Without a Prophylactic Colectomy
Kyu Young Kim, Seong Woo Jeon, Jung Gil Park, Chung Hoon Yu, Se Young Jang, Jae Kwang Lee, Hee Young Hwang
Ann Coloproctol. 2014;30(4):201-204.   Published online August 26, 2014
DOI: https://doi.org/10.3393/ac.2014.30.4.201
  • 7,542 View
  • 38 Download
  • 9 Web of Science
  • 9 Citations
AbstractAbstract PDF

Familial adenomatous polyposis (FAP) is an autosomal dominant disorder characterized by hundreds of colorectal adenomatous polyps that progress to colorectal cancer. Management of patients with FAP is with a total colectomy. Chemopreventive strategies have been studied in FAP patients in an effort to delay the development of adenomas in the upper and the lower gastrointestinal tract and to prevent recurrence of adenomas in the retained rectum of patients after prophylactic surgery. Sulindac, a nonsteroidal anti-inflammatory drug, causes regression of colorectal adenomas in the retained rectal segment of FAP patients. However, evidence regarding long-term use of this therapy and its effect on the intact colon has been insufficient. We report a case in which the long-term use of sulindac was effective in reducing the size and the number of colonic polyps in patients with FAP without a prophylactic colectomy and polypectomy; we also present a review of the literature.

Citations

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  • Emerging Strategies for Drug-Based Cancer Risk Reduction
    Maria Daca-Álvarez, Angelo Brunori, Alessio Carbone, Chantelle Carbonell, Catherine M. Tangen, Joseph M. Unger, M. Scott Lucia, Martino Oliva, Andrea De Censi, Darren R. Brenner, Ian M. Thompson, Francesc Balaguer
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    Maria Daca-Álvarez, Andrew Latchford, Maria Pellisé, Francesc Balaguer
    Familial Cancer.2025;[Epub]     CrossRef
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    Zhipin Liang, Ruixia Ma, Bin Yi, Adam I. Riker, Yaguang Xi
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    Allie E. Steinberger, Maggie L. Westfal, Paul E. Wise
    Clinics in Colon and Rectal Surgery.2024; 37(03): 191.     CrossRef
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    Eugénie Chevalier, Robert Benamouzig
    Therapeutic Advances in Gastroenterology.2023;[Epub]     CrossRef
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    Khalid Asadi, Lynnette R. Ferguson, Martin Philpott, Nishi Karunasinghe
    Journal of Cancer Prevention.2017; 22(3): 135.     CrossRef
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    Young-Min Han, Jong-Min Park, Ji-Young Cha, Migyeong Jeong, Eun-Jin Go, Ki Baik Hahm
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  • NOSH-sulindac (AVT-18A) is a novel nitric oxide- and hydrogen sulfide-releasing hybrid that is gastrointestinal safe and has potent anti-inflammatory, analgesic, antipyretic, anti-platelet, and anti-cancer properties
    Khosrow Kashfi, Mitali Chattopadhyay, Ravinder Kodela
    Redox Biology.2015; 6: 287.     CrossRef
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    Reactions Weekly.2015; 1570(1): 198.     CrossRef
Surgical Management of Unicentric Castleman's Disease in the Abdomen
Min-Sang Kim, Jae-Kyun Ju, Young Kim
Ann Coloproctol. 2014;30(2):97-100.   Published online April 25, 2014
DOI: https://doi.org/10.3393/ac.2014.30.2.97
  • 5,279 View
  • 30 Download
  • 7 Web of Science
  • 7 Citations
AbstractAbstract PDF

Castleman's disease (CD) is a rare lymphoproliferative disorder that can involve single or multiple lymph nodes in the body. Especially, the localized form of CD is known to be well-controlled by using a surgical resection. On occasion, the surgeon may confront an abdominal and retroperitoneal mass of unknown origin. Thus, we present this case in which we treated a 16-year-old female patient for CD and investigated how to evaluate and manage the situation from the standpoint of CD. Also, we give a review of the pathology, clinical manifestation, diagnosis, and treatment of CD.

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  • Unicentric Castleman disease treated with rituximab before surgery: clinicopathologic findings
    Marco Paulli, Giuseppe Neri, Francesca Antoci, Edoardo D’Este, Marco Minetto, Federico Carpi, Martina La Fauci, Marcello Gambacorta, Marco Lucioni, Luca Arcaini
    Annals of Hematology.2025; 104(10): 5531.     CrossRef
  • Retroperitoneal Castleman’s disease in a young Nepalese girl: A rare cause of childhood abdominal mass
    Ashish Lal Shrestha, Aakash Mishra, Sagar Khadka, Ramesh Dhakhwa
    Annals of Medicine & Surgery.2024; 86(2): 1080.     CrossRef
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    Himanshu Srivastava, DulgantiSantosh Reddy, ShreyasN Shah, Vandana Shah
    Journal of Oral and Maxillofacial Pathology.2020; 24(3): 593.     CrossRef
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    Stavros Tsotsolis, I. A. Ziogas, D. Miliaras, G. Tsoulfas
    Hellenic Journal of Surgery.2019; 91(1): 33.     CrossRef
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    Michael Haap, Julia Wiefels, Marius Horger, Annika Hoyer, Karsten Müssig
    Blood Reviews.2018; 32(3): 225.     CrossRef
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    Flavius Mocian, Sorin Sorlea, Marius Coros
    Journal of Interdisciplinary Medicine.2018; 3(2): 102.     CrossRef
  • Surgical management of isolated retroperitoneal Castleman's disease: A case report
    JUN XU, BO ZHOU, HUA-LI CAO, BO WANG, SHENG YAN, SHU-SEN ZHENG
    Oncology Letters.2016; 11(3): 2123.     CrossRef
Original Article
Effect of Gum Chewing on the Recovery From Laparoscopic Colorectal Cancer Surgery
Duk Yeon Hwang, Ho Young Kim, Ji Hoon Kim, In Gyu Lee, Jun Ki Kim, Seung Taek Oh, Yoon Suk Lee
Ann Coloproctol. 2013;29(6):248-251.   Published online December 31, 2013
DOI: https://doi.org/10.3393/ac.2013.29.6.248
  • 6,220 View
  • 46 Download
  • 7 Citations
AbstractAbstract PDF
Purpose

We aimed to examine the effect of gum chewing after laparoscopic colorectal cancer surgery.

Methods

We reviewed the medical records of patients who underwent laparoscopic colorectal cancer surgery in Incheon St. Mary's Hospital, The Catholic University of Korea School of Medicine. We divided the patients into 2 groups: group A consisted of 67 patients who did not chew gum; group B consisted of 65 patients who chewed gum. We analyzed the short-term clinical outcomes between the two groups to evaluate the effect of gum chewing.

Results

The first passage of gas was slightly earlier in group B, but the difference was not significant. However, the length of hospital stay was 6.7 days in group B, which was significantly shorter than that in group A (7.3 days, P = 0.018).

Conclusion

This study showed that length of postoperative hospital stay was shorter in the gum-chewing group. In future studies, we expect to elucidate the effect of gum chewing on the postoperative recovery more clearly.

Citations

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  • Postoperative Ileus and Nonpharmacological Nursing Interventions for Colorectal Surgery: A Systematic Review
    Hande Nur Arslan, Sevilay Şenol Çelik, Gamze Bozkul
    Journal of PeriAnesthesia Nursing.2025; 40(1): 181.     CrossRef
  • Chewing Gum and Postoperative Nausea and Vomiting: Comment
    Jamie Elmawieh, Alexander Nagrebetsky, Marta Dias Vaz, Anne Rüggeberg, Ib Jammer, Anne Marie Camilleri Podesta, Barbara Hammer, Simone Silvestrini, Ehrenfried Schindler, Federico Bilotta
    Anesthesiology.2025; 143(3): 785.     CrossRef
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    Lanlan Zheng, Xuan Zhang, Baoyu Ma, Yuan Yuan, Hui Yang
    International Journal of Colorectal Disease.2025;[Epub]     CrossRef
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    Nahima Miah, Sanjay Noonan, Emma Copeland, Eastern Road, Elaine Macaninch
    International Journal of Complementary & Alternative Medicine.2021; 14(2): 69.     CrossRef
  • Chewing Gum for Intestinal Function Recovery after Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis
    Binbin Mei, Wenting Wang, Feifei Cui, Zunjia Wen, Meifen Shen
    Gastroenterology Research and Practice.2017; 2017: 1.     CrossRef
  • Chewing gum for postoperative recovery of gastrointestinal function
    Vaneesha Short, Georgia Herbert, Rachel Perry, Charlotte Atkinson, Andrew R Ness, Christopher Penfold, Steven Thomas, Henning Keinke Andersen, Stephen J Lewis
    Cochrane Database of Systematic Reviews.2015;[Epub]     CrossRef
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    Hungdai Kim
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Case Report
Mucosal Schwann-Cell Hamartoma Diagnosed by Using an Endoscopic Snare Polypectomy
Myoung Nam Bae, Jung Eun Lee, Sang Mook Bae, Eun Young Kim, Eun Ok Kim, Sung Hoon Jung, Jung Hwan Oh, Ki Ok Min
Ann Coloproctol. 2013;29(3):130-134.   Published online June 30, 2013
DOI: https://doi.org/10.3393/ac.2013.29.3.130
  • 8,960 View
  • 93 Download
  • 18 Citations
AbstractAbstract PDF

Colorectal polyps of mesenchymal origin are a rare group of colorectal disorders. A "mucosal Schwann-cell hamartoma," which is one type of polypoid lesion that originates from the mesenchyme, is a newly-proposed disease entity to be distinguished from the neurofibromas found in type-1 neurofibromatosis. This lesion is composed of pure Schwann-cell proliferation in the lamina propria and shows diffuse immunoreactivity for the S-100 protein. We report a case of a polypoid lesion of the colon with the features of this recently-proposed disease entity.

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    G. Castillo-López, S. González-Vázquez, T. Iscar-Galán, L. Alarcón-García, J.M. Riesco-López
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    G. Castillo-López, S. González-Vázquez, T. Iscar-Galán, L. Alarcón-García, J.M. Riesco-López
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    Anandita Dalal, Nalini Bansal, Adnan Rafiq, Rajeev Sen
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    Francisco García-Molina, José Antonio Ruíz-Macia, Joaquin Sola
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Original Article
The Use of a Staged Drainage Seton for the Treatment of Anal Fistulae or Fistulous Abscesses
Cheong Ho Lim, Hyeon Keun Shin, Wook Ho Kang, Chan Ho Park, Sa Min Hong, Seung Kyu Jeong, June Young Kim, Hyung Kyu Yang
J Korean Soc Coloproctol. 2012;28(6):309-314.   Published online December 31, 2012
DOI: https://doi.org/10.3393/jksc.2012.28.6.309
  • 9,932 View
  • 69 Download
  • 29 Citations
AbstractAbstract PDF
Purpose

The aim of this retrospective study was to evaluate the rate of recurrence and incontinence after the treatment of fistulae or fistulous abscesses by using the staged drainage seton method.

Methods

According to the condition, a drainage seton alone or a drainage seton combined with internal opening (IO) closure and relocation of the seton was used. After a period of time, the seton was changed with 3-0 nylon; then, after another period of time, the authors terminated the treatment by removing the 3-0 nylon. Telephone interviews were used for follow-up. The following were evaluated: the relationship between the type of fistula and recurrence; the relationship between the type of fistula and the period of treatment; the relationship between the recurrence and presence of abscess; the relationship between IO closure and recurrence; the relationship between the period of seton change and recurrence; reported continence for flatus, liquid stool, and solid stool.

Results

The recurrence rate of fistulae or suppuration was 6.5%, but for cases of horseshoe extension, the recurrence rate was 57.1%. The rate of recurrence was related to the type of fistula (P = 0.001). Incontinence developed in 3.8% of the cases. No statistically significant relationship was found between the rate of recurrence and the presence of an abscess or between the closure of the IO and the period of seton change or removal.

Conclusion

In the treatment of anal fistulae or fistulous abscesses, the use of a staged drainage seton can reduce the rate of recurrence and incontinence.

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Case Report
A Case of Primary Ovarian Lymphoma Presenting as a Rectal Submucosal Tumor
Il Soon Jung, Seul Young Kim, Kyu Seup Kim, Kwang Hun Ko, Jae Kyu Sung, Hyun Young Jeong, Ji Yeoun Kim, Hee Seok Moon
J Korean Soc Coloproctol. 2012;28(2):111-115.   Published online April 30, 2012
DOI: https://doi.org/10.3393/jksc.2012.28.2.111
  • 5,190 View
  • 29 Download
  • 2 Citations
AbstractAbstract PDF

Primary ovarian lymphoma is a rare malignancy whose symptoms or signs are usually nonspecific. In this article, we report a very rare case initially presenting as a rectal submucosal-tumor-like lesion with a defecation disturbance caused by primary ovarian lymphoma with bilateral involvement. A 42-year-old woman visited chungnam national university hospital complaining of persistent defecation disturbance for 6 months. Colonoscopy demonstrated compression of the rectum by an extrinsic mass mimicking a rectal submucosal tumor. Magnetic resonance imaging detected bilateral ovarian tumors, 9.3 cm and 5.4 cm each in diameter, compressing the rectum without enlarged lymph nodes. The diagnosis was established following a bilateral adnexectomy and histological studies of the excised tissue. The tumor was classified as a diffuse large B-cell lymphoma. The patient was prescribed six cycles of standard CHOP (cyclophosphamide, hydroxydaunorubicin, vincristine, prednisolone) regimen and is presently on treatment.

Citations

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    Wei Liu, Houyun Xu, Jibo Hu, Xiping Yu, Junjie Zhou, Hongjie Hu
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Original Article
The Synchronous Prevalence of Colorectal Neoplasms in Patients with Stomach Cancer
Sang Su Lee, Woon Tae Jung, Cha Young Kim, Chang Yoon Ha, Hyun Ju Min, Hyun Jin Kim, Tae Hyo Kim
J Korean Soc Coloproctol. 2011;27(5):246-251.   Published online October 31, 2011
DOI: https://doi.org/10.3393/jksc.2011.27.5.246
  • 6,536 View
  • 32 Download
  • 10 Citations
AbstractAbstract PDF
Purpose

The association between stomach cancer and colorectal cancer is controversial. The purpose of this study was to determine the synchronous prevalence of colorectal neoplasms in patients with stomach cancer.

Methods

A total of 123 patients with stomach cancer (86 male) and 246 consecutive, age- and sex-matched persons without stomach cancer were analyzed from July 2005 to June 2010. All of them underwent colonoscopy within 6 months after undergoing gastroscopy.

Results

The prevalence of colorectal neoplasms was significantly higher in the stomach cancer group (35.8%) than in the control group (17.9%) (P < 0.001). Colorectal neoplasms were more prevalent in the patients with stomach cancer (odds ratio [OR], 3.10; 95% confidence interval [CI], 1.71 to 5.63). In particular, the difference in the prevalence of colorectal neoplasms was more prominent in the patients above 50 years old (OR, 3.54; 95% CI, 1.80 to 6.98).

Conclusion

The results showed that the synchronous prevalence of colorectal neoplasms was higher in patients with stomach cancer than in those without stomach cancer. Therefore, patients with stomach cancer should be regarded as a high-risk group for colorectal neoplasms, and colonoscopy should be recommended for screening.

Citations

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Case Report
Laparoscopic Treatment of Adult Sigmoidorectal Intussusception Caused by a Mucinous Adenocarcinoma of the Sigmoid Colon: A Case Report
Seok Youn Lee, Won Cheol Park, Jeong Kyun Lee, Dong Baek Kang, Young Kim, Ki Jung Yun
J Korean Soc Coloproctol. 2011;27(1):44-49.   Published online February 28, 2011
DOI: https://doi.org/10.3393/jksc.2011.27.1.44
  • 6,600 View
  • 57 Download
  • 3 Citations
AbstractAbstract PDF

Intussusception is a rare cause of intestinal obstruction in adult patients, but is common in children. In fact, it accounts for an estimated 1% of all cases of bowel obstruction in adults, although adult intussusception of the large intestine is rare. Sigmoidorectal intussusception, however, is a rare variety with few cases reported in the literature. A mucinous adenocarcinoma, a subtype of adenocarcinoma, is characterized by extracellular mucin production and accounts for between 5% and 15% of the neoplasms of the colon and rectum. Despite the general consensus supporting surgical resections for adult intussuceptions, controversy remains over whether intussuceptions should be reduced before resection. Most cases of colon intussusception should not be reduced before resection because they most likely represent a primary adenocarcinoma. However, prior reduction followed by a resection can be considered for the sigmoidorectal intussusception to avoid inadvertent low rectal cancer sugery. We experienced one case of sigmoidorectal intussusception caused by a mucinous adenocarcinoma of the sigmoid colon in a 79-year-old woman. Abdominal computed tomography demonstrated a sigmoidorectal intussusception. After the end-to-end anastomosis-dilator-assisted reduction, the patient underwent a laparoscopic oncological anterior resection under the impression that a sigmoidorectal intussusception existed. We report a successful laparoscopic anterior resection in a patient with an intussusception caused by a sigmoid malignant tumor.

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Original Article
Analysis of Delayed Postpolypectomy Bleeding in a Colorectal Clinic
Do Hyoung Kim, Seok Won Lim
J Korean Soc Coloproctol. 2011;27(1):13-16.   Published online February 28, 2011
DOI: https://doi.org/10.3393/jksc.2011.27.1.13
  • 7,873 View
  • 46 Download
  • 8 Citations
AbstractAbstract PDF
Purpose

The colonoscopic polypectomy has become a valuable procedure for removing precursors of colorectal cancer, but some complications can be occurred. The most common complication after colonoscopic polypectomy is bleeding, which is reported to range from 1% to 6% and which can be immediate or delayed. Because the management of delayed postpolypectomy bleeding could be difficult, the use of preventive technique and reductions of risk factors are essential.

Methods

From January 2007 to December 2008, delayed hemorrhage occurred in 18 of the 1,841 polypectomy patients examined by one endoscopist. These cases were reviewed retrospectively for risk factors, pathologic findings, and treatment methods.

Results

Delayed bleeding occurred in 18/1,841 patients (0.95%). The mean age was 55.9 ± 10.9 years, and the male-to-female ratio was 8:1. The most common site was the right colon (11 cases, 61.1%), and the average polyp size was 9.2 ± 2.8 mm. Delayed bleeding was identified from 1 to 5 days after resection (mean, 1.6 ± 1.2 days). The most common macroscopic type of polyp was a sessile polyp (10 cases, 55.6%), and histologic finding was a tubular adenoma in 13 cases (72.2%). Seventeen cases were treated with clipping for hemostasis and 1 case with epinephrine injection.

Conclusion

The right colon and a sessile polyp were associated with an increase in delayed postpolypectomy bleeding. Reducing risk factors and close observation were essential in high risk patients, and prompt management with hemoclips was effective.

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    Enrique Rodríguez de Santiago, Sandra Pérez de la Iglesia, Diego de Frutos, José Carlos Marín-Gabriel, Carolina Mangas-SanJuan, Raúl Honrubia López, Hugo Uchima, Marta Aicart-Ramos, Miguel Ángel Rodríguez Gandía, Eduardo Valdivielso Cortázar, Felipe Ramos
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Case Report
Penetration of the Descending Colon by a Migrating Intrauterine Contraceptive Device
Jung Min Park, Chang Seog Lee, Min Seong Kim, Do Young Kim, Chul Young Kim, Young Bae Lim, Yong Kyu Lee, Dong Eun Park, Dong Hyun Lee
J Korean Soc Coloproctol. 2010;26(6):433-436.   Published online December 31, 2010
DOI: https://doi.org/10.3393/jksc.2010.26.6.433
  • 5,946 View
  • 41 Download
  • 7 Citations
AbstractAbstract PDF

Foreign bodies in the gastrointestinal tract often cause serious complications, such as perforation, obstruction, abscess formation, or hemorrhage. This is a case in which a patient visited our hospital and complained of a vague lower abdominal pain that had been present for three months. She had an intrauterine device (IUD) inserted five years earlier. The abdominal X-ray, computed tomography and colonoscopy revealed that the IUD had penetrated into the descending colon. We tried to remove the IUD by colonoscopy but failed due to pain, so we removed the IUD surgically. Thus, we report a case in which a previously inserted IUD had penetrated into the descending colon and was surgically removed. We also present a brief review of the literature.

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