Annals of Coloproctology

Original Articles

Complication

Early warning model to detect anastomotic leakage following colon surgery: a clinical observational study: Pooya Rajabaleyan, Ravish Jootun, Sören Möller, Ulrik Deding, Mark Bremholm Ellebæk, Issam al-Najami, Ian Lindsey; Ann Coloproctol. 2024;40(5):431-439. Published online October 8, 2024; DOI: https://doi.org/10.3393/ac.2023.00745.0106

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Purpose
We aimed to develop a predictive tool for anastomotic leakage (AL) following colon cancer surgery by combining a clinical early warning score (EWS) with the C-reactive protein (CRP) level.
Methods
The records of 1,855 patients who underwent colon cancer surgery at the Oxford University Hospitals NHS Foundation Trust between January 2013 and December 2018, with or without AL, were retrospectively reviewed. EWS and CRP levels were assessed daily from the first postoperative day until discharge. AL was defined as an anastomotic defect observed at reoperation, the presence of feculent fluid in a pelvic drain, or evidence of AL on computed tomography. The tool incorporated postoperative EWS and CRP levels for the accurate early detection of AL.
Results
From postoperative days 3 to 7, the mean CRP level exceeded 200 mg/L in patients with AL and was under 200 mg/L in those without AL (P<0.05). From postoperative days 1 to 5, the mean EWS among patients with leakage exceeded 2, while scores were below 2 among those without leakage (P<0.05). Receiver operating characteristic curve analysis identified postoperative day 3 as the most predictive of early leakage, with cutoff values of 2.4 for EWS and 180 mg/L for CRP; this yielded an area under the curve of 0.87 (sensitivity, 90%; specificity, 70%).
Conclusion
We propose using an EWS of 2.4 and a CRP level of 180 mg/L on postoperative day 3 following colon surgery with anastomosis as threshold values to prompt investigation and treatment of AL.

Citations

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Early detection of anastomotic leakage in colon cancer surgery: the role of early warning score and C-reactive protein
Gyung Mo Son
Annals of Coloproctology.2024; 40(5): 415. CrossRef
Predictive Biomarkers for the Early Detection of Anastomotic Leaks in Colorectal Surgeries: A Systematic Review
Wahidullah Dost, Mohammad Qaher Rasully , Mohammad Nazir Zaman, Wahida Dost, Wahida Ali, Sami A Ayobi, Raisa Dost, Jamaluddin Niazi, Kinza Bakht, Asma Iqbal, Syed Faqeer Hussain Bokhari
Cureus.2024;[Epub] CrossRef

Colorectal cancer

Evaluating prognostic significance of preoperative C-reactive protein to albumin ratio in older patients with pathological stage II or III colorectal cancer: Koji Numata, Yukari Ono, Mihwa Ju, Shizune Onuma, Ayano Tanaka, Taichi Kawabe, Sho Sawazaki, Akio Higuchi, Kazuki Yamanaka, Shinsuke Hatori, Hiroyuki Saeki, Hiroshi Matsukawa, Yasushi Rino, Kazuyuki Tani; Ann Coloproctol. 2024;40(2):161-168. Published online October 11, 2022; DOI: https://doi.org/10.3393/ac.2022.00367.0052

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Abstract PDF

Purpose
This study was performed to evaluate the prognostic value of preoperative C-reactive protein to albumin ratio (CAR) in older patients with colorectal cancer (CRC) undergoing curative resection.
Methods
We retrospectively analyzed 244 older patients (aged 75 years or higher) with pathological stage II or III CRC who underwent curative surgery between 2008 and 2016. The optimal value of CAR was calculated and its correlation with the clinicopathological factors and prognosis was examined.
Results
The optimal cutoff value of the CAR was 0.085. High preoperative CAR was significantly associated with high carcinoembryonic antigen levels (P=0.001), larger tumor size (P<0.001), and pT factor (P=0.001). On multivariate analysis, high CAR was independent prognostic factor for relapse-free survival (P=0.042) and overall survival (P=0.001).
Conclusion
Preoperative elevated CAR could be considered as an adverse predictor of both relapse-free survival and overall survival in older patients with CRC undergoing curative surgery.

Citations

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C-Reactive Protein/Albumin Ratio Is an Independent Risk Factor for Recurrence and Survival Following Curative Resection of Stage I–III Colorectal Cancer in Older Patients
Tomoaki Bekki, Manabu Shimomura, Minoru Hattori, Saki Sato, Atsuhiro Watanabe, Sho Ishikawa, Kouki Imaoka, Kosuke Ono, Keiso Matsubara, Tetsuya Mochizuki, Shintaro Akabane, Takuya Yano, Hideki Ohdan
Annals of Surgical Oncology.2024; 31(7): 4812. CrossRef
Towards a Gradual Optimization of Oncologic Prognostic Factors in the Era of the Frail Patient: The Potential Role of Preoperative Inflammation and Nutritional Status
Giuseppe Zimmitti
Annals of Surgical Oncology.2024; 31(8): 4853. CrossRef
Prognostic role of C-reactive protein to albumin ratio in cancer patients treated with immune checkpoint inhibitors: a meta-analysis
Menglu Dai, Wei Wu
Frontiers in Oncology.2023;[Epub] CrossRef
The association of blood biomarkers with treatment response and adverse health outcomes in older patients with solid tumors: A systematic review
Yara van Holstein, P. Janne E. van den Berkmortel, Stella Trompet, Diana van Heemst, Frederiek van den Bos, Marieke Roemeling-van Rhijn, Nienke A. de Glas, Marian Beekman, P. Eline Slagboom, Johanneke E.A. Portielje, Simon P. Mooijaart, Barbara C. van Mun
Journal of Geriatric Oncology.2023; 14(7): 101567. CrossRef
Prognostic prediction of colorectal cancer using the C-reactive protein to albumin ratio: the importance of inflammatory biomarkers and their association with long-term outcomes
Chul Seung Lee
Annals of Coloproctology.2023; 39(4): 287. CrossRef

Colorectal cancer

Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery: Masahiro Kataoka, Kuniyuki Gomi, Ken Ichioka, Takuya Iguchi, Tomoki Shirota, Arano Makino, Ko Shimada, Kiyotomi Maruyama, Motohiro Mihara, Shoji Kajikawa; Ann Coloproctol. 2023;39(4):315-325. Published online June 13, 2022; DOI: https://doi.org/10.3393/ac.2022.00234.0033

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Graphical Abstract Abstract PDF

Purpose
C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC).
Methods
Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (n=72/group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching.
Results
The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed.
Conclusion
In patients with CRC, CAR of POD 7 was a significant prognostic factor.

Citations

Citations to this article as recorded by

C-Reactive Protein/Albumin Ratio Is an Independent Risk Factor for Recurrence and Survival Following Curative Resection of Stage I–III Colorectal Cancer in Older Patients
Tomoaki Bekki, Manabu Shimomura, Minoru Hattori, Saki Sato, Atsuhiro Watanabe, Sho Ishikawa, Kouki Imaoka, Kosuke Ono, Keiso Matsubara, Tetsuya Mochizuki, Shintaro Akabane, Takuya Yano, Hideki Ohdan
Annals of Surgical Oncology.2024; 31(7): 4812. CrossRef
Prognostic impact of preoperative nutritional and immune inflammatory parameters on liver cancer
Sung Uk Bae
World Journal of Gastrointestinal Surgery.2024; 16(2): 266. CrossRef
Revisiting the diagnostic performance of exosomes: harnessing the feasibility of combinatorial exosomal miRNA profiles for colorectal cancer diagnosis
Jin Sung Park, Jin Ah Choi, Da Han Hyun, Chorok Byeon, Sang Gyu Kwak, Jun Seok Park, Seonki Hong
Discover Oncology.2024;[Epub] CrossRef
Impact of Postoperative Naples Prognostic Score to Predict Survival in Patients with Stage II–III Colorectal Cancer
Su Hyeong Park, Hye Seung Woo, In Kyung Hong, Eun Jung Park
Cancers.2023; 15(20): 5098. CrossRef
Applications of propensity score matching: a case series of articles published in Annals of Coloproctology
Hwa Jung Kim
Annals of Coloproctology.2022; 38(6): 398. CrossRef

Anorectal benign disease

The role of C-reactive protein ratio in predicting mortality in patients with Fournier gangrene: Ismail Cem Eray, Kubilay Dalci, Serdar Gumus, Orcun Yalav, Ahmet Gokhan Saritas, Asli Boz, Ahmet Rencuzogullari; Ann Coloproctol. 2023;39(3):223-230. Published online February 3, 2022; DOI: https://doi.org/10.3393/ac.2021.00843.0120

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Abstract PDF

Purpose
This study aimed to determine the C-reactive protein (CRP) ratio for the survival of patients with Fournier gangrene (FG).
Methods
Fifty-two patients with FG between January 2011 and September 2018 were retrospectively analyzed. Data on clinical presentation, Fournier Gangrene Severity Index (FGSI), CRP ratio, management, and outcome were analyzed. The CRP ratio was calculated as preoperative CRP/postoperative CRP value that measured 48 hours after surgical intervention. Possible alternative cutoff points for the FGSI and CRP were determined by receiver operating characteristic (ROC) analyses. The risk factors related to the prognosis were evaluated by univariate and multivariable logistic regression analyses.
Results
The mean CRP ratios were 6.7±6.6 in the survivor group and 1.2±0.8 in the nonsurvivor group (P=0.001). FGSI was significantly higher in the non-survivor group compared to survivor group (8.5±2.5 vs. 3.5±2.2, P=0.001). There was a negative correlation between FGSI and CRP ratio (r=–0.51). ROC analysis determined the cutoff value as 1.78 for CRP (sensitivity, 86%; specificity, 82%; area under the ROC curve, 0.90) to predict death. The incidence of death for patients with CRP ratio of ≤1.78 increased 26.7 fold for those with CRP ratio of >1.78 (95% confidence interval [CI], 4.8–146.5; P=0.001). In the multivariable logistic regression model, CRP ratio (odds ratio [OR], 10.3; 95% CI, 1.5–72.2; P=0.019) and FGSI (OR, 17.8; 95% CI, 2.6–121.1; P=0.003) were independent risk factors for death.
Conclusion
The CRP ratio is a simple method to use to predict mortality in FG.

Citations

Citations to this article as recorded by

Biomarkers to predict 30‐day mortality in patients with Fournier's gangrene disease: a retrospective study
Akile Zengin, Gokberk Alagas, Yusuf Murat Bag, Ahmet Murat Sendil, Ahmet Umit Cebeci, Elif Gundogdu, Yavuz Selim Angin, Mehmet Kılıc, Murat Ulas
ANZ Journal of Surgery.2025; 95(3): 433. CrossRef
The Value of Fournier’s Gangrene Scoring Systems on Admission to Predict Mortality: A Systematic Review and Meta-Analysis
Antonio Tufano, Piervito Dipinto, Francesco Passaro, Umberto Anceschi, Giorgio Franco, Rocco Simone Flammia, Flavia Proietti, Luca Antonelli, Giovanni Battista Di Pierro, Francesco Prata, Roberta Rullo, Sisto Perdonà, Costantino Leonardo
Journal of Personalized Medicine.2023; 13(9): 1283. CrossRef
Biomarkers to predict mortality in patients with Fournier’s gangrene admitted to the intensive care unit after surgery in South Korea
In Sik Shin, Seong Chan Gong, Sanghyun An, Kwangmin Kim
Acute and Critical Care.2023; 38(4): 452. CrossRef
Fournier's gangrene. Literature review
Débora Pattussi , Federico Carballo
AG Salud.2023; 1: 83. CrossRef
Delta neutrophil index as a prognostic factor for mortality in patients with Fournier's gangrene
In Sik Shin, Seong Chan Gong, Sanghyun An, Kwangmin Kim
International Journal of Urology.2022; 29(11): 1287. CrossRef

Benign GI diease

Factors Predicting the Need for Early Surgical Intervention for Small Bowel Obstruction: Young Jae Cho, In Seok Park, Jungbin Kim, Hyun Jin Cho, Geum Hee Gwak, Keun Ho Yang, Byung Noe Bae, Ki Hwan Kim; Ann Coloproctol. 2020;36(4):223-228. Published online January 31, 2020; DOI: https://doi.org/10.3393/ac.2019.09.30

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Abstract PDF

Purpose
Small bowel obstruction (SBO) is a common disease that requires hospitalization. The most common cause of SBO is postoperative adhesion. Delayed timing of operations in patients who need surgical intervention results in mortality or morbidity. A number of studies on SBO have established criteria for emergency surgery. However, few objective clinical parameters are available for screening patients who need a delayed operation. Therefore, we analyzed factors that affect the clinical course of SBO to select appropriate therapeutic plans for reducing the risk of complications in these patients.
Methods
We investigated the clinical characteristics of patients admitted to the surgery department of our hospital between January 1, 2015, and December 31, 2016, who were diagnosed with SBO. Patients were divided into an operative treatment group (n = 12) and a conservative treatment group (n = 96). We compared clinical characteristics between the 2 groups.
Results
The operative treatment group underwent more operations before SBO than the conservative treatment group (P = 0.007). Initial leukocyte counts (P = 0.004) and C-reactive protein (CRP) levels (P = 0.028) were elevated in the operative group. Body mass index (BMI) was lower in the operative group (P = 0.013).
Conclusion
The number of operations before SBO, leukocyte counts, CRP levels, and BMI were useful parameters for selecting patients who needed an urgent operation for SBO.

Citations

Citations to this article as recorded by

The predictive role of computed tomography with oral contrast in the successful management of adhesive small bowel obstruction
Mohamed Khattab, Amr Ayad, Sameh Aziz, Peter Alaa, Marie N. Grace, Mohamed Saber
The Egyptian Journal of Surgery.2024; 43(1): 16. CrossRef
Associated factors with non operative management failure in bowel obstruction
Omar Gutierrez Moreno, Nicolas Arredondo Mora, Oscar Rincon Barbosa, Francisco Gil Quintero
Surgery Open Digestive Advance.2024; 16: 100185. CrossRef
Preventable diagnostic errors of lower gastrointestinal perforation: a secondary analysis of a large-scale multicenter retrospective study
Taku Harada, Takashi Watari, Satoshi Watanuki, Seiko Kushiro, Taiju Miyagami, Syunsuke Syusa, Satoshi Suzuki, Tetsuya Hiyoshi, Suguru Hasegawa, Shigeki Nabeshima, Hidetoshi Aihara, Shun Yamashita, Masaki Tago, Fumitaka Yoshimura, Kotaro Kunitomo, Takahiro
International Journal of Emergency Medicine.2024;[Epub] CrossRef
Clinical and Radiological Factors Associated with Nonoperative Management Failure for Small Bowel Obstruction: A Retrospective Study from a Resource-Limited Setting
Saleh Al-wageeh, Qasem Alyhari, Faisal Ahmed, Hanan Mohammed, Noha Dahan, Abdullatif Almohtadi, Sameer AL-Nuzili, Mohamed Badheeb, Abdulsattar Naji
Therapeutics and Clinical Risk Management.2024; Volume 20: 893. CrossRef
Development of a predictive model for the need for early surgery in patients with adhesive small-bowel obstruction
Yanhao Sun, Yilong Hu, Yuanfang Sun
Journal of International Medical Research.2024;[Epub] CrossRef
Predictive factors for operative intervention and ideal length of non-operative trial in adhesive small bowel obstruction
Tara van Veen, Purushotham Ramanathan, Lolita Ramsey, Jonathan Dort, Dina Tabello
Surgical Endoscopy.2023; 37(11): 8628. CrossRef
Surgical management of adhesive small bowel obstruction: Is it still mandatory to wait? – An update
R. Demessence, Y. Lyoubi, F. Feuerstoss, A. Hamy, C. Aubé, A. Paisant, A. Venara
Journal of Visceral Surgery.2022; 159(4): 309. CrossRef
Prise en charge chirurgicale des syndromes occlusifs de l’intestin grêle sur bride et adhérences postopératoires : faut-il toujours attendre ?
R. Demessence, Y. Lyoubi, F. Feuerstoss, A. Hamy, C. Aubé, A. Paisant, A. Venara
Journal de Chirurgie Viscérale.2022; 159(4): 326. CrossRef
Small bowel obstruction
David J. Detz, Jerica L. Podrat, Jose C. Muniz Castro, Yoon K. Lee, Feibi Zheng, Shawn Purnell, Kevin Y. Pei
Current Problems in Surgery.2021; 58(7): 100893. CrossRef

Diagnostic Value of C-reactive Protein in Complicated Appendicitis: Hyoung-Min Moon, Beom-Seok Park, Duk-Jin Moon; J Korean Soc Coloproctol. 2011;27(3):122-126. Published online June 30, 2011; DOI: https://doi.org/10.3393/jksc.2011.27.3.122

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Abstract PDF

Purpose

Early detection of appendicitis has increased due to development of computed tomography and ultrasonography, yet we are frequently meeting complicated appendicitis, including perforation, abscess and a gangrenous appendicitis due to delayed diagnosis. For that reason, we want to evaluate predictive factors for the complicated appendicitis.

Methods

A total of 128 patients with appendicitis, after 13 patients with a duration of under 12 hours and 15 patients with pathological non-appendicitis were excluded from 156 patients, who visited Kwangju Christian Hospital from November 2008 to November 2010 were retrospectively reviewed.

Results

There were 62 patients (48.3%) with simple appendicitis and 66 patients (51.7%) with complicated appendicitis. In univariate analysis, age (P < 0.001), C-reactive protein (P < 0.001) and the diameter of the appendix (P = 0.006), were found to be significant. Multivariate analysis demonstrated that C-reactive protein was an independent predictor for complicated appendicitis (odds ratio, 1.371; 95% confidence interval, 1.155 to 1.628; P < 0.001). The cut-off value of C-reactive protein was set at 7.05 mg/dL by using receiver operating characteristic curve (0.805; sensitivity, 57.6%; specificity, 98.3%).

Conclusion

This study suggests that if C-reactive protein is above 7.05 mg/dL, immediate and proper management should be performed due to a high probability of complicated appendicitis, especially in young children or elderly patients who frequently present with vague symptoms.

Citations

Citations to this article as recorded by

Clinical prediction model for gangrenous appendicitis: A retrospective single-center study
Toshiyuki Suzuki, Akiyo Matsumoto, Daisuke Sugiki, Takahiko Akao, Hiroshi Matsumoto
Scandinavian Journal of Surgery.2025;[Epub] CrossRef
Usefulness of extended inflammatory parameters related to neutrophil activation reported by Sysmex XN-1000 hematology analyzer for predicting complicated acute appendicitis. Comparison with canonical inflammatory laboratory tests
María Isabel Díaz López, Elena Crespo Álvarez, Álvaro Martínez Manzano, Eloísa Urrechaga, Manuel Tomás Orgaz Morales, Mercedes González Morales, Elena Martín García, Luis García de Guadiana-Romualdo
Cirugía Española (English Edition).2024; 102(6): 300. CrossRef
Usefulness of extended inflammatory parameters related to neutrophil activation reported by Sysmex XN-1000 hematology analyzer for predicting complicated acute appendicitis. Comparison with canonical inflammatory laboratory tests
María Isabel Díaz López, Elena Crespo Álvarez, Álvaro Martínez Manzano, Eloísa Urrechaga, Manuel Tomás Orgaz Morales, Mercedes González Morales, Elena Martín García, Luis García de Guadiana-Romualdo
Cirugía Española.2024; 102(6): 300. CrossRef
A Case-control Study on the Correlation between Serum Bilirubin Levels and Various Types of Appendicitis
Hamzeh Mohammadi Sardoo, Fatemeh Sadat Mir Rashidi, Benyamin Fallah Kohan, Nasim Dehdashti, Ayuob Shokoufamanesh, Rasoul Raesi, Kiavash Hushmandi, Salman Daneshi
The Open Public Health Journal.2024;[Epub] CrossRef
Predictive efficacy of immature granulocytes in acute complicated appendicitis
Merve Yazla, Burcu Kadıoğlu, Hacer Demirdelen, Fatih Mehmet Aksoy, Erdem Özkan, Burak Katipoğlu
Revista da Associação Médica Brasileira.2024;[Epub] CrossRef
Predicting complicated appendicitis is possible without the use of sectional imaging—presenting the NoCtApp score
Jens Strohäker, Martin Brüschke, You-Shan Feng, Christian Beltzer, Alfred Königsrainer, Ruth Ladurner
International Journal of Colorectal Disease.2023;[Epub] CrossRef
Individual biomarkers in the blood are not yet applicable in diagnosing complicated appendicitis: A scoping review
Binyamin Sikander, Jacob Rosenberg, Siv Fonnes
The American Journal of Emergency Medicine.2023; 67: 100. CrossRef
MONOCYTE DISTRIBUTION WIDTH; CAN IT BE USED AS AN EARLY DIAGNOSIS MARKER IN CASES OF ACUTE COMPLICATED APPENDICITIS? A PRELIMINARY STUDY
Koray KOŞMAZ, Abdullah DURHAN, Abdullah ŞENLİKCİ, Marlen SÜLEYMAN, Can ERSAK, Ender ERGÜDER, Yusuf Murat BAG, Mehmet ŞENEŞ, Mevlüt Recep PEKCİCİ
Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi.2022; 54(3): 424. CrossRef
Inflammatory parameters as predictive factors for complicated appendicitis: A retrospective cohort study
Ana Matos Ribeiro, Inês Romero, Carlos Costa Pereira, Filomena Soares, Álvaro Gonçalves, Susana Costa, João Barros da Silva
Annals of Medicine and Surgery.2022; 74: 103266. CrossRef
Comment to: “Inflammatory parameters as predictive factors for complicated appendicitis: A retrospective cohort study’’
Rıfat Peksöz, Yavuz Albayrak, Sabri Selçuk Atamanalp
Annals of Medicine and Surgery.2022; 75: 103391. CrossRef
The potential role of interleukin-6, endotoxin and C-reactive protein as standard biomarkers for acute appendicitis in adults
Sasa Dimic, Ivana Dimic, Zlatan Elek, Milan Radojkovic
Srpski arhiv za celokupno lekarstvo.2022; 150(3-4): 163. CrossRef
Characteristics of Patients Presented with Complicated Appendicitis in Adama, Ethiopia: A Cross-Sectional Study
Haset Dagne, Tsega-Ab Abebaw
Open Access Emergency Medicine.2022; Volume 14: 573. CrossRef
Conversion rate and risk factors of conversion to open in laparoscopic appendicectomy
Nelson Rao Pushpanathan, Mohd Nizam Md Hashim, Zalina Zahari, Syed Hassan Syed Abd. Aziz, Wan Zainira Wan Zain, Rosnelifaizur Ramely, Michael Pak-Kai Wong, Ikhwan Sani Mohamad, Wan Mokhzani Wan Mokhter, Maya Mazuwin Yahya, Siti Rahmah Hashim Isa Merican,
Annals of Coloproctology.2022; 38(6): 409. CrossRef
Comparison of Outer Diameter of Appendix, C-reactive Protein, and Serum Bilirubin Levels in Complicated Versus Uncomplicated Appendicitis
Dhanish Parekh, Dinesh Jain, Saurabh Mohite, Deepak Phalgune
Indian Journal of Surgery.2020; 82(3): 314. CrossRef
RIPASA and air scoring systems are superior to alvarado scoring in acute appendicitis: Diagnostic accuracy study
Meer M. Chisthi, Anilkumar Surendran, Jiju Therumpurathu Narayanan
Annals of Medicine and Surgery.2020; 59: 138. CrossRef
Risk factors for serious morbidity, prolonged length of stay and hospital readmission after laparoscopic appendectomy - results from Pol-LA (Polish Laparoscopic Appendectomy) multicenter large cohort study
Maciej Walędziak, Anna Lasek, Michał Wysocki, Michael Su, Maciej Bobowicz, Piotr Myśliwiec, Kamil Astapczyk, Mateusz Burdzel, Karolina Chruściel, Rafał Cygan, Wojciech Czubek, Natalia Dowgiałło-Wnukiewicz, Jakub Droś, Paula Franczak, Wacław Hołówko, Artur
Scientific Reports.2019;[Epub] CrossRef
Utility of the immature granulocyte percentage for diagnosing acute appendicitis among clinically suspected appendicitis in adult
Jae‐Sang Park, June‐Sung Kim, Youn‐Jung Kim, Won Young Kim
Journal of Clinical Laboratory Analysis.2018;[Epub] CrossRef
ROLE OF C REACTIVE PROTEIN AND WBC COUNT IN THE DIAGNOSIS OF ACUTE APPENDICITIS AND ITS PREDICTIVE VALUE IN ASSESSING THE SEVERITY OF THE DISEASE
Jeyaraman V, Arjun Pon Avudaiappan
Journal of Evidence Based Medicine and Healthcare.2017; 4(5): 248. CrossRef
A scoring system to predict the severity of appendicitis in children
Ramon R. Gorter, Anne Loes van den Boom, Hugo A. Heij, C.M. Frank Kneepkens, Caroline C. Hulsker, Mark Tenhagen, Imro Dawson, Johanna H. van der Lee
Journal of Surgical Research.2016; 200(2): 452. CrossRef
Surgeon's clinical valuation and accuracy of ultrasound in the diagnosis of acute appendicitis: A comparison with intraoperative evaluation. Five years experience
Alessia Ferrarese, Alessandro Falcone, Mario Solej, Dario Bono, Paolo Moretto, Najada Dervishi, Veltri Andrea, Stefano Enrico, Mario Nano, Valter Martino
International Journal of Surgery.2016; 33: S45. CrossRef
Is preoperative distinction between complicated and uncomplicated acute appendicitis feasible without imaging?
Elina Lietzén, Jari Mällinen, Juha M. Grönroos, Tero Rautio, Hannu Paajanen, Pia Nordström, Markku Aarnio, Tuomo Rantanen, Juhani Sand, Jukka-Pekka Mecklin, Airi Jartti, Johanna Virtanen, Pasi Ohtonen, Paulina Salminen
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The impact of disease severity, age and surgical approach on the outcome of acute appendicitis in children
A. L. van den Boom, R. R. Gorter, P. M. M. van Haard, P. G. Doornebosch, H. A. Heij, I. Dawson
Pediatric Surgery International.2015; 31(4): 339. CrossRef
Could C-Reactive Protein be a Potential Biomarker of Complicated Acute Appendicitis?
Cy Lai, Yk Leung, Ca Graham
Hong Kong Journal of Emergency Medicine.2014; 21(6): 354. CrossRef

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