Annals of Coloproctology

Display

Sort by :

Original Article

Pulmonary Resection for Metastases from Colorectal Cancer: Prognostic Factors and Survival.: Yi, Loo Ji , Lee, Won Suk , Yun, Seong Hyeon , Chun, Ho Kyung , Lee, Woo Yong , Yun, Hae Ran , Kim, Jhin Gook , Kim, Kwhan Mien , Shim, Young Mog; J Korean Soc Coloproctol. 2007;23(1):53-59.; DOI: https://doi.org/10.3393/jksc.2007.23.1.53

2,289 View
10 Download
1 Citations

PURPOSE
Pulmonary metastases occur in up to 10% of all patients who undergo a curative resection for colorectal cancer. Surgical resection is an important part in the treatment of pulmonary metastasis from colorectal cancer. We analyzed the treatment outcome and the prognostic factors affecting survival in this subset of patients.
METHODS
Between October 1994 and December 2004, 59 patients underwent a curative resection for pulmonary metastases from colorectal cancer. Uncontrollable synchronous liver and lung metastasis or synchronous colorectal cancers with isolated lung metastasis were excluded from this study. A retrospective review of the patients' characteristics and of factors influencing survival was performed. Survival was analyzed by using the Kaplan-Meier method. Comparisons between the groups were performed by using a log-rank analysis and the Cox proportional hazard model.
RESULTS
The 5-year overall survival rate of all patients who received a pulmonary resection was 50.3%. The number of pulmonary metastases was significantly related with survival (P=0.032). A pre-thoracotomy CEA level exceeding 5 ng/ml was related with poor survival (P=0.001). A disease- free interval of greater than 2 years did not correlate with survival after a thoracotomy (P=0.3).
CONCLUSIONS
The pre-thoracotomy CEA level and the number of metastases were independent prognostic factors. Resection of a pulmonary metastasis from colorectal cancer may result in improved survival or even cure in selected patients. A pulmonary resection of colorectal cancer is regarded as a safe and effective treatment with low morbidity and mortality rates.

Citations

Citations to this article as recorded by

Surgical Resection for Lung Metastases from Colorectal Cancer
Hyung Jin Kim, Bong-Hyeon Kye, Jae Im Lee, Sang Chul Lee, Yoon Suk Lee, In Kyu Lee, Won Kyung Kang, Hyeon-Min Cho, Seok Whan Moon, Seong Taek Oh
Journal of the Korean Society of Coloproctology.2010; 26(5): 354. CrossRef

First
Prev
Page of 1
Next
Last

Search