Annals of Coloproctology

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Aluminum Potassium Sulfate and Tannic Acid Injection for Hemorrhoids: Seok Won Lim; J Korean Soc Coloproctol. 2012;28(2):73-77. Published online April 30, 2012; DOI: https://doi.org/10.3393/jksc.2012.28.2.73

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A quick hemostatic effect, as well as sclerosing and shrinkage of hemorrhoids, can be attained when internal hemorrhoids are treated by using injection therapy with aluminum potassium sulfate and tannic acid (ALTA), the outcomes of treatment may be similar to those of a hemorrhoidectomy. However, if the type of hemorrhoid or the method of injection is not appropriate for ALTA treatment, complications peculiar to ALTA or recurrence may develop. Accordingly, sufficient understanding of the treatment mechanism of ALTA injection and repeated training for injection are required for effective use of the ALTA treatment.

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Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy for hemorrhoidal disease: a systematic review and meta-analysis
Vasiliki Manaki, Vangelis Bontinis, Alkis Bontinis, Argirios Giannopoulos, Ioannis Kontes, Angeliki Chorti, Kiriakos Ktenidis
Acta Chirurgica Belgica.2024; 124(4): 253. CrossRef
Efficacy and Safety of a New Technique Combining Injection Sclerotherapy and External Hemorrhoidectomy for Prolapsed Hemorrhoids: A Single-center Observational Study
Tatsuya Abe, Masao Kunimoto, Yoshikazu Hachiro, Akane Ito, Kenji Watanabe, Shigenori Ota, Kei Ohara, Mitsuhiro Inagaki, Yusuke Saitoh, Masanori Murakami
Journal of the Anus, Rectum and Colon.2024; 8(4): 331. CrossRef
ANTI-HEMORRHOIDAL ACTIVITY OF AYURVEDIC CREAM IN RATS
Anil T. Pawar, Chinmay D. Deshmukh, Digambar K. Jadhav, Ranganath R. Kulkarni
INDIAN DRUGS.2023; 60(01): 84. CrossRef
Injection of aluminum potassium sulfate and tannic acid in the treatment of fecal incontinence: a single-center observational study
Tatsuya Abe, Masao Kunimoto, Yoshikazu Hachiro, Kei Ohara, Mitsuhiro Inagaki
Annals of Coloproctology.2022; 38(6): 403. CrossRef
Sklerosierungstherapie
Alex Furtwängler
coloproctology.2020; 42(1): 14. CrossRef
Effectiveness of Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid as a Non-Surgical Treatment for Internal Hemorrhoids
Yuichi Tomiki, Jun Aoki, Shunsuke Motegi, Rina Takahashi, Toshiaki Hagiwara, Yu Okazawa, Kosuke Mizukoshi, Masaya Kawai, Shinya Munakata, Shun Ishiyama, Kiichi Sugimoto, Kazuhiro Sakamoto
Clinical Endoscopy.2019; 52(6): 581. CrossRef
Taste of phytocompounds: A better predictor for ethnopharmacological activities of medicinal plants than the phytochemical class?
Dorin Dragos, Marilena Gilca
Journal of Ethnopharmacology.2018; 220: 129. CrossRef
Changes in anorectal physiology following injection sclerotherapy using aluminum potassium sulfate and tannic acid versus transanal repair in patients with symptomatic rectocele; a retrospective cohort study
Joo Hyung Kim, Yong Pyo Lee, Kwang Wook Suh
BMC Surgery.2018;[Epub] CrossRef
Extraoral Taste Receptor Discovery: New Light on Ayurvedic Pharmacology
Marilena Gilca, Dorin Dragos, Marco Leonti
Evidence-Based Complementary and Alternative Medicine.2017;[Epub] CrossRef
Liver injury after aluminum potassium sulfate and tannic acid treatment of hemorrhoids
Kenichi Yoshikawa, Reimi Kawashima, Yuki Hirose, Keiko Shibata, Takafumi Akasu, Noriko Hagiwara, Takeharu Yokota, Nami Imai, Akira Iwaku, Go Kobayashi, Hirohiko Kobayashi, Akiyoshi Kinoshita, Nao Fushiya, Hiroyuki Kijima, Kazuhiko Koike, Masayuki Saruta
World Journal of Gastroenterology.2017; 23(27): 5034. CrossRef
Treatment of Internal Hemorrhoids by Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid
Yuichi Tomiki, Seigo Ono, Jun Aoki, Rina Takahashi, Shun Ishiyama, Kiichi Sugimoto, Yukihiro Yaginuma, Yutaka Kojima, Michitoshi Goto, Atsushi Okuzawa, Kazuhiro Sakamoto
Diagnostic and Therapeutic Endoscopy.2015; 2015: 1. CrossRef
Aluminum Potassium Sulfate and Tannic Acid - A New Option for the Treatment of Grade 3 Hemorrhoids
Yong Hee Hwang
Annals of Coloproctology.2015; 31(3): 83. CrossRef
Comparison of Injection Sclerotherapy Between 5% Phenol in Almond Oil and Aluminum Potassium Sulfate and Tannic Acid for Grade 3 Hemorrhoids
Takaaki Yano, Kenji Yano
Annals of Coloproctology.2015; 31(3): 103. CrossRef
Distal Hemorrhoidectomy With ALTA Injection: A New Method for Hemorrhoid Surgery
Tatsuya Abe, Yoshikazu Hachiro, Yoshiaki Ebisawa, Houhei Hishiyama, Masao Kunimoto
International Surgery.2014; 99(3): 295. CrossRef

Original Article

The Effect after Intra-dermal Methylene Blue, Hydrocortisone, Lidocaine Injection Therapy for Intractable, Idiopathic Pruritus Ani.: Kim, Joo Hyung , Lee, Yong Pyo; J Korean Soc Coloproctol. 2005;21(2):71-75.

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Abstract PDF: PURPOSE
Idiopathic pruritus ani is a common and embarrassing proctological condition which can be very difficult to treat. In this study, we documented our results with methylene blue intra-dermal injection in patients with intractable idiopathic pruritus ani.
METHODS
5-ml 1% methylene blue, 100-mg hydrocortisone, and 15-ml 1% lidocaine were injected into the perianal skin of 21 patients with idiopathic pruritus ani which had proved refractory to standard care. Clinical follow-up was undertaken.
RESULTS
After one injection of the above solution, 15 (71.4%) of the patients were rendered symptom free. Repeat injection in the initial non- responders ultimately rendered another four. 19 (total: 90.5 %) of the patrents symptom free. Morbidity was 0%.
CONCLUSION
This study has shown that intra-dermal methylene blue injection is a safe, simple, and efficient method of treating intractable, idiopathic pruritus ani.

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