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Case Reports
Malignant disease,Rare disease & stoma,Complication
Colonic Perforation After Treatment With Nivolumab in Esophageal Cancer: A Case Report
Hye Jung Cho, Woo Ram Kim, Joo-Hang Kim, Duk Hwan Kim, Dae Jung Kim, Haeyoun Kang
Ann Coloproctol. 2021;37(Suppl 1):S39-S43.   Published online June 24, 2021
DOI: https://doi.org/10.3393/ac.2020.00213.0030
  • 3,790 View
  • 90 Download
  • 5 Web of Science
  • 6 Citations
AbstractAbstract PDF
With the advent of checkpoint inhibitors, it has opened up opportunities for numerous cancer patients. However, as is the case with every treatment, complications need to be weighed. Gastrointestinal adverse effects, such as diarrhea and colitis are well-known complications for checkpoint inhibitors. In severe cases, colitis-induced colonic perforation may occur with an estimation of 1.0% to 1.5% in anti-CTLA-4 antibodies. However, only a handful of cases of such devastating complications have been reported in anti-PD-1 antibodies such as pembrolizumab and nivolumab. We here report a case of intestinal perforation in a patient treated with nivolumab.

Citations

Citations to this article as recorded by  
  • Chemotherapy-associated pneumoperitoneum in cancer patients: a scoping review
    Renee M. Maina, Caroline Rader, Jeevan Kypa, Constantine Asahngwa, Hilary M. Jasmin, Nia N. Zalamea, John S. Nelson, Jonathan L. Altomar, Mary Brinson Owens, Clarisse S. Muenyi, Denis A. Foretia
    Annals of Medicine & Surgery.2024;[Epub]     CrossRef
  • Gastrointestinal perforation associated with novel antineoplastic agents: A real-world study based on the FDA Adverse Event Reporting System
    Zicheng Yu, Haibin Zhu, Hongjun Chen, Lifei Zhu, Xiaolan Liao
    Journal of Pharmacy & Pharmaceutical Sciences.2023;[Epub]     CrossRef
  • Gastrointestinal and Hepatobiliary Immune-related Adverse Events: A Histopathologic Review
    Zainab I. Alruwaii, Elizabeth A. Montgomery
    Advances in Anatomic Pathology.2023; 30(3): 230.     CrossRef
  • An updated review of gastrointestinal toxicity induced by PD-1 inhibitors: from mechanisms to management
    Yiyu Cheng, Fangmei Ling, Junrong Li, Yidong Chen, Mingyang Xu, Shuang Li, Liangru Zhu
    Frontiers in Immunology.2023;[Epub]     CrossRef
  • Nivolumab

    Reactions Weekly.2022; 1892(1): 181.     CrossRef
  • Gastrointestinal and Hepatobiliary Immune-related Adverse Events: A Histopathologic Review
    Zainab I. Alruwaii, Elizabeth A. Montgomery
    Advances in Anatomic Pathology.2022; 29(4): 183.     CrossRef
Benign GI diease
Small Bowel Perforation Associated With Gastrointestinal Graft-Versus-Host Disease and Cytomegalovirus Enteritis in a Patient With Leukemia: A Case Report With Literature Review
Kwang-Seop Song, Min Jung Kim, Han-Ki Lim, Yoon Hwa Hong, Sung Sil Park, Chang Won Hong, Sung Chan Park, Dae Kyung Sohn, Kyung Su Han, Jae Hwan Oh
Ann Coloproctol. 2020;36(4):281-284.   Published online August 31, 2020
DOI: https://doi.org/10.3393/ac.2018.10.01.1
  • 3,281 View
  • 88 Download
  • 1 Web of Science
  • 1 Citations
AbstractAbstract PDF
Gastrointestinal graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation. Concomitant cytomegalovirus (CMV) enteritis worsens the prognosis of this condition. We report a case of small bowel perforation associated with gastrointestinal GVHD and CMV enteritis in a patient with leukemia who was successfully treated surgically. A 39-year-old man presented with intestinal perforation necessitating emergency surgical intervention. He was diagnosed with T-cell acute lymphoblastic leukemia and developed severe gastrointestinal GVHD and CMV enteritis after hematopoietic stem cell transplantation. His terminal ileum showed a perforation with diffuse wall thinning, and petechiae were observed over long segments of the distal ileum and the proximal colon. Small bowel segmental resection and a subtotal colectomy with a double-barreled ileocolostomy were performed. The patient recovered uneventfully after the operation. Based on reports described in the literature, surgery plays a minor role in the management of gastrointestinal GVHD; however, timely surgical intervention could be effective in selected patients.

Citations

Citations to this article as recorded by  
  • Cytomegalovirus enteritis resistant to antiviral drugs improved following total colectomy
    Sae Kawata, Jumpei Takamatsu, Yuichi Yasue, Aya Fukuhara, Jinkoo Kang
    Surgical Case Reports.2023;[Epub]     CrossRef
Benign GI diease,Rare disease & stoma,Complication
Intestinal Perforation as a Paradoxical Reaction to Antitubercular Therapy: A Case Report
Sung Hoon Kang, Hee Seok Moon, Jae Ho Park, Ju Seok Kim, Sun Hyung Kang, Eaum Seok Lee, Seok Hyun Kim, Byung Seok Lee, Jae Kyu Sung, Hyun Yong Jeong, Kyung Ha Lee
Ann Coloproctol. 2021;37(Suppl 1):S18-S23.   Published online May 15, 2020
DOI: https://doi.org/10.3393/ac.2020.03.16.1
  • 3,759 View
  • 113 Download
  • 2 Web of Science
  • 4 Citations
AbstractAbstract PDF
Paradoxical reactions to tuberculosis (TB) treatment are characterized by an initial improvement of the clinical symptoms followed by clinical or radiological deterioration of existing tuberculous lesions, or by development of new lesions. Intestinal perforation in gastrointestinal TB can occur as a paradoxical reaction to antitubercular therapy. A 55-year-old man visited the outpatient department with lower abdominal pain and weight loss. He was diagnosed with intestinal TB and started antitubercular therapy. After 3 months of antitubercular therapy, a colonoscopy revealed improvement of the disease. Three days after the colonoscopy, the patient visited the emergency room complaining of abdominal pain. Abdominal computed tomography revealed extraluminal air-filled spaces in the pelvic cavity. We diagnosed a small bowel perforation and performed an emergency laparotomy and a right hemicolectomy with small bowel resection. This report describes the case of intestinal perforation presenting as a paradoxical reaction to antitubercular and provides a brief literature review.

Citations

Citations to this article as recorded by  
  • Réaction paradoxale tuberculeuse
    L.-D. Azoulay, A.-L. Houist, E. Feredj, W. Vindrios, S. Gallien
    La Revue de Médecine Interne.2024; 45(5): 279.     CrossRef
  • Left hand abscess as a paradoxical reaction during treatment of disseminated tuberculosis in immunocompetent patient: case report and review of literature
    Aisha Alharbi, Aseel Aljahdali, Mohamed Firoze Ahamed, Hassan Almarhabi
    BMC Infectious Diseases.2024;[Epub]     CrossRef
  • Paradoxical Reaction to Antitubercular Treatment Causing Colonic Obstruction
    Akira Hokama, Yuiko Oishi, Erika Koga, Sayuri Takehara, Jiro Fujita
    Chonnam Medical Journal.2022; 58(1): 52.     CrossRef
  • Multiple drugs

    Reactions Weekly.2021; 1881(1): 189.     CrossRef
Original Articles
Predictors of Morbidity and Mortality After Surgery for Intestinal Perforation
Rumi Shin, Sang Mok Lee, Beonghoon Sohn, Dong Woon Lee, Inho Song, Young Jun Chai, Hae Won Lee, Hye Seong Ahn, In Mok Jung, Jung Kee Chung, Seung Chul Heo
Ann Coloproctol. 2016;32(6):221-227.   Published online December 31, 2016
DOI: https://doi.org/10.3393/ac.2016.32.6.221
  • 8,866 View
  • 80 Download
  • 32 Web of Science
  • 34 Citations
AbstractAbstract PDF
Purpose

An intestinal perforation is a rare condition, but has a high mortality rate, even after immediate surgical intervention. The clinical predictors of postoperative morbidity and mortality are still not well established, so this study attempted to identify risk factors for postoperative morbidity and mortality after surgery for an intestinal perforation.

Methods

We retrospectively analyzed the cases of 117 patients who underwent surgery for an intestinal perforation at a single institution in Korea from November 2008 to June 2014. Factors related with postoperative mortality at 1 month and other postoperative complications were investigated.

Results

The mean age of enrolled patients was 66.0 ± 15.8 years and 66% of the patients were male. Fifteen patients (13%) died within 1 month after surgical treatment. Univariate analysis indicated that patient-related factors associated with mortality were low systolic and diastolic blood pressure, low serum albumin, low serum protein, low total cholesterol, and high blood urea nitrogen; the surgery-related factor associated with mortality was feculent ascites. Multivariate analysis using a logistic regression indicated that low systolic blood pressure and feculent ascites independently increased the risk for mortality; postoperative complications were more likely in both females and those with low estimated glomerular filtration rates and elevated serum C-reactive protein levels.

Conclusion

Various factors were associated with postoperative clinical outcomes of patients with an intestinal perforation. Morbidity and mortality following an intestinal perforation were greater in patients with unstable initial vital signs, poor nutritional status, and feculent ascites.

Citations

Citations to this article as recorded by  
  • In Situ 4D Printing of Polyelectrolyte/Magnetic Composites for Sutureless Gastric Perforation Sealing
    Yunsong Shi, Sihan Tang, Xi Yuan, Zhuofan Li, Shifeng Wen, Zhongwei Li, Bin Su, Chunze Yan, Lili Chen
    Advanced Materials.2024;[Epub]     CrossRef
  • Small Intestinal Perforation after 360-Degree Liposuction: A Case Report
    Jenna C. Bekeny, Samuel S. Huffman, Chris Thomas, Mariana Tumminello, Anna Kata, Rajiv Parikh, Laura K. Tom, Grant M. Kleiber
    Aesthetic Plastic Surgery.2024; 48(5): 946.     CrossRef
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    Forrest Bohler, Allison Garden
    Journal of Osteopathic Medicine.2024; 124(1): 39.     CrossRef
  • Prevalence, Pattern, Mortality, and Morbidity of Traumatic Small Bowel Perforation at King Abdulaziz Medical City: A Retrospective Cohort Study
    Fahad Aljehaiman, Faisal J Almalki, Abdulah Alhusain, Faris Alsalamah, Khaled Alzahrani, Abdulkareem Alharbi, Hani Alkhulaiwi
    Cureus.2024;[Epub]     CrossRef
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    Danier Ong, Rajiv Yogendran, Emily Fite
    Journal of the American College of Emergency Physicians Open.2024;[Epub]     CrossRef
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    Giuleta Jamsari, James Wei Tatt Toh
    Laparoscopic, Endoscopic and Robotic Surgery.2024; 7(3): 128.     CrossRef
  • Emergent Esophagectomy in Patients with Esophageal Malignancy Is Associated with Higher Rates of Perioperative Complications but No Independent Impact on Short-Term Mortality
    Yahya Alwatari, Devon C. Freudenberger, Jad Khoraki, Lena Bless, Riley Payne, Walker A. Julliard, Rachit D. Shah, Carlos A. Puig
    Journal of Chest Surgery.2024; 57(2): 160.     CrossRef
  • Urea to Albumin Ratio Is an Excellent Predictor of Death in Patients With Complicated Intra-Abdominal Infections
    Evgeni Dimitrov, Krasimira Halacheva, Georgi Minkov, Emil Enchev, Yovcho Yovtchev
    Surgical Infections.2024; 25(3): 225.     CrossRef
  • Postoperative Complications in Emergency Surgeries at a Referral Hospital in Eastern Venezuela
    Victor Castañeda-Marquez, Yeisson Rivero-Moreno, Enrique Avila-Liendo, Gabriel Gonzalez-Quinde, Wilson Garcia-Cazorla, Georcimar Mendez-Meneses, Yoalkris E Salcedo, Tamara Rodriguez-Rugel, Jackner Antigua-Herrera, Miguel Rivas-Perez, Silvia Agudelo-Mendoz
    Cureus.2024;[Epub]     CrossRef
  • Gastrointestinal tract perforation after radiofrequency ablation for hepatic tumor: Incidence and risk factors
    Kyowon Gu, Tae Wook Kang, Seungchul Han, Dong Ik Cha, Kyoung Doo Song, Min Woo Lee, Hyunchul Rhim, Go Eun Park
    European Journal of Radiology.2024; 177: 111560.     CrossRef
  • Revisiting Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM) and Portsmouth-POSSUM (P-POSSUM) Scores: Are They Valid in Cases of Ileal Perforation?
    Saikrishna Eswaravaka, Chirantan Suhrid, Bhavya Rao, Sundaresh Prabhakar, Jayashri Pandya
    Cureus.2024;[Epub]     CrossRef
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    M. Forooghi, R. Shahrokhi, Sh. Yousufzai
    International Journal of Surgery Case Reports.2024; 123: 110283.     CrossRef
  • Factors related to cardiac rupture after acute myocardial infarction
    Xue Gao, Ying Guo, Xiaoting Zhu, Chunlei Du, Beibei Ma, Yinghua Cui, Shuai Wang
    Frontiers in Cardiovascular Medicine.2024;[Epub]     CrossRef
  • Investigating the association between osteopenia and bowel perforation through a multicenter radiologic analysis
    Sebastian Sanduleanu, Koray Ersahin, Jonathan Kottlors, Johannes Bremm, Narmin Talibova, Tim Damer, Merve Erdogan, Nils Groβe Hokamp, Lukas Goertz, Nijat Nasirov, Vilayat Valiyev, Christiane Bruns, David Maintz, Nuran Abdullayev
    Scientific Reports.2024;[Epub]     CrossRef
  • Characteristics, treatment, and outcome of patients with bowel perforation after immune checkpoint inhibitor exposure
    Antonio Pizuorno Machado, Malek Shatila, Cynthia Liu, Yang Lu, Mehmet Altan, Isabella C. Glitza Oliva, Dan Zhao, Hao Chi Zhang, Anusha Thomas, Yinghong Wang
    Journal of Cancer Research and Clinical Oncology.2023; 149(9): 5989.     CrossRef
  • Abdominal emergency surgery in patients with hematological malignancies: a retrospective single-center analysis
    Philipp H. von Kroge, Anna Duprée, Oliver Mann, Jakob R. Izbicki, Jonas Wagner, Paymon Ahmadi, Sören Weidemann, Raissa Adjallé, Nicolaus Kröger, Carsten Bokemeyer, Walter Fiedler, Franziska Modemann, Susanne Ghandili
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  • Acute Spontaneous Colonic Perforation in a Case of Newly Confirmed Scleroderma: Case Report
    Glenn Goodwin, Christian Ryckeley, Davide Fox, Michael Ashley, Laurence Dubensky, Mauricio Danckers, Todd Slesinger
    Interactive Journal of Medical Research.2023; 12: e43295.     CrossRef
  • Surgical outcomes and prognostic factors associated with emergency left colonic surgery
    Dauda Bawa, Yasser Mohammad Khalifa, Saleem Khan, Waddah Norah, Nibras Noman
    Annals of Saudi Medicine.2023; 43(2): 97.     CrossRef
  • Fatal Case of Perforated Cytomegalovirus Colitis: Case Report and Systematic Review
    Andrea T. Fisher, Kovi E. Bessoff, Veronica Nicholas, James Badger, Lisa Knowlton, Joseph D. Forrester
    Surgical Infections.2022; 23(2): 127.     CrossRef
  • An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation
    Jing Chen, Julia S. Caserto, Ida Ang, Kaavian Shariati, James Webb, Bo Wang, Xi Wang, Nikolaos Bouklas, Minglin Ma
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  • Predictors of mortality in patients with acute small-bowel perforation transferred to ICU after emergency surgery: a single-centre retrospective cohort study
    Jianzhang Wu, Ping Shu, Hongyong He, Haojie Li, Zhaoqing Tang, Yihong Sun, Fenglin Liu
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    Tareq Swedan, Mohamed Morjan, Mulham Jarjanazi, Nafiza Martini, Alaa Aldin Ismail, Hebatullah Awad, Shamseh Benbash
    Journal of Pediatric Surgery Case Reports.2022; 81: 102276.     CrossRef
  • The Clinical Significance of Shock Index and GFR in the Differential Diagnosis of Perforated Appendicitis
    Ferhat ÇAY, Ali DURAN
    Journal of Contemporary Medicine.2022; 12(4): 504.     CrossRef
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    Seung-Young Oh, Hannah Lee, Ho Geol Ryu, Hyuk-Joon Lee
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    Reem Moala AlHazmi, Dunya Nasrallah Alfaraj, Shaykhah Nasser AlNaimi, Sarah Mohammed AlQahtani, Mashael Hamed AlJuwayed, Hazem Mohammed Zakriea, Mohammed S Foula
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    Luis R. M. Nadal, Artur M. A. da Silva, Larissa Johann, Shuaib H. El Boustani, Maria Beatriz A. S. Medrado, Jose F. M. Farah, Renato A. Lupinacci
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  • Prognostic Factors and Management for Left Colonic Perforation: Can Hartmann’s Procedure Be Preventable?
    Yilseok Joo, Yujin Lee, Taeyoung Yoo, Jungbin Kim, Inseok Park, Geumhee Gwak, Hyunjin Cho, Keunho Yang, Kiwhan Kim, Byung-Noe Bae
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    Byung Soh Min
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Prompt Management Is Most Important for Colonic Perforation After Colonoscopy
Hyun-Ho Kim, Bong-Hyeon Kye, Hyung-Jin Kim, Hyeon-Min Cho
Ann Coloproctol. 2014;30(5):228-231.   Published online October 28, 2014
DOI: https://doi.org/10.3393/ac.2014.30.5.228
  • 7,102 View
  • 78 Download
  • 17 Web of Science
  • 14 Citations
AbstractAbstract PDF
Purpose

The incidence of complications after colonoscopy is very low. The complications after colonoscopy that are of clinical concern are bleeding and perforation. The present study was conducted to determine the clinical outcomes and the risk factors of a colostomy or a colectomy after colonoscopic colon perforation.

Methods

From March 2009 to December 2012, the records of all patients who were treated for colorectal perforation after colonoscopy were reviewed retrospectively. The following parameters were evaluated: age, sex, purpose of colonoscopy, management of the colonic perforation, and interval from colonoscopy to the diagnosis of a colonic perforation. A retrospective analysis was performed to determine the risk factors associated with major surgery for the treatment of a colon perforation after colonoscopy.

Results

A total 27 patients were included in the present study. The mean age was 62 years, and 16 were males. The purpose of colonoscopy was diagnostic in 18 patients. The most common perforation site was the sigmoid colon. Colonic perforation was diagnosed during colonoscopy in 14 patients, just after colonoscopy in 5 patients, and 24 hours or more after colonoscopy in 8 patients. For the treatment of colonic perforation, endoscopic clipping was performed in 3 patients, primary closure in 15 patients, colon resection in 2 patients, Hartmann's procedures in 4 patients, and diverting colostomy in 3 patients. If the diagnosis of perforation after colonoscopy was delayed for more than 24 hours, the need for major treatment was increased significantly.

Conclusion

Although a colonic perforation after colonoscopy is rare, if the morbidity and the mortality associated with the colonic perforation are to be reduced, prompt diagnosis and management are very important.

Citations

Citations to this article as recorded by  
  • Iatrogenic colon perforation during colonoscopy, diagnosis/treatment, and follow-up processes: A single-center experience
    Nihat Gülaydın, Raim İliaz, Atakan Özkan, A Hande Gökçe, Hanifi Önalan, Berrin Önalan, Aziz Arı
    Turkish Journal of Surgery.2022; 38(3): 221.     CrossRef
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    Vanessa L. Woolhead, Jacqueline C. Whittemore, Sarah A. Stewart
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    Liang Li, Bing Xue, Chunxia Yang, Zhongbo Han, Hongqiang Xie, Meng Wang
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    Carolyn R. Chew, Justin M. C. Yeung, Ian G. Faragher
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    Jose Luis Ulla-Rocha, Angel Salgado, Raquel Sardina, Raquel Souto, Raquel Sanchez-Santos, Juan Turnes
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    Zehui Wu, Huaping Xu, Yisheng Zhang, Lianghui Shi
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Case Reports
Transanal Evisceration Caused by Rectal Laceration
Aleix Martínez Pérez, María Teresa Torres Sánchez, Jose Manuel Richart Aznar, Eva María Martí Martínez, Manuel Martínez-Abad
Ann Coloproctol. 2014;30(1):47-49.   Published online February 28, 2014
DOI: https://doi.org/10.3393/ac.2014.30.1.47
  • 15,346 View
  • 52 Download
  • 3 Web of Science
  • 3 Citations
AbstractAbstract PDF

Transrectal evisceration caused by colorectal injury is an unusual entity. This pathology is more frequent in elderly patients and it is usually produced spontaneously. Rectal prolapse is the principal predisposing factor. An 81-year-old woman was taken to the hospital presenting exit of intestinal loops through the anus. After first reanimation measures, an urgent surgery was indicated. We observed the absence of almost every small intestine loop in the abdominal cavity; these had been moved to the pelvis. After doing the reduction, a 3 to 4 cm linear craniocaudal perforation in upper rectum was objectified, and Hartmann's procedure was performed. We investigated and knew that she frequently manipulate herself to extract her faeces. The fast preoperative management avoided a fatal conclusion or an extensive intestinal resection. Reasons that make us consider rectal self-injury as the etiologic factor are explained.

Citations

Citations to this article as recorded by  
  • Transanal evisceration of small bowel in two patients with chronic rectal prolapse: case presentation and literature review
    S Hajiev, A Ezzat, V Sivarajah, G Reese, N El-Masry
    The Annals of The Royal College of Surgeons of England.2021; 103(1): e29.     CrossRef
  • Evisceración de asas intestinales a través de periné posterior por traumatismo en paciente anciano
    Ana Alicia Tejera Hernández, David Fernández San Millan, Carlos David Trujillo Flores, Juan Ramón Hernández Hernández
    Revista Española de Geriatría y Gerontología.2016; 51(1): 58.     CrossRef
  • Transanal Evisceration of Small Bowel about One Case at the University Hospital Yalgado Ouédraogo of Ouagadougou
    Adama Sanou, Moussa Bazongo, Edgar Ouangré, Maurice Zida, Gilbert Patindé Bonkoungou, Rodrique Namékinsba Doamba, Sylvain Wendmi Karfo, Elie Yamba Sawadogo, Nayi Zongo, Si Simon Traoré
    Surgical Science.2016; 07(07): 291.     CrossRef
Rectal Perforation Caused by Anal Stricture After Hemorrhoid Treatment
Yong Joon Suh, Heon-Kyun Ha, Heung-Kwon Oh, Rumi Shin, Seung-Yong Jeong, Kyu Joo Park
Ann Coloproctol. 2013;29(1):28-30.   Published online February 28, 2013
DOI: https://doi.org/10.3393/ac.2013.29.1.28
  • 4,069 View
  • 38 Download
  • 1 Citations
AbstractAbstract PDF

Inappropriate therapies for hemorrhoids can lead to various complications including anorectal stricture. We report a patient presenting with catastrophic rectal perforation due to severe anal stricture after inappropriate hemorrhoid treatment. A 67-years old man with perianal pain visited the emergency room. The hemorrhoids accompanied by constipation, had tortured him since his youth. Thus he had undergone injection sclerotherapy several times by an unlicensed therapist and hemorrhoidectomy twice at the clinics of private practitioners. His body temperature was as high as 38.5℃. The computed tomographic scan showed a focal perforation of posterior rectal wall. The emergency operation was performed. The fibrotic tissues of the anal canal were excised. And then a sigmoid loop colostomy was constructed. The patient was discharged four days following the operation. This report calls attention to the enormous risk of unlicensed injection sclerotherapy and overzealous hemorrhoidectomy resulting in scarring, progressive stricture, and eventual rectal perforation.

Citations

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  • Laser hemorrhoidoplasty for hemorrhoidal disease: a systematic review and meta-analysis
    Hendry Lie, Evelyn Franca Caesarini, Antonius Agung Purnama, Andry Irawan, Taufik Sudirman, Wifanto Saditya Jeo, Bernardus Parish Budiono, Erik Prabowo, M. Iqbal Rivai, Ryanto Karobuana Sitepu
    Lasers in Medical Science.2022; 37(9): 3621.     CrossRef
Ischemic Pseudomembranous Colitis with Perforation due to Polyarteritis Nodosa.
Kim, Ki Nam
J Korean Soc Coloproctol. 2004;20(3):176-179.
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AbstractAbstract PDF
Polyarteritis nodosa, one of the necrotizing vasculitis involving predominantly small and medium sized arteries is a rare disease. Gastrointestinal involvements have been reported in more than 50% of patients at some time during its course. The small bowel is the frequent site of involvement in clinically apparent ischemic disease. The colon is less commonly involved, particularly at the initial presentation. We report a rare case of polyarteritis nodosa with ischemic colitis, perforation, and pseudomembrane formation.
The Conservative Treatment of Rectal Perforation after Insertion of A Stent and Chemo-Radiotherephy in the Patient with Obstructive Rectal Cancer.
Jung, Jai Hun , Kim, Seog Mo , Kim, Cheong Yong , Ko, Kang Seog
J Korean Soc Coloproctol. 2000;16(1):41-46.
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  • 13 Download
AbstractAbstract PDF
The use of self-expanding metal stent has been widely reported that its utility can make a palliative decompression treatment and one stage operation without doing colostomy in the patient with unresectable and resectable obstructive colorectal cancer, respectively. It, however, can sometimes cause complications such as intestinal perforation. We report that the conservative treantment could be possible without removing stent or performing laparotomy in case of intestinal perforation during chemoradiotheraphy after insert of stent for relieving colonic obstruction in the 53 years old female patient with stage IV rectal cancer.
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