KSCP
APFCP
SIUCP-ETS
Search
- Page Path
- HOME > Search
- Clinical Usefulness of Preoperative and Postoperative Chest Computed Tomography for Colorectal Cancer
- Jeong Hui Lee, Byung Kyu Ahn, Young Soo Nam, Kang Hong Lee
- J Korean Soc Coloproctol. 2010;26(5):359-364. Published online October 31, 2010
- DOI: https://doi.org/10.3393/jksc.2010.26.5.359
- 3,441 View
- 24 Download
- 2 Citations
-
Abstract
PDF Purpose This research sought to identify the utility value of chest computed tomography (CT) when it comes to the diagnosis of lung metastasis in cases of colorectal cancer.
Methods From September 2004 to January 2008, 266 patients who were treated for colorectal cancer at Department of Surgery, Hanyang University College of Medicine, were divided into two groups: one that underwent preoperative and postoperative periodical chest CT (periodical inspection group, PIG; May 2006 to January 2008, 135 patients) and one that did not undergo periodical chest CT (non-periodical inspection group, NPIG; September 2004 to April 2006, 131 patients) for comparison.
Results The overall lung metastasis diagnosis rates did not manifest any significant difference. The times to diagnose lung metastasis patients were 6.3 months and 15.7 months for the PIG and the NPIG, respectively (P = 0.022). The size of the metastatic lung nodule was smaller in the PIG than in the NPIG (< 1 cm in 9/9 patients vs. < 1 cm in 6/9 patients in the PIG and the NPIG, respectively; P = 0.02). A solitary lung metastasis was more frequently found in the PIG (5/9 patients) than in the NPIG (1/11 patients) (P = 0.024). During the follow-up period, 100% (2/2 patients) and 60% (3/5 patients) of the patients in the PIG and the NPIG, respectively, with stage III cancer underwent a lung metastasectomy (P = 0.002).
Conclusion Chest CT enables early diagnosis with a smaller size and a lower number of lung metastases in patients with colorectal cancer. Moreover, pulmonary the rate of the pulmonary resection for selected patients may be improved. However, the contribution of chest CT to increasing the survival rate must be investigated in a prospective randomized study.
-
Citations
Citations to this article as recorded by
- Development and validation of an artificial intelligence prediction model and a survival risk stratification for lung metastasis in colorectal cancer from highly imbalanced data: A multicenter retrospective study
Weiyuan Zhang, Xu Guan, Shuai Jiao, Guiyu Wang, Xishan Wang
European Journal of Surgical Oncology.2023; 49(12): 107107. CrossRef - CT Morphological Features Integrated With Whole-Lesion Histogram Parameters to Predict Lung Metastasis for Colorectal Cancer Patients With Pulmonary Nodules
TingDan Hu, ShengPing Wang, Xiangyu E, Ye Yuan, Lv Huang, JiaZhou Wang, DeBing Shi, Yuan Li, WeiJun Peng, Tong Tong
Frontiers in Oncology.2019;[Epub] CrossRef
- Development and validation of an artificial intelligence prediction model and a survival risk stratification for lung metastasis in colorectal cancer from highly imbalanced data: A multicenter retrospective study
- Surgical Resection for Lung Metastases from Colorectal Cancer
- Hyung Jin Kim, Bong-Hyeon Kye, Jae Im Lee, Sang Chul Lee, Yoon Suk Lee, In Kyu Lee, Won Kyung Kang, Hyeon-Min Cho, Seok Whan Moon, Seong Taek Oh
- J Korean Soc Coloproctol. 2010;26(5):354-358. Published online October 31, 2010
- DOI: https://doi.org/10.3393/jksc.2010.26.5.354
- 4,054 View
- 35 Download
- 7 Citations
-
Abstract
PDF
Purpose The lung is the second most common site of metastasis from colorectal cancer. Of all patients who undergo a curative resection for colorectal cancer, 10% to 15% will develop lung metastasis. As a hepatic resection of colorectal liver metastases results in improved survival, many reports have suggested that a pulmonary resection of a colorectal lung metastasis would also improve survival. The aim of this study was to analyze the postoperative outcomes of and the prognostic factors for a surgical resection of a lung metastasis.
Methods Between August 1997 and March 2006, 27 patients underwent surgical resections for colorectal lung metastases at Seoul St. Mary's hospital. A retrospective review of patients' characteristics and various tumor factors was performed.
Results The mean interval between colorectal resection and lung metastasis was 24.0 ± 15.1 months. The overall 3- and 5-year survival rates were 76.5% and 22.2%, respectively. The mean follow-up after pulmonary resection was 39.5 ± 21.6 months (range, 3.3 to 115 months). Except for the existence of hilar-lymph-node metastasis (P < 0.001), no risk factors that we studied were statistically significant. Two patients had hilar-lymph-node metastasis. They survived for only for 3.3- and 11.6-months, respectively.
Conclusion In our study, we found that a pulmonary resection for metastases from colorectal cancer may improve survival in selected patients.
-
Citations
Citations to this article as recorded by- Prognostic factors of para-aortic lymph node metastasis from colorectal cancer in highly selected patients undergoing para-aortic lymph node dissection
Shin Emoto, Yosuke Fukunaga, Manabu Takamatsu, Hiroshi Kawachi, Shuhei Sano, Tetsuro Tominaga, Toshiki Mukai, Tomohiro Yamaguchi, Toshiya Nagasaki, Takashi Akiyoshi, Tsuyoshi Konishi, Satoshi Nagayama, Masashi Ueno
Surgery Today.2024; 54(4): 356. CrossRef - The Determinants of Long-Term Outcomes After Colorectal Cancer Surgery: A Literature Review
Olorungbami K Anifalaje, Charles Ojo, Oluwaseyi T Balogun, Fikayo A Ayodele, Abeeb Azeez, Shirley Gabriels
Cureus.2024;[Epub] CrossRef - Distant Lung Recurrence of Rectal Cancer 20 Years After Primary Surgery
Sreekanthan Gobishangar, Sivakumaran Gobinath, Antony J Thanenthiran, Subramaniyam Bakeerathan
Cureus.2023;[Epub] CrossRef - Pulmonary metastasectomy with lymphadenectomy for colorectal pulmonary metastases: A systematic review
Martijn van Dorp, Jelle Egbert Bousema, Bart Torensma, Christian Dickhoff, Frank Jozef Christiaan van den Broek, Wilhelmina Hendrika Schreurs, Michel Gonzalez, Geert Kazemier, David Jonathan Heineman
European Journal of Surgical Oncology.2022; 48(1): 253. CrossRef - Safety and efficacy of combined resection of colorectal peritoneal and liver metastases
Stephanie Downs-Canner, Yongli Shuai, Lekshmi Ramalingam, James F. Pingpank, Matthew P. Holtzman, Herbert J. Zeh, David L. Bartlett, Haroon A. Choudry
Journal of Surgical Research.2017; 219: 194. CrossRef - CT-guided percutaneous laser ablation of metastatic lung cancer: three cases report and literature review
Qiyu Zhao, Guo Tian, Fen Chen, Liyun Zhong, Tian’an Jiang
Oncotarget.2017; 8(2): 2187. CrossRef - Simultaneous Laparoscopic Resection for Synchronous Pulmonary Metastases of Colorectal Cancers
Byung-Kwon Ahn
Gastroenterology & Hepatology: Open Access.2016;[Epub] CrossRef
- Prognostic factors of para-aortic lymph node metastasis from colorectal cancer in highly selected patients undergoing para-aortic lymph node dissection
- Pulmonary Metastases after Curative Resection in Patients with Colorectal Carcinomas.
- Park, In Ja , Kim, Hee Cheol , Lee, Gang Hong , Yu, Chang Sik , Kim, Tae Won , Chang, Heung Moon , Kim, Dong Kwan , Park, Seung Il , Kim, Jin Cheon
- J Korean Soc Coloproctol. 2003;19(5):307-313.
- 1,037 View
- 9 Download
-
Abstract
PDF
- PURPOSE
Pulmonary metastases from colorectal carcinomas have been reported to occur in 10% of all patients who undergo a curative resection. A number of studies have reported aggressive treatments, including lung resection, for pulmonary metastases that appear to prolong the survival in selected cases. The aim of this study was to assess the clinical characteristics, and the prognostic factors of pulmonary metastases, as well as the outcomes after resection of the pulmonary metastases.
METHODS
A retrospective study was performed on 104 patients who presented with primary pulmonary metastases without metastases in other organs after a curative resection for a colorectal carcinoma between January 1994 and December 2000 at Asan Medical Center. Pulmonary metastases were diagnosed by using serial changes in the chest X-ray and the CT. Univariate (log-rank) and multivariate (Cox's model) analyses were employed to identify the prognostic factors.
RESULTS
The mean interval between colorectal resection and pulmonary metastases (disease-free interval) was 22 (range: 4~64) months. Fifty-eight of 104 patients had pulmonary metastases originating from rectal cancer. More than half of the patients (55.7%) had bilateral multiple metastases. Fifty-six of 104 patients underwent chemotherapy, 28 conservative therapy, and 20 a pulmonary resection with the extent of the resection varying from a wedge resection of the metastatic nodule to a lobectomy. Prolonged survival was associated with serum CEA levels at the diagnosis of the metastases (P=0.02) and with the type of treatment (P<0.01).
CONCLUSIONS
The s-CEA level at the diagnosis of the pulmonary metastases appears to be a reliable predictor of survival in patients with pulmonary metastases from colorectal cancer. Resection of the pulmonary metastasis in colorectal cancer may significantly prolong survival. Thus, aggressive therapy, including surgery, should be considered for pulmonary metastatic tumors in selected groups.
- Pulmonary Resection for Lung Metastases from Colorectal Cancer.
- Choi, Hyo Seong , Youk, Eui Gon , Park, Young Jin , Park, Kyu Joo , Lee, Jae Woong , Kim, Joo Hyun , Park, Jae Gahb
- J Korean Soc Coloproctol. 1999;15(2):113-119.
- 1,168 View
- 1 Download
-
Abstract
PDF
- Isolated lung metastasis occurs in about 1% of all colorectal cancer cases. As in the case of isolated liver metastasis, resection of isolated lung metastasis results in 5 year survival rate of about 30%. PURPOSE: This study was performed to evaluate the survival benefit after pulmonary resection for metastatic colorectal cancer.
METHODS
Between January, 1992 and March, 1998, twelve patients underwent lung metastatectomy from colorectal cancer at the Seoul National University Hospital. We evaluated the clinical characteristics of patients and analyzed the follow-up results in 10 patients whose medical records were available. Indications for resection of pulmonary metastasis were complete resection of the primary tumor, no other organ involvement except lung, completely resectable lung lesion, and tolerable general condition of patient for lung resection.
RESULTS
Two patients had their primary tumors located in colon and 8 in rectum. Synchronous lung metastases were observed in 3 patients, and 7 patients had metachronous metastases developing 9 to 121 months (median; 33 months) after primary tumor resection. Eight patients had solitary metastatic nodule in lung, while two patients had multiple lesions confined to unilateral lung. Five patients underwent wedge resections, 4 underwent pulmonary lobectomies, and one patient had both wedge resection and lobectomy in unilateral lung. Three patients were lost during the follow-up, but remaining 7 patients are alive after median follow-up of period of 32 months and 6 of these patients have no postoperative recurrence. In addition, four of these 7 patients are alive for more than 3 years after lung metastatectomy.
CONCLUSION
Pulmonary metastasis from colorectal cancer without other organ involvement may be a candidate for lung resection. However, further studies are needed to determine the survival benefits after pulmonary resection.
First
Prev- Page of 1
- Next
- Last
TOP
