KSCP
APFCP
SIUCP-ETS
NSCRD
Search
- Page Path
- HOME > Search
Original Articles
Anorectal benign disease
- Long-term outcomes of intramural rectal botulinum toxin injections for urge fecal incontinence: a salvage therapy for sacral neuromodulation nonresponders?
- Philippe Onana Ndong, Véronique Vitton
- Ann Coloproctol. 2025;41(5):417-423. Published online October 23, 2025
- DOI: https://doi.org/10.3393/ac.2025.00332.0047
- 1,322 View
- 48 Download
-
Graphical Abstract
Abstract
PDF - Purpose
Sacral neuromodulation (SNM) failure in fecal incontinence (FI) management represents a therapeutic challenge, often leading to more invasive, less accepted alternatives with inconsistent efficacy. In this context, intramural rectal botulinum toxin A (BoNT-A) injection has recently emerged as a promising minimally invasive alternative for urge FI. This study aimed to evaluate the effectiveness of intramural rectal BoNT-A injections in the challenging subgroup of SNM nonresponders.
Methods
This retrospective, single-center study included patients with urge FI who underwent intramural rectal BoNT-A injections after SNM failure, between February 2018 and September 2024. The procedure involved endoscopic injection of 200 units of BoNT-A at 10 circumferential sites in the rectal wall. Treatment efficacy was assessed using the Cleveland Clinic Fecal Incontinence Score (CCFIS) and a visual analog scale (VAS) for symptom severity.
Results
Fifteen female patients met the inclusion criteria, with a median follow-up of 22.5 months (range, 4.4–103.2 months). Patients received a median of 2 injections, with a median reinjection interval of 9.8 months. CCFIS scores demonstrated significant improvement (median, 15 [range, 8–20] vs. 8 [range, 0–20]; P=0.001), as did VAS symptom scores (median, 4 [range, 0–5] vs. 2 [range, 0–5]; P=0.001). No adverse events were reported.
Conclusion
This study provides long-term evidence supporting intramural rectal BoNT-A injections as an effective option for managing urge FI, including as salvage therapy in SNM nonresponders. Further studies are necessary to confirm these findings and define the optimal role of BoNT-A within the therapeutic algorithm for urge FI.
Colorectal cancer
- Effects of clinical information on the treatment decisions for good responders to neoadjuvant chemoradiotherapy among rectal cancer patients
- Eon Bin Kim, In Ja Park, Hwa Jung Kim, Jong Keon Jang, Seong Ho Park, Young Il Kim, Min Hyun Kim, Jong Lyul Lee, Chan Wook Kim, Yong Sik Yoon, Seok-Byung Lim, Chang Sik Yu
- Ann Coloproctol. 2025;41(5):473-482. Published online July 10, 2025
- DOI: https://doi.org/10.3393/ac.2024.00276.0039
- 1,571 View
- 35 Download
- 1 Web of Science
- 1 Citations
-
Abstract
PDF
Supplementary Material - Purpose
The decision for treatment after neoadjuvant chemoradiotherapy (nCRT) in rectal cancer is intricately linked to tumor response and clinical parameters. This study was designed to elucidate determinants influencing treatment decisions for good responders to nCRT, while concurrently evaluating the ramifications of modifications in magnetic resonance imaging (MRI) tumor response evaluation protocols.
Methods
A survey was constructed with 5 cases of good responder after nCRT based on the magnetic resonance–based tumor regression grade (mrTRG) criteria. A total of 35 colorectal surgeons in Korea participated in the survey via email, and they were introduced to 2 discrete MRI-based tumor response evaluation methodologies: the conventional mrTRG and an emergent complete response (CR)/non-CR classification system. Surgeons were directed to select between total mesorectal excision, local excision, or a watch and wait strategy.
Results
Treatment decisions varied significantly (P<0.01), as gradually more clinical information was provided with mrTRG. The paradigm shift from mrTRG to CR/non-CR evaluation criterion instigated the highest alteration in decision (P<0.01). Even comparing with other sets of information, decision change with different tumor response assessment (i.e., mrTRG vs. CR/non-CR) was statistically significant (P<0.01). Three particular cases consistently displayed a declining predilection for total mesorectal excision, favoring a more pronounced inclination towards watch and wait strategy or local excision. Nonetheless, the magnitude of these decisional shifts oscillated depending on the specific endoscopic imagery present.
Conclusion
Our current findings underscore the significant role of tumor response assessment methods in shaping treatment decisions for rectal cancer patients who respond well to nCRT. This highlights the need for clear and accurate tools to interpret MRI results. -
Citations
Citations to this article as recorded by
- Clinical implications of radiologic criteria and prognostic factors for lateral lymph node metastasis in low rectal cancer
Gyung Mo Son
Annals of Coloproctology.2025; 41(6): 489. CrossRef
- Clinical implications of radiologic criteria and prognostic factors for lateral lymph node metastasis in low rectal cancer
ERAS
- The efficacy of mosapride on recovery of intestinal motility after elective colorectal cancer surgery: a randomized controlled trial
- Tharin Thampongsa, Bensita Saengsawang, Chairat Supsamutchai, Chumpon Wilasrusmee, Jakrapan Jirasiritham, Puvee Punmeechao, Visarat Palitnonkiat, Napaphat Poprom, Pattawia Choikrua, Pongsasit Singhathas
- Ann Coloproctol. 2025;41(3):232-238. Published online June 25, 2025
- DOI: https://doi.org/10.3393/ac.2024.00892.0127
- 7,069 View
- 1,061 Download
-
Abstract
PDFSupplementary Material
- Purpose
Postoperative ileus is the physiologic hypomotility of the gastrointestinal tract that occurs immediately after abdominal surgery. Mosapride citrate is known to enhance gastrointestinal motility. This study aimed to evaluate mosapride’s impact on postoperative ileus and gastrointestinal motility in patients undergoing elective colorectal surgery.
Methods
Forty-four patients with colorectal cancer undergoing surgery at Ramathibodi Hospital between July 2021 and August 2022 were randomly assigned to either a mosapride group or a control group. The mosapride group received 5 mg of mosapride via the enteric route with 50 mL of water 3 times daily, beginning on postoperative day 1, while the control group received 5 mg of a placebo with 50 mL of water on the same schedule. A single investigator, blinded to the treatment assignments in this triple-blind study, evaluated the postoperative time to the first bowel movement and passage of flatus. Secondary outcomes included the time to step diet, length of postoperative hospital stay, and adverse effects.
Results
There were 23 patients in the control group and 21 in the mosapride group. There were no significant differences in baseline patient characteristics between the 2 groups. The mosapride group demonstrated significantly shorter times to the first bowel movement (26 hours vs. 50 hours, P=0.004) and passage of flatus (40 hours vs. 70 hours, P=0.003).
Conclusion
Mosapride significantly improved the recovery of gastrointestinal motility and reduced the length of hospital stay without causing any serious adverse effects in patients undergoing elective colorectal surgery. Trial registration: ClinicalTrials.gov identifier: NCT04905147
Minimally invasive surgery
- Impact of single-port laparoscopic approach on scar assessment by patients and observers: a multicenter retrospective study
- Sung Uk Bae, Kyeong Eui Kim, Chang-Woo Kim, Ji-Hoon Kim, Woon Kyung Jeong, Yoon-Suk Lee, Seong Kyu Baek, Suk-Hwan Lee, Jun-Gi Kim
- Ann Coloproctol. 2025;41(2):154-161. Published online April 29, 2025
- DOI: https://doi.org/10.3393/ac.2024.00563.0080
- 4,435 View
- 80 Download
- 1 Citations
-
Abstract
PDF
- Purpose
This study aimed to compare the wound cosmesis of a single-incision approach on scar assessment after laparoscopic surgery for colon cancer.
Methods
This study included 32 patients undergoing single-port laparoscopic surgery (SPLS) and 61 patients undergoing multiport laparoscopic surgery (MPLS) for colon cancer at 3 tertiary referral hospitals between September 2011 and December 2019. We modified and applied the Korean version of the Patient and Observer Scar Assessment Scale (POSAS) to assess cosmetic outcomes. To assess the interobserver reliability using intraclass correlation coefficient values for the Observer Scar Assessment Scale (OSAS), the surgeons evaluated 5 images of postoperative scars.
Results
No significant differences were observed in the time before the return of normal bowel function, time to sips of water and soft diet initiation, length of in-hospital stay, and postoperative complication rate. The SPLS group had a shorter total incision length than the MPLS group. The POSAS favored the SPLS approach, revealing significant differences in the Patient Scar Assessment Scale (PSAS), OSAS, and overall scores. The SPLS approach was an independent factor influencing the POSAS, PSAS, and OSAS scores. Eleven colorectal surgeons had a significantly substantial intraclass coefficient.
Conclusion
The cosmetic outcomes of SPLS as assessed by the patients and surgeons were superior to those of MPLS in colon cancer. Reducing the number of ports is an independent factor affecting scar assessment by patients and observers. -
Citations
Citations to this article as recorded by- Investigating the Efficacy of Layered Moderate Tension Reduction Suturing in Facial Aesthetic Surgery
Gui H Wang, Jin Y Gang, Yan Li
Cureus.2025;[Epub] CrossRef
- Investigating the Efficacy of Layered Moderate Tension Reduction Suturing in Facial Aesthetic Surgery
ERAS
- Effect of continuous wound infiltration on patients using intravenous patient-controlled analgesia for pain management after reduced-port laparoscopic colorectal surgery
- Hyeon Deok Choi, Sung Uk Bae
- Ann Coloproctol. 2024;40(6):564-572. Published online November 22, 2024
- DOI: https://doi.org/10.3393/ac.2023.00143.0020
- 4,766 View
- 132 Download
- 1 Web of Science
- 1 Citations
-
Graphical Abstract
Abstract
PDF
- Purpose
Continuous wound infiltration (CWI) has been introduced as a component of multimodal analgesia to counteract the adverse effects of the most frequently used opioids. Advantages of reduced-port laparoscopic surgery (RPLS) include cosmetic benefits and decreased postoperative pain. We aimed to investigate the effect of CWI in patients using intravenous (IV) patient-controlled analgesia (PCA) for pain management after RPLS for colorectal cancer.
Methods
This retrospective study included 25 patients who received both CWI (0.5% ropivacaine infused over 72 hours) and IV PCA (fentanyl citrate) and 52 patients who received IV PCA alone. The primary endpoint was pain scores on postoperative days (PODs) 0, 1, and 2. Univariate and multivariate analyses were conducted to determine the factors affecting the pain score on POD 0.
Results
On POD 0, the mean numeric rating scale score was significantly lower in the CWI group than in the control group (3.2±0.8 vs. 3.7±0.9, P=0.042). However, the scores were comparable between the groups during the rest of the period. Within 24 hours of surgery, the CWI group consumed fewer opioids (0.7±0.9 vs. 1.3±1.1, P=0.018) and more nonsteroidal anti-inflammatory drugs (2.0±1.4 vs. 1.3±1.4, P=0.046) than the control group. Time to removal of IV PCA was significantly longer in the CWI group than in the control group (4.4±1.6 days vs. 3.4±1.0 days, P=0.016).
Conclusion
CWI with ropivacaine and IV PCA was more effective than IV PCA alone in controlling postoperative pain within 24 hours of surgery, and opioid use could be reduced further. -
Citations
Citations to this article as recorded by- Optimizing postoperative pain management in minimally invasive colorectal surgery
Soo Young Lee
Annals of Coloproctology.2024; 40(6): 525. CrossRef
- Optimizing postoperative pain management in minimally invasive colorectal surgery
Colorectal cancer
- Computed tomography–assessed presarcopenia and clinical outcomes after laparoscopic surgery for rectal cancer
- Ji Hyeong Song, Rak Kyun Oh, Jeong Eun Lee, Kyung Ha Lee, Ji Yeon Kim, Jin Soo Kim
- Ann Coloproctol. 2023;39(6):513-520. Published online December 12, 2023
- DOI: https://doi.org/10.3393/ac.2023.00031.0004
- 3,370 View
- 113 Download
- 2 Web of Science
- 2 Citations
-
Abstract
PDF
- Purpose
Previous studies have reported that presarcopenia negatively affects rectal cancer treatment. However, most studies have analyzed patients including majority of open surgery, and the association between presarcopenia and clinical outcomes after laparoscopic rectal cancer surgery remains unclear. This study aimed to evaluate the impact of presarcopenia on the clinical and oncological outcomes after laparoscopic rectal cancer surgery.
Methods
Three hundred and one patients undergoing laparoscopic rectal cancer surgery between December 2009 and May 2016 were enrolled. Body composition was assessed using computed tomography by measuring the muscle and fat areas at the third lumbar (L3) vertebra. The L3 skeletal muscle area was used to calculate the skeletal muscle index and evaluate presarcopenia.
Results
Presarcopenia was more common in older ( ≥ 70 years, P = 0.008) or female patients (P = 0.045). Patients with presarcopenia had decreased skeletal muscle area (P < 0.001), lower hemoglobin level (P = 0.034), longer time to first flatus (P < 0.001), and more frequent surgical site infection (P = 0.001). However, survival rates were not significantly different between those with and without presarcopenia.
Conclusion
Computed tomography-assessed presarcopenia was associated with delayed functional recovery and increased surgical site infection, although it was not revealed as a prognostic factor for oncological outcomes. -
Citations
Citations to this article as recorded by- Exploring potential predictors of low muscle mass and muscle loss in adults with cancer: A scoping review
Annie R. Curtis, Carla M. Prado, Liliana Orellana, Robin M. Daly, Judy Bauer, Linda Denehy, Lara Edbrooke, Brenton J. Baguley, Laura Alston, Nicholas Hardcastle, Jenelle Loeliger, Louise Moodie, Sharad Sharma, Nicole Kiss
Clinical Nutrition.2026; 56: 106531. CrossRef - Stress response, complications, and postoperative recovery in patients with hepatocellular carcinoma and comorbid anxiety/depression undergoing ultrasound-guided intervention
Shuang Xu, Liu-Wei Hao, Xia Li, Xiao-Ning Zhou
World Journal of Psychiatry.2025;[Epub] CrossRef
- Exploring potential predictors of low muscle mass and muscle loss in adults with cancer: A scoping review
Colorectal cancer
- International Society of University Colon and Rectal Surgeons survey of surgeons’ preference on rectal cancer treatment
- Audrius Dulskas, Philip F. Caushaj, Domas Grigoravicius, Liu Zheng, Richard Fortunato, Joseph W. Nunoo-Mensah, Narimantas E. Samalavicius
- Ann Coloproctol. 2023;39(4):307-314. Published online October 11, 2022
- DOI: https://doi.org/10.3393/ac.2022.00255.0036
- 7,067 View
- 137 Download
- 7 Web of Science
- 7 Citations
-
Graphical Abstract
Abstract
PDFSupplementary Material
- Purpose
Rectal cancer treatment has a wide range of possible approaches from radical extirpative surgery to nonoperative watchful waiting following chemoradiotherapy, with or without, additional chemotherapy. Our goal was to assess the personal opinion of active practicing surgeons on rectal cancer treatment if he/she was the patient.
Methods
A panel of the International Society of University Colon and Rectal Surgeons (ISUCRS) selected 10 questions that were included in a questionnaire that included other items including demographics. The questionnaire was distributed electronically to ISUCRS fellows and other surgeons included in our database and remained open from April 16 to 28, 2020.
Results
One hundred sixty-three specialists completed the survey. The majority of surgeons (n=65, 39.9%) chose the minimally invasive (laparoscopic) surgery for their personal treatment of rectal cancer. For low-lying rectal cancer T1 and T2, the treatment choice was standard chemoradiation+local excision (n=60, 36.8%) followed by local excision±chemoradiotherapy if needed (n=55, 33.7%). In regards to locally advanced low rectal cancer T3 or greater, the preference of the responders was for laparoscopic surgery (n=65, 39.9%). We found a statistically significant relationship between surgeons’ age and their preference for minimally invasive techniques demonstrating an age-based bias on senior surgeons’ inclination toward open approach.
Conclusion
Our survey reveals an age-based preference by surgeons for minimally invasive surgical techniques as well as organ-preserving techniques for personal treatment of treating rectal cancer. Only 1/4 of specialists do adhere to the international guidelines for treating early rectal cancer. -
Citations
Citations to this article as recorded by- Non-operative management of locally advanced rectal cancer with an emphasis on outcomes and quality of life: a narrative review
In Ja Park
Ewha Medical Journal.2025; 48(3): e40. CrossRef - Performance reporting design in artificial intelligence studies using image-based TNM staging and prognostic parameters in rectal cancer: a systematic review
Minsung Kim, Taeyong Park, Bo Young Oh, Min Jeong Kim, Bum-Joo Cho, Il Tae Son
Annals of Coloproctology.2024; 40(1): 13. CrossRef - Sex Disparities in Rectal Cancer Surgery: An In-Depth Analysis of Surgical Approaches and Outcomes
Chungyeop Lee, In Ja Park
The World Journal of Men's Health.2024; 42(2): 304. CrossRef - Effects of Adjuvant Chemotherapy on Oncologic Outcomes in Patients With Stage ⅡA Rectal Cancer Above the Peritoneal Reflection Who Did Not Undergo Preoperative Chemoradiotherapy
Hyo Seon Ryu, Jong Lyul Lee, Chan Wook Kim, Yong Sik Yoon, In Ja Park, Seok-Byung Lim, Yong Sang Hong, Tae Won Kim, Chang Sik Yu
Clinical Colorectal Cancer.2024; 23(4): 392. CrossRef - Comparative analysis of organ preservation attempt and radical surgery in clinical T2N0 mid to low rectal cancer
Hyeung-min Park, Jaram Lee, Soo Young Lee, Chang Hyun Kim, Hyeong Rok Kim
International Journal of Colorectal Disease.2024;[Epub] CrossRef - Beyond survival: a comprehensive review of quality of life in rectal cancer patients
Won Beom Jung
Annals of Coloproctology.2024; 40(6): 527. CrossRef - Unveiling the profound advantages of total neoadjuvant therapy in rectal cancer: a trailblazing exploration
Kyung Uk Jung, Hyung Ook Kim, Hungdai Kim, Donghyoun Lee, Chinock Cheong
Annals of Surgical Treatment and Research.2023; 105(6): 341. CrossRef
- Non-operative management of locally advanced rectal cancer with an emphasis on outcomes and quality of life: a narrative review
Review
Benign proctology
- A systematic review of translation and experimental studies on internal anal sphincter for fecal incontinence
- Minsung Kim, Bo-Young Oh, Ji-Seon Lee, Dogeon Yoon, Wook Chun, Il Tae Son
- Ann Coloproctol. 2022;38(3):183-196. Published online June 9, 2022
- DOI: https://doi.org/10.3393/ac.2022.00276.0039
- 7,033 View
- 157 Download
- 6 Web of Science
- 6 Citations
-
Abstract
PDF
- The complexity in the molecular mechanism of the internal anal sphincter (IAS) limits preclinical or clinical outcomes of fecal incontinence (FI) treatment. So far, there are no systematic reviews of IAS translation and experimental studies that have been reported. This systematic review aims to provide a comprehensive understanding of IAS critical role in FI. Previous studies revealed the key pathway for basal tone and relaxation of IAS in different properties as follows; calcium, Rho-associated, coiled-coil containing serine/threonine kinase, aging-associated IAS dysfunction, oxidative stress, renin-angiotensin-aldosterone, cyclooxygenase, and inhibitory neurotransmitters. Previous studies have reported improved functional outcomes of cellular treatment for regeneration of dysfunctional IAS, using various stem cells, but did not demonstrate the interrelationship between those results and basal tone or relaxation-related molecular pathway of IAS. Furthermore, these results have lower specificity for IAS-incontinence due to the included external anal sphincter or nerve injury regardless of the cell type. An acellular approach using bioengineered IAS showed a physiologic response of basal tone and relaxation response similar to human IAS. However, in both cellular and acellular approaches, the lack of human IAS data still hampers clinical application. Therefore, the IAS regeneration presents more challenges and warrants more advances.
-
Citations
Citations to this article as recorded by- A single-center retrospective analysis of endorectal advancement flaps used for the treatment of simple rectovaginal fistulas
Xuexiao Li, Wanjin Shao, Guidong Sun
Scandinavian Journal of Gastroenterology.2025; 60(4): 307. CrossRef - Anal sphincter reconstruction for fecal incontinence: Techniques, outcomes, and future directions
Hai-Liang Li, Hao-Ran Zhang, Yuan Wu, Kai-Qiang He, Tian-Jie Chen, Jing Wang
World Journal of Gastrointestinal Surgery.2025;[Epub] CrossRef - Tissue engineering and regenerative medicine approaches in colorectal surgery
Bigyan B. Mainali, James J. Yoo, Mitchell R. Ladd
Annals of Coloproctology.2024; 40(4): 336. CrossRef - 3D spheroids versus 2D-cultured human adipose stem cells to generate smooth muscle cells in an internal anal sphincter-targeting cryoinjured mouse model
Iltae Son, Minsung Kim, Ji-Seon Lee, Dogeon Yoon, You-Rin Kim, Ji Hye Park, Bo-Young Oh, Wook Chun, Sung-Bum Kang
Stem Cell Research & Therapy.2024;[Epub] CrossRef - Differentiation of Adipose-Derived Stem Cells into Smooth Muscle Cells in an Internal Anal Sphincter-Targeting Anal Incontinence Rat Model
Minsung Kim, Bo-Young Oh, Ji-Seon Lee, Dogeon Yoon, You-Rin Kim, Wook Chun, Jong Wan Kim, Il Tae Son
Journal of Clinical Medicine.2023; 12(4): 1632. CrossRef - Improving Efficiency and Accuracy in English Translation Learning: Investigating a Semantic Analysis Correction Algorithm
Lingmei Cao, Junru Fu
Applied Artificial Intelligence.2023;[Epub] CrossRef
- A single-center retrospective analysis of endorectal advancement flaps used for the treatment of simple rectovaginal fistulas
Original Articles
Colorectal cancer
- Short- and long-term outcomes of subtotal/total colectomy in the management of obstructive left colon cancer
- Jung Tak Son, Yong Bog Kim, Hyung Ook Kim, Chungki Min, Yongjun Park, Sung Ryol Lee, Kyung Uk Jung, Hungdai Kim
- Ann Coloproctol. 2023;39(3):260-266. Published online May 25, 2022
- DOI: https://doi.org/10.3393/ac.2022.00101.0014
- 8,412 View
- 194 Download
- 4 Web of Science
- 6 Citations
-
Abstract
PDF
- Purpose
Surgical management of obstructive left colon cancer (OLCC) is still a matter of debate. The classic Hartmann procedure (HP) has a disadvantage that requires a second major operation. Subtotal colectomy/total abdominal colectomy (STC/TC) with ileosigmoid or ileorectal anastomosis is proposed as an alternative procedure to avoid stoma and anastomotic leakage. However, doubts about morbidity and functional outcome and lack of long-term outcomes have made surgeons hesitate to perform this procedure. Therefore, this trial was designed to provide data for morbidity, functional outcomes, and long-term outcomes of STC/TC.
Methods
This study retrospectively analyzed consecutive cases of OLCC that were treated by STC/TC between January 2000 and November 2020 at a single tertiary referral center. Perioperative outcomes and long-term outcomes of STC/TC were analyzed.
Results
Twenty-five descending colon cancer (45.5%) and 30 sigmoid colon cancer cases (54.5%) were enrolled in this study. Postoperative complications occurred in 12 patients. The majority complication was postoperative ileus (10 of 12). Anastomotic leakage and perioperative mortality were not observed. At 6 to 12 weeks after the surgery, the median frequency of defecation was twice per day (interquartile range, 1–3 times per day). Eight patients (14.5%) required medication during this period, but only 3 of 8 patients required medication after 1 year. The 3-year disease-free survival was 72.7% and 3-year overall survival was 86.7%.
Conclusion
The risk of anastomotic leakage is low after STC/TC. Functional and long-term outcomes are also acceptable. Therefore, STC/TC for OLCC is a safe, 1-stage procedure that does not require diverting stoma. -
Citations
Citations to this article as recorded by- Controversial issues of colon stenting in case of tumor obstructive intestinal obstruction: surgical and oncological aspects
S.A. Aliyev, E.S. Aliyev, T.K. Aliyev
Endoscopic Surgery.2025; 31(2): 65. CrossRef - The Safety of Primary Anastomosis Without Protective Stoma in Emergency Left Colon Surgery: A Meta-Analysis
Zhiyan Wang, Wentao Sheng, Senjie Dai, Xuanzhou Li, Guojian Lin, Xiaohong Kang
Journal of Investigative Surgery.2025;[Epub] CrossRef - Ileus After Colectomy in the Modern Era: A Population-Based Analysis
Grace M. Crouch, Samantha Hendren, Kara K. Brockhaus, Wenjing Weng, Jami L. Boyd, Cheryl Rocker, Robert K. Cleary
Diseases of the Colon & Rectum.2025; 68(8): 1001. CrossRef - Influence of the type of anatomic resection on anastomotic leak after surgery for colon cancer
Suat Chin Ng, Andrew McCombie, Frank Frizelle, Tim Eglinton
ANZ Journal of Surgery.2024; 94(3): 424. CrossRef - Complete Obstruction, a Real Risk Factor: A Comprehensive Study on Obstruction in Stage IIA Colon Cancer With Propensity Score Matching Analysis
Soo Young Oh, Chan Wook Kim, Seonok Kim, Min Hyun Kim, Young Il Kim, Jong Lyul Lee, Yong Sik Yoon, In Ja Park, Seok-Byung Lim, Chang Sik Yu
Clinical Colorectal Cancer.2024; 23(2): 135. CrossRef - Can we use colon stenting in accelerated recovery programs for surgical treatment colon cancer complicated by obstructive intestinal obstruction? A literature review
Saday A. Aliyev, Emil S. Aliyev
Russian Journal of Oncology.2024; 29(2): 130. CrossRef
- Controversial issues of colon stenting in case of tumor obstructive intestinal obstruction: surgical and oncological aspects
- Right-sided acute diverticulitis in the West: experience at a university hospital in Argentina
- René M. Palacios Huatuco, Diana A. Pantoja Pachajoa, Julian E. Liaño, Héctor A. Picón Molina, Rafael Palencia, Alejandro M. Doniquian, Matías Parodi
- Ann Coloproctol. 2023;39(2):123-130. Published online November 24, 2021
- DOI: https://doi.org/10.3393/ac.2021.00402.0057
- 8,210 View
- 162 Download
- 2 Web of Science
- 1 Citations
-
Abstract
PDF
- Purpose
In the West, diverticular disease is located mainly in the left colon. However, it can also present in the right colon, with an incidence of 1% to 2% in Caucasians. The purpose of this study was to describe our experience in right-sided acute diverticulitis (RD).
Methods
In this retrospective study, 410 patients with acute diverticulitis treated from 2013 to 2020 were included in a university hospital in Córdoba, Argentina. Colonic diverticulitis was stratified into 2 groups; RD and left-sided acute diverticulitis. Demographic and clinical variables, laboratory and imaging findings, type of treatment, follow-up, and recurrence were analyzed.
Results
Sixteen patients (3.9%) with RD were identified; 62.5% were male and the mean age was 40.7±11.7 years. A total of 81.3% were Caucasian and 18.7% Native American. Significant differences were found between both groups of diverticulitis; patients with RD were younger (P=0.001), with lower BMI (P=0.01), comorbidity rate (P=0.01), Charlson comorbidity index (P=0.02), hospital stay (P=0.01), severity according to the Hinchey classification (P=0.001) and had a lower recurrence rate (P=0.001). There were no significant differences in sex (P=0.95), duration of pain until admission (P=0.05), laboratory findings (P=0.23) and treatment (P=0.34).
Conclusion
Conservative treatment predominated in RD, with a lower rate of complications and recurrences, providing data that support conservative therapy as initial treatment in RD in our environment. -
Citations
Citations to this article as recorded by- Comparison of surgical management and outcomes of acute right
colic and sigmoid diverticulitis: a French national retrospective cohort study
E. Karam, C. Sabbagh, L. Beyer-Bergeot, P. Zerbib, V. Bridoux, G. Manceau, Y. Panis, E. Buscail, A. Venara, I. Khaoudy, M. Gaillard, M. Viennet, A. Thobie, B. Menahem, C. Eveno, C. Bonnel, J.-Y. Mabrut, B. Badic, C. Godet, Y. Eid, E. Duchalais, Z. Lakkis,
Techniques in Coloproctology.2024;[Epub] CrossRef
- Comparison of surgical management and outcomes of acute right
colic and sigmoid diverticulitis: a French national retrospective cohort study
- Comparison of long-term outcomes of colonic stenting as a “bridge to surgery” and emergency surgery in patients with left-sided malignant colonic obstruction
- Supakij Khomvilai, Sukit Pattarajierapan
- Ann Coloproctol. 2023;39(1):17-26. Published online July 29, 2021
- DOI: https://doi.org/10.3393/ac.2021.00227.0032
- 9,117 View
- 237 Download
- 8 Web of Science
- 8 Citations
-
Abstract
PDF
- Purpose
Long-term oncologic outcomes of colonic stenting as a “bridge to surgery” in patients with left-sided malignant colonic obstruction (LMCO) are unclear. This study was performed to compare long-term outcomes of self-expandable metal stent (SEMS) insertion as a bridge to surgery and emergency surgery in patients with acute LMCO.
Methods
This retrospective cohort study included patients with acute LMCO who underwent SEMS insertion as a bridge to surgery or emergency surgery. The primary outcomes were 5-year disease-free survival (DFS), overall survival (OS), and recurrence rate. Survival outcomes were determined using the Kaplan-Meier method and compared using log-rank tests.
Results
There was a trend of worsening 5-year OS rate in the SEMS group compared with emergency surgery group (45% vs. 57%, P=0.07). In stage-wise subgroup analyses, a trend of deteriorating 5-year OS rate in the SEMS group with stage III (43% vs. 59%, P=0.06) was observed. The 5-year DFS and recurrence rate were not different between groups. The overall median follow-up time was 58 months. On multivariate analysis, age of ≥65 years and American Joint Committee on Cancer stage of ≥III, and synchronous metastasis were significant poor prognostic factors for OS (hazard ratio [HR], 1.709; 95% confidence interval [CI], 1.007–2.900; P=0.05/HR, 1.988; 95% CI, 1.038–3.809; P=0.04/HR, 2.146; 95% CI, 1.191–3.866; P=0.01; respectively).
Conclusion
SEMS as a bridge to surgery may have adverse oncologic outcomes. Patients in the SEMS group had a trend of worsening 5-year OS rate without higher recurrence. -
Citations
Citations to this article as recorded by- Transforming outcomes: the pivotal role of self-expanding metal stents in right- and left-sided malignant colorectal obstructions-bridge to surgery: a comprehensive review and meta-analysis
Sheza Malik, Priyadarshini Loganathan, Hajra Khan, Abul Hasan Shadali, Pradeep Yarra, Saurabh Chandan, Babu P. Mohan, Douglas G. Adler, Shivangi Kothari
Clinical Endoscopy.2025; 58(2): 240. CrossRef - Controversial issues of colon stenting in case of tumor obstructive intestinal obstruction: surgical and oncological aspects
S.A. Aliyev, E.S. Aliyev, T.K. Aliyev
Endoscopic Surgery.2025; 31(2): 65. CrossRef - Primary tumor resection vs. self-expandable metallic stent in unresectable obstructive stage IV colorectal cancer: a comparative outcome study
Chang Hyun Kim, Jae Kyun Ju, Jaram Lee, Hyeung-min Park, Soo Young Lee, Hyeong Rok Kim, Young Eun Joo, Sung Bum Cho
Annals of Surgical Treatment and Research.2025; 109(2): 89. CrossRef - Complete Obstruction, a Real Risk Factor: A Comprehensive Study on Obstruction in Stage IIA Colon Cancer With Propensity Score Matching Analysis
Soo Young Oh, Chan Wook Kim, Seonok Kim, Min Hyun Kim, Young Il Kim, Jong Lyul Lee, Yong Sik Yoon, In Ja Park, Seok-Byung Lim, Chang Sik Yu
Clinical Colorectal Cancer.2024; 23(2): 135. CrossRef - Can we use colon stenting in accelerated recovery programs for surgical treatment colon cancer complicated by obstructive intestinal obstruction? A literature review
Saday A. Aliyev, Emil S. Aliyev
Russian Journal of Oncology.2024; 29(2): 130. CrossRef - Colonic stenting: is the bridge to surgery worth its cost? A cost-effectiveness analysis at a single Asian institution
Michelle Shi Qing Khoo, Frederick H. Koh, Sharmini Su Sivarajah, Leonard Ming-Li Ho, Darius Kang-Lie Aw, Cheryl Xi-Zi Chong, Fung Joon Foo, Winson Jianhong Tan
Annals of Coloproctology.2024; 40(6): 555. CrossRef - Comparison of colonic stenting and stoma creation as palliative treatment for incurable malignant colonic obstruction
Sukit Pattarajierapan, Chatiyaporn Manomayangoon, Panat Tipsuwannakul, Supakij Khomvilai
JGH Open.2022; 6(9): 630. CrossRef - Oncologic safety of colonic stenting as a bridge to surgery in left-sided malignant colonic obstruction: Current evidence and prospects
Sukit Pattarajierapan, Nattapanee Sukphol, Karuna Junmitsakul, Supakij Khomvilai
World Journal of Clinical Oncology.2022; 13(12): 943. CrossRef
- Transforming outcomes: the pivotal role of self-expanding metal stents in right- and left-sided malignant colorectal obstructions-bridge to surgery: a comprehensive review and meta-analysis
Malignant disease, Rectal cancer,Prognosis and adjuvant therapy,Minimally invasive surgery
- Should transanal total mesorectal excision be implemented in medium-sized colorectal unit? technical and oncological outcome
- Man-fung Ho, Dennis Chung-Kei Ng, Janet Fung-yee Lee, Simon Siu-man Ng
- Ann Coloproctol. 2022;38(3):207-215. Published online July 28, 2021
- DOI: https://doi.org/10.3393/ac.2020.00941.0134
- 5,718 View
- 160 Download
- 4 Web of Science
- 3 Citations
-
Abstract
PDF
- Purpose
This study was performed to evaluate the outcome of implementation of transanal total mesorectal excision (TaTME) for low rectal cancer in a regional hospital and in comparison to laparoscopic (Lap) TME.
Methods
Consecutive patients with low rectal cancer of which the lowest border of the tumour was located beween 1 and 5 cm from the puborectalis who underwent TME at North District Hospital between January 2013 and December 2019 were included. Clinical, operative, and pathologic outcomes were compared between Lap TME and TaTME. The primary end point was complication profile.
Results
Thirty-five patients underwent Lap TME and 45 patients underwent TaTME for low rectal cancer. The conversion rate of the TaTME group was significantly lower than that of the Lap TME group (4.4% vs. 20%, P=0.029), but the operating time was longer (259 minutes vs. 219 minutes, P=0.009). The tumour location was significantly lower in the TaTME group, but the distal resection margins were adequate and not different between both groups. The TaTME group had higher incidence rates of prolonged ileus and urinary tract infection, but the other complications were similar between the two groups. The resection margin positivity rates of the TaTME and Lap TME groups were 2.2% and 5.7%, respectively (P=0.670). At a median follow up of 39 months, no abnormal early recurrence was detected.
Conclusion
It is technically feasible and oncologically safe to perform TaTME in a medium-volume colorectal unit. Patients with difficult pelvic anatomy can benefit by reducing the risk of conversion and margin positivity rate. -
Citations
Citations to this article as recorded by- Transanal versus transabdominal total mesorectal excision for rectal cancer in minimally invasive surgery: meta-analysis
Chun-Kai Liao, Yen-Lin Yu, Ya-Ting Kuo, Yu-Jen Hsu, Yih-Jong Chern, Yueh-Chen Lin, Pao-Shiu Hsieh, Jeng-Fu You, Jy-Ming Chiang
BJS Open.2025;[Epub] CrossRef - Sex Disparities in Rectal Cancer Surgery: An In-Depth Analysis of Surgical Approaches and Outcomes
Chungyeop Lee, In Ja Park
The World Journal of Men's Health.2024; 42(2): 304. CrossRef - Do Laparoscopic Approaches Ensure Oncological Safety and Prognosis for Serosa-Exposed Colon Cancer? A Comparative Study against the Open Approach
Ji-Hyun Seo, In-Ja Park
Cancers.2023; 15(21): 5211. CrossRef
- Transanal versus transabdominal total mesorectal excision for rectal cancer in minimally invasive surgery: meta-analysis
Benign proctology
- Long-term outcomes after anal fistula surgery: results from two university hospitals in Thailand
- Weeraput Chadbunchachai, Varut Lohsiriwat, Krisada Paonariang
- Ann Coloproctol. 2022;38(2):133-140. Published online June 7, 2021
- DOI: https://doi.org/10.3393/ac.2021.01.06
- 13,580 View
- 223 Download
- 7 Web of Science
- 5 Citations
-
Abstract
PDF
- Purpose
This study aimed to evaluate long-term outcomes after anal fistula surgery from university hospitals in Thailand.
Methods
A prospectively collected database of patients with cryptoglandular anal fistula undergoing surgery from 2011 to 2017 in 2 university hospitals was reviewed. Outcomes were treatment failure (persistent or recurrent fistula), fecal continence status, and chronic postsurgical pain.
Results
This study included 247 patients; 178 (72.1%) with new anal fistula and 69 (27.9%) with recurrent fistula. One hundred twenty-one patients (49.0%) had complex fistula; 53 semi-horseshoe (21.5%), 41 high transsphincteric (16.6%), 24 horseshoe (9.7%), and 3 suprasphincteric (1.2%). Ligation of intersphincteric fistula tract (LIFT) was the most common operation performed (n=88, 35.6%) followed by fistulotomy (n=79, 32.0%). With a median follow-up of 23 months (interquartile range, 12–45 months), there were 18 persistent fistulas (7.3%) and 33 recurrent fistulae (13.4%)—accounting for 20.6% overall failure. All recurrence occurred within 24 months postoperatively. Complex fistula was the only significant predictor for recurrent fistula with a hazard ratio of 4.81 (95% confidence interval, 1.82–12.71). There was no significant difference in healing rates of complex fistulas among seton staged fistulotomy (85.0%), endorectal advancement flap (72.7%), and LIFT (65.9%) (P=0.239). Four patients (1.6%) experienced chronic postsurgical pain. Seventeen patients (6.9%) reported worse fecal continence.
Conclusion
Overall failure for anal fistula surgery was 20.6%. Complex fistula was the only predictor for recurrent fistula. At least 2-year period of follow-up is suggested for detecting recurrent diseases and assessing patient-reported outcomes such as chronic pain and continence status. -
Citations
Citations to this article as recorded by- The Clinical Utility of Anorectal Manometry: A Review of Current Practices
Eleanor Aubrey Belilos, Zoë Post, Sierra Anderson, Mark DeMeo
Gastro Hep Advances.2025; 4(2): 100562. CrossRef - Mucosal advancement flap versus ligation of the inter-sphincteric fistula tract for management of trans-sphincteric perianal fistulas in the elderly: a retrospective study
Tamer A. A. M. Habeeb, Massimo Chiaretti, Igor A. Kryvoruchko, Antonio Pesce, Aristotelis Kechagias, Abd Al-Kareem Elias, Abdelmonem A. M. Adam, Mohamed A. Gadallah, Saad Mohamed Ali Ahmed, Ahmed Khyrallh, Mohammed H. Alsayed, Esmail Tharwat Kamel Awad, M
International Journal of Colorectal Disease.2025;[Epub] CrossRef - Sphincter-preserving total fistulectomy: promising outcomes but questions remain
Semra Demirli Atici, Nurhilal KIZILTOPRAK, Yasemin Yildirim
Updates in Surgery.2025;[Epub] CrossRef - Exploring Health-Related Quality of Life in Patients with Anal Fistulas: A Comprehensive Study
Tudor Mateescu, Lazar Fulger, Durganjali Tummala, Aditya Nelluri, Manaswini Kakarla, Lavinia Stelea, Catalin Dumitru, George Noditi, Amadeus Dobrescu, Cristian Paleru, Ana-Olivia Toma
Life.2023; 13(10): 2008. CrossRef - Lower Fistula Recurrence with Pulling Seton: A Retrospective Cohort Study
Ahmad Izadpanah, Ali Reza Safarpour, Mohammad Rezazadehkermani, Ali Zahedian, Reza Barati-Boldaji
Shiraz E-Medical Journal.2022;[Epub] CrossRef
- The Clinical Utility of Anorectal Manometry: A Review of Current Practices
Benign proctology
- Proposal for a New Score: Hemorrhoidal Bleeding Score
- Nadia Fathallah, Hélène Beaussier, Gilles Chatellier, Jean Meyer, Marc Sapoval, Nadia Moussa, Vincent de Parades
- Ann Coloproctol. 2021;37(5):311-317. Published online September 18, 2020
- DOI: https://doi.org/10.3393/ac.2020.08.19
- 7,812 View
- 220 Download
- 8 Web of Science
- 13 Citations
-
Abstract
PDF
- Purpose
We conducted a prospective study to evaluate a new hemorrhoidal bleeding score (HBS).
Methods
All consecutive patients who had consulted between May 1, 2016 and June 30, 2017 for bleeding hemorrhoidal disease were prospectively assessed at a proctological department. The study was conducted in 2 stages. The first stage assessed the validity of the score on a prospective patient cohort. A second stage assessed the interobserver reproducibility of the score on another prospective cohort.
Results
One hundred consecutive patients were studied (57 males; mean age, 49.70 years). A positive association between HBS and surgery indication was found (P<0.001). A cut-off value of the score of 5 (≤5 vs. >5) separated patients from surgical to medical-instrumental treatment with a sensitivity and specificity of 75.00% and 81.25%, respectively. In the multivariate analysis, only HBS was significantly associated with the operative decision (odds ratio, 12.22). Prolapse was no longer significantly associated with the surgical indication. After a mean follow-up after treatment of 7 months, HBS improved statistically significantly (P<0.0001). For the reproducibility of the score, an additional 30 consecutive patients (13 males; mean age, 53.14 years) were enrolled with an excellent agreement between 2 proctologists (kappa=0.983).
Conclusion
HBS is sensitive, specific, and reproducible. It can assess the severity of hemorrhoidal bleeding. It can discriminate between the most severe surgery-indicated patients and does so in a more efficient way than the Goligher prolapse score. It also allows quantifying the extent of change in hemorrhoidal bleeding after treatment. -
Citations
Citations to this article as recorded by- Arterial Embolization for the Internal Hemorrhoids Management: A Systematic Review
Mohammad Hossein Golezar, Hamed Ghorani, Fakhroddin Alemi, Farzad Fayedeh, Maryam Yeganegi, Samaneh Toutounchian, Hanieh Amani, Hadi Rokni Yazdi
Health Science Reports.2026;[Epub] CrossRef - The efficacy of Aescin combined with MPFF for early control of bleeding from acute hemorrhoids, A randomized controlled trial
Suwan Sanmee, Witcha Vipudhamorn, Pawit Sutharat, Ekkarin Supatrakul
Asian Journal of Surgery.2025; 48(1): 193. CrossRef - Hemorrhoidal disease: what role can rectal artery embolization play?
Julien Panneau, Diane Mege, Mathieu Di Bisceglie, Julie Duclos, Idir Khati, Vincent Vidal, Gaetano Gallo, Farouk Tradi
Frontiers in Surgery.2025;[Epub] CrossRef - Artery Embolization in the Treatment of Refractory Internal Hemorrhoids
Layth Alkhani, Jessica Stewart, Osman Ahmed
Applied Radiology.2025; 1(1): 1. CrossRef - Hemorrhoidal disease: Epidemiological study and analysis of predictive factors for surgical management
Nadia Fathallah, Amine Alam, Anne L. Rentien, Giorgio La Greca, Joshua Co, Elise Pommaret, Amélie Barré, Stéphane Kegne, Hélène Beaussier, Lucas Spindler, Vincent de Parades
Journal of Visceral Surgery.2024; 161(3): 161. CrossRef - Pathologie hémorroïdaire : étude épidémiologique et analyse des facteurs de risque de chirurgie
Nadia Fathallah, Amine Alam, Anne-Laure Rentien, Giorgio La Greca, Joshua Co, Elise Pommaret, Amélie Barré, Stéphane Kegne, Hélène Beaussier, Lucas Spindler, Vincent de Parades
Journal de Chirurgie Viscérale.2024; 161(3): 177. CrossRef - Imaging for Hemorrhoidal Disease: Navigating Rectal Artery Embolization from Planning to Follow-up
Jonathan Lindquist, James Hart, Katherine Marchak, Eduardo Bent Robinson, Premal Trivedi
Seminars in Interventional Radiology.2024; 41(03): 263. CrossRef - Russian multicenter observational HDQ study on the validation of the questionnaire for hemorrhoidal disease
Yu. A. Shelygin, Yu. M. Stoyko, Ivan V. Kostarev, E. A. Zagriadskiǐ, A. M. Bogomazov, E. B. Golovko, Yu. V. Khomitskaya, B. B. Kvasnikov, O. Zh. Linnik
Koloproktologia.2024; 23(4): 101. CrossRef - Emborrhoid technique performed on a patient with portal hypertension and chronic hemorrhoidal bleeding as a salvage therapy
Filipa Alves e Sousa, Pedro Marinho Lopes, Inês Bolais Mónica, Ana Catarina Carvalho, Pedro Sousa
CVIR Endovascular.2022;[Epub] CrossRef - Emborrhoid: Rectal Artery Embolization for Hemorrhoid Disease
Julien Panneau, Diane Mege, Mathieu Di Biseglie, Julie Duclos, Paul Habert, Vincent Vidal, Farouk Tradi
Seminars in Interventional Radiology.2022; 39(02): 194. CrossRef - Rectal Artery Embolization for Hemorrhoidal Disease: Anatomy, Evaluation, and Treatment Techniques
Julien Panneau, Diane Mege, Mathieu Di Biseglie, Julie Duclos, Paul Habert, Axel Bartoli, Vincent Vidal, Farouk Tradi
RadioGraphics.2022; 42(6): 1829. CrossRef - Treatment of Hemorrhoid in Unusual
Condition-Pregnancy
Hyo Seon Ryu
The Ewha Medical Journal.2022;[Epub] CrossRef - Hemorrhoid embolization: A review of current evidences
Reza Talaie, Pooya Torkian, Arash Dooghaie Moghadam, Farouk Tradi, Vincent Vidal, Marc Sapoval, Jafar Golzarian
Diagnostic and Interventional Imaging.2021;[Epub] CrossRef
- Arterial Embolization for the Internal Hemorrhoids Management: A Systematic Review
Benign GI diease
- Routine Intraoperative Bacterial Culture May Be Needed in Complicated Appendicitis
- Jung Tack Son, Gue Chun Lee, Hyung Ook Kim, Taewoon Kim, Donghyoun Lee, Sung Ryol Lee, Kyung Uk Jung, Hungdai Kim, Ho-Kyung Chun
- Ann Coloproctol. 2020;36(3):155-162. Published online June 30, 2020
- DOI: https://doi.org/10.3393/ac.2019.11.04.1
- 6,866 View
- 130 Download
- 12 Web of Science
- 14 Citations
-
Abstract
PDF
- Purpose
Choosing the appropriate antibiotic is important for treatment of complicated appendicitis. However, increasing multidrug resistant bacteria have been a serious problem for successful treatment. This study was designed to identify bacteria isolated from patients with complicated appendicitis and reveal their susceptibilities for antibiotics and their relationship with patient clinical course.
Methods
This study included patients diagnosed with complicated appendicitis and examined the bacterial cultures and antimicrobial susceptibilities of the isolates. Data were retrospectively collected from medical records of Kangbuk Samsung Hospital from January 2008 to February 2018.
Results
The common bacterial species cultured in complicated appendicitis were as follows: Escherichia coli (n=113, 48.9%), Streptococcus spp. (n=29, 12.6%), Pseudomonas spp. (n=23, 10.0%), Bacteriodes spp. (n=22, 9.5%), Klebsiella (n=11, 4.8%), and Enterococcus spp. (n=8, 3.5%). In antibiotics susceptibility testing, the positive rate of extended-spectrum beta lactamase (ESBL) was 9.1% (21 of 231). The resistance rate to carbapenem was 1.7% (4 of 231), while that to vancomycin was 0.4% (1 of 231). E. coli was 16.8% ESBL positive (19 of 113) and had 22.1% and 19.5% resistance rates to cefotaxime and ceftazidime, respectively. Inappropriate empirical antibiotic treatment (IEAT) occurred in 55 cases (31.8%) and was significantly related with organ/space surgical site infection (SSI) (7 of 55, P=0.005).
Conclusion
The rate of antibiotic resistance organisms was high in community-acquired complicated appendicitis in Koreans. Additionally, IEAT in complicated appendicitis may lead to increased rates of SSI. Routine intraoperative culture in patients with complicated appendicitis may be an effective strategy for appropriate antibiotic regimen. -
Citations
Citations to this article as recorded by- Optimizing Antibiotic Management for Adult Patients Presenting with Acute Perforated Appendicitis: A Quality Improvement Study
Carlos Gallego-Navarro, Jason Beckermann, Maria E. Linnaus, Hayden J. Swartz, Shelby Stewart, Justin M. York, Ryan R. Gassner, Christopher A. Kasal, Annaliese G. Seidel, Corey J. Wachter, Kirstin J. Kooda, Jennifer R. Rich, Mark D. Sawyer
Surgical Infections.2025; 26(3): 143. CrossRef - A Prospective Analysis of the Burden of Multi-Drug-Resistant Pathogens in Acute Appendicitis and Their Implication for Clinical Management
Faruk Koca, Sara Fatima Faqar-Uz-Zaman, Claudia Reinheimer, Michael Hogardt, Volkhard A. J. Kempf, Paul Ziegler, Andreas A. Schnitzbauer, Armin Wiegering, Wolf Otto Bechstein, Patrizia Malkomes
Antibiotics.2025; 14(4): 378. CrossRef - Bacteriological Profile and Antimicrobial Resistance in Intraoperative Purulent Samples From Acute Appendicitis: A 3‐Year Retrospective Analysis
Quanwei Wang, Xiao Xu, Weiwei Ma, Chengcheng Huang, Liqing Cao, Yaru Zhang
ANZ Journal of Surgery.2025;[Epub] CrossRef - Culture-based bacterial evaluation of the appendix lumen and antibiotic susceptibility of acute appendicitis in Japan: A single-center retrospective analysis
Hiroe Kitahara, Yonfan Park, Kai Seharada, Masaki Yoshimura, Akira Horiuchi, Yukihiko Karasawa
Medicine.2024; 103(29): e39037. CrossRef - Do Cultures From Percutaneously Drained Intra-abdominal Abscesses Change Treatment? A Retrospective Review
Andrew C. Esposito, Yuqi Zhang, Nupur Nagarkatti, William D. Laird, Nathan A. Coppersmith, Vikram Reddy, Ira Leeds, Anne Mongiu, Walter Longo, Ritche M. Hao, Haddon Pantel
Diseases of the Colon & Rectum.2023; 66(3): 451. CrossRef - Bacterial pathogens in pediatric appendicitis: a comprehensive retrospective study
Julia Felber, Benedikt Gross, Arend Rahrisch, Eric Waltersbacher, Evelyn Trips, Percy Schröttner, Guido Fitze, Jurek Schultz
Frontiers in Cellular and Infection Microbiology.2023;[Epub] CrossRef - An Update on Acute Appendicitis in Lebanon: Insights From a Single-Center Retrospective Study
Nagham Bazzi, Samer Dbouk, Ahmad Rached, Sadek Jaber, Hala Bazzi, Manal Jrad, Mariam Bazzi
Cureus.2023;[Epub] CrossRef - Bacterial peritonitis in paediatric appendicitis; microbial epidemiology and antimicrobial management
Keir Bhaskar, Simon Clarke, Luke S. P. Moore, Stephen Hughes
Annals of Clinical Microbiology and Antimicrobials.2023;[Epub] CrossRef - Aerobic Intraoperative Abdominal Cavity Culture Modifies Antibiotic Therapy and Reduces the Risk of Surgical Site Infection in Complicated Appendicitis with Peritonitis
Víctor Manuel Quintero-Riaza, Romario Chancí-Drago, Natalia Guzmán-Arango, Pablo Posada-Moreno, Tatiana López-Sandoval, Isabel Cristina Ramírez-Sánchez, Johanna Marcela Vanegas-Munera
Journal of Gastrointestinal Surgery.2023; 27(11): 2563. CrossRef - Does the Covid-19 pandemic have an effect on wound culture in patients undergoing appendectomy? A Case Control Study
Hacı BOLAT, Tuğba AVAN MUTLU
Journal of Contemporary Medicine.2022; 12(2): 332. CrossRef - Are We Hitting the Target?
Julia Elrod, Fatima Yarmal, Christoph Mohr, Martin Dennebaum, Michael Boettcher, Deirdre Vincent, Konrad Reinshagen, Ingo Koenigs
Pediatric Infectious Disease Journal.2022; 41(6): 460. CrossRef - Is Routine Intra-operative Gram Stain, Culture, and Sensitivity during an Appendectomy is Effective in Decreasing the Rate of Post-operative Infective Complications?
Muqdad Fuad, Ahmed Modher, Mohammed Habash
Open Access Macedonian Journal of Medical Sciences.2022; 10(B): 868. CrossRef - Die Bedeutung mikrobiologischer Ergebnisse für die Therapie der komplizierten Appendizitis – eine monozentrische Fall-Kontroll-Studie
F-X. Anzinger, K. Rothe, S. Reischl, C. Stöss, A. Novotny, D. Wilhelm, H. Friess, P-A. Neumann
Die Chirurgie.2022; 93(10): 986. CrossRef - Implications of bacteriological study in complicated and uncomplicated acute appendicitis
Sorin Cimpean, Alberto Gonzalez Barranquero, Ion Surdeanu, Benjamin Cadiere, Guy-Bernard Cadiere
Annals of Coloproctology.2022;[Epub] CrossRef
- Optimizing Antibiotic Management for Adult Patients Presenting with Acute Perforated Appendicitis: A Quality Improvement Study
Benign GI diease, Inflammatory bowel disease
- Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease
- Joon Suk Moon, Jong Lyul Lee, Chang Sik Yu, Seok-Byung Lim, In Ja Park, Yong Sik Yoon, Chan Wook Kim, Suk-Kyun Yang, Byong Duk Ye, Sang Hyoung Park, Hassan Abdullah Alsaleem, Jin Cheon Kim
- Ann Coloproctol. 2020;36(4):243-248. Published online March 16, 2020
- DOI: https://doi.org/10.3393/ac.2019.10.16.1
- 5,884 View
- 123 Download
- 8 Web of Science
- 9 Citations
-
Abstract
PDF
- Purpose
Upper gastrointestinal (GI) tract involvement in Crohn disease (CD) is rare and effectiveness of surgical treatment is limited. The aim of this study was to evaluate characteristics and surgical outcomes of upper GI CD.
Methods
Medical records of 811 patients who underwent intestinal surgery for CD between January 2006 and December 2015 at a single institution were reviewed. Upper GI CD was defined by involvement of the stomach to the fourth portion of duodenum, with or without concomitant small/large bowel CD involvement according to a modification of the Montreal classification.
Results
We identified 24 patients (21 males, 3 females) who underwent surgery for upper GI CD. The mean age at diagnosis was 27 ± 12 years, the mean age at surgery was 33 ± 11 years, and the mean duration of CD was 73.6 ± 56.6 months. Fifteen patients (62.5%) had history of previous perianal surgery. Ten patients (41.7%) had duodenal or gastric stricture and 14 patients (58.3%) had penetrating fistula; patients with fistula were significantly more likely to develop complications (57.1% vs. 20.0%, P = 0.035). One patient with stricture had surgical recurrence. In seven patients with fistula, fistula was related to previous anastomosis. Patients with fistula had significantly longer hospital stays than those with stricture (16 days vs. 11 days, P = 0.01).
Conclusion
Upper GI CD is rare among CD types (2.96%). In patients with upper GI CD, penetrating fistula was associated with longer hospital stay and more complications. -
Citations
Citations to this article as recorded by- Definitions, diagnosis, management, and outcomes of upper gastrointestinal Crohn's disease: an international, expert RAND/UCLA appropriateness study
Nathaniel A Cohen, Dominik Bettenworth, Neta Sror, Raneem Khedraki, Qijun Yang, Maria T Abreu, Raja Atreya, Badr Al-Bawardy, Susan J Connor, Geert D'Haens, Iris Dotan, Axel Dignass, Sara El Ouali, Brian Feagan, Roger Feakins, Richard Gearry, Ilyssa O Gord
The Lancet Gastroenterology & Hepatology.2026;[Epub] CrossRef - Diagnosis and Management of Upper Gastrointestinal Involvement in Adult Patients With Crohn’s Disease: A Systematic Review
Nathaniel A. Cohen, Neta Sror, Maliha Naseer, Dominik Bettenworth, Cathy Lu, Raneem Khedraki, Maria T. Abreu, Raja Atreya, Badr Al-Bawardy, Susan J. Connor, Geert d’Haens, Iris Dotan, Axel Dignass, Sara El Ouali, Brian Feagan, Roger Feakins, Richard Gearr
Clinical Gastroenterology and Hepatology.2025;[Epub] CrossRef - Upper Gastrointestinal Crohn’s Disease: Shedding Light on the Obscure L4 Classification Meaning
Francesca Lusetti, Cristina Bezzio, Alice De Bernardi, Michele Puricelli, Gianpiero Manes, Simone Saibeni
Journal of Clinical Medicine.2025; 14(22): 8260. CrossRef - Update S2k-Guideline Helicobacter pylori and gastroduodenal ulcer disease of the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS)
Wolfgang Fischbach, Jan Bornschein, Jörg C. Hoffmann, Sibylle Koletzko, Alexander Link, Lukas Macke, Peter Malfertheiner, Kerstin Schütte, Dieter-Michael Selgrad, Sebastian Suerbaum, Christian Schulz
Zeitschrift für Gastroenterologie.2024; 62(02): 261. CrossRef - Aktualisierte S2k-Leitlinie Helicobacter
pylori und gastroduodenale Ulkuskrankheit der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) – Juli 2022 – AWMF-Registernummer: 021–001
Zeitschrift für Gastroenterologie.2023; 61(05): 544. CrossRef - A systematic review and meta‐analysis of prevalence and clinical features of upper gastrointestinal (UGI) tract Crohn's disease in adults compared to non‐UGI types
Babak Tamizifar, Peyman Adibi, Maryam Hadipour, Vahid Mohamadi
JGH Open.2023; 7(5): 325. CrossRef - Upper gastrointestinal tract involvement of Crohn disease: clinical implications in children and adolescents
Eun Sil Kim, Mi Jin Kim
Clinical and Experimental Pediatrics.2022; 65(1): 21. CrossRef - Profiling non-coding RNA levels with clinical classifiers in pediatric Crohn’s disease
Ranjit Pelia, Suresh Venkateswaran, Jason D. Matthews, Yael Haberman, David J. Cutler, Jeffrey S. Hyams, Lee A. Denson, Subra Kugathasan
BMC Medical Genomics.2021;[Epub] CrossRef - Surgical Treatment of Upper Gastrointestinal Tract Crohn Disease: A Long Way to Go to Identify the Optimal Method
Soo Yeun Park
Annals of Coloproctology.2020; 36(4): 207. CrossRef
- Definitions, diagnosis, management, and outcomes of upper gastrointestinal Crohn's disease: an international, expert RAND/UCLA appropriateness study
Benign proctology
- Propiverine Hydrochloride as a Treatment for Fecal Incontinence
- Yasue Irei, Shota Takano, Kazutaka Yamada
- Ann Coloproctol. 2020;36(2):88-93. Published online March 16, 2020
- DOI: https://doi.org/10.3393/ac.2019.09.30.2
- 5,612 View
- 140 Download
- 2 Web of Science
- 3 Citations
-
Abstract
PDF
- Purpose
Propiverine hydrochloride (PH) is widely used for the treatment of urinary incontinence (UI) due to bladder overactivity. Moreover, the comorbidity of UI with fecal incontinence (FI) is known to be due to the relationship of both to nervous system disorders and dysfunction or weakening of the pelvic floor muscles. The aim of this single-arm prospective study was to evaluate the therapeutic value of PH for FI.Methods: Patients (n = 24) who were diagnosed as having both FI and UI from April 2015 to November 2016 were included in the study and administered a dosage of 10–20 mg PH every day for 1 month. The primary endpoint was to create a reduction in the frequency of FI per week. An evaluation criterion of ≥50% reduction in frequency was determined as effective. The percentage of the patients who achieved the ≥50% endpoint (responders) was also calculated.Results: The frequency of FI per week was 6.0 ± 8.2 (0.25–30) at baseline and reduced to 1.6 ± 2.1 (0–7) at the posttherapeutic state (P = 0.005). A reduction of ≥50% was seen in 14 of the patients (58.3%).Conclusion: PH reduced the frequency of FI in patients with both FI and UI. This study introduces a possible therapeutic option for the pharmacological treatment of FI. -
Citations
Citations to this article as recorded by- The Japan Society of Coloproctology Practice Guidelines for Fecal Incontinence 2024 (Revised Second Edition)
Keiji Koda, Toshiki Mimura, Tetsuo Yamana, Mitsuru Ishizuka, Tomoko Takahashi, Shota Takano, Tatsuya Abe, Yuji Nishizawa, Hidetoshi Katsuno, Masami Sato, Kaoru Nishimura, Masahiro Yoshida, Kotaro Maeda
Journal of the Anus, Rectum and Colon.2026; 10(1): 64. CrossRef - A systematic review of translation and experimental studies on internal anal sphincter for fecal incontinence
Minsung Kim, Bo-Young Oh, Ji-Seon Lee, Dogeon Yoon, Wook Chun, Il Tae Son
Annals of Coloproctology.2022; 38(3): 183. CrossRef - Is It a Refractory Disease?- Fecal Incontinence; beyond
Medication
Chungyeop Lee, Jong Lyul Lee
The Ewha Medical Journal.2022;[Epub] CrossRef
- The Japan Society of Coloproctology Practice Guidelines for Fecal Incontinence 2024 (Revised Second Edition)
Benign GI diease, Inflammatory bowel disease
- Short-term Outcomes of Elective 2-Stage Restorative Proctocolectomy for Ulcerative Colitis in Korea: Does Laparoscopy Have Benefits?
- Jun Woo Bong, Yong Sik Yoon, Jong Lyul Lee, Chan Wook Kim, In Ja Park, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
- Ann Coloproctol. 2020;36(1):41-47. Published online February 29, 2020
- DOI: https://doi.org/10.3393/ac.2019.03.29
- 5,227 View
- 87 Download
- 4 Web of Science
- 3 Citations
-
Abstract
PDF
- Purpose
This study aimed to compare the short-term outcomes of the open and laparoscopic approaches to 2-stage restorative proctocolectomy (RPC) for Korean patients with ulcerative colitis (UC).
Methods
We retrospectively analyzed the medical records of 73 patients with UC who underwent elective RPC between 2009 and 2016. Patient characteristics, operative details, and postoperative complications within 30 days were compared between the open and laparoscopic groups.
Results
There were 26 cases (36%) in the laparoscopic group, which had a lower mean body mass index (P = 0.025), faster mean time to recovery of bowel function (P = 0.004), less intraoperative blood loss (P = 0.004), and less pain on the first and seventh postoperative days (P = 0.029 and P = 0.027, respectively) compared to open group. There were no deaths, and the overall complication rate was 43.8%. There was no between-group difference in the overall complication rate; however, postoperative ileus was more frequent in the open group (27.7% vs. 7.7%, P = 0.043). Current smoking (odds ratio [OR], 44.4; P = 0.003) and open surgery (OR, 5.4; P = 0.014) were the independent risk factors for postoperative complications after RPC.
Conclusion
Laparoscopic RPC was associated with acceptable morbidity and faster recovery than the open approach. The laparoscopic approach is a feasible and safe option for surgical treatment for UC in selective cases. -
Citations
Citations to this article as recorded by- Patient-reported Outcome Measures in Ileoanal Pouch Surgery: a Systematic Review
Zakary Ismail Warsop, Carlo Alberto Manzo, Natalie Yu, Bilal Yusuf, Christos Kontovounisios, Valerio Celentano
Journal of Crohn's and Colitis.2024; 18(3): 479. CrossRef - Creation of an institutional preoperative checklist to support clinical risk assessment in patients with ulcerative colitis (UC) considering ileoanal pouch surgery
Bruno Augusto Alves Martins, Amira Shamsiddinova, Manal Mubarak Alquaimi, Guy Worley, Phil Tozer, Kapil Sahnan, Zarah Perry-Woodford, Ailsa Hart, Naila Arebi, Manmeet Matharoo, Janindra Warusavitarne, Omar Faiz
Frontline Gastroenterology.2024; 15(3): 203. CrossRef - Benefits of Elective Laparoscopic 2-Stage Restorative Proctocolectomy for Ulcerative Colitis in Korea
Sun Min Park, Won-Kyung Kang
Annals of Coloproctology.2020; 36(1): 3. CrossRef
- Patient-reported Outcome Measures in Ileoanal Pouch Surgery: a Systematic Review
Review
- Reconsideration of the Safety of Laparoscopic Rectal Surgery for Cancer
- Gyung Mo Son, Bong-Hyeon Kye, Min Ki Kim, Jun-Gi Kim
- Ann Coloproctol. 2019;35(5):229-237. Published online October 31, 2019
- DOI: https://doi.org/10.3393/ac.2019.10.16
- 6,340 View
- 117 Download
- 6 Web of Science
- 6 Citations
-
Abstract
PDF
- The oncological outcomes of laparoscopic rectal cancer surgery were evaluated in recent multicenter randomized clinical trials (RCTs). The MRC-CLASSIC, COLOR II, and COREAN trials found no differences in local recurrence or diseasefree survival rate between laparoscopic and open surgery. However, the noninferiority of laparoscopic surgery with respect to open surgery for rectal cancer was not established on statistical analysis in the ACOSOG Z6051 and the ALaCaRT trials. Quality of total mesorectal excision (TME) is one of the most important prognostic factors. Incomplete TME had unfavorable oncologic outcomes compared to complete TME. Although TME quality can be clearly identified on pathologic evaluation, there is controversy regarding the acceptable range of oncologically safe TME for laparoscopic surgery. It is not certain whether near-complete TME has an unfavorable oncologic impact and whether laparoscopic surgery with near-complete TME is an oncological threat. Therefore, the surgical community will be interested in the long-term outcomes and meta-analyses of ongoing large-scale RCTs. Laparoscopic rectal cancer surgery has been steadily improving its safety for oncology surgery, which has been reported consistently in various multicenter RCTs. To improve surgical quality, colorectal surgeons should choose the most appropriate surgical technique, including laparoscopic surgery.
-
Citations
Citations to this article as recorded by- Why did we encounter a pCRM-positive specimen whose preoperative MRI indicates negative mesorectal fascia involvement in middle to low rectal cancer?
F. Sumiyama, M. Hamada, T. Kobayashi, Y. Matsumi, R. Inada, H. Kurokawa, Y. Uemura
Techniques in Coloproctology.2025;[Epub] CrossRef - Efficacy of laparoscopic radical resection of colorectal cancer in older patients and its effects on inflammatory factors
Zhen-Yu Min, Jie Zhou, Zhong-Wei Zhu, Zhen-Zhong Fa
World Journal of Gastrointestinal Surgery.2025;[Epub] CrossRef - Operative and Survival Outcomes of Robotic-Assisted Surgery for Colorectal Cancer in Elderly and Very Elderly Patients: A Study in a Tertiary Hospital in South Korea
Hugo Cuellar-Gomez, Siti Mayuha Rusli, María Esther Ocharan-Hernández, Tae-Hoon Lee, Guglielmo Niccolò Piozzi, Seon-Hahn Kim, Cruz Vargas-De-León, Yazhou He
Journal of Oncology.2022; 2022: 1. CrossRef - Evidenz in der minimal-invasiven onkologischen Chirurgie des Kolons und des Rektums
Carolin Kastner, Joachim Reibetanz, Christoph-Thomas Germer, Armin Wiegering
Der Chirurg.2021; 92(4): 334. CrossRef - The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience
Hyuk-Jun Chung, Jun-Gi Kim, Hyung-Jin Kim, Hyeon-Min Cho, Bong-Hyeon Kye
Biomedicines.2021; 9(11): 1720. CrossRef - Reoperative laparoscopic rectal surgery: Another potential tool for the expert’s toolbox
Marc D. Basson
The American Journal of Surgery.2020; 219(6): 894. CrossRef
- Why did we encounter a pCRM-positive specimen whose preoperative MRI indicates negative mesorectal fascia involvement in middle to low rectal cancer?
Original Articles
- Efficacy and Feasibility of Adding Induction Chemotherapy to Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer: A Phase II Clinical Trial
- Hamid Nasrolahi, Sepideh Mirzaei, Mohammad Mohammadianpanah, Ali Mohammad Bananzadeh, Maral Mokhtari, Mohammad Reza Sasani, Ahmad Mosalaei, Shapour Omidvari, Mansour Ansari, Niloofar Ahmadloo, Seyed Hasan Hamedi, Nezhat Khanjani
- Ann Coloproctol. 2019;35(5):242-248. Published online October 31, 2019
- DOI: https://doi.org/10.3393/ac.2018.09.06
- 6,652 View
- 93 Download
- 5 Web of Science
- 5 Citations
-
Abstract
PDF
- Purpose
Currently, neoadjuvant chemoradiation (CRT) followed by total mesorectal resection is considered the standard of care for treating locally advanced rectal cancer. This study aimed to investigate the efficacy and feasibility of adding induction chemotherapy to neoadjuvant CRT in locally advanced rectal cancer.
Methods
This phase-II clinical trial included 54 patients with newly diagnosed, locally advanced (clinical T3–4 and/or N1–2, M0) rectal cancer. All patients were treated with 3 cycles of preoperative chemotherapy using the XELOX (capecitabine + oxaliplatin) regimen before and after a concurrent standard long course of CRT (45–50.4 Gy) followed by standard radical surgery. Pathologic complete response (PCR) rate and toxicity were the primary and secondary endpoints, respectively.
Results
The study participants included 37 males and 17 females, with a median age of 59 years (range, 20–80 years). Twenty-nine patients (54%) had clinical stage-II disease, and 25 patients (46%) had clinical stage-III disease. Larger tumor size (P = 0.006) and distal rectal location (P = 0.009) showed lower PCR compared to smaller tumor size and upper rectal location. Pathologic examinations showed significant tumor regression (6.1 ± 2.7 cm vs. 1.9 ± 1.8 cm, P < 0.001) with 10 PCRs (18.5%) compared to before the intervention. The surgical margin was free of cancer in 52 patients (96.3%). Treatment-related toxicities were easily tolerated, and all patients completed their planned treatment without interruption. Grade III and IV toxicities were infrequent.
Conclusion
The addition of induction chemotherapy to neoadjuvant CRT is an effective and well-tolerated treatment approach in patients with rectal cancer. -
Citations
Citations to this article as recorded by- Nanomedicine integrating the lipidic derivative of 5-fluorouracil, miriplatin and PD-L1 siRNA for enhancing tumor therapy
An Lu, Yuhao Guo, Yi Yan, Lin Zhai, Xiangyu Wang, Weiran Cao, Zijie Li, Zhixia Zhao, Yujie Shi, Yuanjun Zhu, Xiaoyan Liu, Huining He, Zhiyu Wang, Jian-Cheng Wang
Chinese Chemical Letters.2024; 35(6): 108928. CrossRef - Watch and wait strategies for rectal cancer: A systematic review
In Ja Park
Precision and Future Medicine.2022; 6(2): 91. CrossRef - Intensified Total Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer: A Phase II Trial
F. De Felice, G. D'Ambrosio, F. Iafrate, A. Gelibter, F.M. Magliocca, D. Musio, S. Caponetto, G. Casella, I. Clementi, A. Picchetto, G. Sirgiovani, M. Parisi, C. Orciuoli, G. Torrese, G. De Toma, V. Tombolini, E. Cortesi
Clinical Oncology.2021; 33(12): 788. CrossRef - Efficacy and safety of sequential neoadjuvant chemotherapy and short-course radiation therapy followed by delayed surgery in locally advanced rectal cancer: a single-arm phase II clinical trial with subgroup analysis between the older and young patients
Alimohammad Bananzadeh, Ali Akbar Hafezi, NamPhong Nguyen, Shapour Omidvari, Ahmad Mosalaei, Niloofar Ahmadloo, Mansour Ansari, Mohammad Mohammadianpanah
Radiation Oncology Journal.2021; 39(4): 270. CrossRef - Induction Chemotherapy in Patients With Anal Canal Cancer: A Pilot Study
Francesca De Felice, Daniela Musio, Vincenzo Tombolini
Clinical Colorectal Cancer.2020; 19(3): e137. CrossRef
- Nanomedicine integrating the lipidic derivative of 5-fluorouracil, miriplatin and PD-L1 siRNA for enhancing tumor therapy
- Oncologic Outcomes of Organ Preserving Approaches in Patients With Rectal Cancer Treated With Preoperative Chemoradiotherapy
- In Ja Park, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
- Ann Coloproctol. 2019;35(2):65-71. Published online April 30, 2019
- DOI: https://doi.org/10.3393/ac.2019.03.17
- 5,933 View
- 129 Download
- 15 Web of Science
- 15 Citations
-
Abstract
PDF
- Purpose
We evaluated the oncologic outcomes of organ-preserving strategies in patients with rectal cancer treated with preoperative chemoradiotherapy (PCRT).
Methods
Between January 2008 and January 2013, 74 patients who underwent wait-and-watch (WW) (n = 42) and local excision (LE) (n = 32) were enrolled. Organ-preserving strategies were determined based on a combination of magnetic resonance imaging, sigmoidoscopy, and physical examination 4–6 weeks after completion of PCRT. The rectum sparing rate, 5-year recurrence-free survival (RFS), and overall survival (OS) were evaluated.
Results
The rectum was more frequently spared in the LE (100% vs. 87.5%, P = 0.018) at last follow-up. Recurrence occurred in 9 (28.1%) WW and 7 (16.7%) LE (P = 0.169). In the WW, 7 patients had only luminal regrowth and 2 had combined lung metastasis. In the LE, 2 (4.8%) had local recurrence only, 4 patients had distant metastasis, and 1 patient had local and distant metastasis. Among 13 patients who indicated salvage surgery (WW, n = 7; LE, n = 11), all in the WW received but all of LE refused salvage surgery (P = 0.048). The 5-year OS and 5-year RFS in overall patients was 92.7% and 76.9%, respectively, and were not different between WW and LE (P = 0.725, P = 0.129).
Conclusion
WW and LE were comparable in terms of 5-year OS and RFS. In the LE group, salvage treatment was performed much less among indicated patients. Therefore, methods to improve the oncologic outcomes of patients indicated for salvage treatment should be considered before local excision. -
Citations
Citations to this article as recorded by- Dynamic variation in a combined inflammation–tumor marker index during neoadjuvant chemotherapy and its value for organ-preservation decisions in gastric cancer
Ke Liu, Haiquan Qian, Shensi Chen, Shengjun Zhang, Wei Zhao
Open Life Sciences.2026;[Epub] CrossRef - Effectiveness of Organ Preservation for Locally Advanced Rectal Cancer With Complete Clinical Response After Neoadjuvant Chemoradiotherapy: Bayesian Network Meta-analysis
Kaibo Ouyang, Zifeng Yang, Yuesheng Yang, Zejian Lyu, Junjiang Wang, Yong Li
Diseases of the Colon & Rectum.2025; 68(3): 287. CrossRef - Rectal cancer approach strategies after neoadjuvant treatment – a systematic review and network meta-analysis
Cong Meng, Wenlong Shu, Liting Sun, Si Wu, Pengyu Wei, Jiale Gao, Jinyao Shi, Yang Li, Zhengyang Yang, Hongwei Yao, Zhongtao Zhang
International Journal of Surgery.2025; 111(4): 3078. CrossRef - Rectal Sparing Approaches after Neoadjuvant Treatment for Rectal Cancer: A Systematic Review and Meta-Analysis Comparing Local Excision and Watch and Wait
Quoc Riccardo Bao, Stefania Ferrari, Giulia Capelli, Cesare Ruffolo, Marco Scarpa, Amedea Agnes, Giuditta Chiloiro, Elisa Palazzari, Emanuele Damiano Luca Urso, Salvatore Pucciarelli, Gaya Spolverato
Cancers.2023; 15(2): 465. CrossRef - Organ preservation for early rectal cancer using preoperative chemoradiotherapy
Gyung Mo Son
Annals of Coloproctology.2023; 39(3): 191. CrossRef - Can pretreatment platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios predict long-term oncologic outcomes after preoperative chemoradiation followed by surgery for locally advanced rectal cancer?
Sang Hyun An, Ik Yong Kim
Annals of Coloproctology.2022; 38(3): 253. CrossRef - Multidisciplinary treatment strategy for early rectal cancer
Gyung Mo Son, In Young Lee, Sung Hwan Cho, Byung-Soo Park, Hyun Sung Kim, Su Bum Park, Hyung Wook Kim, Sang Bo Oh, Tae Un Kim, Dong Hoon Shin
Precision and Future Medicine.2022; 6(1): 32. CrossRef - Pretreatment inflammatory markers predicting treatment outcomes in colorectal cancer
Sanghyun An, Hongjin Shim, Kwangmin Kim, Bora Kim, Hui-Jae Bang, Hyejin Do, Hyang-Rae Lee, Youngwan Kim
Annals of Coloproctology.2022; 38(2): 97. CrossRef - Watch and wait strategies for rectal cancer: A systematic review
In Ja Park
Precision and Future Medicine.2022; 6(2): 91. CrossRef - The watch-and-wait strategy versus radical resection for rectal cancer patients with a good response (≤ycT2) after neoadjuvant chemoradiotherapy
Chungyeop Lee, In Ja Park, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
Annals of Surgical Treatment and Research.2022; 103(6): 350. CrossRef - Improvement in the Assessment of Response to Preoperative Chemoradiotherapy for Rectal Cancer Using Magnetic Resonance Imaging and a Multigene Biomarker
Eunhae Cho, Sung Woo Jung, In Ja Park, Jong Keon Jang, Seong Ho Park, Seung-Mo Hong, Jong Lyul Lee, Chan Wook Kim, Yong Sik Yoon, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
Cancers.2021; 13(14): 3480. CrossRef - Comparison between Local Excision and Radical Resection for the Treatment of Rectal Cancer in ypT0-1 Patients: An Analysis of the Clinicopathological Factors and Survival Rates
Soo Young Oh, In Ja Park, Young IL Kim, Jong-Lyul Lee, Chan Wook Kim, Yong Sik Yoon, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
Cancers.2021; 13(19): 4823. CrossRef - Functional outcomes after sphincter-preserving surgeries for low-lying rectal cancer: A review
Eun Jung Park, Seung Hyuk Baik
Precision and Future Medicine.2021; 5(4): 164. CrossRef - The risk of distant metastases in rectal cancer managed by a watch-and-wait strategy – A systematic review and meta-analysis
Joanna Socha, Lucyna Kępka, Wojciech Michalski, Karol Paciorek, Krzysztof Bujko
Radiotherapy and Oncology.2020; 144: 1. CrossRef - From Total Mesorectal Excision to Organ Preservation for the Treatment of Rectal Cancer
Seong Kyu Baek
Annals of Coloproctology.2019; 35(2): 51. CrossRef
- Dynamic variation in a combined inflammation–tumor marker index during neoadjuvant chemotherapy and its value for organ-preservation decisions in gastric cancer
- Does the Different Locations of Colon Cancer Affect the Oncologic Outcome? A Propensity-Score Matched Analysis
- Kwan Mo Yang, In Ja Park, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seok-Byung Lim, Na Young Kim, Shinae Hong, Chang Sik Yu, Jin Cheon Kim
- Ann Coloproctol. 2019;35(1):15-23. Published online February 28, 2019
- DOI: https://doi.org/10.3393/ac.2018.07.25
- 5,659 View
- 125 Download
- 4 Web of Science
- 3 Citations
-
Abstract
PDF
- Purpose
We evaluate the prognostic value of primary tumor location for oncologic outcomes in patients with colon cancer (CC).
Methods
CC patients treated with curative surgery between 2009 and 2012 were classified into 2 groups: right-sided colon cancer (RCC) and left-sided colon cancer (LCC). Recurrence-free survival (RFS) and overall survival (OS) were examined based on tumor stage. Propensity scores were created using eight variables (age, sex, T stage, N stage, histologic grade, presence of lymphovascular invasion/perineural invasion, and microsatellite instability status).
Results
Overall, 2,329 patients were identified. The 5-year RFSs for RCC and LCC patients were 89.7% and 88.4% (P = 0.328), respectively, and their 5-year OSs were 90.9% and 93.4% (P = 0.062). Multivariate survival analyses were carried out by using the Cox regression proportional hazard model. In the unadjusted analysis, a marginal increase in overall mortality was seen in RCC patients (hazard ratio [HR], 1.297; 95% confidence interval [CI], 0.987–1.704, P = 0.062); however, after multivariable adjustment, similar OSs were observed in those patients (HR, 1.219; 95% CI, 0.91–1.633; P = 0.183). After propensity-score matching with a total of 1,560 patients, no significant difference was identified (P = 0.183). A slightly worse OS was seen for stage III RCC patients (HR, 1.561; 95% CI, 0.967–2.522; P = 0.068) than for stage III LCC patients. The 5-year OSs for patients with stage III RCC and stage III LCC were 85.5% and 90.5%, respectively (P = 0.133).
Conclusion
Although the results are inconclusive, tumor location tended to be associated with OS in CC patients with lymph node metastasis, but it was not related to oncologic outcome. -
Citations
Citations to this article as recorded by- Prognostic value of primary tumor location in colorectal cancer: an updated meta-analysis
Hanieh Gholamalizadeh, Nima Zafari, Mahla Velayati, Hamid Fiuji, Mina Maftooh, Elnaz Ghorbani, Seyed Mahdi Hassanian, Majid Khazaei, Gordon A. Ferns, Elham Nazari, Amir Avan
Clinical and Experimental Medicine.2023; 23(8): 4369. CrossRef - Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation
Kristian-Christos Ngamsri, Christoph Jans, Rizki A. Putri, Katharina Schindler, Jutta Gamper-Tsigaras, Claudia Eggstein, David Köhler, Franziska M. Konrad
Frontiers in Immunology.2020;[Epub] CrossRef - Left colon as a novel high-risk factor for postoperative recurrence of stage II colon cancer
Liming Wang, Yasumitsu Hirano, Toshimasa Ishii, Hiroka Kondo, Kiyoka Hara, Nao Obara, Shigeki Yamaguchi
World Journal of Surgical Oncology.2020;[Epub] CrossRef
- Prognostic value of primary tumor location in colorectal cancer: an updated meta-analysis
Review
- Differences Regarding the Molecular Features and Gut Microbiota Between Right and Left Colon Cancer
- Kwangmin Kim, Ernes John T. Castro, Hongjin Shim, John Vincent G. Advincula, Young-Wan Kim
- Ann Coloproctol. 2018;34(6):280-285. Published online December 31, 2018
- DOI: https://doi.org/10.3393/ac.2018.12.17
- 10,302 View
- 277 Download
- 47 Web of Science
- 46 Citations
-
Abstract
PDF
- For many years, developmental and physiological differences have been known to exist between anatomic segments of the colorectum. Because of different outcomes, prognoses, and clinical responses to chemotherapy, the distinction between right colon cancer (RCC) and left colon cancer (LCC) has gained attention. Furthermore, variations in the molecular features and gut microbiota between right and LCCs have recently been a hot research topic. CpG island methylator phenotype-high, microsatellite instability-high colorectal cancers are more likely to occur on the right side whereas tumors with chromosomal instability have been detected in approximately 75% of LCC patients and 30% of RCC patients. The mutation rates of oncogenes and tumor suppressor genes also differ between RCC and LCC patients. Biofilm is more abundant in RCC patients than LLC patients, as are Prevotella, Selenomonas, and Peptostreptococcus. Conversely, Fusobacterium, Escherichia/Shigella, and Leptotrichia are more abundant in LCC patients compared to RCC patients. Distinctive characteristics are apparent in terms of molecular features and gut microbiota between right and LCC. However, how or to what extent these differences influence diverging oncologic outcomes remains unclear. Further clinical and translational studies are needed to elucidate the causative relationship between primary tumor location and prognosis.
-
Citations
Citations to this article as recorded by- Clostridioides difficile: A suspected pro-carcinogenic bacterium for gastrointestinal tumors
Ju Zou, Biyue Tian, Yuanyuan Xiao, Anhua Wu, Chunhui Li
Chinese Medical Journal.2026; 139(1): 7. CrossRef - Integrating E-cadherin expression levels with TNM staging for enhanced prognostic prediction in colorectal cancer patients
Jae-Ghi Lee, Ilkyu Park, Hannah Lee, Seungyoon Nam, Jisup Kim, Won-Suk Lee, Myunghee Kang, Jung Ho Kim
BMC Cancer.2025;[Epub] CrossRef - The Gut Microbiota and Colorectal Cancer: Understanding the Link and Exploring Therapeutic Interventions
Imen Zalila-Kolsi, Dhoha Dhieb, Hussam A. Osman, Hadjer Mekideche
Biology.2025; 14(3): 251. CrossRef - Diagnostic utility of the preoperative cachexia index for malnutrition in colorectal cancer: A prospective cohort study
Katarzyna Chawrylak, Wojciech Górski, Katarzyna Sędłak, Radoslaw Mlak, Marta Kaus, Agnieszka Hotloś, Zuzanna Chilimoniuk, Konrad Gładysz, Katarzyna Mielniczek, Magdalena Leśniewska, Zuzanna Pelc, Michał Bednarz, Wiktor Grela, Natalia Gniaź, Aleksandra Gór
Surgical Oncology.2025; 62: 102275. CrossRef - Differences in the expression of CMTM3 and SSTR2 genes in right and left colon tumors: A molecular insight into colorectal cancer
Tuğçe Binen, Etem Akbaş, Tahsin Çolak, Tuba Kara, Aslıhan Bakır, Badel İnce
Medical Oncology.2025;[Epub] CrossRef - Distinctive chromosomal, mutational and transcriptional profiling in colon versus rectal cancers
Maria Teresa De Angelis, Antonia Rizzuto, Angela Amaddeo, Carlo Sagnelli, Niccolò Vono, Michela Reda, Valentina Lise, Luca Parrillo, Carmela De Marco, Donatella Malanga, Gianluca Santamaria, Giuseppe Viglietto
Journal of Translational Medicine.2025;[Epub] CrossRef - Oral microbiota analysis of tongue coating in patients with esophageal adenocarcinoma
Huijie Wang, Jinfeng Wang, Jinli Liu, Xiaoyang Shi, Zhichao Wang, Xu Cao
Medicine.2025; 104(41): e45160. CrossRef - Genetic, Epidemiological, Clinical, and Therapeutic Trajectories in Colon and Rectal Cancers
Maurizio Capuozzo, Carmine Picone, Francesco Sabbatino, Mariachiara Santorsola, Francesco Caraglia, Domenico Iervolino, Roberto Sirica, Oreste Gualillo, Giordana Di Mauro, Rosa Castiello, Monica Ianniello, Alessia Maria Cossu, Angela Nebbioso, Lucia Altuc
Cancers.2025; 17(21): 3438. CrossRef - Expression of Human Endogenous Retrovirus Env Gene Product Is a Hallmark of Sidedness in Operable Colorectal Cancer
Maria Dolci, Ivan Civettini, Pietro Francesco Bagnoli, Wafa Toumi, Lucia Signorini, Roberto Crocchiolo, Kevin Kamau Maina, Federica Perego, Pasquale Ferrante, Carolina Scagnolari, Marco Bregni, Serena Delbue
Oncology.2025; 103(12): 1138. CrossRef - The gut microbiota and its biogeography
Giselle McCallum, Carolina Tropini
Nature Reviews Microbiology.2024; 22(2): 105. CrossRef - The role of gut microbiota and probiotics in preventing, treating, and boosting the immune system in colorectal cancer
Forough Masheghati, Mohammad Reza Asgharzadeh, Abbas Jafari, Naser Masoudi, Hadi Maleki-Kakelar
Life Sciences.2024; 344: 122529. CrossRef - Diet-mediated gut microbial community modulation and signature metabolites as potential biomarkers for early diagnosis, prognosis, prevention and stage-specific treatment of colorectal cancer
Mutebi John Kenneth, Hsin-Chi Tsai, Chuan-Yin Fang, Bashir Hussain, Yi-Chou Chiu, Bing-Mu Hsu
Journal of Advanced Research.2023; 52: 45. CrossRef - Microbiome and metabolic features of tissues and feces reveal diagnostic biomarkers for colorectal cancer
Jiahui Feng, Zhizhong Gong, Zhangran Sun, Juan Li, Na Xu, Rick F. Thorne, Xu Dong Zhang, Xiaoying Liu, Gang Liu
Frontiers in Microbiology.2023;[Epub] CrossRef - Metachronous Colorectal Adenomas Occur Close to the Index Lesion
Ria Rosser, Bernard M. Corfe, Keith S. Chapple
Journal of Clinical Gastroenterology.2023; 57(9): 937. CrossRef - Genetic heterogeneity of colorectal cancer and the microbiome
Marina A Senchukova
World Journal of Gastrointestinal Oncology.2023; 15(3): 443. CrossRef - Impact of Colorectal Cancer Sidedness and Location on Therapy and Clinical Outcomes: Role of Blood-Based Biopsy for Personalized Treatment
Sasha Waldstein, Marianne Spengler, Iryna V. Pinchuk, Nelson S. Yee
Journal of Personalized Medicine.2023; 13(7): 1114. CrossRef - Fusobacterium nucleatum-Mediated Alteration in Expression of VEGF and CCL3 Genes and KRAS Mutation in Colorectal Cancer Patients
Hataw Jalal Taher, Fouad Kamel
Jundishapur Journal of Microbiology.2023;[Epub] CrossRef - Risk of developing metachronous colorectal neoplasia after the resection of proximal versus distal adenomas
Yoon Suk Jung, Nam Hee Kim, Youngwoo Kim, Dong Il Park
Digestive and Liver Disease.2022; 54(4): 537. CrossRef - Faeces from malnourished colorectal cancer patients accelerate cancer progression
Xu Chao, Zhang Lei, Liu Hongqin, Wang Ziwei, Li Dechuan, Du Weidong, Xu Lu, Chen Haitao, Zhang Bo, Ju Haixing, Yao Qinghua
Clinical Nutrition.2022; 41(3): 632. CrossRef - Clinical and molecular profile of young adults with early‐onset colorectal cancer: Experience from four Australian tertiary centers
Derrick Ho Wai Siu, Arwa Ali, Angelina Tjokrowidjaja, Madhawa De Silva, Joanna Lee, Philip R. Clingan, Morteza Aghmesheh, Daniel Brungs, Cristina Mapagu, David Goldstein, Siobhan O'Neill, Winston S. Liauw, Katrin M. Sjoquist, David Thomas, Nick Pavlakis,
Asia-Pacific Journal of Clinical Oncology.2022; 18(6): 660. CrossRef - Microbial Characteristics of Common Tongue Coatings in Patients with Precancerous Lesions of the Upper Gastrointestinal Tract
Xiaoyu Kang, Bin Lu, Pan Xiao, Zhaolai Hua, Rui Shen, Jianping Wu, Juan Wu, Zhenfeng Wu, Chun Cheng, Junfeng Zhang, Enas Abdulhay
Journal of Healthcare Engineering.2022; 2022: 1. CrossRef - Colorectal microbiota after removal of colorectal cancer
Peter Cronin, Clodagh L Murphy, Maurice Barrett, Tarini Shankar Ghosh, Paola Pellanda, Eibhlis M O’Connor, Syed Akbar Zulquernain, Shane Kileen, Morgan McCourt, Emmet Andrews, Micheal G O’Riordain, Fergus Shanahan, Paul W O’Toole
NAR Cancer.2022;[Epub] CrossRef - Pretreatment inflammatory markers predicting treatment outcomes in colorectal cancer
Sanghyun An, Hongjin Shim, Kwangmin Kim, Bora Kim, Hui-Jae Bang, Hyejin Do, Hyang-Rae Lee, Youngwan Kim
Annals of Coloproctology.2022; 38(2): 97. CrossRef - Tumor tissue-specific bacterial biomarker panel for colorectal cancer: Bacteroides massiliensis, Alistipes species, Alistipes onderdonkii, Bifidobacterium pseudocatenulatum, Corynebacterium appendicis
Rizwana Hasan, Sudeep Bose, Rahul Roy, Debarati Paul, Saumitra Rawat, Pravin Nilwe, Neeraj K. Chauhan, Sangeeta Choudhury
Archives of Microbiology.2022;[Epub] CrossRef - Association of tumor-infiltrating lymphocytes with survival depends on primary tumor sidedness in stage III colon cancers (NCCTG N0147) [Alliance]
B. Saberzadeh-Ardestani, N.R. Foster, H.E. Lee, Q. Shi, S.R. Alberts, T.C. Smyrk, F.A. Sinicrope
Annals of Oncology.2022; 33(11): 1159. CrossRef - Fecal Luminal Factors from Patients with Gastrointestinal Diseases Alter Gene Expression Profiles in Caco-2 Cells and Colonoids
Luiza Holst, Cristina Iribarren, Maria Sapnara, Otto Savolainen, Hans Törnblom, Yvonne Wettergren, Hans Strid, Magnus Simrén, Maria K. Magnusson, Lena Öhman
International Journal of Molecular Sciences.2022; 23(24): 15505. CrossRef - Phosphorylated transducer and activator of transcription-3 (pSTAT3) immunohistochemical expression in paired primary and metastatic colorectal cancer
Esmeralda C. Marginean, Joanna Gotfrit, Horia Marginean, Daniel W. Yokom, Justin J. Bateman, Manijeh Daneshmand, Shelly Sud, Allen M. Gown, Derek Jonker, Timothy Asmis, Rachel A. Goodwin
Translational Oncology.2021; 14(2): 100996. CrossRef - Construction of a long noncoding RNA-based competing endogenous RNA network and prognostic signatures of left- and right-side colon cancer
Ke-zhi Li, Yi-xin Yin, Yan-ping Tang, Long Long, Ming-zhi Xie, Ji-lin Li, Ke Ding, Bang-li Hu
Cancer Cell International.2021;[Epub] CrossRef - Gut Microbiota as Potential Biomarker and/or Therapeutic Target to Improve the Management of Cancer: Focus on Colibactin-Producing Escherichia coli in Colorectal Cancer
Julie Veziant, Romain Villéger, Nicolas Barnich, Mathilde Bonnet
Cancers.2021; 13(9): 2215. CrossRef - Association of Habitual Preoperative Dietary Fiber Intake With Complications After Colorectal Cancer Surgery
Dieuwertje E. Kok, Melissa N. N. Arron, Tess Huibregtse, Flip M. Kruyt, Dirk Jan Bac, Henk K. van Halteren, Ewout A. Kouwenhoven, Evertine Wesselink, Renate M. Winkels, Moniek van Zutphen, Fränzel J. B. van Duijnhoven, Johannes H. W. de Wilt, Ellen Kampma
JAMA Surgery.2021; 156(9): 827. CrossRef - Resectable Colorectal Cancer: Current Perceptions on the Correlation of Recurrence Risk, Microbiota and Detection of Genetic Mutations in Liquid Biopsies
Andreas Koulouris, Christos Tsagkaris, Ippokratis Messaritakis, Nikolaos Gouvas, Maria Sfakianaki, Maria Trypaki, Vasiliki Spyrou, Manousos Christodoulakis, Elias Athanasakis, Evangelos Xynos, Maria Tzardi, Dimitrios Mavroudis, John Souglakos
Cancers.2021; 13(14): 3522. CrossRef - Effects of Helicobacter pylori Infection on the Oral Microbiota of Reflux Esophagitis Patients
Tian Liang, Fang Liu, Lijun Liu, Zhiying Zhang, Wenxue Dong, Su Bai, Lifeng Ma, Longli Kang
Frontiers in Cellular and Infection Microbiology.2021;[Epub] CrossRef - The Association of Gut Microbiota and Complications in Gastrointestinal-Cancer Therapies
Kevin M. Tourelle, Sebastien Boutin, Markus A. Weigand, Felix C. F. Schmitt
Biomedicines.2021; 9(10): 1305. CrossRef - Antibacterial Activity of T22, a Specific Peptidic Ligand of the Tumoral Marker CXCR4
Naroa Serna, José Vicente Carratalá, Oscar Conchillo-Solé, Carlos Martínez-Torró, Ugutz Unzueta, Ramón Mangues, Neus Ferrer-Miralles, Xavier Daura, Esther Vázquez, Antonio Villaverde
Pharmaceutics.2021; 13(11): 1922. CrossRef - Gut Microbiota Profiles in Early- and Late-Onset Colorectal Cancer: A Potential Diagnostic Biomarker in the Future
Murdani Abdullah, Ninik Sukartini, Saskia Aziza Nursyirwan, Rabbinu Rangga Pribadi, Hasan Maulahela, Amanda Pitarini Utari, Virly Nanda Muzellina, Agustinus Wiraatmadja, Kaka Renaldi
Digestion.2021; 102(6): 823. CrossRef - The gut microbiome in epilepsy
Birol Şafak, Bengü Altunan, Birol Topçu, Aynur Eren Topkaya
Microbial Pathogenesis.2020; 139: 103853. CrossRef - Therapeutic Targeting of the Colorectal Tumor Stroma
Wolf H. Fridman, Ian Miller, Catherine Sautès-Fridman, Annette T. Byrne
Gastroenterology.2020; 158(2): 303. CrossRef - Bacterial Biofilm and its Role in the Pathogenesis of Disease
Lene K. Vestby, Torstein Grønseth, Roger Simm, Live L. Nesse
Antibiotics.2020; 9(2): 59. CrossRef - Foes or Friends? Bacteria Enriched in the Tumor Microenvironment of Colorectal Cancer
Siyang Xu, Wen Yin, Yuling Zhang, Qimei Lv, Yijun Yang, Jin He
Cancers.2020; 12(2): 372. CrossRef - Esophageal microbiome signature in patients with Barrett’s esophagus and esophageal adenocarcinoma
Loris Riccardo Lopetuso, Marco Severgnini, Silvia Pecere, Francesca Romana Ponziani, Ivo Boskoski, Alberto Larghi, Gianluca Quaranta, Luca Masucci, Gianluca Ianiro, Tania Camboni, Antonio Gasbarrini, Guido Costamagna, Clarissa Consolandi, Giovanni Cammaro
PLOS ONE.2020; 15(5): e0231789. CrossRef - Unsuspected clinical presentation of coronavirus disease 2019: acute bowel disease
Marco Lotti, Michela Giulii Capponi, Dusanka Dokic, Paolo Bertoli, Alessandro Lucianetti
ANZ Journal of Surgery.2020; 90(9): 1772. CrossRef - Does Sidedness Matter in Unresectable Colorectal Cancer?
Suneel D. Kamath, Alok A. Khorana
Annals of Surgical Oncology.2019; 26(6): 1588. CrossRef - Morphological characteristics of mucinous adenocarcinoma of the colon and its embryogenetic premises
Yu. S. Korneva, R. V. Ukrainets
Colorectal Oncology.2019; 9(2): 16. CrossRef - Primary Tumor Sidedness Predicts Bevacizumab Benefit in Metastatic Colorectal Cancer Patients
Xia-Hong You, Can Wen, Zi-Jin Xia, Fan Sun, Yao Li, Wei Wang, Zhou Fang, Qing-Gen Chen, Lei Zhang, Yu-Huang Jiang, Xiao-Zhong Wang, Hou-Qun Ying, Zhen Zong
Frontiers in Oncology.2019;[Epub] CrossRef - Endoscopic gastric mucosal atrophy as a predictor of colorectal polyps: a large scale case-control study
Yoshinari Kawahara, Masaaki Kodama, Kazuhiro Mizukami, Tomoko Saito, Yuka Hirashita, Akira Sonoda, Kensuke Fukuda, Osamu Matsunari, Kazuhisa Okamoto, Ryo Ogawa, Tadayoshi Okimoto, Kazunari Murakami
Journal of Clinical Biochemistry and Nutrition.2019; 65(2): 153. CrossRef - Gut Microbiome: A Promising Biomarker for Immunotherapy in Colorectal Cancer
Sally Temraz, Farah Nassar, Rihab Nasr, Maya Charafeddine, Deborah Mukherji, Ali Shamseddine
International Journal of Molecular Sciences.2019; 20(17): 4155. CrossRef
- Clostridioides difficile: A suspected pro-carcinogenic bacterium for gastrointestinal tumors
Original Articles
- Management Outcomes of Colonoscopic Perforations Are Affected by the General Condition of the Patients
- Jae Ho Park, Kyung Jong Kim
- Ann Coloproctol. 2018;34(1):16-22. Published online February 28, 2018
- DOI: https://doi.org/10.3393/ac.2018.34.1.16
- 6,129 View
- 110 Download
- 1 Web of Science
- 1 Citations
-
Abstract
PDF
Purpose The management of a colonoscopic perforation (CP) varies from conservative to surgical. The objective of this study was to evaluate the outcomes between surgical and conservative treatment of patients with a CP.
Methods From 2003 to 2016, the medical records of patients with CP were retrospectively reviewed. Patients were divided into 2 groups depending on whether they initially received conservative or surgical treatment.
Results During the study period, a total of 48 patients with a CP were treated. Among them, 5 patients had underlying colorectal cancer and underwent emergency radical cancer surgery; these patients were excluded. The mean age of the remaining 43 patients was 64.5 years old, and the most common perforation site was the sigmoid colon (15 patients). The initial conservative care group included 16 patients, and the surgery group included 27 patients. In the conservative group, 5 patients required conversion to surgery (failure rate: 5 of 16 [31.3%]). Of the surgery group, laparoscopic surgery was performed on 19 patients and open surgery on 8 patients, including 2 conversion cases. Major postoperative complications developed in 11 patients (34.4%), and postoperative mortality developed in 4 patients (12.5%). The only predictor for poor prognosis after surgery was a high American Society of Anesthesiologists physical status classification.
Conclusion In this study, conservative treatment for patients with a CP had a relatively high failure rate. Furthermore, surgical treatment showed significant rates of complications and mortality, which depended on the general status of the patients.
-
Citations
Citations to this article as recorded by- Multicenter retrospective evaluation of ileocecocolic perforations associated with diagnostic lower gastrointestinal endoscopy in dogs and cats
Vanessa L. Woolhead, Jacqueline C. Whittemore, Sarah A. Stewart
Journal of Veterinary Internal Medicine.2020; 34(2): 684. CrossRef
- Multicenter retrospective evaluation of ileocecocolic perforations associated with diagnostic lower gastrointestinal endoscopy in dogs and cats
- Clinical Features and Factors Associated With Surgical Treatment in Patients With Complicated Colonic Diverticulitis
- Pill Sun Paik, Jung-A Yun
- Ann Coloproctol. 2017;33(5):178-183. Published online October 31, 2017
- DOI: https://doi.org/10.3393/ac.2017.33.5.178
- 7,065 View
- 74 Download
- 6 Web of Science
- 6 Citations
-
Abstract
PDFSupplementary Material
Purpose Colonic diverticulitis is uncommon in Korea, but the incidence is rapidly increasing nowadays. The clinical features and the factors associated with complications of diverticulitis are important for properly treating the disease.
Methods A retrospective review of the medical records of 225 patients that were prospectively collected between October 2007 and September 2016 was conducted.
Results Diverticulitis was detected mainly in men and women aged 30 to 50 years. Diverticulitis more frequently affected the right colon (n = 194, 86.2%), but age was higher in case of left colonic involvement (42 years vs. 57 years, P < 0.001). Percentages of comorbidities (65.6% vs. 23.8%, P < 0.001), complications (65.6% vs. 6.2%, P < 0.001), and surgical treatment (50.0% vs. 4.1%, P < 0.001) were significantly higher in patients with left colonic diverticulitis. In the multivariate analysis, a risk factor for complicated diverticulitis was left colonic involvement (P < 0.001; relative risk [RR], 47.108; 95% confidence interval [CI], 12.651–175.413). In complicated diverticulitis, age over 50 was the only significant risk factor for surgical treatment (P = 0.024; RR, 19.350; 95% CI, 1.474–254.023).
Conclusion In patients over 50 years of age with left colonic diverticulitis, a preventive colectomy should be reconsidered as one of the options for treatment.
-
Citations
Citations to this article as recorded by- Platelet to lymphocyte ratio is a risk factor for failure of non-operative treatment of colonic diverticulitis
Jong Ho Kim, Sang Hyup Han, Jin-Won Lee, Haesung Kim, Jeonghee Han
Scientific Reports.2023;[Epub] CrossRef - Diagnosis and management of acute colonic diverticulitis: results of a survey among Korean gastroenterologists
Jae Gon Lee, Yong Eun Park, Ji Young Chang, Hyun Joo Song, Duk Hwan Kim, Young Joo Yang, Byung Chang Kim, Shin Hee Lee, Myung-Won You, Seong-Eun Kim
The Korean Journal of Internal Medicine.2023; 38(5): 672. CrossRef - Management and long-term outcomes of acute right colonic diverticulitis and risk factors of recurrence
Zhilong Ma, Weiwei Liu, Jia Zhou, Le Yao, Wangcheng Xie, Mingqi Su, Jin Yang, Jun Shao, Ji Chen
BMC Surgery.2022;[Epub] CrossRef - Predictive factors for conservative treatment failure of right colonic diverticulitis
Youn Young Park, Soomin Nam, Jeong Hee Han, Jaeim Lee, Chinock Cheong
Annals of Surgical Treatment and Research.2021; 100(6): 347. CrossRef - Laparoscopic diverticulectomy versus non-operative treatment for uncomplicated right colonic diverticulitis
Le Huy Luu, Nguyen Lam Vuong, Vo Thi Hong Yen, Do Thi Thu Phuong, Bui Khac Vu, Nguyen Viet Thanh, Nguyen Thien Khanh, Nguyen Van Hai
Surgical Endoscopy.2020; 34(5): 2019. CrossRef - Meta‐analysis of the demographic and prognostic significance of right‐sided versus left‐sided acute diverticulitis
S. Hajibandeh, S. Hajibandeh, N. J. Smart, A. Maw
Colorectal Disease.2020; 22(12): 1908. CrossRef
- Platelet to lymphocyte ratio is a risk factor for failure of non-operative treatment of colonic diverticulitis
- Does Anastomosis Configuration Influence Long-term Outcomes in Patients With Crohn Disease?
- Parajuli Anuj, Yong Sik Yoon, Chang Sik Yu, Jong Lyul Lee, Chan Wook Kim, In Ja Park, Seok-Byung Lim, Jin Cheon Kim
- Ann Coloproctol. 2017;33(5):173-177. Published online October 31, 2017
- DOI: https://doi.org/10.3393/ac.2017.33.5.173
- 6,106 View
- 71 Download
- 10 Web of Science
- 9 Citations
-
Abstract
PDF
Purpose In this study, we evaluated the role of various anastomoses in surgical recurrence for patients with Crohn disease (CD).
Methods We analyzed data retrospectively from consecutive laparotomy cases involving complicated CD between 1991 and 2008. Clinical data were compared in terms of reoperation-free survival (RFS) according to the types of anastomoses, the materials used for the anastomoses, and the operating surgeon.
Results Of 233 patients with entero-enteric or entero-colic anastomoses, 199 (85%), 11 (5%), and 23 (10%) experienced side-to-side (SS), side-to-end (SE), and end-to-end (EE) anastomoses, respectively. The SS group had the following characteristics: more extensive bowel involvement, frequent obstruction, and greater stapler use; the SS anastomoses were also frequently made by specialized surgeons (P < 0.001–0.004). EE anastomoses were frequently made by general surgeons using a hand-sewing technique (P < 0.001). No differences in RFS were noted among the 3 groups according to the type of anastomosis and the operating surgeon. However, the hand-sewn group showed better RFS than the stapler group (P = 0.04).
Conclusion The roles of the anastomotic configuration, the material used, and the operating surgeon were not significantly correlated with reoperations or complications in our retrospective CD cohort, irrespective of the higher risk of anastomosis site stricture for EE anastomoses.
-
Citations
Citations to this article as recorded by- Anastomosis after Bowel Resection for Crohn's Disease: State of the Art Review
Carla Newton, Alessandro Fichera
Clinics in Colon and Rectal Surgery.2025; 38(02): 104. CrossRef - Advances in endoscopy in IBD diagnostics and management
Joana Roseira, Maria Manuela Estevinho, Beatriz Gros, Irene Marafini, Virginia Solitano, Paula Sousa, Cristina Carretero, Winnie Zou, Nasim Parsa, Aline Charabaty, Lumir Kunovsky
Best Practice & Research Clinical Gastroenterology.2025; 78: 102055. CrossRef - New anti-mesenteric delta-shaped stapled anastomosis: Technical report with short-term postoperative outcomes in patients with Crohn’s disease
Jong Lyul Lee, Yong Sik Yoon, Hyun Gu Lee, Young Il Kim, Min Hyun Kim, Chan Wook Kim, In Ja Park, Seok-Byung Lim, Chang Sik Yu
World Journal of Gastrointestinal Surgery.2024; 16(8): 2592. CrossRef - Results of the Eighth Scientific Workshop of ECCO: Pathophysiology and Risk Factors of Postoperative Crohn’s Disease Recurrence after an Ileocolonic Resection
Pauline Rivière, Gabriele Bislenghi, Nassim Hammoudi, Bram Verstockt, Steven Brown, Melissa Oliveira-Cunha, Willem Bemelman, Gianluca Pellino, Paulo Gustavo Kotze, Gabriele Dragoni, Mariangela Allocca, Nurulamin M Noor, Lieven Pouillon, Míriam Mañosa, Edo
Journal of Crohn's and Colitis.2023; 17(10): 1557. CrossRef - Ileocolic Resection for Crohn Disease: The Influence of Different Surgical Techniques on Perioperative Outcomes, Recurrence Rates, and Endoscopic Surveillance
Benjamin Click, Amit Merchea, Dorin T Colibaseanu, Miguel Regueiro, Francis A Farraye, Luca Stocchi
Inflammatory Bowel Diseases.2022; 28(2): 289. CrossRef - Anastomotic Techniques for Abdominal Crohn's Disease: Tricks and Tips
Marco Bertucci Zoccali, Alessandro Fichera
Journal of Laparoendoscopic & Advanced Surgical Techniques.2021; 31(8): 861. CrossRef - Short-term and long-term outcomes of laparoscopic vs open ileocolic resection in patients with Crohn's disease: Propensity-score matching analysis
Shin Jeong Pak, Young Il Kim, Yong Sik Yoon, Jong Lyul Lee, Jung Bok Lee, Chang Sik Yu
World Journal of Gastroenterology.2021; 27(41): 7159. CrossRef - The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Surgical Management of Crohn’s Disease
Amy L. Lightner, Jon D. Vogel, Joseph C. Carmichael, Deborah S. Keller, Samir A. Shah, Uma Mahadevan, Sunanda V. Kane, Ian M. Paquette, Scott R. Steele, • Daniel L. Feingold
Diseases of the Colon & Rectum.2020; 63(8): 1028. CrossRef - Correlation Between Anastomotic Configuration and Long-term Outcomes in Surgery for Crohn Disease
Jin-Su Kim, Ji-Yeon Kim
Annals of Coloproctology.2017; 33(5): 159. CrossRef
- Anastomosis after Bowel Resection for Crohn's Disease: State of the Art Review
- Prognostic Significance of Mucinous Histologic Subtype on Oncologic Outcomes in Patients With Colorectal Cancer
- Sare Hosseini, Ali Mohammad Bananzadeh, Roham Salek, Mohammad Zare-Bandamiri, Ali Taghizadeh Kermani, Mohammad Mohammadianpanah
- Ann Coloproctol. 2017;33(2):57-63. Published online April 28, 2017
- DOI: https://doi.org/10.3393/ac.2017.33.2.57
- 6,791 View
- 52 Download
- 20 Web of Science
- 15 Citations
-
Abstract
PDF
Purpose Mucinous adenocarcinomas account for about 10% of all colorectal cancers. This study aimed to investigate the prognostic impact of mucinous histologic subtype on oncologic outcomes in patients with colorectal cancer.
Methods This retrospective study was performed at two large tertiary university hospitals. We analyzed the characteristics, prognostic factors, and survival of patients with colorectal cancer who were treated and followed up between 2000 and 2013.
Results Totally, 144 of 1,268 patients with a colorectal adenocarcinoma (11.4%) had mucinous histologic subtype. Statistically significant results found in this research are as follows: Mucinous histologic subtype tended to present in younger patients and to have larger tumor size, higher histologic grade, higher node stage, larger number of positive nodes, and higher rate of perineural invasion compared to nonmucinous histologic subtype. On the univariate analysis, mucinous subtype was a prognostic factor for disease-free and overall survival. On the multivariate analysis, primary tumor location, node stage and lymphatic-vascular invasion were independent prognostic factors for the local control rate. Rectal tumor location, higher disease stage, tumor grade II, and presence of lymphatic-vascular invasion had negative influences on disease-free survival, as did rectal tumor location, higher disease stage and presence of lymphatic-vascular invasion on overall survival.
Conclusion Mucinous histologic subtype was associated with some adverse pathologic features in patients with colorectal cancer; however, it was not an independent prognostic factor for oncologic outcome.
-
Citations
Citations to this article as recorded by- Comparing the Histopathologic Patterns and Survival Outcomes of Mucinous vs Non-mucinous Colorectal Adenocarcinoma: A Systematic Review and Meta-Analysis
Jane Nnanemere, Akinyele Oladimeji, Sarah Waseem, Ifelunwa M Osanakpo, Aminat D Lawal , Moses C Odoeke, Joshua T Green
Cureus.2026;[Epub] CrossRef - Association between lymphovascular invasion and lymph node metastases in colon cancer: A National Cancer Database analysis
Sameh Hany Emile, Nir Horesh, Zoe Garoufalia, Anjelli Wignakumar, Marylise Boutros, Steven D. Wexner
Colorectal Disease.2025;[Epub] CrossRef - Comprehensive Overview of Molecular, Imaging, and Therapeutic Challenges in Rectal Mucinous Adenocarcinoma
Mihaela Berar, Andra Ciocan, Emil Moiș, Luminița Furcea, Călin Popa, Răzvan Alexandru Ciocan, Florin Zaharie, Cosmin Puia, Nadim Al Hajjar, Cosmin Caraiani, Ioana Rusu, Florin Graur
International Journal of Molecular Sciences.2025; 26(2): 432. CrossRef - Clinicopathological and prognostic features of colorectal mucinous adenocarcinomas: a systematic review and meta-analysis
Xiao Wang, Haoran Wang, Haoqing He, Kai Lv, Wenguang Yuan, Jingbo Chen, Hui Yang
BMC Cancer.2024;[Epub] CrossRef - Multi gene mutation signatures in colorectal cancer patients: predict for the diagnosis, pathological classification, staging and prognosis
Yan Zhuang, Hailong Wang, Da Jiang, Ying Li, Lixia Feng, Caijuan Tian, Mingyu Pu, Xiaowei Wang, Jiangyan Zhang, Yuanjing Hu, Pengfei Liu
BMC Cancer.2021;[Epub] CrossRef - Clinicopathological Features and Survival of Signet-Ring Cell Carcinoma and Mucinous Adenocarcinoma of Right Colon, Left Colon, and Rectum
Lili Zhu, Chunrun Ling, Tao Xu, Jinglin Zhang, Yujie Zhang, Yingjie Liu, Chao Fang, Lie Yang, Wen Zhuang, Rui Wang, Jie Ping, Mojin Wang
Pathology and Oncology Research.2021;[Epub] CrossRef - Identification of Potential Biomarkers and Biological Pathways for Poor Clinical Outcome in Mucinous Colorectal Adenocarcinoma
Chang Woo Kim, Jae Myung Cha, Min Seob Kwak
Cancers.2021; 13(13): 3280. CrossRef - Clinical significance of mucinous component in colorectal adenocarcinoma: a propensity score-matched study
Chuanwang Yan, Hui Yang, Lili Chen, Ran Liu, Wei Shang, Wenguang Yuan, Fei Yang, Qing Sun, Lijian Xia
BMC Cancer.2021;[Epub] CrossRef - Incidence and prognosis of pulmonary metastasis in colorectal cancer: a population-based study
Yizhi Ge, Shijun Lei, Bo Cai, Xiang Gao, Guobin Wang, Lin Wang, Zheng Wang
International Journal of Colorectal Disease.2020; 35(2): 223. CrossRef - Association between aberrant dynein cytoplasmic�1 light intermediate chain�1 expression levels, mucins and chemosensitivity in colorectal cancer
Chun‑Chao Chang, Kuo‑Ching Chao, Chi‑Jung Huang, Chih‑Sheng Hung, Yen‑Chieh Wang
Molecular Medicine Reports.2020;[Epub] CrossRef - Clinical impact of non-predominant histopathological subtypes on the long-term prognosis of colorectal cancer patients in Japan
Heita Ozawa, Shinichi Yamauchi, Hiroki Nakanishi, Junichi Sakamoto, Shin Fujita, Kenichi Sugihara
International Journal of Colorectal Disease.2020; 35(12): 2257. CrossRef - Predictive Significance of Mucinous Histology on Pathologic Complete Response Rate Following Capecitabine-Based Neoadjuvant Chemoradiation in Rectal Cancer: a Comparative Study
Sare Hosseini, NamPhong Nguyen, Mohammad Mohammadianpanah, Sepideh Mirzaei, Ali Mohammad Bananzadeh
Journal of Gastrointestinal Cancer.2019; 50(4): 716. CrossRef - Impact of histological subtype on the prognosis of patients undergoing surgery for colon cancer
Fabio Bagante, Gaya Spolverato, Eliza Beal, Katiuscha Merath, Qinyu Chen, Ozgür Akgül, Robert A. Anders, Timothy M. Pawlik
Journal of Surgical Oncology.2018; 117(7): 1355. CrossRef - SCF/c-KIT Signaling Increased Mucin2 Production by Maintaining Atoh1 Expression in Mucinous Colorectal Adenocarcinoma
Ping Shen, Shu Yang, Haimei Sun, Guilan Li, Bo Wu, Fengqing Ji, Tingyi Sun, Deshan Zhou
International Journal of Molecular Sciences.2018; 19(5): 1541. CrossRef - Mucinous Subtype in Patients With Colorectal Cancer
Hyung Jin Kim
Annals of Coloproctology.2017; 33(2): 44. CrossRef
- Comparing the Histopathologic Patterns and Survival Outcomes of Mucinous vs Non-mucinous Colorectal Adenocarcinoma: A Systematic Review and Meta-Analysis
- Management of Colonic Diverticulitis Tailored to Location and Severity: Comparison of the Right and the Left Colon
- Byeoung Hoon Chung, Gi Won Ha, Min Ro Lee, Jong Hun Kim
- Ann Coloproctol. 2016;32(6):228-233. Published online December 31, 2016
- DOI: https://doi.org/10.3393/ac.2016.32.6.228
- 6,646 View
- 100 Download
- 24 Web of Science
- 24 Citations
-
Abstract
PDF
Purpose This study assessed optimal management of colonic diverticulitis as functions of disease location and severity and factors associated with complicated diverticulitis.
Methods This retrospective review analyzed 202 patients diagnosed between 2007 and 2014 at Chonbuk National University Hospital, South Korea, with colonic diverticulitis by using abdominopelvic computed tomography. Diverticulitis location was determined, and disease severity was categorized using the modified Hinchey classification.
Results Patients included 108 males (53.5%) and 94 females (46.5%); of these, 167 patients (82.7%) were diagnosed with right-sided and 35 (17.3%) with left-sided colonic diverticulitis. Of the 167 patients with right-sided colonic diverticulitis, 12 (7.2%) had complicated and 155 (92.8%) had uncomplicated diverticulitis; of these, 157 patients (94.0%) were successfully managed conservatively. Of the 35 patients with left-sided colonic diverticulitis, 23 (65.7%) had complicated and 12 (34.3%) had uncomplicated diverticulitis; of these, 23 patients (65.7%) were managed surgically. Among patients with right-sided diverticulitis, those with complicated disease were significantly older (54.3 ± 12.7 years vs. 42.5 ± 13.4 years, P = 0.004) and more likely to be smokers (66.7% vs. 32.9%, P = 0.027) than those with uncomplicated disease. However, among patients with left-sided diverticulitis, those with complicated disease had significantly lower body mass index (BMI; 21.9 ± 4.7 kg/m2 vs. 25.8 ± 4.3 kg/m2, P = 0.021) than those with uncomplicated disease.
Conclusion Conservative management may be effective in patients with right-sided diverticulitis and patients with uncomplicated left-sided colonic diverticulitis. Surgical management may be required for patients with complicated left-sided diverticulitis. Factors associated with complicated diverticulitis include older age, smoking and lower BMI.
-
Citations
Citations to this article as recorded by- The outcomes of right and left complicated colonic diverticulitis
Anh Tuan Nguyen, Quang Tien Pham, Hoi Van Tran, Hoang Viet Truong, Loc Huynh Tran
Surgery Open Science.2025; 27: 31. CrossRef - Right‐sided acute diverticulitis in a North African country: Presentation and management in one surgical center
Laila Jedidi, Aymen Mabrouk, Hela Ghali, Anis Ben Dhaou, Senda Ben Lahouel, Sami Daldoul, Houyem Said Latiri, Mounir Ben Moussa
World Journal of Surgery.2024; 48(6): 1509. CrossRef - Current diagnosis and management of acute colonic diverticulitis: What you need to know
Lisa M. Kodadek, Kimberly A. Davis
Journal of Trauma and Acute Care Surgery.2024; 97(1): 1. CrossRef - Comparison of surgical management and outcomes of acute right
colic and sigmoid diverticulitis: a French national retrospective cohort study
E. Karam, C. Sabbagh, L. Beyer-Bergeot, P. Zerbib, V. Bridoux, G. Manceau, Y. Panis, E. Buscail, A. Venara, I. Khaoudy, M. Gaillard, M. Viennet, A. Thobie, B. Menahem, C. Eveno, C. Bonnel, J.-Y. Mabrut, B. Badic, C. Godet, Y. Eid, E. Duchalais, Z. Lakkis,
Techniques in Coloproctology.2024;[Epub] CrossRef - Source control in emergency general surgery: WSES, GAIS, SIS-E, SIS-A guidelines
Federico Coccolini, Massimo Sartelli, Robert Sawyer, Kemal Rasa, Bruno Viaggi, Fikri Abu-Zidan, Kjetil Soreide, Timothy Hardcastle, Deepak Gupta, Cino Bendinelli, Marco Ceresoli, Vishal G. Shelat, Richard ten Broek, Gian Luca Baiocchi, Ernest E. Moore, Ib
World Journal of Emergency Surgery.2023;[Epub] CrossRef - Diagnosis and management of acute colonic diverticulitis: results of a survey among Korean gastroenterologists
Jae Gon Lee, Yong Eun Park, Ji Young Chang, Hyun Joo Song, Duk Hwan Kim, Young Joo Yang, Byung Chang Kim, Shin Hee Lee, Myung-Won You, Seong-Eun Kim
The Korean Journal of Internal Medicine.2023; 38(5): 672. CrossRef - Right-sided diverticulitis in a Western population
Adi Rov, Anat Ben-Ari, Eyal Barlev, David Pelcman, Sergio Susmalian, Haim Paran
International Journal of Colorectal Disease.2022; 37(6): 1251. CrossRef - Emergency surgery comparison of right versus left acute colonic diverticulitis: A 10-year outcome analysis
JS Tsang, Chi Chung Foo, Jeremy Yip, Hok Kwok Choi, Wai Lun Law, Oswens Siu Hung Lo
The Surgeon.2021; 19(3): 150. CrossRef - Elective surgical management of diverticulitis
Jordan M. Rook, Jill Q. Dworsky, Thomas Curran, Sudeep Banerjee, Mary R. Kwaan
Current Problems in Surgery.2021; 58(5): 100876. CrossRef - Special Situations in the Management of Diverticular Disease
Elizabeth H. Wood, Michael M. Sigman, Dana M. Hayden
Clinics in Colon and Rectal Surgery.2021; 34(02): 121. CrossRef - Routine colonoscopy may be needed for uncomplicated acute right colonic diverticulitis
Kil-yong Lee, Jaeim Lee, Youn Young Park, Seong Taek Oh
BMC Gastroenterology.2021;[Epub] CrossRef - WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections
Massimo Sartelli, Federico Coccolini, Yoram Kluger, Ervis Agastra, Fikri M. Abu-Zidan, Ashraf El Sayed Abbas, Luca Ansaloni, Abdulrashid Kayode Adesunkanmi, Boyko Atanasov, Goran Augustin, Miklosh Bala, Oussama Baraket, Suman Baral, Walter L. Biffl, Marja
World Journal of Emergency Surgery.2021;[Epub] CrossRef - Right sided diverticulitis in western countries: A review
Angelo Gabriele Epifani, Diletta Cassini, Roberto Cirocchi, Caterina Accardo, Francesca Di Candido, Massimiliano Ardu, Gianandrea Baldazzi
World Journal of Gastrointestinal Surgery.2021; 13(12): 1721. CrossRef - Difference in Clinical Features between Right- and Left-Sided Acute Colonic Diverticulitis
Kil-yong Lee, Jaeim Lee, Youn Young Park, Younglim Kim, Seong Taek Oh
Scientific Reports.2020;[Epub] CrossRef - 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting
Massimo Sartelli, Dieter G. Weber, Yoram Kluger, Luca Ansaloni, Federico Coccolini, Fikri Abu-Zidan, Goran Augustin, Offir Ben-Ishay, Walter L. Biffl, Konstantinos Bouliaris, Rodolfo Catena, Marco Ceresoli, Osvaldo Chiara, Massimo Chiarugi, Raul Coimbra,
World Journal of Emergency Surgery.2020;[Epub] CrossRef - Clinical Characteristics of Right Colonic Diverticulitis: A Comparison of Ileocecal Diverticulitis and Hepatic Flexure Diverticulitis
Yoshihisa Fujita, Fumihiko Ishikawa, Shigeyuki Kamata
Nippon Daicho Komonbyo Gakkai Zasshi.2020; 73(6): 244. CrossRef - Meta‐analysis of the demographic and prognostic significance of right‐sided versus left‐sided acute diverticulitis
S. Hajibandeh, S. Hajibandeh, N. J. Smart, A. Maw
Colorectal Disease.2020; 22(12): 1908. CrossRef - Long-term outcome and management of right colonic diverticulitis in western countries: Multicentric Retrospective Study
L. Courtot, V. Bridoux, Z. Lakkis, G. Piessen, G. Manceau, A. Mulliri, G. Meurette, A. Bouayed, A. Vénara, B. Blanc, N. Tabchouri, E. Salamé, M. Ouaïssi
Journal of Visceral Surgery.2019; 156(4): 296. CrossRef - Résultats à long terme et prise en charge des diverticulites du colon droit dans les pays occidentaux : étude rétrospective multicentrique
L. Courtot, V. Bridoux, Z. Lakkis, G. Piessen, G. Manceau, A. Mulliri, G. Meurette, A. Bouayed, A. Vénara, B. Blanc, N. Tabchouri, E. Salamé, M. Ouaïssi
Journal de Chirurgie Viscérale.2019; 156(4): 322. CrossRef - Prospective randomized clinical trial of uncomplicated right-sided colonic diverticulitis: antibiotics versus no antibiotics
Jeong Yeon Kim, Sung Gil Park, Hee Joon Kang, Young Ah Lim, Kyung Ho Pak, Tae Yoo, Won Tae Cho, Dong Woo Shin, Jong Wan Kim
International Journal of Colorectal Disease.2019; 34(8): 1413. CrossRef - Predictive Factors Affecting the Clinical Course of Patients With Diverticulitis: Who Needs Hospital Management?
Taeyoung Yoo, Keun Ho Yang, Jungbin Kim, Inseok Park, Hyunjin Cho, Geumhee Gwak, Byung Noe Bae, Ki Hwan Kim
Annals of Coloproctology.2018; 34(1): 23. CrossRef - Perforated diverticulitis: is the right and left difference present here too?
Nicholas Yock Teck Soh, Nan Zun Teo, Carrie Jen Hsi Tan, Shivani Rajaraman, Marianne Tsang, Calvin Jian Ming Ong, Ramesh Wijaya
International Journal of Colorectal Disease.2018; 33(5): 525. CrossRef - Clinical Features and Factors Associated With Surgical Treatment in Patients With Complicated Colonic Diverticulitis
Pill Sun Paik, Jung-A Yun
Annals of Coloproctology.2017; 33(5): 178. CrossRef - What is the Difference Between Right- and Left-Sided Colonic Diverticulitis?
Chang-Nam Kim
Annals of Coloproctology.2016; 32(6): 206. CrossRef
- The outcomes of right and left complicated colonic diverticulitis
- Efficacy and Safety of Low-Dose-Rate Endorectal Brachytherapy as a Boost to Neoadjuvant Chemoradiation in the Treatment of Locally Advanced Distal Rectal Cancer: A Phase-II Clinical Trial
- Shapour Omidvari, Shadi Zohourinia, Mansour Ansari, Leila Ghahramani, Mohammad Zare-Bandamiri, Ahmad Mosalaei, Niloofar Ahmadloo, Saeedeh Pourahmad, Hamid Nasrolahi, Sayed Hasan Hamedi, Mohammad Mohammadianpanah
- Ann Coloproctol. 2015;31(4):123-130. Published online August 31, 2015
- DOI: https://doi.org/10.3393/ac.2015.31.4.123
- 6,051 View
- 35 Download
- 11 Web of Science
- 14 Citations
-
Abstract
PDF
Purpose Despite advances in rectal cancer treatment over the last decade, local control and risk of late side effects due to external beam radiation therapy (EBRT) remain as concerns. The present study aimed to investigate the efficacy and the safety of low-dose-rate endorectal brachytherapy (LDRBT) as a boost to neoadjuvant chemoradiation for use in treating locally advanced distal rectal adenocarcinomas.
Methods This phase-II clinical trial included 34 patients (as the study arm) with newly diagnosed, locally advanced (clinical T3-T4 and/or N1/N2, M0) lower rectal cancer. For comparative analysis, 102 matched patients (as the historical control arm) with rectal cancer were also selected. All the patients were treated with LDRBT (15 Gy in 3 fractions) and concurrent chemoradiation (45-50.4 Gy). Concurrent chemotherapy consisted of oxaliplatin 130 mg/m2 intravenously on day 1 plus oral capecitabine 825 mg/m2 twice daily during LDRBT and EBRT.
Results The study results revealed a significant differences between the study arm and the control arm in terms in the pathologic tumor size (2.1 cm vs. 3.6 cm, P = 0.001), the pathologic tumor stage (35% T3-4 vs. 65% T3-4, P = 0.003), and the pathologic complete response (29.4% vs. 11.7%, P < 0.028). Moreover, a significantly higher dose of EBRT (P = 0.041) was found in the control arm, and a longer time to surgery was observed in the study arm (P < 0.001). The higher rate of treatment-related toxicities, such as mild proctitis and anemia, in the study arm was tolerable and easily manageable.
Conclusion A boost of LDRBT can optimize the pathologic complete response, with acceptable toxicities, in patients with distal rectal cancer.
-
Citations
Citations to this article as recorded by- Intraoperative low-dose rate brachytherapy as an adjunct to surgery for marginally resectable rectal and recurrent anorectal carcinomas
Mustafa M. Al Balushi, Teresia M. Perkins, Kee-Young Shin, Ivan M. Buzurovic, Simon G. Talbot, Joel E. Goldberg, Desmond A. O’Farrell, Martin T. King, Harvey J. Mamon, Philip M. Devlin
Brachytherapy.2025; 24(6): 931. CrossRef - Neoadjuvant Therapy for Organ Preservation in Locally Advanced Rectal Cancer: A Review
Liangting Qiu, Jianjun Li
Therapeutics and Clinical Risk Management.2025; Volume 21: 1289. CrossRef - Examining external control arms in oncology: A scoping review of applications to date
Eliya Farah, Matthew Kenney, Matthew T. Warkentin, Winson Y. Cheung, Darren R. Brenner
Cancer Medicine.2024;[Epub] CrossRef - Brachytherapy of rectal cancer: comparative characteristics of techniques (review)
Roman V. Novikov, Sergey N. Novikov
Koloproktologia.2023; 22(3): 158. CrossRef - Neoadjuvant Radiotherapy Dose Escalation in Locally Advanced Rectal Cancer: a Systematic Review and Meta-analysis of Modern Treatment Approaches and Outcomes
N. Hearn, D. Atwell, K. Cahill, J. Elks, D. Vignarajah, J. Lagopoulos, M. Min
Clinical Oncology.2021; 33(1): e1. CrossRef - Recommendations on Management of Locally Advanced Rectal Cancer During the COVID-19 Pandemic: an Iranian Consensus
Zahra Siavashpour, Farzad Taghizadeh-Hesary, Afshin Rakhsha
Journal of Gastrointestinal Cancer.2020; 51(3): 800. CrossRef - Recent advances in (chemo-)radiation therapy for rectal cancer: a comprehensive review
F. Roeder, E. Meldolesi, S. Gerum, V. Valentini, C. Rödel
Radiation Oncology.2020;[Epub] CrossRef - Predictive Significance of Mucinous Histology on Pathologic Complete Response Rate Following Capecitabine-Based Neoadjuvant Chemoradiation in Rectal Cancer: a Comparative Study
Sare Hosseini, NamPhong Nguyen, Mohammad Mohammadianpanah, Sepideh Mirzaei, Ali Mohammad Bananzadeh
Journal of Gastrointestinal Cancer.2019; 50(4): 716. CrossRef - A systematic review comparing radiation toxicity after various endorectal techniques
An-Sofie Verrijssen, Thirza Opbroek, Murillo Bellezzo, Gabriel P. Fonseca, Frank Verhaegen, Jean-Pierre Gerard, Arthur Sun Myint, Evert J. Van Limbergen, Maaike Berbee
Brachytherapy.2019; 18(1): 71. CrossRef - Is the Pathologic Response of T3 Rectal Cancer to High-Dose-Rate Endorectal Brachytherapy Comparable to External Beam Radiotherapy?
Richard Garfinkle, Sebastian Lachance, Te Vuong, Alexandre Mikhail, Vincent Pelsser, Adrian Gologan, Nancy A. Morin, Carol-Ann Vasilevsky, Marylise Boutros
Diseases of the Colon & Rectum.2019; 62(3): 294. CrossRef - Phase 2 Neoadjuvant Treatment Intensification Trials in Rectal Cancer: A Systematic Review
Mark T.W. Teo, Lucy McParland, Ane L. Appelt, David Sebag-Montefiore
International Journal of Radiation Oncology*Biology*Physics.2018; 100(1): 146. CrossRef - Colorectal Cancer Staging Using Three Clustering Methods Based on Preoperative Clinical Findings
Saeedeh Pourahmad, Soudabeh Pourhashemi, Mohammad Mohammadianpanah
Asian Pacific Journal of Cancer Prevention.2016; 17(2): 823. CrossRef - Lentivirus‐mediated shRNA interference of ghrelin receptor blocks proliferation in the colorectal cancer cells
An Liu, Chenggang Huang, Jia Xu, Xuehong Cai
Cancer Medicine.2016; 5(9): 2417. CrossRef - Is Low-Dose-Rate Endorectal Brachytherapy a New Treatment Method for Locally Advanced Distal Rectal Cancer?
Seung Hyuk Baik
Annals of Coloproctology.2015; 31(4): 115. CrossRef
- Intraoperative low-dose rate brachytherapy as an adjunct to surgery for marginally resectable rectal and recurrent anorectal carcinomas
- Preoperative Body Mass Index, 30-Day Postoperative Morbidity, Length of Stay and Quality of Life in Patients Undergoing Pelvic Exenteration Surgery for Recurrent and Locally-Advanced Rectal Cancer
- Jessica Beaton, Sharon Carey, Michael J Solomon, Ker-Kan Tan, Jane Young
- Ann Coloproctol. 2014;30(2):83-87. Published online April 25, 2014
- DOI: https://doi.org/10.3393/ac.2014.30.2.83
- 5,378 View
- 50 Download
- 20 Web of Science
- 22 Citations
-
Abstract
PDF
Purpose Malnutrition is associated with an increased risk of developing complications following gastrointestinal surgery, especially following radical surgeries such as pelvic exenteration. This study aims to determine if preoperative body mass index (BMI) is associated with 30-day morbidity, length of hospital stay and/or quality of life (QoL) in patients undergoing pelvic exenteration surgery for recurrent and locally-advanced rectal cancer prior to a prospective trial.
Methods A review of all patients who underwent pelvic exenteration surgery prior to 2008 was performed. Patients were included if they had a documented BMI as well as a QoL measurement (Functional Assessment Cancer Therapy - Colorectal questionnaire).
Results Thirty-one patients, with a mean age of 56 years, had preoperative height and weight data, as well as measures of postoperative QoL, and formed the study group. The numbers of patients with recurrent (n = 17) or locally-advanced rectal cancer (n = 14) were similar. The mean length of stay was 21 days while the mean BMI of the patients was 24.3 (± 5.9) kg/m2. The majority of the patients were either of normal weight (n = 15) or overweight/obese (n = 11). The average length of hospital stay was significantly longer in patients who were underweight compared to those who were of normal weight (F = 6.508, P = 0.006) and those who were overweight and obese (F = 6.508, P = 0.007).
Conclusion This study suggests that a lower body mass index preoperatively is associated with a longer length of hospital stay. BMI is not associated with long-term QoL in this patient group. However, further prospective research is required.
-
Citations
Citations to this article as recorded by- Prospective longitudinal trajectory of cancer survivorship among patients with recurrent rectal cancer: impact of treatment modalities and resection status
Tarik Sammour, Oliver Peacock, Brian K. Bednarski, Arvind Dasari, Prajnan Das, Benny Johnson, Grace L. Smith, George J. Chang, John Skibber, Y. Nancy You
Colorectal Disease.2025;[Epub] CrossRef - Living After Pelvic Exenteration: A Mixed-Methods Synthesis of Quality-of-Life Outcomes and Patient Perspectives
Vlad Rotaru, Elena Chitoran, Aisa Gelal, Giuseppe Gullo, Daniela-Cristina Stefan, Laurentiu Simion
Journal of Clinical Medicine.2025; 14(18): 6541. CrossRef - Defining Standard Data Reporting in Pelvic Exenteration Surgery for Rectal Cancer: A PelvEx Collaborative Review of Current Data Reporting
Cancers.2025; 17(17): 2764. CrossRef - Systematic Review of Patient-Reported Outcome Measures in Locally Recurrent Rectal Cancer
Niamh McKigney, Fergus Houston, Ellen Ross, Galina Velikova, Julia Brown, Deena Pravin Harji
Annals of Surgical Oncology.2023; 30(7): 3969. CrossRef - Prevention and management of complications in pelvic exenteration
Pia Persson, Peter Chong, Colin W Steele, Martha Quinn
European Journal of Surgical Oncology.2022; 48(11): 2277. CrossRef - Patient‐reported outcomes after pelvic exenteration for colorectal cancer: A systematic review
Andreas Denys, Yves van Nieuwenhove, Dirk Van de putte, Eva Pape, Piet Pattyn, Wim Ceelen, Gabriëlle H. van Ramshorst
Colorectal Disease.2022; 24(4): 353. CrossRef - Pelvic exenteration: Pre-, intra-, and post-operative considerations
Kheng-Seong Ng, Peter J.M. Lee
Surgical Oncology.2022; 43: 101787. CrossRef - Pelvic exenteration: Pre-, intra-, and post-operative considerations
Kheng-Seong Ng, Peter J.M. Lee
Surgical Oncology.2021; 37: 101546. CrossRef - Functional outcomes following pelvic exenteration: results from a prospective cohort study
Preet G. S. Makker, Cherry E. Koh, Michael J. Solomon, James Ratcliffe, Daniel Steffens
Colorectal Disease.2021; 23(10): 2647. CrossRef - Quality of life outcomes in patients undergoing surgery for locally recurrent rectal cancer
Tamara Glyn, Frank Frizelle
Seminars in Colon and Rectal Surgery.2020; 31(3): 100767. CrossRef - The obesity paradox in beyond total mesorectal excision surgery for locally advanced and recurrent rectal cancer
Daniel L. H. Baird, Constantinos Simillis, Gianluca Pellino, Christos Kontovounisios, Shahnawaz Rasheed, Paris P. Tekkis
Updates in Surgery.2019; 71(2): 313. CrossRef - The effect of preoperative nutritional status on postoperative complications and overall survival in patients undergoing pelvic exenteration: A multi-disciplinary, multi-institutional cohort study
N.J. Lyell, M. Kitano, B. Smith, A.L. Gleisner, F.J. Backes, G. Cheng, M.D. McCarter, S. Abdel-Misih, E.L. Jones
The American Journal of Surgery.2019; 218(2): 275. CrossRef - Preoperative Nutrition Status and Postoperative Outcomes in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Lauren Reece, Helen Dragicevich, Claire Lewis, Caila Rothwell, Oliver M. Fisher, Sharon Carey, Nayef A. Alzahrani, Winston Liauw, David L. Morris
Annals of Surgical Oncology.2019; 26(8): 2622. CrossRef - Factors affecting hospital length of stay following pelvic exenteration surgery
Ying Guo, Eugene Chang, Mehtap Bozkurt, Minjeong Park, Diane Liu, Jack B. Fu
Journal of Surgical Oncology.2018; 117(3): 529. CrossRef - Is BMI associated with post‐operative complication risk among patients undergoing major abdominal surgery for cancer? A systematic review
Tasha M. Hughes, Kejal Shah, Sabrena Noria, Timothy Pawlik
Journal of Surgical Oncology.2018; 117(5): 1009. CrossRef - A systematic review examining quality of life following pelvic exenteration for locally advanced and recurrent rectal cancer
E. Rausa, M. E. Kelly, L. Bonavina, P. R. O'Connell, D. C. Winter
Colorectal Disease.2017; 19(5): 430. CrossRef - The Evolution of Pelvic Exenteration Practice at a Single Center: Lessons Learned from over 500 Cases
Cherry E. Koh, Michael J. Solomon, Kilian G. Brown, Kirk Austin, Christopher M. Byrne, Peter Lee, Jane M. Young
Diseases of the Colon & Rectum.2017; 60(6): 627. CrossRef - Pelvic exenteration for advanced malignancy in elderly patients
R W Radwan, M D Evans, M Davies, D A Harris, J Beynon, O Hatcher, P Bose, M G Lucas, J Featherstone, U Khot, T V Chandrasekaran, N D Carr, S Gwynne, P Drew, M D Phan
Journal of British Surgery.2016; 103(2): e115. CrossRef - Systematic review of health-related quality of life in patients undergoing pelvic exenteration
D.P. Harji, B. Griffiths, G. Velikova, P.M. Sagar, J. Brown
European Journal of Surgical Oncology (EJSO).2016; 42(8): 1132. CrossRef - Exenteración pélvica total por cáncer primario del recto: resultados inmediatos y alejados
Guillermo Bannura, Alejandro Barrera, Carlos Melo, Felipe Illanes, Cristián Gallardo
Revista Chilena de Cirugía.2016; 68(3): 237. CrossRef - Translation from clinical trials to routine practice: How to demonstrate community benefit
David Roder, Elizabeth Buckley
Asia-Pacific Journal of Clinical Oncology.2015; 11(1): 1. CrossRef - Preoperative Body Mass Index and Postoperative Complications After Pelvic Exenteration in Recurrent or Locally Advanced Rectal Cancer Patients
Moo-Jun Baek
Annals of Coloproctology.2014; 30(2): 60. CrossRef
- Prospective longitudinal trajectory of cancer survivorship among patients with recurrent rectal cancer: impact of treatment modalities and resection status
- Managing Deep Postanal Space Sepsis via an Intersphincteric Approach: Our Early Experience
- Ker-Kan Tan, Dean C. Koh, Charles B. Tsang
- Ann Coloproctol. 2013;29(2):55-59. Published online April 30, 2013
- DOI: https://doi.org/10.3393/ac.2013.29.2.55
- 4,948 View
- 79 Download
- 15 Citations
-
Abstract
PDF
Purpose Managing deep postanal (DPA) sepsis often involves multiple procedures over a long time. An intersphincteric approach allows adequate drainage to be performed while tackling the primary pathology at the same sitting. The aim of our study was to evaluate this novel technique in managing DPA sepsis.
Methods A retrospective review of all patients who underwent this intersphincteric technique in managing DPA sepsis from February 2008 to October 2010 was performed. All surgeries were performed by the same surgeon.
Results Seventeen patients with a median age of 43 years (range, 32 to 71 years) and comprised of 94.1% (n = 16) males formed the study group. In all patients, an internal opening in the posterior midline with a tract leading to the deep postanal space was identified. This intersphincteric approach operation was adopted as the primary procedure in 12 patients (70.6%) and was successful in 11 (91.7%). In the only failure, the sepsis recurred, and a successful advancement flap procedure was eventually performed. Five other patients (29.4%) underwent this same procedure as a secondary procedure after an initial drainage operation. Only one was successful. In the remaining four patients, one had a recurrent abscess that required drainage while the other three patients had a tract between the internal opening and the intersphincteric incision. They subsequently underwent a drainage procedure with seton insertion and advancement flap procedures.
Conclusion Managing DPA space sepsis via an intersphincteric approach is successful in 70.6% of patients. This single-staged technique allows for effective drainage of the sepsis and removal of the primary pathology in the intersphincteric space.
-
Citations
Citations to this article as recorded by- Deep Postanal Abscess With Sacrococcygeal Osteomyelitis: A Case Report
Javid Ahmadov, Mustafa Anil Turhan, Ender Erguder, Sezai Leventoğlu, Bulent Mentes
Cureus.2025;[Epub] CrossRef - Is Primary Opening of Fistula-in-Ano Always at Dentate Line: Correlation Between MRI and Operative Findings in 379 Patients
Pankaj Garg, Gabriele Naldini, Vincent De Parades, Petr Tsarkov, Vipul Yagnik, Kaushik Bhattacharya, Baljit Kaur, G Mahak
Clinical and Experimental Gastroenterology.2025; Volume 18: 121. CrossRef - Process to determine the level of the primary internal opening of anal fistula on magnetic resonance imaging
Pankaj Garg, Baljit Kaur, G. Mahak
Annals of Coloproctology.2025; 41(3): 253. CrossRef - Anorectal Abscess
Anna Kata, Jonathan S. Abelson
Clinics in Colon and Rectal Surgery.2024; 37(06): 368. CrossRef - Research Progress on Diagnosis and Surgical Treatment of Perianal Deep Space Abscess
永罡 秦
Advances in Clinical Medicine.2023; 13(01): 180. CrossRef - A Rare Case of Posterior Horseshoe Abscess Extending to Anterolateral Extraperitoneal Compartment: Anatomical and Technical Considerations
Christianna Oikonomou, Periklis Alepas, Stelios Gavriil, Dimitrios Kalliouris, Konstantinos Manesis, Petros Bouboulis, Dimitrios Filippou, Panagiotis Skandalakis
Annals of Coloproctology.2019; 35(4): 216. CrossRef - Klinische Anatomie der Anorektalregion in Bezug auf das Analfistelleiden
S. Stelzner, T. Wedel
coloproctology.2019; 41(6): 390. CrossRef - Understanding and Treating Supralevator Fistula-in-Ano: MRI Analysis of 51 Cases and a Review of Literature
Pankaj Garg
Diseases of the Colon & Rectum.2018; 61(5): 612. CrossRef - The treatment of anal fistula: secondACPGBIPosition Statement – 2018
G. Williams, A. Williams, P. Tozer, R. Phillips, A. Ahmad, D. Jayne, C. Maxwell‐Armstrong
Colorectal Disease.2018; 20(S3): 5. CrossRef - Transanal opening of intersphincteric space (TROPIS) - A new procedure to treat high complex anal fistula
Pankaj Garg
International Journal of Surgery.2017; 40: 130. CrossRef - Clinical Significance of 2 Deep Posterior Perianal Spaces to Complex Cryptoglandular Fistulas
Heng Zhang, Zhi-yang Zhou, Bang Hu, De-chao Liu, Hui Peng, Shang-kui Xie, Dan Su, Dong-lin Ren
Diseases of the Colon & Rectum.2016; 59(8): 766. CrossRef - Complex Fistula-In-Ano
J. Graham Williams
Diseases of the Colon & Rectum.2016; 59(8): 707. CrossRef - S3-Leitlinie: Analabszess
A. Ommer, A. Herold, E. Berg, St. Farke, A. Fürst, F. Hetzer, A. Köhler, S. Post, R. Ruppert, M. Sailer, T. Schiedeck, O. Schwandner, B. Strittmatter, B. H. Lenhard, W. Bader, S. Krege, H. Krammer, E. Stange
coloproctology.2016; 38(6): 378. CrossRef - Behandlung kryptoglandulärer, supralevatorischer Abszesse im MRT-Zeitalter: eine Fallserie
A. Furtwängler
coloproctology.2015; 37(3): 214. CrossRef - Modern management of deep post-anal space abscess and horseshoe fistulas
Reuben D. Shin, Jason F. Hall
Seminars in Colon and Rectal Surgery.2014; 25(4): 210. CrossRef
- Deep Postanal Abscess With Sacrococcygeal Osteomyelitis: A Case Report
- Transanal Endoscopic Microsurgery for the Treatment of Well-Differentiated Rectal Neuroendocrine Tumors
- Hyoung Ran Kim, Woo Yong Lee, Kyung Uk Jung, Hyuk Jun Chung, Chul Joong Kim, Hae-Ran Yun, Yong Beom Cho, Seong Hyeon Yun, Hee Cheol Kim, Ho-Kyung Chun
- J Korean Soc Coloproctol. 2012;28(4):201-204. Published online August 31, 2012
- DOI: https://doi.org/10.3393/jksc.2012.28.4.201
- 6,169 View
- 35 Download
- 10 Citations
-
Abstract
PDF
Purpose Recently, an increase in well-differentiated rectal neuroendocrine tumors (WRNETs) has been noted. We aimed to evaluate transanal endoscopic microsurgery (TEM) for the treatment of WRNETs.
Methods Between December 1995 and August 2009, 109 patients with WRNETs underwent TEM. TEM was performed for patients with tumors sizes of up to 20 mm and without a lymphadenopathy. These patients had been referred from other clinics after having been diagnosed with WRNETs by using a colonoscopic biopsy; they had undergone a failed endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR) and exhibited an involved resection margin and remaining tumor after ESD or EMR, regardless of the distance from the anal verge. This study included 38 patients that had more than three years of follow-up.
Results The mean age of the patients was 51.3 ± 11.9 years, the mean tumor size was 8.0 ± 3.9 mm, and no morbidity occurred. Thirty-five patients were asymptomatic. TEM was performed after a colonoscopic resection in 13 cases because of a positive resection margin, a residual tumor or a non-lifting lesion. Complete resections were performed in 37 patients; one patient with a positive margin was considered surgically complete. In one patient, liver metastasis and a recurrent mesorectal node occurred after five and 10 years, respectively.
Conclusion TEM might provide an accessible and effective treatment either as an initial or as an adjunct after a colonoscopic resection for a WRNET.
-
Citations
Citations to this article as recorded by- Transanal endoscopic microsurgery in the treatment of rectal neuroendocrine tumors: a retrospective 10-year single-center experience
Marek Szczepkowski, Piotr Witkowski, Alicja Przywózka-Suwała, Karolina Skonieczna-Żydecka, Teresa Starzyńska, Krzysztof Dąbkowski
Langenbeck's Archives of Surgery.2025;[Epub] CrossRef - Endoscopic Submucosal Dissection and Transanal Endoscopic Microsurgery in the Treatment of Rectal Neuroendocrine Tumors: Systematic Review and Meta-Analysis of the Observational Studies
Krzysztof Dąbkowski, Karolina Skonieczna-Żydecka, Katarzyna Gaweł, Wojciech Marlicz, Piotr Szredzki, Andrzej Białek
Clinical and Translational Gastroenterology.2025;[Epub] CrossRef - Oncological outcomes according to the treatment modality based on the size of rectal neuroendocrine tumors: a single-center retrospective study
Jimin Son, In Ja Park, Dong-Hoon Yang, Jisup Kim, Kyoung-Jo Kim, Jeong-Sik Byeon, Seung Mo Hong, Young Il Kim, Jong Beom Kim, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
Surgical Endoscopy.2022; 36(4): 2445. CrossRef - Long-term outcomes of transanal endoscopic microsurgery for the treatment of rectal neuroendocrine tumors
Wei-Kun Shi, Rui Hou, Yun-Hao Li, Xiao-Yuan Qiu, Yu-Xin Liu, Bin Wu, Yi Xiao, Jiao-Lin Zhou, Guo-Le Lin
BMC Surgery.2022;[Epub] CrossRef - Non-conventional applications for transanal endoscopic microsurgery. A single center experience and a systematic review of literature
Rosita DE VINCENTI, Fabio CIANCHI, Francesco CORATTI
Minerva Surgery.2022;[Epub] CrossRef - Transanalis műtéti útmutató – második kiadás
Kálmán Almási, Szabolcs Ábrahám, József Baracs, Attila Bursics, Zoltán Jánó, Tamás Sztipits, Áron Szűts, Dezső Tóth, Attila Zaránd, Balázs Bánky
Orvosi Hetilap.2022; 163(Supplement): 3. CrossRef - Endoscopic submucosal dissection versus transanal local excision for rectal carcinoid: a comparative study
Fei-hu Yan, Zheng Lou, Shi-jie Hu, Xiao-dong Xu, Hao Wang, Han-tao Wang, Rong-gui Meng, Chuan-gang Fu, Wei Zhang, Jian He, En-da Yu
World Journal of Surgical Oncology.2016;[Epub] CrossRef - Efficacy and Safety of Endoscopic Resection Therapies for Rectal Carcinoid Tumors: A Meta-Analysis
Lei He, Tao Deng, Hesheng Luo
Yonsei Medical Journal.2015; 56(1): 72. CrossRef - Full-thickness excision using transanal endoscopic microsurgery for treatment of rectal neuroendocrine tumors
Wei-Jie Chen
World Journal of Gastroenterology.2015; 21(30): 9142. CrossRef - Current Issues Involving the Treatment of Small Rectal Carcinoid Tumors
Dae Kyung Sohn
Journal of the Korean Society of Coloproctology.2012; 28(4): 176. CrossRef
- Transanal endoscopic microsurgery in the treatment of rectal neuroendocrine tumors: a retrospective 10-year single-center experience
Review
- Optimal Treatment of Symptomatic Hemorrhoids
- Seok-Gyu Song, Soung-Ho Kim
- J Korean Soc Coloproctol. 2011;27(6):277-281. Published online December 31, 2011
- DOI: https://doi.org/10.3393/jksc.2011.27.6.277
- 23,817 View
- 167 Download
- 22 Citations
-
Abstract
PDF
Hemorrhoids are the most common anorectal complaint, and approximately 10 to 20 percent of patients with symptomatic hemorrhoids require surgery. Symptoms of hemorrhoids, such as painless rectal bleeding, tissue protrusion and mucous discharge, vary. The traditional therapeutic strategies of medicine include surgical, as well as non-surgical, treatment. To alleviate symptoms caused by hemorrhoids, oral treatments, such as fiber, suppositories and Sitz baths have been applied to patients. Other non-surgical treatments, such as infrared photocoagulation, injection sclerotherapy and rubber band ligation have been used to fixate the hemorrhoid's cushion. If non-surgical treatment has no effect, surgical treatments, such as a hemorrhoidectomy, procedure for prolapsed hemorrhoids, and transanal hemorrhoidal dearterialization are used.
-
Citations
Citations to this article as recorded by- Real-World Outcomes of Hemorrhoidectomy With and Without Advanced Energy Devices: A Propensity Score-Matched Analysis From a Tertiary Center
I-Chun Huang, Hsin Hsu, Jayson Enn Ming Wong, Kun-Yu Tsai, Shu-Huan Huang
Current Problems in Surgery.2026; : 101981. CrossRef - Comparative analysis of Ferguson hemorrhoidectomy combined with doppler-guided hemorrhoidal artery ligation and Ferguson hemorrhoidectomy in hemorrhoidal disease treatment
Ismail Cem Eray, Ugur Topal, Serdar Gumus, Kubilay Isiker, Burak Yavuz, Ishak Aydin
World Journal of Gastrointestinal Surgery.2025;[Epub] CrossRef - HEMORRHOIDS: A COMPREHENSIVE REVIEW OF ETIOLOGY, PATHOPHYSIOLOGY, RISK FACTOR AND TREATMENT OPTION
YADAV AKASH RAMNAYAN, JIMISHA KHER, SNIGDHA DAS MANDAL
Innovare Journal of Medical Sciences.2025; : 1. CrossRef - Outcomes of embolization therapy of superior rectal arteries for the management of grade 1 to 3 internal hemorrhoids: a systematic Review of clinical studies
Mustafa Al Jnainati, Niharika Ikkurthy, Mohammad Ayoub, Areeba Shahid, Mirza Taha Baig, Muhammad Iltaf, Jana Al Jnainati
International Journal of Colorectal Disease.2025;[Epub] CrossRef - A Hospital-Based Longitudinal Study of Rubber Band Ligation and Sclerotherapy Treatment for Internal Hemorrhoids From South India
Samrobinson J, Jeyaganesh R, Geetha Arumugam, Nawin J Vignesh
Cureus.2024;[Epub] CrossRef - A comparative study of rubber band ligation versus BANANA-Clip in grade 1 to 3 internal hemorrhoids
Dong Wan Kang, Byoung Soo Kim, Ji Hun Kim, Kyong Rae Kim, Gyong Suk Kang
Annals of Coloproctology.2023; 39(1): 41. CrossRef - Treatment of haemorrhoids: rubber band ligation or sclerotherapy (THROS)? Study protocol for a multicentre, non-inferiority, randomised controlled trial
J. Y. van Oostendorp, T. C. Sluckin, I. J. M. Han-Geurts, S. van Dieren, R. Schouten
Trials.2023;[Epub] CrossRef - Finding Molecular Inhibitors of the Inflammatory Pathway in the Large Intestine Along with Molecular Dynamics with Emphasis on the Use of TCM Database
Ali Sargazi, Baratali Fakheri, Abbas Ali Bahari, Nafiseh Mahdinezhad
Gene, Cell and Tissue.2023;[Epub] CrossRef - Possibile ruolo della terapia nutraceutica nel trattamento medico della malattia emorroidaria
Claudio TOSCANA, Leonardo GALLI, Edoardo TOSCANA, Laura BALDINI, Gabriella GIARRATANO, Maria VADALÀ, Beniamino PALMIERI
Gazzetta Medica Italiana Archivio per le Scienze Mediche.2023;[Epub] CrossRef - Hybrid methods treatments for III and IV grade hemorrhoids
E. A. Zagriadskiǐ
Koloproktologia.2023; 22(4): 53. CrossRef - Risk factors for hemorrhoidal disease among healthy young and middle-aged Korean adults
Yun Soo Hong, Kyung Uk Jung, Sanjay Rampal, Di Zhao, Eliseo Guallar, Seungho Ryu, Yoosoo Chang, Hyung Ook Kim, Hungdai Kim, Ho-Kyung Chun, Chong Il Sohn, Hocheol Shin, Juhee Cho
Scientific Reports.2022;[Epub] CrossRef - Doppler-guided hemorrhoidal dearterialization. Technical evolution and results of treatment (review)
E. A. Zagriadskiǐ, V. S. Tolstyh
Koloproktologia.2021; 20(1): 87. CrossRef - Treatment for Hemorrhoids: Conservative Treatment and Office-based Treatments
Tsutomu Masuda, Naoki Inatsugi, Shusaku Yoshikawa, Seiji Terauchi, Hideki Uchida, Takeshi Nakao, Kentaro Yamaoka, Mizumi Inagaki, Takashi Yokoo, Kohei Okamoto
Nihon Daicho Komonbyo Gakkai Zasshi.2021; 74(10): 521. CrossRef - Comparative Study of Postoperative Complications after Rubber Band Ligation (RBL) and RBL Combined with Sclerotherapy in Treatment of Second- and Third-Degree Internal Hemorrhoids
Zhixian Liu, Xianqing Song, Feng Ye
Indian Journal of Surgery.2020; 82(3): 345. CrossRef - THE CHOICE OF TREATMENT IN PATIENTS WITH HEMORRHOIDAL DISEASE (THE RESULTS OF THE OBSERVATIONAL PROGRAM RE-VISION)
E. A. Zagriadskiy, A. M. Bogomazov, E. В. Golovko
Koloproktologia.2019; 18(4): 100. CrossRef - Postoperative Pain as a Decision-Making Tool in Treating Hemorrhoids on an In- or Out-Patient Basis After Stapled Mucosectomy (Longo Procedure)
D. Kovacevic, G. Gubler, M. Turina, M. K. Muller, A. Nocito, N. Attigah, M. Weber
International Surgery.2019; 104(9-10): 461. CrossRef - Transanal Hemorrhoidal Dearterialization Versus Stapled Hemorrhoidopexy: Long-Term Follow-up of a Prospective Randomized Study
Gabriella Giarratano, Edoardo Toscana, Claudio Toscana, Giuseppe Petrella, Mostafa Shalaby, Pierpaolo Sileri
Surgical Innovation.2018; 25(3): 236. CrossRef - Conservative Treatment of Hemorrhoids: Results of an Observational Multicenter Study
Evgeny A. Zagriadskiĭ, Alexey M. Bogomazov, Evgeny B. Golovko
Advances in Therapy.2018; 35(11): 1979. CrossRef - CONSERVATIVE TREATMENT OF HEMORRHOIDS. AN ALTERNATIVE TO SURGICAL METHODS OR COMPONENTS? CHORUS PROGRAM RESULTS
E. A. Zagryadskiy, A. M. Bogomazov, E. B. Golovko
Koloproktologia.2018; (1): 27. CrossRef - Haemorrhoids are associated with internal iliac vein reflux in up to one-third of women presenting with varicose veins associated with pelvic vein reflux
JM Holdstock, SJ Dos Santos, CC Harrison, BA Price, MS Whiteley
Phlebology: The Journal of Venous Disease.2015; 30(2): 133. CrossRef - A prospective, randomized, three arm, open label study comparing the safety and efficacy of PP110, a novel treatment for hemorrhoids to preparation-H® maximum strength cream in the treatment of grade 2–3 hemorrhoids
Ehud Klein, Ron Shapiro, Jose Ben-Dahan, Moshe Simcha, Yosef Azuri, Ada Rosen
Molecular and Cellular Therapies.2015;[Epub] CrossRef - Recombinant streptokinasevshydrocortisone suppositories in acute hemorrhoids: A randomized controlled trial
Francisco Hernández-Bernal, Georgina Castellanos-Sierra, Carmen M Valenzuela-Silva, Karem M Catasús-Álvarez, Osmany Martínez-Serrano, Odalys C Lazo-Diago, Cimara H Bermúdez-Badell, José R Causa-García, Juan E Domínguez-Suárez
World Journal of Gastroenterology.2015; 21(23): 7305. CrossRef
- Real-World Outcomes of Hemorrhoidectomy With and Without Advanced Energy Devices: A Propensity Score-Matched Analysis From a Tertiary Center
Original Article
- Surgical Outcomes after Total Colectomy with Ileorectal Anastomosis in Patients with Medically Intractable Slow Transit Constipation
- Guiyun Sohn, Chang Sik Yu, Chan Wook Kim, Jae Young Kwak, Tae Young Jang, Kyung Ho Kim, Song Soo Yang, Yong Sik Yoon, Seok-Byung Lim, Jin Cheon Kim
- J Korean Soc Coloproctol. 2011;27(4):180-187. Published online August 31, 2011
- DOI: https://doi.org/10.3393/jksc.2011.27.4.180
- 14,758 View
- 86 Download
- 33 Citations
-
Abstract
PDF
Purpose The aim of this study was to evaluate outcomes of a total colectomy with ileorectal anastomosis in patients with slow transit constipation.
Methods A retrospective review of 37 consecutive patients with slow transit constipation who underwent a total colectomy between 1994 and 2008 was undertaken. Preoperative and postoperative Wexner's constipation scores were collected and used to evaluate the outcomes after surgical treatment. Also patients' postoperative satisfaction scores were collected using a 4-point scale.
Results The 37 patients consisted of 31 women and 6 men, with a median age of 41 years (range, 17 to 71 years). Pre- and post-operative Wexner's scores were collected from 33 patients (89.1%), and the mean preoperative Wexner's score was 19.3 (range, 11 to 24), which decreased to an average post-operative score of 2.3 (range, 0 to 8). Neither intraoperative complications nor postoperative mortalities were noted. Five patients (13.5%) had early postoperative complications, and the most common complication was postoperative ileus (10.8%). Seven patients (18.9%) had late postoperative complications, and postoperative ileus (10.8%) was also the most common. Twenty seven of 33 patients were satisfied with their surgical outcome (81.8%).
Conclusion A total colectomy with ileorectal anastomosis might be an effective surgical procedure with acceptable morbidity to treat medically intractable slow transit constipation.
-
Citations
Citations to this article as recorded by- Rehabilitation for Chronic Constipation: Integrative Approaches to Diagnosis and Treatment
Luana Alexandrescu, Ionut Eduard Iordache, Alina Mihaela Stanigut, Laura Maria Condur, Doina Ecaterina Tofolean, Razvan Catalin Popescu, Andreea Nelson Twakor, Eugen Dumitru, Andrei Dumitru, Cristina Tocia, Alexandra Herlo, Ionut Tiberiu Tofolean
Gastrointestinal Disorders.2025; 7(1): 11. CrossRef - Surgery for chronic idiopathic constipation: pediatric and adult patients – a systematic review
Kerry A. Swanson, Hannah M. Phelps, William C. Chapman, Sean C. Glasgow, Radhika K. Smith, Shannon Joerger, Elizabeth C. Utterson, Baddr A. Shakhsheer
Journal of Gastrointestinal Surgery.2024; 28(2): 170. CrossRef - Ileorectal intussusception compared to end-to-end ileorectal anastomosis after laparoscopic total colectomy in slow-transit constipation
Hong Zhi Geng, Chen Xu, Yongjun Yu, Jiying Cong, Zhao Zhang, Yuwei Li, Qilong Chen
Current Problems in Surgery.2024; 61(6): 101471. CrossRef - A systematic review of outcomes and quality of life after ileorectal anastomosis for ulcerative colitis
Mohammed Al-Rashedy, Tanmoy Mukherjee, Alan Askari, Shashank Gurjar
Arab Journal of Gastroenterology.2023; 24(2): 79. CrossRef - Laparoscopic total colectomy with ileorectal anastomosis and subtotal colectomy with antiperistaltic cecorectal anastomosis for slow transit constipation
Xiu-Mei Deng, Tian-Yu Zhu, Guo-Jun Wang, Bu-Lang Gao, Rui-Xin Li, Jing-Tao Wang
Updates in Surgery.2023; 75(4): 871. CrossRef - Single-incision clipless laparoscopic total colectomy for intractable slow transit constipation: a single surgeon’s experience
Hidejiro Kawahara, Nobuo Omura
Langenbeck's Archives of Surgery.2022; 407(6): 2585. CrossRef - Idiopathic Megacolon—Short Review
Adrian Constantin, Florin Achim, Dan Spinu, Bogdan Socea, Dragos Predescu
Diagnostics.2021; 11(11): 2112. CrossRef - Heterogeneous outcome reporting in adult slow‐transit constipation studies: Systematic review towards a core outcome set
Stella C M Heemskerk, Adriënne H Rotteveel, Jarno Melenhorst, Stéphanie O Breukink, Merel L Kimman, Carmen D Dirksen
Journal of Gastroenterology and Hepatology.2020; 35(2): 192. CrossRef - Defecation function and quality of life in patients with slow-transit constipation after colectomy
Yue Tian, Li Wang, Jing-Wang Ye, Yong Zhang, Hui-Chao Zheng, Hao-De Shen, Fan Li, Bao-Hua Liu, Wei-Dong Tong
World Journal of Clinical Cases.2020; 8(10): 1897. CrossRef - Laparoscopic subtotal colectomy in the surgical treatment of chronic constipation in patients with dolichocolon
V.V. Anischenko, D.A. Kim
Endoskopicheskaya khirurgiya.2020; 26(6): 12. CrossRef - Concurrent total abdominal colectomy and ileorectal anastomosis with transvaginal posterior colporrhaphy for constipation
Peter Chia Yeh, Francisco Orejuela, Lisa Haubert
International Urogynecology Journal.2019; 30(3): 501. CrossRef - Percutaneous endoscopic colostomy for adults with chronic constipation: Retrospective case series of 12 patients
D. Strijbos, D. Keszthelyi, A. A. M. Masclee, L. P. L. Gilissen
Neurogastroenterology & Motility.2018;[Epub] CrossRef - Searching for a definition for pharmacologically refractory constipation: A systematic review
Alex Yu Sen Soh, Jin‐Yong Kang, Kewin Tien Ho Siah, Carmelo Scarpignato, Kok‐Ann Gwee
Journal of Gastroenterology and Hepatology.2018; 33(3): 564. CrossRef - Patient-Reported Outcome After Ostomy Surgery for Chronic Constipation
Fareed Iqbal, Valerie van der Ploeg, Franklin Adaba, Alan Askari, Jamie Murphy, R. John Nicholls, Carolynne Vaizey
Journal of Wound, Ostomy & Continence Nursing.2018; 45(4): 319. CrossRef - Surgery for constipation: systematic review and practice recommendations
C. H. Knowles, U. Grossi, M. Chapman, J. Mason
Colorectal Disease.2017; 19(S3): 17. CrossRef - Colonic Inertia: approach and treatment
Ana Sofia Garcês Ferreira Soares, Laura Elisabete Ribeiro Barbosa
Journal of Coloproctology.2017; 37(01): 063. CrossRef - Bioengineering the gut: future prospects of regenerative medicine
Khalil N. Bitar, Elie Zakhem
Nature Reviews Gastroenterology & Hepatology.2016; 13(9): 543. CrossRef - Surgical management of severe constipation due to slow transit and obstructed defecation syndrome
Venetia Giannakaki, Liliana Bordeianou
Seminars in Colon and Rectal Surgery.2016; 27(1): 28. CrossRef - Evaluating the safety and the effects on colonic compliance of neostigmine during motility testing in patients with chronic constipation
M. A. Mouchli, M. Camilleri, T. Lee, G. Parthasarathy, P. Vijayvargiya, M. Halland, A. Acosta, A. E. Bharucha
Neurogastroenterology & Motility.2016; 28(6): 871. CrossRef - Comparison of laparoscopic subtotal colectomy with posterior vaginal suspension and laparoscopic subtotal colectomy with transvaginal repair for patients with slow-transit constipation complicated with rectocele: a non-randomized comparative study in a si
Si Yu, Jian-zhong Deng, Xiang Peng, Yong-hui Zhou, Long-qing Cheng, Yi-ban Lin, Jia-cheng Zhu, Te-dong Luo
Surgical Endoscopy.2016; 30(7): 2759. CrossRef - Results of long-term retrograde rectal cleansing in patients with constipation or fecal incontinence
P. F. Vollebregt, A. K. E. Elfrink, W. J. H. J. Meijerink, R. J. F. Felt-Bersma
Techniques in Coloproctology.2016; 20(9): 633. CrossRef - Clinical Features and Colonic Motor Disturbances in Chronic Megacolon in Adults
Ralph Hurley O’Dwyer, Andrés Acosta, Michael Camilleri, Duane Burton, Irene Busciglio, Adil E. Bharucha
Digestive Diseases and Sciences.2015; 60(8): 2398. CrossRef - Chronic severe constipation
Nikolaos P. Andromanakos, Stamatis I. Pinis, Alkiviadis I. Kostakis
European Journal of Gastroenterology & Hepatology.2015; 27(3): 204. CrossRef - Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total Colectomy
Patrick Schoeters, Karl De Pooter
Case Reports in Gastrointestinal Medicine.2015; 2015: 1. CrossRef - Molecular and Cellular Characteristics of the Colonic Pseudo-obstruction in Patients With Intractable Constipation
Yoon Suh Do, Seung-Jae Myung, Sun-Young Kwak, Soohan Cho, Enoch Lee, Min Jeong Song, Chang Sik Yu, Yong Sik Yoon, Hye Kyung Lee
Journal of Neurogastroenterology and Motility.2015; 21(4): 560. CrossRef - Effect of Different Surgical Options on Curative Effect, Nutrition, and Health Status of Patients with Slow Transit Constipation
Fan Li, Tao Fu, Weidong Tong, Anping Zhang, Chunxue Li, Yu Gao, Jin Song Wu, Baohua Liu
International Journal of Colorectal Disease.2014; 29(12): 1551. CrossRef - A modified total colonic exclusion for elderly patients with severe slow transit constipation
Q. Qian, C. Jiang, Y. Chen, Z. Ding, Y. Wu, K. Zheng, Q. Qin, Z. Liu
Techniques in Coloproctology.2014; 18(7): 629. CrossRef - Management of Chronic Intractable Constipation in Children
Basavaraj Kerur, Kanchan Kantekure, Silvana Bonilla, Bruce Orkin, Alejandro F. Flores
Journal of Pediatric Gastroenterology and Nutrition.2014; 59(6): 754. CrossRef - Comparison of hand‐assisted laparoscopy with open total colectomy for slow transit constipation: A retrospective study
Qin Song Sheng, Jian Jiang Lin, Wen Bin Chen, Fan Long Liu, Xiang Ming Xu, Han Ju Hua, Cai Zhao Lin, Jin Hai Wang
Journal of Digestive Diseases.2014; 15(8): 419. CrossRef - The role of hand-assisted laparoscopic surgery in total colectomy for colonic inertia: a retrospective study
Dan Yang Wang, Jian Jiang Lin, Xiang Ming Xu, Fan Long Liu
Journal of the Korean Surgical Society.2013; 85(3): 123. CrossRef - The use of prucalopride in real life for the treatment of constipation subtypes: ups and downs
G. Bassotti, M. Bellini
Techniques in Coloproctology.2013; 17(5): 475. CrossRef - Colectomy with ileorectal anastomosis has a worse 30‐day outcome when performed for colonic inertia than for a neoplastic indication
A. Reshef, B. Gurland, M. Zutshi, R. P. Kiran, T. Hull
Colorectal Disease.2013; 15(4): 481. CrossRef - Long-term Follow-up of the Jinling Procedure for Combined Slow-Transit Constipation and Obstructive Defecation
Ning Li, Jun Jiang, Xiaobo Feng, Weiwei Ding, Jianlei Liu, Jieshou Li
Diseases of the Colon & Rectum.2013; 56(1): 103. CrossRef
- Rehabilitation for Chronic Constipation: Integrative Approaches to Diagnosis and Treatment
Case Report
- Efficacy of Imatinib Mesylate Neoadjuvant Treatment for a Locally Advanced Rectal Gastrointestinal Stromal Tumor
- Kyu Jong Yoon, Nam Kyu Kim, Kang Young Lee, Byung Soh Min, Hyuk Hur, Jeonghyun Kang, Sarah Lee
- J Korean Soc Coloproctol. 2011;27(3):147-152. Published online June 30, 2011
- DOI: https://doi.org/10.3393/jksc.2011.27.3.147
- 5,684 View
- 37 Download
- 10 Citations
-
Abstract
PDF
Surgery is the standard treatment for a primary gastrointestinal stromal tumor (GIST); however, surgical resection is often not curative, particularly for large GISTs. In the past decade, with imatinib mesylate (IM), management strategies for GISTs have evolved significantly, and now IM is the standard care for patients with locally advanced, recurrent or metastatic GISTs. Adjuvant therapy with imatinib was recently approved for use, and preoperative imatinib is an emerging treatment option for patients who require cytoreductive therapy. IM neoadjuvant therapy for primary GISTs has been reported, but there is no consensus on the dose of the drug, the duration of treatment and the optimal time of surgery. These are critical because drug resistance or tumor progression can develop with a prolonged treatment. This report describes two cases of large rectal malignant GISTs, for which a abdominoperineal resection was initially anticipated. The two patients received IM preoperative treatment; we followed-up with CT or magnetic resonance imaging to access the response. After 9 months of treatment, a multi-disciplinary consensus that maximal benefit from imatinib had been achieved was reached. We determined the best time for surgical intervention and successfully performed sphincter-preserving surgery before resistance to imatinib or tumor progression occurred. We believe that a multidisciplinary team approach, considerating the optimal duration of therapy and the timing of surgery, is required to optimize treatment outcome.
-
Citations
Citations to this article as recorded by- Safety, effectiveness and the optimal duration of preoperative imatinib in locally advanced gastric gastrointestinal stromal tumors: A retrospective cohort study
Xiangfei Sun, Xiaohan Lin, Qiang Zhang, Chao Li, Ping Shu, Xiaodong Gao, Kuntang Shen
Cancer Medicine.2024;[Epub] CrossRef - Clinicopathological and Immunohistochemical Characterization of Gastrointestinal Stromal Tumour at Four Tertiary Health Centers in Nigeria Using CD117, DOG1, and Human Epidermal Growth Factor Receptor-2 Biomarkers
Mumini Wemimo Rasheed, Afolayan Enoch Abiodun, Uchechukwu Brian Eziagu, Najeem Adedamola Idowu, Abdullahi Kabiru, Taiwo Adeyemi Adegboye, Waheed Akanni Oluogun, Adekunle Adebayo Ayoade
Annals of African Medicine.2023; 22(4): 501. CrossRef - Open transanal resection of low rectal stromal tumor following neoadjuvant therapy of imatinib mesylate: Report of 11 cases and review of literature
Qiang Sun, Ning Su, Xinxing Li, Zhiqian Hu, Weijun Wang
Asia-Pacific Journal of Clinical Oncology.2020; 16(3): 123. CrossRef - Using endoscopy to minimize the extent of resection in the management of giant GISTs of the stomach
Hishaam Ismael, Yury Ragoza, Steven Cox
International Journal of Surgery Case Reports.2017; 36: 26. CrossRef - Combined Therapy of Gastrointestinal Stromal Tumors
Piotr Rutkowski, Daphne Hompes
Surgical Oncology Clinics of North America.2016; 25(4): 735. CrossRef - Indications for surgery in advanced/metastatic GIST
Samuel J. Ford, Alessandro Gronchi
European Journal of Cancer.2016; 63: 154. CrossRef - Surgical treatment of gastrointestinal stromal tumour of the rectum in the era of imatinib
M J Wilkinson, J E F Fitzgerald, D C Strauss, A J Hayes, J M Thomas, C Messiou, C Fisher, C Benson, P P Tekkis, I Judson
British Journal of Surgery.2015; 102(8): 965. CrossRef - Intolerance to Imatinib in Gastrointestinal Stromal Tumors: A Case Report and a Review of Literature
Yousra Akasbi, Samia Arifi, Sami Aziz Brahmi, Fatima Zahra El Mrabet, Nawfel Mellas, Fatima Zahra Mernisi, Omar El Mesbahi
Journal of Gastrointestinal Cancer.2014; 45(S1): 71. CrossRef - Primary localized rectal/pararectal gastrointestinal stromal tumors: results of surgical and multimodal therapy from the French Sarcoma group
Thanh-Khoa Huynh, Pierre Meeus, Philippe Cassier, Olivier Bouché, Sophie Lardière-Deguelte, Antoine Adenis, Thierry André, Julien Mancini, Olivier Collard, Michael Montemurro, Emmanuelle Bompas, Maria Rios, Nicolas Isambert, Didier Cupissol, Jean-Yves Bla
BMC Cancer.2014;[Epub] CrossRef - Neoadjuvant Imatinib in Locally Advanced Gastrointestinal Stromal Tumors (GIST): The EORTC STBSG Experience
Piotr Rutkowski, Alessandro Gronchi, Peter Hohenberger, Sylvie Bonvalot, Patrick Schöffski, Sebastian Bauer, Elena Fumagalli, Pawel Nyckowski, Buu-Phuc Nguyen, Jan Martijn Kerst, Marco Fiore, Elzbieta Bylina, Mathias Hoiczyk, Annemieke Cats, Paolo G. Casa
Annals of Surgical Oncology.2013; 20(9): 2937. CrossRef
- Safety, effectiveness and the optimal duration of preoperative imatinib in locally advanced gastric gastrointestinal stromal tumors: A retrospective cohort study
Review
- Pruritus Ani
- Seok-Gyu Song, Soung-Ho Kim
- J Korean Soc Coloproctol. 2011;27(2):54-57. Published online April 30, 2011
- DOI: https://doi.org/10.3393/jksc.2011.27.2.54
- 19,757 View
- 138 Download
- 11 Citations
-
Abstract
PDF
Pruritus ani is an unpleasant cutaneous sensation that induces the desire to scratch the skin around the anal orifice. It may start insidiously and appears in 1% to 5% of the population. It is classified as primary (idiopathic) pruritus ani when no cause can be found. However, as 25% to 75% of cases have co-existing pathology, a detailed history and examination are necessary. The goal of treatment is asymptomatic, intact, dry, clean perianal skin with reversal of morphological changes. The management of pruritus ani is directed towards the underlying cause. If the diagnosis is idiopathic pruritus ani, the patients can still be managed with great success by eliminating of irritants and scratching, by giving general advice regarding hygiene and lifestyle modification and by using active treatment measures.
-
Citations
Citations to this article as recorded by- Practical guide for the diagnosis and treatment of localized and generalized cutaneous pruritus (chronic itch with no underlying pruritic dermatosis)
Takashi Hashimoto, Satoshi Okuno
The Journal of Dermatology.2025; 52(2): 204. CrossRef - Practice Parameters for Evaluation and Management of Pruritus Ani on Behalf of the Italian Society of Colorectal Surgery (SICCR)
Fabio Marino, Jacopo Martellucci, Maria Carmela Giuffrida, Giorgio La Greca, Amanda Belluzzi, Luigi Losacco, Fabio Ambrosini, Simone Orlandi, Claudia Menconi, Paola De Nardi, Corrado Bottini
Journal of Cutaneous Medicine and Surgery.2025;[Epub] CrossRef - Pruritus Ani—Not an Itch that Can Be Ignored
Roy Mahapatra, Brooke Davies, Matthew Fok, Jennie Grainger
Indian Journal of Surgery.2024; 86(2): 281. CrossRef - Experience of using homeopathic ointment in the treatment of patients with anal itching
L. A. Lichman, S. E. Katorkin, P. S. Andreev, O. E. Davydova
Ambulatornaya khirurgiya = Ambulatory Surgery (Russia).2024; 21(1): 100. CrossRef - Adsorption behavior of methylene blue using purified moroccan clay/alginate beads: response surface methodology optimization
El Mustafa Iboustaten, Roberta Bertani, Karim Tanji, Imane El Mrabet, Youssef Fahoul, Paolo Sgarbossa, Mohamed Ezzejjari, Abdelhak Kherbeche
Reaction Kinetics, Mechanisms and Catalysis.2023; 136(3): 1563. CrossRef - Pruritis ani
Josiah Damisa, Ertan Teodorescu, Sanjay Harrison
InnovAiT: Education and inspiration for general practice.2022; 15(6): 336. CrossRef - Be Kind to Your Behind: A Systematic Review of the Habitual Use of Bidets in Benign Perianal Disease
Zarrukh Baig, Nawaf Abu-Omar, Michael Harington, Dilip Gill, David Nathan Ginther, Guy Cohen
Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1. CrossRef - SOOTHER TRIAL: Observational study of an over-the-counter ointment to heal anal itch
Isaac Felemovicius, Robert A. Ganz, Mohammad Saremi, William Christopfel
Frontiers in Medicine.2022;[Epub] CrossRef - Survey of electric bidet toilet use among community dwelling Japanese people and correlates for an itch on the anus
Akira Tsunoda, Tomoko Takahashi, Kaori Arika, Sachiyo Kubo, Takeshi Tokita, Shogo Kameda
Environmental Health and Preventive Medicine.2016; 21(6): 547. CrossRef - Anorectal Complaints in the Emergency Department
Christina Lynn Tupe, Thuy Van Pham
Emergency Medicine Clinics of North America.2016; 34(2): 251. CrossRef - Efficacy of topical tacrolimus for the treatment of persistent pruritus ani in patients with atopic dermatitis
Haydar Ucak, Betul Demir, Demet Cicek, Selma Bakar Dertlioglu, Zeynep Meltem Akkurt, Derya Ucmak, Nurhan Halisdemir
Journal of Dermatological Treatment.2013; 24(6): 454. CrossRef
- Practical guide for the diagnosis and treatment of localized and generalized cutaneous pruritus (chronic itch with no underlying pruritic dermatosis)
Original Articles
- Management of Appendicitis Presenting with Abscess or Mass
- Jeong-Ki Kim, Seungbum Ryoo, Heung-Kwon Oh, Ji Sun Kim, Rumi Shin, Eun Kyung Choe, Seung-Yong Jeong, Kyu Joo Park
- J Korean Soc Coloproctol. 2010;26(6):413-419. Published online December 31, 2010
- DOI: https://doi.org/10.3393/jksc.2010.26.6.413
- 9,279 View
- 76 Download
- 29 Citations
-
Abstract
PDF
Purpose Management strategy in acute appendicitis patients initially presenting with abscess or mass is surrounded with controversy. This study was performed to identify the outcomes of management for this condition.
Methods We retrospectively analyzed prospectively registered 76 patients (male:female = 39:37; mean age, 50.8 years) with appendicitis presenting with abscess or mass over a 9-year period at the Seoul National University Hospital. Patients were divided into three groups (emergency operation group, delayed operation group, and follow-up group), and clinical characteristics and outcomes of treatment were investigated.
Results Twenty-eight patients (36.8%) underwent an emergency operation. Of the remaining 48 patients, 20 (41.7%) were initially treated with conservative management through the use of antibiotics only; the other 28 (58.3%) with and additional ultrasound-guided percutaneous drainage of the abscess. Twenty-six (54.2%) patients underwent planned operations after conservative management, and 22 (45.8%) were followed without surgery (median duration, 37.8 month), of which 3 (13%) underwent an appendectomy due to recurrent appendicitis (mean of 56.7 days after initial attack). There were no statistical differences in types of operation performed (appendectomy or ileocecectomy), postoperative complications, and postoperative hospital stay among the patients who underwent emergency operations, delayed operations and operations for recurrence during follow-up.
Conclusion Although the recurrence rate was relatively low after conservative management for appendicitis patients presenting with abscess or mass, there was no difference in surgical outcome between the emergent, elective, or recurrent groups. Our results indicate that proper management of appendicitis with abscess or mass can be selected according to surgeon's preference.
-
Citations
Citations to this article as recorded by- Primary Non-Surgical Treatment in Pediatric Complicated Appendicitis: Does Abscess Size Matter?
Merle Koerner, Safiullah Najem, Nariman Mokhaberi, Vasileios Vasileiadis, Annette Aigner, Julia Elrod, Konrad Reinshagen, Ingo Koenigs
Journal of Pediatric Surgery Open.2026; : 100262. CrossRef - High Diagnostic Accuracy but Persistent Risk of Complicated Appendicitis: A Retrospective Analysis from Hail Province, Saudi Arabia
Alfatih Mohamed Ahmed Aljanib, Faisal Fawaz Alshammari, Fahad Maiyah Alshammari, Ali Ahmed Alqahtani, Bandar Alsaif, Jerold C. Alcantara, Abdulaziz Bin Ali Alshammari, Talal Alharazi
International Journal of Applied & Basic Medical Research.2025; 15(2): 85. CrossRef - A Case of Appendiceal Pinworms in an Adolescent Patient
Zachary S Kauffman, David L Stuart
Cureus.2025;[Epub] CrossRef - From Bedside to Bot-Side: Artificial Intelligence in Emergency Appendicitis Management
Koray Ersahin, Sebastian Sanduleanu, Sithin Thulasi Seetha, Johannes Bremm, Cavid Abbasli, Chantal Zimmer, Tim Damer, Jonathan Kottlors, Lukas Goertz, Christiane Bruns, David Maintz, Nuran Abdullayev
Life.2025; 15(9): 1387. CrossRef - Comparison of outcomes of nonoperative management with versus without interval appendectomy for periappendiceal abscess in Korea: a retrospective cohort study
Jae Gil Lee, Chang Sung Park, Im Kyung Kim
Journal of Acute Care Surgery.2025; 15(3): 108. CrossRef - Study on the Curative Effect of Different Treatment Methods on 122 Cases of Periappendiceal Abscess
哲魁 刘
Advances in Clinical Medicine.2024; 14(03): 85. CrossRef - Early Surgical Management of Appendicular Mass: Evaluation of Surgical Outcome in Selected Private and Government Hospitals, Bangladesh
Jahangir Sarwar, Abul Shamsuddin, Sirajam Munira
Clinical Medicine Research.2024; 13(3): 33. CrossRef - Failure to Significantly Reduce Radiation Exposure in Children with Suspected Appendicitis in the United States
Charbel Chidiac, Oussama Issa, Alejandro V. Garcia, Daniel S. Rhee, Mark B. Slidell
Journal of Pediatric Surgery.2024; 59(12): 161701. CrossRef - Intra-abdominal abscesses: Microbiological epidemiology and empirical antibiotherapy
F. Méchaï, A. Kolakowska, E. Carbonnelle, O. Bouchaud, C. Tresallet, F. Jaureguy
Infectious Diseases Now.2023; 53(1): 104604. CrossRef - Upfront appendectomy vs interval appendectomy in acute appendicitis with mass formation in pediatric age group: Little difference in major outcome
Hussam Widatella, Ahmed Abdulmanan, Ibraheem Abdelraheem, Fadi Atwan, Sri Paran
Journal of Pediatrics & Neonatal Care.2023; 13(2): 137. CrossRef - Diagnosis and treatment of appendicitis: systematic review and meta-analysis
Ryan Lamm, Sunjay S. Kumar, Amelia T. Collings, Ivy N. Haskins, Ahmed Abou-Setta, Nisha Narula, Pramod Nepal, Nader M. Hanna, Dimitrios I. Athanasiadis, Stefan Scholz, Joel F. Bradley, Arianne T. Train, Philip H. Pucher, Francisco Quinteros, Bethany Slate
Surgical Endoscopy.2023; 37(12): 8933. CrossRef - Thigh and iliopsoas abscess as a rare presentation of perforated mucinous appendix carcinoma. A case report
Pedro Osácar, Darío Ramallo, Luisina Elizalde
International Journal of Surgery Case Reports.2022; 96: 107293. CrossRef - Early versus delayed (interval) appendicectomy for the management of appendicular abscess and phlegmon: a systematic review and meta-analysis
Akinfemi A. Akingboye, Fahad Mahmood, Shafquat Zaman, Jenny Wright, Fatima Mannan, Ali Yasen Y. Mohamedahmed
Langenbeck's Archives of Surgery.2021; 406(5): 1341. CrossRef - Potential Benefit of Nonsurgical Management to Periappendicular Abscess
Chris Li, Dean Owyang
JAMA Surgery.2019; 154(9): 882. CrossRef - Potential Benefit of Nonsurgical Management to Periappendicular Abscess—Reply
Paulina Salminen, Jari Mällinen, Tero Rautio
JAMA Surgery.2019; 154(9): 883. CrossRef - Clinical outcomes of single‐site laparoscopic interval appendectomy for severe complicated appendicitis: Comparison to conventional emergency appendectomy
Masaaki Miyo, Shoichiro Urabe, Satoshi Hyuga, Tomo Nakagawa, Toshiya Michiura, Nobuyasu Hayashi, Kazuo Yamabe
Annals of Gastroenterological Surgery.2019; 3(5): 561. CrossRef - Comparison of treatment methods of appendiceal mass and abscess: A prospective Cohort Study
Zaza Demetrashvili, George Kenchadze, Irakli Pipia, Kakhi Khutsishvili, David Loladze, Eka Ekaladze, Giorgi Merabishvili, George Kamkamidze
Annals of Medicine and Surgery.2019; 48: 48. CrossRef - MANAGEMENT OF APPENDICULAR LUMP AT TERTIARY CARE HOSPITAL
Ishfaq Ahmad Gilkar, Umer Mushtaq, Javid Ahmad Peer, Bilal Ahmed Mir, Yaqoob Hassan, Waseem Ahmad Dar
Journal of Evidence Based Medicine and Healthcare.2019; 6(3): 135. CrossRef - CLINICAL STUDY AND MANAGEMENT OF APPENDICULAR LUMP
Farooq Ahmed, Ravindra G Devani, Mohammed Moinuddin, Mohd. Ashfaq Ahmed
Journal of Evidence Based Medicine and Healthcare.2018; 5(11): 997. CrossRef - The evolving management of the appendix mass in the era of laparoscopy and interventional radiology
James Forsyth, Konstantinos Lasithiotakis, Mark Peter
The Surgeon.2017; 15(2): 109. CrossRef - Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference
Massimo Sartelli, Fausto Catena, Fikri M. Abu-Zidan, Luca Ansaloni, Walter L. Biffl, Marja A. Boermeester, Marco Ceresoli, Osvaldo Chiara, Federico Coccolini, Jan J. De Waele, Salomone Di Saverio, Christian Eckmann, Gustavo P. Fraga, Maddalena Giannella,
World Journal of Emergency Surgery.2017;[Epub] CrossRef - Minimally Invasive Treatment for Appendiceal Mass Formed After Acute Perforated Appendicitis
Enver Zerem, Suad Kunosić, Almin Handanagić, Dženan Jahić, Dina Zerem, Omar Zerem
Surgical Laparoscopy, Endoscopy & Percutaneous Techniques.2017; 27(3): 132. CrossRef - Therapeutic Consideration of Periappendiceal Abscess: an Evaluation of Non-surgical Treatment Followed by Minimally Invasive Interval Appendectomy
Yeong-Soo Jo, Song-Soo Yang, Yeong-Chul Im, Dong-Jin Park, Gyu-Yeol Kim
The Journal of Minimally Invasive Surgery.2017; 20(4): 129. CrossRef - The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections
Massimo Sartelli, Alain Chichom-Mefire, Francesco M. Labricciosa, Timothy Hardcastle, Fikri M. Abu-Zidan, Abdulrashid K. Adesunkanmi, Luca Ansaloni, Miklosh Bala, Zsolt J. Balogh, Marcelo A. Beltrán, Offir Ben-Ishay, Walter L. Biffl, Arianna Birindelli, M
World Journal of Emergency Surgery.2017;[Epub] CrossRef - Diagnosis and management of acute appendicitis. EAES consensus development conference 2015
Ramon R. Gorter, Hasan H. Eker, Marguerite A. W. Gorter-Stam, Gabor S. A. Abis, Amish Acharya, Marjolein Ankersmit, Stavros A. Antoniou, Simone Arolfo, Benjamin Babic, Luigi Boni, Marlieke Bruntink, Dieuwertje A. van Dam, Barbara Defoort, Charlotte L. Dei
Surgical Endoscopy.2016; 30(11): 4668. CrossRef - Challenges in uncomplicated acute appendicitis
Fernando Resende, Ana Beatriz Almeida, José Costa Maia, Renato Bessa Melo
Journal of Acute Disease.2016; 5(2): 109. CrossRef - Management of Appendiceal Mass and Abscess. An 11-Year Experience
Zaza Demetrashvili, Giorgi Kenchadze, Irakli Pipia, Eka Ekaladze, George Kamkamidze
International Surgery.2015; 100(6): 1021. CrossRef - The role of current methods of X-ray diagnosis in caseof intraabdominal suppurative conplications caused bu colonic diseases
A. M. Karsanov, A. A. Kul'chiev, T. R. Karaev, I. P. Kokaev, V. V. Vahotskij
Khirurgiya. Zhurnal im. N.I. Pirogova.2015; (5): 75. CrossRef - 2013 WSES guidelines for management of intra-abdominal infections
Massimo Sartelli, Pierluigi Viale, Fausto Catena, Luca Ansaloni, Ernest Moore, Mark Malangoni, Frederick A Moore, George Velmahos, Raul Coimbra, Rao Ivatury, Andrew Peitzman, Kaoru Koike, Ari Leppaniemi, Walter Biffl, Clay Cothren Burlew, Zsolt J Balogh,
World Journal of Emergency Surgery.2013;[Epub] CrossRef
- Primary Non-Surgical Treatment in Pediatric Complicated Appendicitis: Does Abscess Size Matter?
- International society of university colon and rectal surgeons survey of surgeons’ preference on rectal cancer treatment
- Published online November 30, 1999
- 682 View
- 0 Download
-
Abstract
- tive watchful waiting following chemoradiotherapy, with or without, additional chemotherapy. Our goal was to assess the personal opinion of active practicing surgeons on rectal cancer treatment if he/she was the patient.
Methods
A panel of the International Society of University Colon and Rectal Surgeons (ISUCRS) selected 10 questions that were included in a questionnaire that included other items including demographics. The questionnaire was distributed electronically to ISUCRS fellows and other surgeons included in our database and remained open from April 16 to 28, 2020.
Results
One hundred sixty-three specialists completed the survey. The majority of surgeons (n=65, 39.9%) chose the minimally invasive (laparoscopic) surgery for their personal treatment of rectal cancer. For low-lying rectal cancer T1 and T2, the treatment choice was standard chemoradiation+local excision (n=60, 36.8%) followed by local excision±chemoradiotherapy if needed (n=55, 33.7%). In regards to locally advanced low rectal cancer T3 or greater, the preference of the responders was for laparoscopic surgery (n=65, 39.9%). We found a statistically significant relationship between surgeons’ age and their preference for minimally invasive techniques demonstrating an age-based bias on senior surgeons’ inclination toward open approach.
Conclusion
Our survey reveals an age-based preference by surgeons for minimally invasive surgical techniques as well as organ-preserving techniques for personal treatment of treating rectal cancer. Only 1/4 of specialists do adhere to the international guidelines for treating early rectal cancer.
- Management of Right Colon Diverticulitis.
- Jang, Jong Ik , Lim, Yang Soo , Choi, Jong Woo , Lee, Yoon Sik
- J Korean Soc Coloproctol. 2010;26(1):22-28.
- DOI: https://doi.org/10.3393/jksc.2010.26.1.22
- 14,469 View
- 20 Download
- 4 Citations
-
Abstract
PDF
- PURPOSE
There are still many controversial aspects in the management of right colon diverticulitis. The aim of this study is to find an appropriate treatment for right colon diverticulitis.
METHODS
We retrospectively reviewed the medical records of 88 patients who were admitted with right colon diverticulitis to Wallace Memorial Baptist Hospital from January 2001 to December 2007.
RESULTS
The patients enrolled in this study included 52 men and 36 women. The mean age was 39.6 yr, ranging from 13 to 84 yr. Fifty-four of 88 patients underwent conservative treatment for right colon diverticulitis, and 34 of 88 patients underwent operative treatment. There were 5 cases of recurrence in the conservative treatment group, but there were no cases of recurrence in the operative treatment group. We experienced 43 cases with right colon diverticulitis at the operational fields, including 9 cases that underwent conservative treatment after an appendectomy: eleven cases that underwent conservative treatment after an appendectomy or an appendectomy with diverticulectomy, 19 cases that underwent an ileocecectomy, and 13 cases that underwent a right hemicolectomy. There were no statistically significant difference in complications among 3 groups (P=0.148). However, there were statistical differences among the 3 groups in the length of hospital stay (P=0.016), and the use of intravenous antibiotics (P<0.001), and the use of oral antibiotics (P=0.019).
CONCLUSION
When the preoperative diagnosis is exact, uncomplicated right colon diverticulitis can be managed by conservative treatment. On the other hand, an ileocecectomy or a right hemicolectomy is the proper treatment for complicated right colon diverticulitis. However, if uncomplicated right colon diverticulitis is diagnosed intraoperatively, conservative treatment or a diverticulectomy should be considered. -
Citations
Citations to this article as recorded by- Primary epiploic appendagitis: Reconciling CT and clinical challenges
Jamel Saad, Hussein Ali Mustafa, Asem Mohamed Elsani, Fawaz Alharbi, Saad Alghamdi
Indian Journal of Gastroenterology.2014; 33(5): 420. CrossRef - Management of Right Colonic Uncomplicated Diverticulitis: Outpatient Versus Inpatient Management
Hyoung‐Chul Park, Byoung Seup Kim, Bong Hwa Lee
World Journal of Surgery.2011;[Epub] CrossRef - Clinical Characteristics of Primary Epiploic Appendagitis
Young Un Choi, Pyong Wha Choi, Yong Hwan Park, Jae Il Kim, Tae Gil Heo, Je Hoon Park, Myung Soo Lee, Chul Nam Kim, Surk Hyo Chang, Jeong Wook Seo
Journal of the Korean Society of Coloproctology.2011; 27(3): 114. CrossRef - A Case of Ascending Colon Diverticulitis with Perforation in a Child
Joon Woo Baek, Jae Young Shin, Jee Hyun Lee, So Young Jung, Ah Young Jung, Jeong Won Kim, Kon Hee Lee
Korean Journal of Pediatric Gastroenterology and Nutrition.2010; 13(2): 193. CrossRef
- Primary epiploic appendagitis: Reconciling CT and clinical challenges
- The Necessity of a Routine Interval Appendectomy Necessary in Adults?: Initial Experience.
- Park, Jong Deok , Lee, Chang Ho , Kim, Jong Hun , Kim, Yong Kon , Lee, Min Ro
- J Korean Soc Coloproctol. 2010;26(1):12-16.
- DOI: https://doi.org/10.3393/jksc.2010.26.1.12
- 14,347 View
- 19 Download
-
Abstract
PDF
- PURPOSE
The traditional management of a periappendiceal abscess or a perforated appendicitis has been initial conservative treatment, followed by an interval appendectomy (IA). However, the necessity of the interval appendectomy has been questioned by an increasing number of studies recently. The purpose of this study was to clarify the role of conservative treatment, instead of IA, in managing a perforated appendicitis or a periappendiceal abscess after successful initial conservative treatment.
METHODS
We prospectively studied 26 out of 80 patients who had been admitted for a perforated appendicitis or a periappendiceal abscess to Chonbuk National University Hospital from March 2005 to December 2007. These 26 patients were initially treated by using conservative treatment instead of surgery. We analyzed these 26 patients' progression and prognosis after treatment. The IAs were conducted at intervals of 6 to 12 wk after colonoscopy when the patient wanted an operation.
RESULTS
Twenty-three out of 26 (88.5%, 23/26) patients were improved after initial conservative treatment. Only 3 patients who were not improved were managed surgically. Four out of 23 patients who were relieved by conservative treatment underwent an IA voluntarily at intervals of 6 to 12 wk. Of the remaining 19 patients without IA, 1 patient (5%, 1/19) suffered a recurrence after 6 mo, and an appendectomy was performed. Eighteen (78%, 18/23) patients without an IA have shown no recurrence for 15 mo, and they are still being followed up.
CONCLUSION
We conclude that a routine IA after successful initial conservative treatment for a perforated appendicitis or a periappendiceal abscess seems unnecessary. Those patients should undergo colonoscopy to detect any underlying diseases and to rule out coexistent colorectal cancer.
- Clinicopathologic Analysis of Gastrointestinal Stromal Tumors of the Colon and Rectum.
- Choi, Sung Hoon , Kim, Seo Jeon , Choi, Yun Jung , Min, Byung So , Kim, Jin Su , Baik, Seung Hyuk , Kim, Nam Kyu , Kang, Jung Gu
- J Korean Soc Coloproctol. 2009;25(5):323-333.
- DOI: https://doi.org/10.3393/jksc.2009.25.5.323
- 2,888 View
- 9 Download
- 4 Citations
-
Abstract
PDF
- PURPOSE
This study's aim is to investigate the clinicopathologic characteristics of colorectal gastrointestinal stromal tumors (GISTs) and to evaluate the result of those tumors.
METHODS
We retrospectively reviewed 22 patients who had been diagnosed with primary colorectal GISTs and who had undergone a surgical resection between October 1996 and July 2008.
RESULTS
Colorectal GISTs accounted for 0.28% of all colorectal malignancies and 7.7% of all GISTs. Rectal GISTs (19, 86.4%) were more common than colonic GISTs (3, 13.6%). According to the National Institute of Health's (NIH) grading system, there were 1 (4.5%) very low, 5 (22.7%) low, 4 (18.2%) intermediate, and 12 (54.6%) high-risk tumors. The disease recurred in 7 patients (1 with intermediate risk and 6 with high risk). Recurrence sites were the liver (42.9%), the peritoneum (71.5%), and the lymph nodes (14.3%). Adjuvant imatinib therapy and/or radiation therapy were done for patients with microscopically positive margins of resection and high risk, of which one experienced a recurrence at 95 months after surgery. The five-year recurrence rates were 0% in the very-low-grade and low-grade groups, 33.3% in the intermediate-grade group, and 37.5% in the high-grade group. The five-year overall survival rates were 100% in the very-low-grade and low-grade groups, 66.7% in the intermediate-grade group, and 62.5% in the high-grade group.
CONCLUSION
Poor prognosis of colorectal GISTs was closely related to the tumor's histologic grade and size. Integrating surgery, molecular therapy, and radiation therapy might improve outcomes, but further study with more cases is needed. -
Citations
Citations to this article as recorded by- Transanal endoscopic microsurgery with alternative neoadjuvant imatinib for localized rectal gastrointestinal stromal tumor: a single center experience with long-term surveillance
Xueshan Bai, Weixun Zhou, Yunhao Li, Guole Lin
Surgical Endoscopy.2021; 35(7): 3607. CrossRef - Primary localized rectal/pararectal gastrointestinal stromal tumors: results of surgical and multimodal therapy from the French Sarcoma group
Thanh-Khoa Huynh, Pierre Meeus, Philippe Cassier, Olivier Bouché, Sophie Lardière-Deguelte, Antoine Adenis, Thierry André, Julien Mancini, Olivier Collard, Michael Montemurro, Emmanuelle Bompas, Maria Rios, Nicolas Isambert, Didier Cupissol, Jean-Yves Bla
BMC Cancer.2014;[Epub] CrossRef - Efficacy of Imatinib Mesylate Neoadjuvant Treatment for a Locally Advanced Rectal Gastrointestinal Stromal Tumor
Kyu Jong Yoon, Nam Kyu Kim, Kang Young Lee, Byung Soh Min, Hyuk Hur, Jeonghyun Kang, Sarah Lee
Journal of the Korean Society of Coloproctology.2011; 27(3): 147. CrossRef - Multiple Colonic Metastases from Hepatocellular Carcinoma
Gwi Hong Jeong, Byong Duk Ye, Seung Jae Myung
The Korean Journal of Gastroenterology.2011; 58(5): 288. CrossRef
- Transanal endoscopic microsurgery with alternative neoadjuvant imatinib for localized rectal gastrointestinal stromal tumor: a single center experience with long-term surveillance
- Endoscopic Submucosal Dissection for Colorectal Neoplasia: Early Outcomes After 260 Cases.
- Lee, Eun Jung , Lee, Jae Bum , Lee, Suk Hee , Kim, Do Sun , Lee, Doo Han , Youk, Eui Gon
- J Korean Soc Coloproctol. 2009;25(3):157-164.
- DOI: https://doi.org/10.3393/jksc.2009.25.3.157
- 2,585 View
- 30 Download
- 1 Citations
-
Abstract
PDF
- PURPOSE
Endoscopic submucosal dissection (ESD), a recently introduced endoscopic technique, makes it possible to perform an en-bloc resection of a lesion regardless of its size. The aim of this study was to report early experiences with colorectal ESD performed in our hospital.
METHODS
Between October 2006 and December 2008, we performed an ESD for 260 consecutive cases of colorectal neoplasia in 255 patients. We evaluated the clinical outcomes, except for two failure cases of bowel perforation.
RESULTS
The mean resected tumor size was 24.2+/-9.8 (5-60) mm. Our overall endoscopic en-bloc resection rate was 93.0% (240/258). and the pathologically margin free rate was 91.5% (236/258). Perforation occurred in 7.7% (20/260) of the cases. In 17 patients, perforation was managed by endoscopic clipping without salvage surgery; the other three patients underwent a laparoscopic operation. Pathological examination showed an adenocarcinoma in 35.4% of the cases (92/260). We recommended additional radical surgery in 13 cases (submucosal invasion less than 1 mm with unfavorable pathology: 1 case; unknown depth of submucosal invasion: 1 case; submucosal invasion > or =1 mm: 9 cases; invasion to proper muscle: 2 cases). We were able to check the recurrence rate through colonoscopy for 125 patients. During the mean follow-up period of 8.0+/-4.3 (3-21) mo, there were no recurrences.
CONCLUSION
ESD was technically difficult, had a substantial risk of perforation, and needed a long procedure time. However, ESD enabled en-bloc resection of large colorectal tumors. As experience with the technique increases, ESD might gradually replace piecemeal endoscopic mucosal resection (EMR) and radical colon resection in the treatment of colorectal tumors. -
Citations
Citations to this article as recorded by- Follow-up Results of Endoscopic Mucosal Resection for Early Colorectal Cancer
Hee Jung Lee, Hyun Yong Jeong, Nam Hwan Park, Sun Chang Hong, Gwan Woo Nam, Hee Seok Moon, Eaum Seok Lee, Seok Hyun Kim, Jae Kyu Sung, Byung Seok Lee
The Korean Journal of Gastroenterology.2011; 57(4): 230. CrossRef
- Follow-up Results of Endoscopic Mucosal Resection for Early Colorectal Cancer
- Long-term Result of Surgical Treatment for Crohn's Enteritis.
- Choi, Sang Ji , Choe, Eun Kyung , Park, Sung Chan , Park, Kyu Joo
- J Korean Soc Coloproctol. 2008;24(6):409-416.
- DOI: https://doi.org/10.3393/jksc.2008.24.6.409
- 1,897 View
- 7 Download
-
Abstract
PDF
- PURPOSE
We sought to determine the long-term outcome of surgical management for gastrointestinal Crohns's disease (CD) and to find out whether there is any improvement over the time period.
METHODS
We analyzed the records of the 102 patients who underwent surgery for gastrointestinal CD excluding perianal CDbetween 1978 and 2007. A cumulative surgical recurrence rate was analyzed by Kaplan-Meier plots and log-rank tests.
RESULTS
The main sites of CD were ileocecal area in 54.5%, followed by small bowel (29.7%) and large bowel (7.9%). Common indications for operation were obstruction (25.7%), diagnostic purpose (20.8%), and failure of medical treatment (12.9%). The operation performed were ileocolectomy including right hemicolectomy in 53 cases (45.3%), small bowel resection in 38 cases (31.7%), and strictureplasty 12 cases (10.0%, including 11 cases combined with bowel resection). The average follow-up period after operation was 6.4years (range: 0.5~29 yr, median: 5.3 yr). Among all patients, 22 (21.6%) underwent operations for recurrence. The re-operation rate was higher in the younger patients group (age at diagnosis less than 25 years) (34.1% vs. 12.1%, P<0.05), and in case of the patients whose length of initial intestinal resection was less than 40 cm (27.9% vs. 7.7%, P<0.05). The overall cumulative re-operation rates at 5years, 10years and 15years were 15%, 25%, and 60%, respectively.
CONCLUSIONS
Despite recent advances in medical therapy, the cumulative re-operation rate of patients operated for gastrointestinal CD remains similar to our previous report in 1997.
- Patterns of Recurrence and Prognosis in Patients with Intestinal Behcet's Disease Who Underwent a Bowel Resection.
- Hur, Hyuk , Min, Byung Soh , Kim, Jin Soo , Lee, Kang Young , Park, Yoon Ah , Baik, Seung Hyuk , Sohn, Seung Kook , Cho, Chang Hwan , Kim, Jae Hak , Kim, Won Ho , Kim, Nam Kyu
- J Korean Soc Coloproctol. 2008;24(3):166-174.
- DOI: https://doi.org/10.3393/jksc.2008.24.3.166
- 2,507 View
- 15 Download
- 4 Citations
-
Abstract
PDF
- PURPOSE
We aim to analyze the clinical course and the recurrence patterns after surgical treatment in patients with intestinal Behcet's disease and to determine the prognostic factors. METHODS: Thirty-eight patients with intestinal Behcet's disease who had undergone operations between 1979 and 2007 were analyzed. Clinical characteristics between the recurrent group (n=24) and the non-recurrent group (n=14) were compared. The cumulative recurrence rates were calculated by using the Kaplan-Meier method, and the results were compared by using the log-rank test. RESULTS: The median follow-up was 120 months. The median age of the 38 patients was 36.5 years, and the patients included 26 males and 12 females. Recurrences after surgical treatment were observed in 24 patients, and reoperations were performed in 21 patients. The mean age at operation was 35.7 years in the recurrent group and was less than 43.4 years in the non-recurrent group (P=0.030). Clinical subtypes of Behcet's disease (complete or incomplete vs. suspicious) and the cause of operation (presence vs. absence of a perforation or fistula) were different between the recurrent and the non-recurrent groups (P=0.048, P=0.014, respectively). The 5-year cumulative recurrence rate and reoperation rate for all patients with intestinal Behcet's disease who underwent operations were 52.7% and 36.0%, respectively the clinical subtypes and the cause of the operation were significant factors affecting the cumulative recurrence and the reoperation rates.
CONCLUSIONS
Intestinal Behcet's disease demonstrates high recurrence and reoperation rates after surgical treatment. More careful follow up is needed to these surgical patients with high risk of recurrence and reoperation. -
Citations
Citations to this article as recorded by- Short- and long-term outcomes of surgical treatment in patients with intestinal Behcet’s disease
Min Young Park, Yong Sik Yoon, Jae Ha Park, Jong Lyul Lee, Chang Sik Yu
World Journal of Gastrointestinal Surgery.2024; 16(2): 429. CrossRef - Evidence-based diagnosis and clinical practice guidelines for intestinal Behçet’s disease 2020 edited by Intractable Diseases, the Health and Labour Sciences Research Grants
Kenji Watanabe, Satoshi Tanida, Nagamu Inoue, Reiko Kunisaki, Kiyonori Kobayashi, Masakazu Nagahori, Katsuhiro Arai, Motoi Uchino, Kazutaka Koganei, Taku Kobayashi, Mitsuhiro Takeno, Fumiaki Ueno, Takayuki Matsumoto, Nobuhisa Mizuki, Yasuo Suzuki, Tadakaz
Journal of Gastroenterology.2020; 55(7): 679. CrossRef - Prognostic factors and long-term clinical outcomes for surgical patients with intestinal Behcetʼs disease
Yoon Suk Jung, Jin Young Yoon, Jin Ha Lee, Soung Min Jeon, Sung Pil Hong, Tae Il Kim, Won Ho Kim, Jae Hee Cheon
Inflammatory Bowel Diseases.2011; 17(7): 1594. CrossRef - Response Rates to Medical Treatments and Long-term Clinical Outcomes of Nonsurgical Patients With Intestinal Behçet Disease
Moon Jae Chung, Jae Hee Cheon, Seung Up Kim, Jae Jun Park, Tae Il Kim, Nam Kyu Kim, Won Ho Kim
Journal of Clinical Gastroenterology.2010; 44(6): e116. CrossRef
- Short- and long-term outcomes of surgical treatment in patients with intestinal Behcet’s disease
Review
- The Roles of Anorectal Physiologic Tests and Treatment of Chronic Constipation.
- Hwang, Yong Hee
- J Korean Soc Coloproctol. 2008;24(2):148-159.
- DOI: https://doi.org/10.3393/jksc.2008.24.2.148
- 2,333 View
- 15 Download
-
Abstract
PDF
- Patients with chronic constipation should be evaluated with physiological tests (defecography and cinedefecography, anal manometry, anal electromyography, and colon transit time) after structural disorders and extracolonic causes have been excluded. In the case of colonic inertia, at first, conservative treatment is necessary. If surgery is indicated, a subtotal colectomy with ileorectal anastomosis is the treatment of choice. Biofeedback is the best option for animus. For patients failing biofeedback, botulinum toxin injection of the puborectalis or sacral nerve stimulation may be indicated. Biofeedback treatment is also considered to be an option for moderate-degree rectoceles, rectal intussusception, and perineal descending syndrome. For the treatment of a severe rectocele, a surgical approach, including transrectal, transvaginal, and transperineal repair or stapled transanal rectal resection (STARR) should be considered. However, the long-term effects of a new technique including botulinum toxin injection, sacral nerve stimulation, and STARR remain to be established.
Original Articles
- Adult Intussusception: Diagnosis and Treatment.
- Yang, Jae Do , Lee, Min Ro , Kim, Jong Hun
- J Korean Soc Coloproctol. 2007;23(6):416-419.
- DOI: https://doi.org/10.3393/jksc.2007.23.6.416
- 2,859 View
- 22 Download
- 2 Citations
-
Abstract
PDF
- PURPOSE
Adult intussusception occurs infrequently and differs greatly from childhood intussusception in etiology. Proper diagnostic of and surgical therapeutic methods for adult intussusception remain controversial. The aim of this study was to determine useful diagnostic modalities and proper surgical interventions in adult intussusception.
METHODS
A retrospective analysis performed at Chonbuk National University Hospital identified 38 patients, aged 15 and older, with a diagnosis of intussusception from January 1991 to January 2007.
RESULTS
There were 19 males and 19 females. The median age of the group was 44 years with a range of 20 to 80 years. The mean follow-up period was 82 months. Abdominal pain was the most common presenting complaint (89%). There were 30 small bowel intussusceptions and 8 colonic intussusceptions. A pathologic cause was identified in 79% of the patients, with 5 of 30 (17%) small bowel and 4 of 8 (50%) large bowel lesions being malignant. A preoperative diagnosis was made accurately in 25 of 38 (66%) patients. The diagnostic rates of pre-operative radiological methods were 77%, 60%, 79%, and 100% for barium enema, ultrasonography, abdominal computerized tomography, and both ultrasonography and abdominal computerized tomography, respectively. Operative treatment consisted of manual reduction only in 6 small bowel (20%) and 1 large bowel intussusception (12%), bowel resection after manual reduction in 8 small bowel (27%) and 2 large bowel intussusceptions (24%), and resection alone in 16 small bowel (53%) and 5 large bowel intussusceptions (64%).
CONCLUSIONS
Both ultrasonography and abdominal computerized tomography are the most useful diagnostic modalities. Colonic intussusception should be treated with en-bloc resection without reduction due to the high incidence of malignancy. However, manual reduction only, bowel resection after reduction, and bowel resection alone can be chosen selectively in cases of small bowel intussusception. -
Citations
Citations to this article as recorded by- Adult intussusceptions: preoperative predictive factors for malignant lead point
Kil Hwan Kim, Hwan Namgung, Dong Guk Park
Annals of Surgical Treatment and Research.2014; 86(5): 244. CrossRef - A Case of Small Bowel Intussusception Caused by Jejunal Hamartoma Confused as Hepatitis A in an Adult
Joon Hur, Gu-Min Cho, Young Ook Eum, Ji Young Park, Mi Sung Kim, Byung Seong Ko, Hyang Mi Shin, Seung-Myoung Son
Yeungnam University Journal of Medicine.2012; 29(2): 110. CrossRef
- Adult intussusceptions: preoperative predictive factors for malignant lead point
- Surgical Management of Colonoscopic Perforations.
- Park, Hyoung Chul , Kim, Duck Woo , Kim, Sang Gyun , Park, Kyu Joo , Park, Jae Gahb
- J Korean Soc Coloproctol. 2007;23(5):287-291.
- DOI: https://doi.org/10.3393/jksc.2007.23.5.287
- 2,578 View
- 19 Download
- 4 Citations
-
Abstract
PDF
- PURPOSE
The purpose of this study is to evaluate the clinical features that necessitate a temporary stoma for the treatment of colonoscopic perforations.
RESULTS
Between January 2000 and July 2006, 30 patients were treated for colonoscopic perforation. Based on the perforation sites, we classified these patients into the following groups: proximal colon, sigmoid colon, and rectum; we then reviewed clinical data, including the time to operation and management.
RESULTS
Seventeen patients had a perforation during the diagnostic colonoscopy. Of these patients, 14 patients had sigmoid colon perforation. Six underwent an operation within 10 hours after perforation. Of these six, four were managed by primary repair or resection with anastomosis, one sigmoid colon cancer patient by anterior resection, and one rectal cancer patient by low anterior resection with diverting ileostomy. Eight patients underwent more than 12 hours after perforation. Of these eight, three were managed by resection with anastomosis and diverting ileostomy and five by resection with end colostomy. Thirteen patients had a perforation during the therapeutic colonoscopy. Of these patients, 10 patients had a proximal colon perforation. Of these 10, 3 without fever or peritonitis symptom were managed by conservative management, 6 by primary repair or resection with anastomosis, and 1 transverse colon cancer patient by right hemicolectomy. Three patients had sigmoid colon perforation. Of these three, one was managed by primary repair, one by resection with anastomosis, and one sigmoid colon cancer patient by anterior resection.
CONCLUSIONS
The mechanism of perforation, the site of the perforation, and the time to operation are associated with intraperitoneal contamination and have an influence on surgical treatment. -
Citations
Citations to this article as recorded by- A comparative analysis of traditional meat processing methods
Kasun Dissanayake, Mohamed Rifky, Khabibulla Nurmukhamedov, Jasur Makhmayorov, Bakhodir Abdullayev, Jasur Farmanov, Murodjon Samadiy, T. Itao, V. Perskaya, W. Yanmin, D. Morkovkin
E3S Web of Conferences.2024; 494: 04023. CrossRef - Comparison of the surgical outcomes of laparoscopic versus open surgery for colon perforation during colonoscopy
Jeongsoo Kim, Gil Jae Lee, Jeong-Heum Baek, Won-Suk Lee
Annals of Surgical Treatment and Research.2014; 87(3): 139. CrossRef - Colonoscopic Perforation; A 10-year Experience in Single General Hospital
Ji Eun Oh, Sang Goon Shim
The Korean Journal of Gastroenterology.2009; 54(6): 371. CrossRef - Treatment of Colon Perforation Associated with Colonoscopy
Hae Ran Park, Seong Kyu Baek, Ok Suk Bae, Sung Dae Park
Journal of the Korean Society of Coloproctology.2008; 24(5): 322. CrossRef
- A comparative analysis of traditional meat processing methods
- Diverticulitis of the Right Colon: Tips for Preoperative Diagnosis and Treatment Strategy.
- Lee, In Kyu , Kim, Su Hong , Lee, Yoon Suk , Kim, Hyung Jin , Lee, Sang Kuon , Kang, Won Kyung , Ahn, Chang Hyeok , Oh, Seong Taek , Jeon, Hae Myung , Kim, Jun Gi , Kim, Eung Kook , Chang, Suk Kyun
- J Korean Soc Coloproctol. 2007;23(4):223-231.
- DOI: https://doi.org/10.3393/jksc.2007.23.4.223
- 3,245 View
- 32 Download
- 17 Citations
-
Abstract
PDF
- PURPOSE
The planned therapy of right colonic diverticulitis is very difficult because preoperative diagnosis is uncommon and the method of treatment is usually decided at the time of laparotomy. We retrospectively analyzed the clinical characteristics of right colonic diverticulitis, the clinical distinctions between preoperatively and postoperatively diagnosed patients, the recurrence rate, and the hospital stay by treatment modality.
METHODS
Among 104 patients who were treated for right colonic diverticulitis from January 1997 to May 2005, we enrolled 90 patients who had been diagnosed by the operation or a barium enema study (BE), and who had not been lost to follow-up. Patients were divided into three groups based on treatment modality: Group 1 (n=28), conservative management with intravenous antibiotics; Group 2 (n=46), aggressive resection; Group 3 (n=16), appendectomy with intravenous antibiotics.
RESULTS
Ultrasound and computed tomography (CT) detected 12 (22.6%) and 21 (87.5%) cases of right colonic diverticulitis, respectively. BE was applied to 45 patients, 28 (62.2%) of them with multiple diverticula. Right colonic diverticulitis was the preoperative diagnosis in 39 patients (43.3%). The length of hospital stay was significantly different between the groups (P<0.001): 4.9+/-3.1 days in Group 1, 7.5+/-3.7 days in Group 2, and 3.8+/-0.9 days in Group 3. Two patients (7.1%) in Group 1, 2 patients (4.3%) in Group 2, and 5 patients (31.3%) in Group 3 had recurrent diverticulitis during the follow-up period (P=0.007). The Kaplan-Meier estimated recurrence rates for Groups 1, 2, and 3 were statistically significantly different (P=0.0086).
CONCLUSIONS
To differentiate right colonic diverticulitis from appendicitis, focusing on the peculiar feature in contrast to appendicitis and appropriate utilization of CT are important. If diagnosed preoperatively, uncomplicated right colonic diverticulitis can be managed by conservative management with intravenous antibiotics. If diagnosed intraoperatively, aggressive resection is advocated as the most effective method for decreasing the recurrence rate. -
Citations
Citations to this article as recorded by- Right‐sided acute diverticulitis in a North African country: Presentation and management in one surgical center
Laila Jedidi, Aymen Mabrouk, Hela Ghali, Anis Ben Dhaou, Senda Ben Lahouel, Sami Daldoul, Houyem Said Latiri, Mounir Ben Moussa
World Journal of Surgery.2024; 48(6): 1509. CrossRef - Right-sided acute diverticulitis in the West: experience at a university hospital in Argentina
René M. Palacios Huatuco, Diana A. Pantoja Pachajoa, Julian E. Liaño, Héctor A. Picón Molina, Rafael Palencia, Alejandro M. Doniquian, Matías Parodi
Annals of Coloproctology.2023; 39(2): 123. CrossRef - Caecal diverticulitis can be misdiagnosed as acute appendicitis: a systematic review of the literature
Isabelle Uhe, Jeremy Meyer, Manuela Viviano, Surrennaidoo Naiken, Christian Toso, Frédéric Ris, Nicolas C. Buchs
Colorectal Disease.2021; 23(10): 2515. CrossRef - Laparoscopic diverticulectomy versus non-operative treatment for uncomplicated right colonic diverticulitis
Le Huy Luu, Nguyen Lam Vuong, Vo Thi Hong Yen, Do Thi Thu Phuong, Bui Khac Vu, Nguyen Viet Thanh, Nguyen Thien Khanh, Nguyen Van Hai
Surgical Endoscopy.2020; 34(5): 2019. CrossRef - Clinical differentiation of acute appendicitis and right colonic diverticulitis: A case-control study
Yosuke Sasaki, Fumiya Komatsu, Naoyasu Kashima, Takahiro Sato, Ikutaka Takemoto, Sho Kijima, Tadashi Maeda, Takamasa Ishii, Taito Miyazaki, Yoshiko Honda, Nagato Shimada, Yoshihisa Urita
World Journal of Clinical Cases.2019; 7(12): 1393. CrossRef - Right-sided acute diverticulitis: A single Western center experience
Francesco Monari, Maurizio Cervellera, Basilio Pirrera, Umberto D'Errico, Samuele Vaccari, Laura Alberici, Valeria Tonini
International Journal of Surgery.2017; 44: 128. CrossRef - Diagnosis and Management of Right Colonic Diverticular Disease: A Review
Francesco Ferrara, Jesús Bollo, Letizia V. Vanni, Eduardo M. Targarona
Cirugía Española (English Edition).2016; 94(10): 553. CrossRef - Diagnóstico y tratamiento de la enfermedad diverticular del colon derecho: revisión de conjunto
Francesco Ferrara, Jesús Bollo, Letizia V Vanni, Eduardo M Targarona
Cirugía Española.2016; 94(10): 553. CrossRef - Intraoperative diagnosis of solitary cecal diverticulum not requiring surgery: is appendectomy indicated?
Renol M. Koshy, Abdelrahman Abusabeib, Saif Al-Mudares, Mohamed Khairat, Adriana Toro, Isidoro Di Carlo
World Journal of Emergency Surgery.2016;[Epub] CrossRef - Risk factors for recurrence of right colonic uncomplicated diverticulitis after first attack
Hyoung-Chul Park, Byung Seup Kim, Kwanseop Lee, Min Jeong Kim, Bong Hwa Lee
International Journal of Colorectal Disease.2014; 29(10): 1217. CrossRef - Surgical management of colonic diverticular disease: Discrepancy between right- and left-sided diseases
Heung-Kwon Oh
World Journal of Gastroenterology.2014; 20(29): 10115. CrossRef - Is Conservative Treatment with Antibiotics the Correct Strategy for Management of Right Colonic Diverticulitis?: A Prospective Study
Tae Jung Kim, In Kyu Lee, Jong Kyung Park, Yoon Suk Lee, Youn Si, Hun Jung, Hyung Jin Kim, Sang Chul Lee, Dae Young Cheung, Lee D. Gorden, Seung Taek Oh
Journal of the Korean Society of Coloproctology.2011; 27(4): 188. CrossRef - Management of Right Colon Diverticulitis
Jong Ik Jang, Yang Soo Lim, Jong Woo Choi, Yoon Sik Lee
Journal of the Korean Society of Coloproctology.2010; 26(1): 22. CrossRef - Treatment of Right Colonic Diverticulitis: The Role of Nonoperative Treatment
Ma Ru Kim, Bong-Hyeon Kye, Hyung Jin Kim, Hyeon-Min Cho, Seong Taek Oh, Jun-Gi Kim
Journal of the Korean Society of Coloproctology.2010; 26(6): 402. CrossRef - Right Colonic Diverticulitis
In Kyu Lee
Journal of the Korean Society of Coloproctology.2010; 26(4): 241. CrossRef - A Case of Ascending Colon Diverticulitis with Perforation in a Child
Joon Woo Baek, Jae Young Shin, Jee Hyun Lee, So Young Jung, Ah Young Jung, Jeong Won Kim, Kon Hee Lee
Korean Journal of Pediatric Gastroenterology and Nutrition.2010; 13(2): 193. CrossRef - Laparoscopic and Open Surgery for Right Colonic Diverticulitis
In Kyu Lee, Yoon Suk Lee, Sung Jip Kim, D. Lee Gorden, Dae Youn Won, Hyeung Jin Kim, Hyeun Min Cho, Hae Myung Jeon, Jun-Gi Kim, Seong Taek Oh
The American Surgeon™.2010; 76(5): 486. CrossRef
- Right‐sided acute diverticulitis in a North African country: Presentation and management in one surgical center
- The Clinical Analysis of Colonic Diverticulitis Accompanying Acute Abdomen.
- Song, Joon Ho , Paik, Chong Dae , Lee, Sang Hee , Kim, Han Sun
- J Korean Soc Coloproctol. 2002;18(6):390-396.
- 1,383 View
- 12 Download
-
Abstract
PDF
- PURPOSE
With the gradual changes in diet pattern, the incidence of diverticular disease have progressively increased. The diverticular disease including diverticulitis is difficult to diagnose prior to the operation as it mimics common acute abdominal conditions like acute appendicitis. Also, controversies abound as regards the optimal treatment, ranging from conservative treatment to colon resection. The aim of the present paper was to review diagnosis and treatment strategy followed by a clinical appraisal.
METHODS
We studied retrospectively 101 patients who were diagnosed as colonic diverticulitis for 10 years period between January, 1991 and December, 2000 at Seoul Red Cross Hospital, Dept. of Surgery.
RESULTS
There were 59 males and 42 females. The male to female ratio was 1.4 : 1. During admission, everyone complained abdominal pain as an initial symptom, especially on the right lower quadrant. The right colon was the most common site with single diverticulitis. The diagnosis of diverticulitis was performed by ultrasonography, CT scan, and colon study, barium enema, colonofiberscopy except in 17 cases which were diagnosed preoperatively having appendicitis. Two treatment groups were identified. Group I (n=48) received conservative treatment with or without appendectomy, while group II (n=53) underwent definitive surgery. Overall, there was no difference in clinical outcome except for the duration of antibiotics between two groups.
CONCLUSIONS
In treating uncomplicated diverticulitis, the conservative treatment should be considered at first. Conservative treatment with systemic antibiotics have resulted in a comparable outcome to that of the surgical group with low morbidity and low recurrence rate. Therefore, without serious complications such as hemorrhage, fistula, septic condition, inability to exclude carcinoma, clinical deterioration, young age, right colon diverticulitis, chronic stricture or the use of steroid, we propose that a conservative approach be adopted.
- Treatment Outcome in Patients with Pediatric Encopresis.
- Kim, Jeong Eun , Chung, Soon Sup , Park, Ung Chae
- J Korean Soc Coloproctol. 2002;18(5):294-299.
- 1,291 View
- 18 Download
-
Abstract
PDF
- PURPOSE
The causes of encopresis are complex and multifactorial. Through application of new sophisticated techniques and armamentarium, it has been possible to find more specific aspects of the anorectal function in pediatric patients with refractory defecation disorders. However, quality research of which therapeutic option could be suitable, is still lacking. The current study was designed to assess outcome of treatment according to the treatment algorithm based on the clinical and physiologic findings.
METHODS
22 patients (15 boys, 7 girls) with encopresis were analyzed, retrospectively. For exclusion of the organic cause, barium contrast study and anoscopy were carried out in all cases. Patients were categorized and made treatment algorithm by using leading symptoms and findings of anorectal physiologic tests. Treatment outcomes were analysed in the basis of respective therapeutic options.
RESULTS
Patients were categorized as constipation dominant group (n=15) and incontinence dominant group (n=7). Suggested etipathogeneses were as follows; fecal impaction and/or motility disorder (n=7), overflow incontinence (n=6), sensory defect of the rectum (n=4), puborectalis incoordination (n=3), anal hypertonia (n=2). Treatment options were as follows; conventional therapy (CT) only (n=7), CT plus biofeedback (n=9), CT plus balloon sensory retraining (n=4), and CT plus internal sphincterotomy or Nitroglycerine application (n=2). All patients were undertaken a toilet training and psychologic consultation. Regarding to the therapeutic outcome, 19 (86 percent) of overall 22 patients were improved in the mean period of 2.5 (range, 0.1-7) years follow-up.
CONCLUSIONS
If therapy could be undertaken according to the optional algorithm based on the clinical and physiologic findings, it could be useful guide for clinical decision making to help the therapy. Moreover, through the combination therapy including medication, psychological consultation, and biofeedback treatment, encopretic children achieve acceptable outcome with a long-term compliance.
First
Prev
TOP
