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Case Report
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J Korean Soc Coloproctol. 2006;22(5):346-349.
- Sigmoid Colon Cancer with Isolated Metastasis to the Left Kidney.
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Kim, Hyung Jin , Choi, Ho Joong , Kang, Won Kyung , Oh, Soon Nam , Jung, Chan Kwon , Oh, Seong Taek
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1Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. wonkkang@catholic.ac.kr
2Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
3Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Abstract
- We report the case of a 63-year-old female with sigmoid colon cancer and isolated metastasis to the left kidney at the time of initial diagnosis. An anterior resection of the sigmoid colon and a left nephrectomy were performed. Three cycles of adjuvant chemotherapy consisting of oxaliplatin, 5-fluorouracil, and leucovorin were given, but two months after the surgery, multiple metastases of the liver were detected on a CT scan. The patient refused further treatment and died 5 months after the discovery of an isolated metastasis. An isolated metastasis to the kidney is very rare in clinical practice. A nephrectomy for kidney metastasis has no effect on survival and quality of life, and a nephrectomy may also compromise the choice of chemotherapy agents that require renal clearance; thus, a careful evaluation of renal function is necessary before a nephrectomy. At present, kidney metastasis should be regarded as an advanced metastatic disease, and aggressive chemotherapy, including target therapy, should prolong survival and improve the quality of life. However, when a synchronous or a metachronous renal tumor is suspected, a nephrectomy should be performed for accurate diagnosis and treatment.
Keywords :Sigmoid colon cancer;Kidney metastasis;Nephrectomy;Synchronous cancer
