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Department of Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences, Seoul, Korea.
1Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences, Seoul, Korea.
2Department of Surgery, Colorectal Cancer Center, Kunkuk University Medical Center, Seoul, Korea.
© 2014 The Korean Society of Coloproctology
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Implication of Microsatellite Instability in Chinese Cohort of Human Cancers
Clinical features of the entire study cohort
Values are presented as mean ± standard deviation or number (%).
MSI-H, microsatellite instability-high; MSI-L/S, microsatellite instability-low/stable; CRC, colorectal cancer; CEA, carcino-embryonic antigen.
Pathological features of the entire study cohort
Values are presented as mean ± standard deviation or number (%).
MSI-H, microsatellite instability-high; MSI-L/S, microsatellite instability-low/stable; WD/MD, well differntiation/moderate differentiation; PD/MUC, poor differentiation/mucinous carcinoma.
Adjuvant chemotherapy after curative resection
Values are presented as number (%).
MSI-H, microsatellite instability-high; MSI-L/S, microsatellite instability-low/stable; FL, 5-FU, leucovorin; FOLFOX4, 5-FU, leucovorin, oxaliplatin.
aP = 0.69. bP = 0.27.
Location of recurrence
Values are presented as number (%).
Cox proportional hazard analysis of DFS in the stage II subgroup by using univariate and multivariate analyses
DFS, disease-free survival; HR, hazard ratio; CI, confidence interval; MSI-H, microsatellite instability-high; CEA, carcino-embryonic antigen; PD, poor differentiation; MUC, mucinous carcinoma.
Values are presented as mean ± standard deviation or number (%). MSI-H, microsatellite instability-high; MSI-L/S, microsatellite instability-low/stable; CRC, colorectal cancer; CEA, carcino-embryonic antigen.
Values are presented as mean ± standard deviation or number (%). MSI-H, microsatellite instability-high; MSI-L/S, microsatellite instability-low/stable; WD/MD, well differntiation/moderate differentiation; PD/MUC, poor differentiation/mucinous carcinoma.
Values are presented as number (%). MSI-H, microsatellite instability-high; MSI-L/S, microsatellite instability-low/stable; FL, 5-FU, leucovorin; FOLFOX4, 5-FU, leucovorin, oxaliplatin. aP = 0.69. bP = 0.27.
Values are presented as number (%).
DFS, disease-free survival; HR, hazard ratio; CI, confidence interval; MSI-H, microsatellite instability-high; CEA, carcino-embryonic antigen; PD, poor differentiation; MUC, mucinous carcinoma.