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Journal of the Korean Society of Coloproctology 2006;22(5):346-349.
Sigmoid Colon Cancer with Isolated Metastasis to the Left Kidney.
Kim, Hyung Jin , Choi, Ho Joong , Kang, Won Kyung , Oh, Soon Nam , Jung, Chan Kwon , Oh, Seong Taek
1Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. wonkkang@catholic.ac.kr
2Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
3Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
We report the case of a 63-year-old female with sigmoid colon cancer and isolated metastasis to the left kidney at the time of initial diagnosis. An anterior resection of the sigmoid colon and a left nephrectomy were performed. Three cycles of adjuvant chemotherapy consisting of oxaliplatin, 5-fluorouracil, and leucovorin were given, but two months after the surgery, multiple metastases of the liver were detected on a CT scan. The patient refused further treatment and died 5 months after the discovery of an isolated metastasis. An isolated metastasis to the kidney is very rare in clinical practice. A nephrectomy for kidney metastasis has no effect on survival and quality of life, and a nephrectomy may also compromise the choice of chemotherapy agents that require renal clearance; thus, a careful evaluation of renal function is necessary before a nephrectomy. At present, kidney metastasis should be regarded as an advanced metastatic disease, and aggressive chemotherapy, including target therapy, should prolong survival and improve the quality of life. However, when a synchronous or a metachronous renal tumor is suspected, a nephrectomy should be performed for accurate diagnosis and treatment.
Key Words: Sigmoid colon cancer; Kidney metastasis; Nephrectomy; Synchronous cancer


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