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Original Article
The Effect after Intra-dermal Methylene Blue, Hydrocortisone, Lidocaine Injection Therapy for Intractable, Idiopathic Pruritus Ani.
Kim, Joo Hyung , Lee, Yong Pyo
Journal of the Korean Society of Coloproctology 2005;21(2):71-75

1Hanvit Colorectal Clinic, Suwon, Korea. surgeons@hanvithospital.com
2Department of Surgery, Guri Jeil Hospital, Guri, Korea.
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PURPOSE
Idiopathic pruritus ani is a common and embarrassing proctological condition which can be very difficult to treat. In this study, we documented our results with methylene blue intra-dermal injection in patients with intractable idiopathic pruritus ani.
METHODS
5-ml 1% methylene blue, 100-mg hydrocortisone, and 15-ml 1% lidocaine were injected into the perianal skin of 21 patients with idiopathic pruritus ani which had proved refractory to standard care. Clinical follow-up was undertaken.
RESULTS
After one injection of the above solution, 15 (71.4%) of the patients were rendered symptom free. Repeat injection in the initial non- responders ultimately rendered another four. 19 (total: 90.5 %) of the patrents symptom free. Morbidity was 0%.
CONCLUSION
This study has shown that intra-dermal methylene blue injection is a safe, simple, and efficient method of treating intractable, idiopathic pruritus ani.

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