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Journal of the Korean Society of Coloproctology 2002;18(6):419-422.
Papillary Serous Carcinoma in Rectum-a Case of Complete Remission of Bulky Pelvic Disease after Platinum-paclitaxel Combination Chemotherapy.
Choi, Jung Hun , Yoon, Suk Hyun , Yoon, Wan Hee
Department of Surgery, College of Medicine, Chungnam National University, Daejeon, Korea. whyoon@cnu.ac.kr
Abstract
Papillary serous carcinoma of the peritoneum (PSCP) is a primary tumor of peritoneal lining (mesothelioma) of the abdomen and is histologically difficult to differentiate from papillary serous carcinoma of the ovary. It is very rare tumor that involves the surface of the pelvic and/or abdominal peritoneum. Most patients with this tumor have been treated with optimally surgical cytoreduction and postoperative chemotherapy. However, long term survival has not been achieved in many studies. In recent years, platinum-paclitaxel combination therapy was reported as a effective initial therapy for recurrent PSCP. We have experienced one case of recurrent PSCP which was successfully treated with heptaplatin and paclitaxel. We report the toxicity and long term result of the patient.
Key Words: Recurrent papillary serous carcinoma; Cytoreduction; Heptaplatin
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