A Case of Granular Cell Tumor in the Perianal Region.

, Hwang, Do Yeon; , Song, Seok Kyu; , Lee, Jong Ho; , Kim, Hyun Shig; , Lee, Jong Kyun; , Lee, Jung Dal; , Kim, Kwang Yun

Case Report

Journal of the Korean Society of Coloproctology 2001;17(2):108-111.

Hwang, Do Yeon , Song, Seok Kyu , Lee, Jong Ho , Kim, Hyun Shig , Lee, Jong Kyun , Lee, Jung Dal , Kim, Kwang Yun

¹Department of Surgery, Song Do Colorectal Hospital, Seoul, Korea. jeilgs@chollian.net
²Department of Pathology, Song Do Colorectal Hospital, Seoul, Korea.

Abstract

Since granular cell tumor was first described by Abrikossoff in 1926, it has been known as a rare disease. The histogenesis of this tumor is still controversial, but the origin is thought to be from a Schwann cell. About one third of the tumors occur in the tongue, and uncommonly in the perianal region. We report a case of granular cell tumor that developed in the perianal region. The tumor grew slowly for 5 years and was removed by a local excision. This tumor showed positive staining with neuron-specific enolase (NSE).

Key Words: Granular cell tumor; Perianal region; Local excision; Immunohistochemical study; Neuron- specific enolase