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Case Report
A Case of Secondary Amyloid Colitis in Rheumatoid Arthritis.
Cho, Jae Wan , Chae, Hiun Suk , Im, Kuk Hee , Kim, Tae Ho , Lee, Gang Mun , Kim, Sung Soo , Lee, Chang Don , Choi, Gyu Yong , Chung, In Sik , Sun, Hee Sick , Maeng, Yi So , An, Chang Hyuk
Journal of the Korean Society of Coloproctology 2000;16(2):125-130

1Department of Internal Medcine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
2Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
3Department of General Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
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Abstract

Amyloidosis is known as a disease caused by the deposition of a insoluble and fibrous amyloid protein in the extracellular space of various organs and tissue. Intestinal amyloid deposition may develop motility disturbance, malabsorption, bleeding and perforation. A 70-year old woman with lower abdominal pain, watery diarrhea was admitted and had the past history of diabetes mellitus, hypertension for 8 years and rheumatoid arthritis for 10 year. On colonoscopic examination for evaluation of diarrhea, multiple edematous and shallow ulcers was found from distal sigmoid to terminal ileum. A green colored positive birifringent stained amorphous material was found in polarizing microscopy of colon biopsy specimen stained with Congo-red on microscopic examination,. We report a case of amyloidosis causing colon ulcers confirmed by colonoscopic biopsy with review literature.

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