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Leiomyosarcoma is the most commonly nonepithelial gastrointestinal malignancy. It may arise from the smooth muscle of the muscularis propria, muscularis mucosa, or blood vessels. This malignant tumor is most common seen in the fifth and sixth decades, although it may occur in infants and children. Leiomyosarcoma of the large intestine are unusual neoplasms, comprising less than 0.1% of all malignancies of the colon and rectum. Leiomyosarcomas in gastrointestinal tract are mostly found 61% in the stomach, 24% in the small bowel, 7% in the rectum, and only 3% in the colon. The survival rates and therapeutic approaches to gastrointestinal leiomyosarcoma vary widely. We experienced a case of recurred rectal leiomyosarcoma in the abdominal wall and report with review of literatures.